COMPLETE ALZHEIMER S CURE
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1 A Supplement to Dr. Micozzi s COMPLETE ALZHEIMER S CURE An All-New, All-Natural Protocol to Protect and Restore Brain Health and Reverse Memory Loss The Best Herbs to Guard and Heal Your Amazing Brain 1
2 Table of Contents Lesson 12: Why Ginkgo FAILS for Dementia Despite Solid Science... 2 Lesson 13: Guarantee TRULY Golden Years Rush to These Three Remedies for Pure Herbal Gold... 3 Lesson 14: Stay Cognitively Strong by Maximizing the ENERGY in EVERY Brain Cell... 5 Lesson 12 Why Ginkgo FAILS for Dementia Despite Solid Science Research studies show that ginkgo biloba extract (GBE) can effectively treat and prevent dementia. And in Europe, doctors widely prescribe it for their dementia patients. But we have very little to show for it in real life medical practice. In fact, GBE doesn t work nearly as well out in the real world as it does in research studies. And German doctors recently set out to determine why. As I ve told you in previous lessons, dementia is a general term to describe decreases in several areas of cognitive function. Including loss of memory, attention, reasoning, and problem-solving abilities. It is age-related and obviously occurs more frequently in people over 65. But unlike age-related memory loss, dementia generally worsens over time. And it significantly impairs a person s work, daily living, social interactions, and relationships. Since mainstream medicine has so little to offer dementia patients, everyone is looking for alternatives. Even mainstream doctors. And in Europe, they widely prescribe ginkgo biloba extract to dementia patients based on years of solid research. In fact, research published over the last 30 years consistently shows that GBE enhances memory and cognitive function. Initially, researchers thought GBE worked because it increases blood flow to the brain. Newer studies suggest that it protects nerve cells from damage. Researchers have found that men and women must take at least 240 mg of ginkgo a day to get results. And they must take it over relatively long periods six months or more to be effective. Unfortunately, as I mentioned earlier, we can t seem to duplicate the success achieved in clinical trials out in the real world. And German scientists think this dosing issue may be one reason why In this analysis, German researchers followed more than 13,000 patients prescribed with ginkgo biloba extract. About 7,000 of them were taking a capsule that contained 120 mg of GBE. A little over 6,000 of them were taking a capsule that contained less than 120 mg of GBE. And just 430 of them were taking the ideal dose of 240 mg per capsule. Interestingly, 240 mg capsules of GBE only became available in 2008 in Germany. So most doctors are still not familiar with prescribing the larger, optimal dose. After six months, researchers found that just 23 percent of the 240 mg capsule group were still taking their daily dose. And just 5.7 percent in the 120 mg group maintained their regimen. And almost none of group that took less than 120 mg maintained it. So, after the optimal six months, very few dementia patients remained under treatment. This study helps explain why we rarely see success with GBE in the real world. Most patients simply don t 2
3 take a strong enough dose for a long enough period of time. And when they don t achieve any real benefits in a timely manner, they stop taking it. If real world patients won t, or can t, take enough of a theoretically effective supplement, how worthwhile is it? Bottom line? We need to look beyond tired, old ginkgo for dementia. We need new remedies that work in real-world scenarios. They need to go to work more quickly and show real benefits sooner. So patients don t give up before they start working. Such remedies do exist (including effective HERBAL remedies) and I talk about them in previous and upcoming lessons. Lesson 13 Guarantee TRULY Golden Years Rush to These Three Remedies for Pure Herbal Gold In ancient cultures, plants were recognized for their potential as MEDICINES as healing herbs. And why not? After all, plants contain biologically active constituents to protect against predators and as a means of survival. And some of those protective properties make them protective for humans particularly for human BRAINS. In this lesson, we ll look at three herbs used for thousands of years in the healing regimens of China and India herbs that modern science is showing are ideal for brain health. The three herbs: turmeric, ginger and berberine. I call them herbal gold because each has a bright, radiant yellow color and because they deliver the golden riches of health and healing TURMERIC (also known as curcumin) is a potent, natural herb you can use to help prevent and manage many medical conditions. And research conducted in 2014 shows it s an incredible brain powerhouse. In the study, scientists from the Monash Asia Institute tracked memory in a group of Taiwanese men and women 60 years or older who had been recently diagnosed with untreated prediabetes. They gave participants 1 gram of turmeric with a morning meal of white bread. They also tested the participants working memory before and after eating the white bread. Amazingly, the researchers discovered this modest amount of turmeric improved the participants working memory for more than six hours following the starchy meal. Experts widely consider working memory as one of the most important mental abilities. It s critical for cognitive functions such as planning, problem solving and reasoning. In fact, I think of working memory as the random access memory (RAM) in your computer. It s required for moment-to-moment executive functioning. In addition, doctors assess a patient s working memory as a way to evaluate overall cognitive function. It s also useful in predicting future impairment as observed in Alzheimer s disease and dementia. Turmeric s bright yellow color comes from the presence of curcumin. And research shows curcumin reduces the risk of dementia. So today s findings out of the Monash Asia Institute should come as no real surprise to anyone who knows the history and science of the spice. One way turmeric/curcumin appears to protect the brain is by balancing blood sugar and metabolism. In fact, curcumin seems to work especially well on cognition in men and women with poor energy metabolism and insulin resistance. Of course, several natural spices, including ginger, seem to have this same kind of effect. So perhaps all the cooks in ancient times in the East were naturally onto something special When they added curry, ginger, and other spices to rice, they slowed digestion and metabolism of all the carbohydrates in the meal. This naturally helped keep their blood sugar balanced while still obtaining calories 3
4 from their traditional cuisine. Of course, with curry you also get the antioxidant, antiinflammatory, brain-boosting, and metabolic-balancing effects of all its potent ingredients. So treat yourself to great Indian food. Dine-in or takeout. Or better yet, cook some traditional Indian dishes at home with curry. If you prefer to get your turmeric/curcumin in a supplement, look for one with 200 to 500 mg of curcumin (Curcuma longa, root extract). Now about that GINGER. New, cutting-edge science published in the Indian Journal of Experimental Biology suggests that ginger may be the ideal natural Alzheimer s disease (AD) treatment. For this new study, researchers found it protects the brain against AD in three specific ways. First, it targets inflammation and oxidation. Previous research shows these two actions cause premature degeneration of neural brain tissues, as we see in AD patients. Second, ginger protects against the development of A-beta, a molecular abnormality in the brain. More specifically, A-beta is a type of improper folding of a key protein that causes neurotoxicity. Plus, we know the presence of A-beta is one of the adverse brain changes that occur in AD patients. A 2013 study in lab animals found that ginger actually reversed dysfunctional behaviors caused by this brain abnormality. Third, ginger seems to work as a natural acetylcholinesterase inhibitor. (Many popular AD drugs work in this way, but they cause terrible side effects.) These inhibitors prevent the enzyme acetylcholinesterase from breaking down acetylcholine, a key neurotransmitter your brain needs for learning and memory. Interestingly, the researchers in the new study found that ginger increases the level of this key neurotransmitter in the brain. Plus, it increases how long the neurotransmitter stays active in the brain. As a result, it stimulates normal brain functions. So how much ginger should you take to help boost your brain function? You can probably tolerate ginger at doses up to 2 grams (2,000 mg) daily. You can add this amount to your foods as a spice. You can also get this amount as a dietary supplement. At this dose, there was no known acute toxicity. I suggest keeping some fresh ginger root in your kitchen year-round. You can sprinkle it on baked goods and include it in beverages. You can slice it into healthy salads. And use it as a garnish for fish, meat and vegetables. Of course, you can also use it when you make your favorite Asian dishes. And shredded ginger makes a great topping for (moderate) servings of ice cream or chocolate dishes. According to this new research, if you make ginger a part of your daily regimen, perhaps your brain WON T go the way of the Gingerbread Man a quarter gone half gone all gone. Same goes for BERBERINE Berberine a naturally occurring plant alkaloid from the barberry bush, used in many Chinese herbal formulations is quickly becoming one of the new darlings of the nutritional medicine world. And the buzz has focused largely on this herbal remedy s ability to balance blood sugar and combat diabetes. But the new research on berberine that caught my eye had nothing to do with blood sugar or diabetes or so I initially thought. Several new studies have shown impressive results using berberine for Alzheimer s. But now that Alzheimer s is emerging as Type III diabetes with high levels of blood sugar and insulin attacking brain cells the link between these two fields of research on berberine makes perfect sense. 4
5 But berberine defends against Alzheimer s not only by helping to regulate blood sugar. New experimental results have found that berberine protects the brain in at least three more distinct ways: 1.) It can safeguard your brain from the dangerous oxidation damage that can eat away at brain tissue. 2.) It targets and destroys memory-killing enzymes that have long been considered key in the development of Alzheimer s. 3.) It promotes healthy blood flow directly to the brain an essential element to conquering dementia. Berberine also seems to be able to block certain nerve receptors, which may partly explain its anti-alzheimer and neurotransmitter-modulating properties. Add these specific actions to berberine s wellestablished blood sugar benefits and it appears that this herb may hold the key to preventing and even slowing the progression of Alzheimer s disease (Type III diabetes) like nothing before it. I recommend 500 mg per day, taken over the course of the day in two or three doses to achieve a steady state. Lesson 14 Stay Cognitively Strong by Maximizing the ENERGY in EVERY Brain Cell Research shows dysfunction of the mitochondria (the parts of cells that produce energy) is a KEY TRIGGER for the development of Alzheimer s. (Beware: this function is poisoned by certain drugs like statins.) This is why confusion and memory-loss are often side effects of many drugs, especially statins that actually interfere with mitochondrial function. In fact, this explains why the drug company Merck actually took out a patent on a statin and coenzyme Q10 combination. mitochondrial function. And it s why I recommend supplementing with 100 mg of CoQ10 daily (ideally in the form of ubiquinol). You can also help ensure your mitochondria are operating optimally by taking a unique herbal combination of aspal (rooibos) combined with dandelion extract. This duo of herbs has REMARKABLE impacts on mitochondria, in terms of cellular energy. Aspal and dandelion also HYDRATE your cells. To understand cellular hydration, it helps to imagine a roaring fire. Your cells make energy through a chemical reaction that s similar to the way a fire creates heat. In a fire, wood, coal or oil combines with oxygen to produce heat. In a cell, glucose (carbohydrate) combines with oxygen to create energy. The byproduct of this process which is called cellular respiration is carbon dioxide and water. And the water formed by cellular respiration called cellular hydration is the main source of water inside the cells. In fact, MOST of the water inside your cells must be made by the cells themselves. Now back to aspal and dandelion. Getting a supplement with aspal and dandelion extract is like throwing more wood onto those cellular hearths. And brain cells that were literally dying of thirst are rehydrated and ready to put more life on your memory, focus and thinking. I recommend taking dandelion extract and the South African herb aspal daily to help stay cognitively AND physically strong. You can find these ingredients in some high-quality dietary supplements. Or in water-soluble powders which you can add to water or another beverage. I recommend products that contain up to 450 mg each of dandelion and aspal, as well as blueberry which I ll tell you about in Lesson 16. CoQ10 is a cofactor that has been shown to boost 5
6 For more about Dr. Micozzi s Complete Alzheimer s Cure Protocol, visit: and ABOUT DR. MICOZZI Marc S. Micozzi, M.D., Ph.D. was the founding editor-in-chief of the first U.S. journal in Complementary and Alternative Medicine and organized and edited the first US textbook in the field, Fundamentals of Complementary & Integrative Medicine in He has published nearly 300 articles in medical literature and is the author or editor of over 25 books. Dr. Micozzi served as Senior Investigator of cancer prevention at the National Cancer Institute, where he published the original research on diet, nutrition, and chronic disease. He continued this line of research as the Associate Director of the Armed Forces Institute of Pathology and Director of the National Museum of Health and Medicine. In recent years, Dr. Micozzi has served as the Founding Director of the Policy Institute for Integrative Medicine in Bethesda, MD, working to educate policy makers, the health professions, and the general public about the opportunities for integrative medicine and the need for clean, clear science within our modern medical establishment. Dr. Micozzi writes a monthly newsletter called Insiders Cures as well as a free e-letter called The Daily Dispatch. Copyright 2016, OmniVista Health Media, L.L.C. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including recording, photocopying, or via a computerized or electric storage or retrieval system without permission granted in writing from the publisher. The information contained herein is obtained from sources believed to be reliable, but its accuracy cannot be guaranteed. All material in this publication is provided for information only and may not be construed as medical advice or instruction. No action or inaction should be taken based solely on the contents of this publication; instead, readers should consult appropriate health professionals on any matter relating to their health and well-being. The information and opinions provided in this publication are believed to be accurate and sound, based on the best judgment available to the authors, and readers who fail to consult with appropriate health authorities assume the risk of any injuries. The publisher is not responsible for errors or omissions. For additional copies or questions, please contact Reader Services at 100 W. Monument Street, Baltimore MD You may also call (630) or send a fax to (410)
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