Reyssouze, France Milan, Italy Palafolls, Spain
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1 Healing by Nature
2 Uncompromising solutions Drawing on decades of experience and with an uncompromising commitment to quality, Naturex is a global market leader in the supply of natural solutions, tailored products and processes to meet the precise specifications of customers. Reyssouze, France Milan, Italy Palafolls, Spain
3 The science of Nature Naturex is specialized in the identification, development and production of plant extracts, purified molecules and excipients for pharmaceuticals. Traditional and innovative offer Naturex has been manufacturing botanical extracts for more than twenty years. Its expertise in the pharmaceutical industry was expanded with the strategic acquisition of two companies: Hammer Pharma and Burgundy (formerly Dr Vinyals laboratories). Today, Naturex is proud to perpetuate the traditional knowledge of these companies and to continue the philosophy of developing new extracts. Naturex has a vast range of Active Pharmaceutical Ingredients (APIs) that are backed by complete Active Substance Master Files (ASMF) in ectd format (Electronic Common Technical Document). In addition, Naturex is also able to provide contract manufacturing for APIs. Mastering industrial know-how Naturex owns 3 GMP factories across Europe, allowing for the manufacture of various pharmaceutical ingredients, using the strictest technologies, from extraction to blending. Each site has its own analytical laboratory in order to rigorously control the entire process, from raw material through to manufacturing. Thanks to its remarkable industrial capabilities and technical know-how, Naturex is able to provide 3 kinds of pharmaceutical product. Herbal drug preparations made from an extraction process in a dry or liquid form. Pure substances obtained by purification. Excipients for taste improvement (bitterness masking, sweetness) that help to minimize the unwanted and unpleasant tastes of some drugs. Expertise and support A dedicated team of pharmacists, botanists and phytochemists is focused on developments. Naturex API specifications and associated ASMF/DMF have been developed to comply with the current monographs, easing their registration under the Traditional Use / Well Established Use scheme in Europe. We have experienced and knowledgeable teams available to help customers with their new product developments, either in APIs or excipients from the sourcing of the raw materials through to the marketing authorization process.
4 Herbal. Manufacturing. Expertise. Raw material Reliable raw material supply Naturex global sourcing capabilities Compliance with Good Agricultural and Collection Practices (GACP) Full traceability Development Dedicated Pharmaceutical development team for: Phytochemical identification Stability evaluation Method of analysis development and validation Tailor-made developments Production GMP manufacturing capabilities and technologies: Extraction (water, ethanol, methanol) Purification Drying (spray dryer, fluid bed dryer, vacuum belt dryer) Granulation Contract manufacturing / Toll manufacturing are available for a customized solution Product Ingredients adapted to your needs Herbal drug preparation > Dry extract > Liquid extract > Oily extract Pure substance Excipient Regulatory affairs Regulatory for a successful marketing authorization application ASMF in ectd format Herbal drug preparation compliant for a registration under Traditional Use / Well Established Use regulation Dedicated support to obtain marketing authorization
5 Ingredients extracted from Nature Active Pharmaceutical Ingredients by therapeutic area Cough and cold Echinacea Goldenseal Astragalus Pau d arco Mouth and throat disorders Raspberry Goldenseal Enoxolone Skin disorders and minor wounds Burdock Gotu kola Enoxolone Gastrointestinal disorders Dandelion Milk thistle Goldenseal Peppermint Pain and inflammation Devil s claw Nettle Celery Venous circulatory disorders Horse Chestnut Gotu kola Migraine Feverfew Eye discomfort Eyebright Sleep disorders and mental stress Valerian Lemon Balm Hops Passion flower Rhodiola St John s wort Heart health Hawthorn Fatigue and weakness Astragalus Rhodiola Gynaecology disorders Black cohosh Wild Yam Chasteberry Raspberry Urinary tract disorders Nettle Burdock Horsetail Dandelion Saw palmetto Sexual disorders Muira Puama Tribulus Key to ingredients Herbal drug preparation: Product obtained after a manufacturing treatment of a herbal drug Pure substance: Isolated molecule obtained by purification Pharmaceutical excipients Effect Thaumatin Monoammonium Glycyrrhizinate Off-taste masker Off-taste masker and sweetener
6 EUROPE / AFRICA AMERICAS ASIA / PACIFIC / MIDDLE EAST FRANCE - GLOBAL HEADQUARTERS Phone +33 (0) naturex@naturex.com THE AMERICAS - US HEADQUARTERS Phone naturex.us@naturex.com AUSTRALIA Phone naturex.au@naturex.com BENELUX Phone naturex.be@naturex.com GERMANY Phone +49 (0) naturex.de@naturex.com ITALY Phone naturex.it@naturex.com MOROCCO Phone +212 (0) naturex.ma@naturex.com POLAND Phone naturex.pl@naturex.com RUSSIA Phone +7 (495) naturex.ru@naturex.com SPAIN Phone naturex.es@naturex.com BRAZIL Phone +55 (11) naturex.br@naturex.com CANADA Phone naturex.ca@naturex.com MEXICO Phone +52 (55) naturex.mx@naturex.com CHINA Phone naturex.cn@naturex.com DUBAI Phone naturex.ae@naturex.com JAPAN Phone +81 (0) naturex.jp@naturex.com KOREA Phone naturex.kr@naturex.com SINGAPORE Phone naturex.sg@naturex.com THAILAND Phone naturex.th@naturex.com Made with vegetable-based inks October 2012 edition UK Phone +44 (0) naturex.uk@naturex.com The natural ingredients made by our Food & Beverage business unit improve the organoleptic characteristics (colour, flavour, taste, texture ) and nutritional properties of finished products. A business unit specialized in the development of botanical extracts and natural ingredient concepts backed by scientific studies for pharmaceutical, dietary supplement and nutraceutical applications. A business unit specialized in the development of natural ingredient concepts backed up with biological studies, botanical extracts that have been specifically formulated and functional ingredients for cosmetic applications.
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