Functional Phytotherapy for Clinical Success

Transcription

1 Functional Phytotherapy for Clinical Success Kerry Bone Adjunct Professor New York Chiropractic College Disclaimer Integria Healthcare and Standard Process sponsor these webinars to provide health care information to practitioners and to provide them the opportunity to hear about the views, recommendations and experiences of other practitioners. Health related information provided here is not a substitute of medical advice. Integria, Standard Process and the speaker, Kerry Bone, have not evaluated the legal status of any products (except for Standard Process and MediHerb products), services or recommendations with respect to state or federal laws, including scope of practice. Integria, Standard Process and Kerry Bone do not and cannot accept responsibility for errors or omissions or for any consequences from applications of the information provided and makes no warranty, expressed or implied, with respect to the information provided. Recommendations for Standard Process and MediHerb product dosages are those of the speaker and sometimes different than the doses that appear on the product labels. Please refer to the product labels or to the product descriptions found in the product catalogs or on the website for Standard Process and MediHerb dosage recommendations. *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Professor Kerry Bone Kerry Bone is the co-founder and innovation driver at MediHerb, where he serves as Director of Research and Development. In 2016 MediHerb was awarded the American Botanical Council s (ABC s) Varro E. Tyler Award for excellence in Phytomedicinal Research. As part of his educational role, Kerry is Principal of the Australian College of Phytotherapy and also Adjunct Professor at New York Chiropractic College, providing input into their postgraduate applied nutrition program. Kerry is co-author of more than 30 scientific papers on herbal research. He has also written and co-written six popular textbooks on herbal medicine, including his latest, the second edition of Principles and Practice of Phytotherapy which was awarded the 2013 James A. Duke Excellence in Botanical Literature Award by the ABC. Kerry maintains a busy herbal and naturopathic practice in Toowoomba, Queensland, where he has been in continuous service for more than 30 years. In 2015, Kerry s lifelong contribution to the field of herbal medicine was recognized with his receiving the prestigious Lady Cilento award from the complementary medicine industry in Australia. 1

2 Our Topics Success with symptom-based prescribing Functional phytotherapy roots What is functional medicine? Defining functional phytotherapy: key attributes Twelve core strategies of functional phytotherapy 4 Success with symptom-based prescribing 5 Mauro Raffaelli/ CC-BY-SA-3.0 / Boswellia Licorice Tribulus Andrographis Echinacea Root Kava Rhodiola Ashwagandha Horsechestnut St John s Wort Eyebright Gymnema Gotu Kola Ginkgo Korean Ginseng 6 2

3 Boswellia joint health post-exercise musculoskeletal inflammation in general gastrointestinal health best in combination 7 Licorice HPA axis support; adrenal restoration reduces sweet cravings addresses indigestion Image: Raffi Kojian/ CC-BY-SA-3.0 / IMG_2804_rbgs11jan.jpg 8 Tribulus Leaf supports normal reproductive function in men and women also a male tonic: libido and performance menopausal symptoms Image: Raffi Kojian/ CC-BY-SA-3.0 / 9 3

4 Andrographis short-term immune system support upper respiratory support non-cystic acne Image: J.M.Garg / Creative Commons Attribution-Share Alike 4.0 International 10 Echinacea Root immune system support useful as well for treatment, but with Andrographis does not deplete the immune system with continuous use 11 Kava amazingly good for anxiety and difficulty sleeping relaxes muscle, both smooth and skeletal depressed mood if comorbid with anxiety Image: Poyt448, Peter Woodard / Creative Commons Attribution-Share Alike 4.0 International /

5 Rhodiola fatigue, physical stress, convalescence depressed mood improves performance (mental and physical) Image: Σ64 / CC-BY-SA-3.0 / 13 Ashwagandha as for Rhodiola previously but for anxiety, rather than depressed mood, and is a more calming tonic boosts DHEA, testosterone and thyroxin Bone KM, Mills SY. Principles and Practice of Phytotherapy: Modern Herbal Medicine 2 nd edition, Elsevier, UK, 2013 Image: Hari Prasad Nadig, Vinayaraj / CC-BY-SA-2.0 / 14 Horsechestnut varicose vein symptoms and hemorrhoids unexplained balance issues soft tissue compression syndromes Image:

6 St John s Wort gold standard evidence for low mood can be effective for exercise-related nerve pain immune support Image: Bob Peterson/ CC-BY-SA-2.0 / 16 Eyebright for upper respiratory system relief good also for dry, irritated eyes best combined with Golden Seal Image: Enrico Blasutto/ Creative Commons Attribution-Share Alike 3.0 Unported / 17 Gymnema supports the endocrine pancreas long- and short-term effects on blood sugar metabolism reduces sweet cravings Image: Slick-o-bot / CC-BY-SA-2.0 /

7 Gotu Kola supports natural healing by promoting connective tissue also benefits the microcirculation is a proven brain tonic varicose vein symptoms and hemorrhoids Image: Forest & Kim Starr / CC-BY-SA-3.0 Unported / 19 Ginkgo good for focus and short-term memory age-related cognitive decline also benefits the microcirculation Image: 20 Korean Ginseng fatigue, physical stress, convalescence improves performance (mental and physical) also a male tonic: libido and performance long-term immune system support supports the heart Image: FloralFarm GmbH/Katharina Lohrie/ CC-BY-SA-3.0 Unported /

8 Functional Phytotherapy James Diedrick? 2 2 Roots: Thomsonian Medicine 1. Health follows from obeying natural laws 2. Disease is an obstruction or diminution of vital energy 3. It is caused by violation of natural laws 4. Symptoms, such as fever, are due to the effect of the disease and are not the disease itself 5. Disease has only one basic type of cure to remove obstructions or restore vital energy using substances that act in harmony with natural laws and the vital energy 23 Thomsonian Medicine 6. In doing so one or more of the following effects should be accomplished: a) Relaxation b) Contraction c) Stimulation d) Soothing e) Nourishing f) Neutralization Im age: Lloyd, John Uri; Waterhouse, Benjamin "Life and medical discoveries of Samuel Thomson, and a history of the Thomsonian materia medica, as shown in 'The new guide to health,' (1835) and the literature of that day". Cincinnati, O., J.U. & C.G. Lloyd/ / PD-US 24 8

9 Physiomedicalism Physiomedicalists were neo-thomsonians Thurston (1900) was greatly influenced by the research findings on the autonomic nervous system He extended basic concepts into an elaborate therapeutic system (somewhat inaccessible to the modern reader) 25 Functional Medicine Addresses the underlying causes of disease Uses a systems-oriented approach Is patient-centered rather than disease-centered (the whole person, not just an isolated set of symptoms) www. functionalmedicine.org Image: 26 Functional Medicine History together with genetic, environmental and lifestyle factors are paramount: the matrix Supports the unique expression of health and vitality for each individual 27 9

10 Functional Phytotherapy 1. Understanding diseases as disordered processes of normal physiology 2. Mosaic diseases: the individual story counts most 3. Complex interventions for complex multifactorial disorders (network pharmacology) 4. Therapy based on 12 core strategic targets 5. But the key over-riding consideration is to support the tissue 28 Mosaic Disease Concept first proposed by Irvine Page in 1950 in the context of hypertension 1 Later in 1989 Yehuda Shoenfeld coined the term for autoimmune disease (AiD) 2 1.Page IH. Hypertension 1982; 4(2): Shoenfeld Y, Isenberg DA. Immunol Today 1989; 10(4): Mosaic Disease Principles A syndrome or disease differs in expression shares many common factors (pieces or tiles) Each piece is a causative factor in the disease Each patient is a unique picture Due to the random (stochastic) combination of causative factors THE PATIENT S STORY IS PARAMOUNT 30 10

11 The Three P s of Causation Predisposing e.g. genetics Precipitating e.g. pathogens Perpetuating e.g. maladaptive stress response 31 Applying the OST Rule Overlap therapeutic activity use complex treatments Sequence treatments not everything at once Triage set priorities Image: UVM Scribe/ CC-BY-SA-3.0 / 32 Complex Interventions for Complex Disorders Multiple factors require multiple interventions Determined for each patient by their case history Targeting just one point in a pathophysiological network and completely shutting it down risks side effects and does not resolve the disease 33 11

12 Herbs as Inherently Complex Interventions Gertsch observed that herbal extracts might be complex but are in fact intelligent mixtures of secondary plant metabolites shaped by evolutionary pressures He notes the concept of network pharmacology, as originally proposed by Hopkins Gertsch J. Planta Med 2011; 77(11): Functional Phytotherapy The 12 core strategies 1. Support key endocrine responses: HPA axis thyroid pancreatic beta cells enteroendocrine cells male/female as appropriate Image: BrianMSweis/ CC-BY-SA-3.0 Unported / 35 Functional Phytotherapy 2. Eliminate naturally occurring pathogens 3. Protect and re-energize cells boost cellular protection (cytoprotection) lower danger signals enhance mitochondrial function and biogenesis 4. Detoxify and prime Nrf2 responses 36 12

13 Functional Phytotherapy 5. Enhance nerve function restore healthy nervous system function improve sleep quality and time asleep 6. Improve circulatory flow macrocirculation and blood quality microcirculation and endothelial health promote healing 37 Functional Phytotherapy 7. Eliminate dysbiosis and promote a healthy microbiome 8. Optimize digestive function 9. Optimize and balance immune function 10. Eliminate chronic inflammation response Image: Tony Webster/ 38 Functional Phytotherapy 11. Improve and enhance natural barriers: gastric acid and gut wall barrier respiratory skin 12. Address metabolic imbalances 39 13

14 Right Targets: Lead to Right Protocols Bone K, Mills S. Principles and Practice of Phytotherapy 2 nd Edition, 2013, Elsevier, Edinburgh 40 Concluding Remarks Even a novice can achieve remarkable results with symptom-based prescribing, especially if using herbs that deliver in formulations with inbuilt clinical experience The next step is functional phytotherapy: 12 core strategies and 5 key principles, with some introductory examples, have been outlined 41 14