CBD PURE OPIOID RECOVERY FORMULA 600mg Reduce Opioid withdrawal symptoms, Non-narcotic painkiller

Transcription

1 OUR MISSION To ensure patients have access to consistently high quality therapeutic products rooted in science and not folklore WHAT ARE OUR GOALS? Produce high quality, tested and verified therapeutic medicine to address a variety of medical conditions Ensure the patient gets better, not high Educate and advocate the larger community on the medical benefits of cannabis Bridge the gap between what is medically necessary and what is actually available for patients INITIAL PRODUCT LINE OPIOID RECOVERY FORMULA 1200mg 1:1 Reduce Opioid withdrawal symptoms, Non-narcotic painkiller PAIN RELEAFER 1200mg 1:1 Non-Narcotic painkiller MIGRAINE RELEAFER 1200mg 1:1 Reduce the frequency and intensity of chronic migraines GI ASSIST 1200mg 1:1 Reduce/Resolve GI conditions such as IBS, GERD, UC, CROHNS MUSCLE & JOINT OINTMENT 200mg Treats deep muscle and joint pain CBD PURE OPIOID RECOVERY FORMULA 600mg Reduce Opioid withdrawal symptoms, Non-narcotic painkiller CBD PURE PAIN RELEAFER 600mg Non-narcotic painkiller CBD PURE MIGRAINE RELEAFER 600mg Reduce the frequency and intensity of chronic migraines CBD PURE GI ASSIST 600mg Reduce/Resolve GI conditions such as IBS, GERD, UC, CROHNS CBD PURE MUSCLE & JOINT OINTMENT 600mg Treats deep muscle and joint pain AVAILABLE SOON: Products will be available in convenient, fast acting and, easy to dose strips and suppositories. CBD Pure products; available at various locations including our Evaluation Centers. CBD / THC products; coming to a dispensary near you. For complete list of locations visit drburnsreleaf.com WHAT SETS DRBURNS RELEAF PRODUCTS APART? Physician formulations are based on over six years of significant clinical experience with medical marijuana patients Formulations designed to give fast, reliable results and include other botanicals in addition to cannabis to target specific conditions Based on scientific studies Simplified / effective dosing guidelines and product labeling WHO IS DR. BURNS? Dr. Elaine Burns, founder and medical director of Southwest Medical Marijuana Evaluation Center is one of the state s most qualified experts in her field, making her a trusted and valuable resource for other physicians, patients and the news media. After noting a gap between what physicians recommend for their patient and what is available, she created DrBurns ReLeaf, a physicianformulated line of cannabis and other botanical-infused products that assures a consistent quality and bridges this gap.

2 Table of Contents THC / CBD PRODUCT LINE FORMULAS... 1 OPIOID RECOVERY FORMULA 1200 mg 1: PAIN ReLeafer 1200 mg 1: MIGRAINE ReLeafer 1200 mg 1: GI ASSIST 1200 mg 1: Muscle & Joint Ointment 200 mg CBD ONLY PRODUCT LINE FORMULAS CBD PURE 600 mg CBD PURE OPIOID RECOVERY FORMULA 600 mg CBD PURE PAIN ReLeafer 600 mg CBD PURE Migraine ReLeafer 600 MG CBD PURE GI ASSIST 600 mg CBD PURE Muscle & Joint Ointment 200 mg... 22

3 THC / CBD PRODUCT LINE FORMULAS Page 1 of 22

4 OPIOID RECOVERY FORMULA 1200 mg 1:1 USES: This formula combines Cannabis (the whole plant extract) along with other botanicals to create a safe, effective, and economical treatment option to reduce Non-life-threatening Opioid withdrawal symptoms such as; Body aches & pains, Restlessness, Anxiety, Insomnia, Nausea This formula is intended for short term use only; use only during acute withdrawal and recovery phases. (Maximum of 45 consecutive days) For ongoing support, switch to DrBurns Pain ReLeafer. MECHANISMS OF ACTION: Analgesic (reduces pain) Adaptogen (improves body s ability to adapt to stress, restores balance, increases energy) Sedative (promotes calm, induces sleep) Nervine (calms the nerves) Anti-Emetic (decreases nausea & vomiting) Anxiolytic (reduces anxiety) Anti-depressant (reduces depression) Increase GABA (calming neurotransmitter, muscle relaxer) Antispasmodic (reduces muscle spasms) INGREDIENTS: THC 600 MG, CANNABIDIOL 600 MG THC & Cannabidol concentrate, Kosher Vegetable Glycerin, Organic Coconut Oil, Flavoring Proprietary Formula (Withania Somnifers, Astragulus Membranaceus, Valerian Officinalis, Avena Sativa) DOSING SUGGESTION(S): 1 drop = 1mg THC & 1 mg CBD, ½ dropper = 10mg THC & 10mg CBD, full dropper = 20mg THC & 20mg CBD Adults: Starting dose 2 drops (2mg) under tongue. Can increase in increments of 1 drop (1mg) until you reach a dose that provides optimum symptom relief. Once you have titrated your dose to achieve optimum symptom relief, you can adjust your dose according to how you are feeling on a day-to-day basis. Hold for 60 secs then swallow. Page 2 of 22

5 Typically dosed in the evening due to the formulation containing THC & other botanicals. Caution if used during the day if driving or operating dangerous machinery. Maximum daily dose = 35mg CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Avoid use in Pregnancy & Lactation. Avoid use of this formula with: alcohol, Xanax, Benzodiazepines, Sedatives (e.g. Fentanyl, Morphine) Caution using this formula with other medications that are substrates of the Cytochrome P450 3A4 enzyme: e.g. Anxiolytics, Anti-depressants, Hypnotics and, many others. Do Not drive or operate dangerous machinery after taking this formula. Discontinue this formula at least 2 weeks before a scheduled surgery. POSSIBLE SIDE EFFECTS: THC doses greater than 5mg/5% could cause; anxiety, agitation, paranoia, increased heart rate, nausea, vomiting, headache in some people. Discontinue use if any of these occur and take 20mg of CBD PURE. Seek Medical attention if symptoms continue or worsen. Discontinue use and consult your physician if any of the following symptoms occur: headache, excitability, uneasiness, insomnia Page 3 of 22

6 PAIN ReLeafer 1200 mg 1:1 USES: This formula combines Cannabis (the whole plant extract) along with other botanicals to create a safe, effective, and economical treatment option as an Opioid Painkiller Alternative. This formula is a non-narcotic painkiller combination working together to reduce moderate to severe pain conditions. Particularly effective for (but not limited to): osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, muscle pain (e.g. Fibromyalgia), chronic headaches, degenerative disc disease (e.g. low back pain), degenerative joint disease. MECHANISMS OF ACTION: Analgesic (relieves pain) Anti-inflammatory Anti-Arthritic Antispasmodic (reduces muscle spasms) Adaptogen (improves body s ability to adapt to stress, restores balance, increases energy) Anxiolytic (reduces anxiety) Sedative (promotes calm, induces sleep) INGREDIENTS: THC 600 MG, CANNABIDIOL 600 MG THC & Cannabidol concentrate, Kosher Vegetable Glycerin, Organic Coconut Oil, Flavoring, Proprietary Formula (Withania Somnifers, Salix Alba) DOSING SUGGESTION(S): 1 drop = 1mg THC & 1 mg CBD, ½ dropper = 10mg THC & 10mg CBD, full dropper = 20mg THC & 20mg CBD Adults: Starting dose 2 drops (2mg) under tongue. Can increase in increments of 1 drop (1mg) until you reach a dose that provides optimum symptom relief. Once you have titrated your dose to achieve optimum symptom relief, you can adjust your dose according to how you are feeling on a day-to-day basis. Hold for 60 secs then swallow. Typically dosed in the evening due to the formulation containing THC & other botanicals. Caution if used during the day if driving or operating dangerous machinery. Maximum daily dose = 35mg Page 4 of 22

7 Seizures (adults & minors); May use 1 drop of this formula along with the recommended dose of CBD Pure (see product info for dosing) CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Avoid use in Pregnancy & Lactation. Avoid use of this formula with: alcohol, Xanax, Benzodiazepines, Sedatives (eg Fentanyl, Morphine), Aspirin Caution using this formula with other medications that are substrates of the Cytochrome P450 3A4 enzyme: e.g. Anxiolytics, Anti-depressants, Hypnotics and, many others. Do Not drive or operate dangerous machinery after taking this formula. Discontinue this formula at least 2 weeks before a scheduled surgery. Use Caution if you have the following conditions: kidney disease, bleeding disorder, aspirin sensitivity POSSIBLE SIDE EFFECTS: THC doses greater than 5mg/5% could cause; anxiety, agitation, paranoia, increased heart rate, nausea, vomiting, headache in some people. Discontinue use if any of these occur and take 20mg of CBD PURE. Seek Medical attention if symptoms continue or worsen. May result in a change in bleeding time for anyone with a bleeding disorder / taking anti-coagulants have your bleeding times checked regularly while using this formula. Page 5 of 22

8 MIGRAINE ReLeafer 1200 mg 1:1 USES: This formula combines Cannabis (the whole plant extract) along with other botanicals to create a safe, effective, and economical treatment option for chronic migraine & headache conditions. Use this formula prophylactically (as a prevention) to reduce the frequency and intensity of chronic migraines and cluster & tension headaches. This formula may also be good for tinnitus and vertigo. MECHANISMS OF ACTION: Analgesic (relieves pain) Anxiolytic (reduces anxiety) Sedative (promotes calm, induces sleep) Anti-inflammatory Anti-spasmodic Anti-depressant INGREDIENTS: THC 600 MG, CANNABIDIOL 600 MG THC & Cannabidol concentrate, Kosher Vegetable Glycerin, Organic Coconut Oil, Flavoring, Proprietary Formula (Tanacetum Parthenium, Lavendula Officinalis) DOSING SUGGESTION(S): 1 drop = 1mg THC & 1 mg CBD, ½ dropper = 10mg THC & 10mg CBD, full dropper = 20mg THC & 20mg CBD Adults: Starting dose 2 drops (2mg) under tongue. Can increase in increments of 1 drop (1mg) until you reach a dose that provides optimum symptom relief. Once you have titrated your dose to achieve optimum symptom relief, you can adjust your dose according to how you are feeling on a day-to-day basis. Hold for 60 secs then swallow. Typically dosed in the evening due to the formulation containing THC & other botanicals. Caution if used during the day if driving or operating dangerous machinery. Maximum daily dose = 35mg Page 6 of 22

9 CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Avoid use in Pregnancy & Lactation. Avoid use of this formula with: alcohol, Xanax, Benzodiazepines, Sedatives (eg Fentanyl, Morphine) Caution using this formula with other medications that are substrates of the Cytochrome P450 3A4 enzyme: e.g. Anxiolytics, Anti-depressants, Hypnotics and, many others. Caution using this formula with other medications that are substrates of the following Cytochrome P450 enzymes: CYP1A2, CYP2C9, CYP2C19. Caution using this formula with anti-coagulant medications. Do Not drive or operate dangerous machinery after taking this formula. Discontinue this formula at least 2 weeks before a scheduled surgery. Caution if you have a bleeding disorder; may increase bleeding time. POSSIBLE SIDE EFFECTS: THC doses greater than 5mg/5% could cause; anxiety, agitation, paranoia, increased heart rate, nausea, vomiting, headache in some people. Discontinue use if any of these occur and take 20mg of CBD PURE. Seek Medical attention if symptoms continue or worsen. Other possible side effects might include upset stomach, heartburn, diarrhea, constipation, bloating, flatulence, nausea, and vomiting, nervousness, dizziness, headache, trouble sleeping, joint stiffness, tiredness, menstrual changes, rash, pounding heart, and weight gain. If you experience any of these rare side effects discontinue this formula and consult with your physician. May result in a change in bleeding time for anyone with a bleeding disorder / taking anti-coagulants have your bleeding times checked regularly while using this formula. Page 7 of 22

10 GI ASSIST 1200 mg 1:1 USES: This formula combines Cannabis (the whole plant extract) along with other botanicals to create a safe, effective, and economical treatment option designed to reduce/resolve GI conditions such as IBS, Dyspepsia, Ulcerative Colitis, Crohn s, GERD MECHANISMS OF ACTION: Anxiolytic (reduces anxiety) Anti-depressant (reduces depression) Sedative (promotes calm, induces sleep) Analgesic (reduces pain) Nervine (calms the nerves) Anti-Emetic (decreases nausea & vomiting) Antispasmodic (reduces smooth muscle spasms) Anti-inflammatory Astringent (improves digestion, eliminates diarrhea) INGREDIENTS: THC 600 MG, CANNABIDIOL 600 MG THC & Cannabidol concentrate,kosher Vegetable Glycerin, Organic Coconut Oil, Flavoring, Proprietary Formula (Matricaria Chamomilla, Mentha Piperita, Achillea Millefolium) DOSING SUGGESTION(S): 1 drop = 1mg THC & 1 mg CBD, ½ dropper = 10mg THC & 10mg CBD, full dropper = 20mg THC & 20mg CBD Adults: Starting dose 2 drops (2mg) under tongue. Can increase in increments of 1 drop (1mg) until you reach a dose that provides optimum symptom relief. Once you have titrated your dose to achieve optimum symptom relief, you can adjust your dose according to how you are feeling on a day-to-day basis. Hold for 60 secs then swallow. Typically dosed in the evening due to the formulation containing THC & other botanicals. Caution if used during the day if driving or operating dangerous machinery. Maximum daily dose = 35mg Page 8 of 22

11 CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Avoid use in Pregnancy & Lactation. Avoid use of this formula with: alcohol, Xanax, Benzodiazepines, Sedatives (eg Fentanyl, Morphine) Avoid using this formula with anti-coagulant medications. Caution using this formula with other medications that are substrates of the Cytochrome P450 3A4 enzyme: e.g. Anxiolytics, Anti-depressants, Hypnotics and, many others. Caution using this formula with other medications that are substrates of the following Cytochrome P450 enzymes: CYP1A2, CYP2C9, CYP2C19. Do Not drive or operate dangerous machinery after taking this formula. Discontinue this formula at least 2 weeks before a scheduled surgery. Caution if you have a bleeding disorder; may slow blood clotting time. Caution if you have any condition that might be made worse by exposure to estrogen, may have an estrogen like effect. POSSIBLE SIDE EFFECTS: THC doses greater than 5mg/5% could cause; anxiety, agitation, paranoia, increased heart rate, nausea, vomiting, headache in some people. Discontinue use if any of these occur and take 20mg of CBD PURE. Seek Medical attention if symptoms continue or worsen. Page 9 of 22

12 Muscle & Joint Ointment 200 mg USES: This formula combines Cannabis (the whole plant extract) along with other botanicals to create a safe, effective, and economical medicated transdermal cream used to treat deep muscle and joint pain in a proprietary base designed to increase absorption. May also be used to treat bruising and skin irritations / inflammations (e.g. due to insect bites, psoriatic lesions) MECHANISMS OF ACTION: Analgesic (reduces pain) Antispasmodic Anti-inflammatory Anti-arthritic INGREDIENTS: Cannabis Whole Plant Extract 200mg, Proprietary Base (Distilled water, coconut oil, glycerin, stearic acid, emulsifying wax, Optiphen Plus, Arnica Montana, Salix Alba) Lavender Scent contains; Lavendula Officinalis) DOSING SUGGESTION: Apply topically, avoid open skin, use as needed. Note: topical formulations containing THC do NOT exert a psychoactive effect. CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Do not apply to damaged or broken skin. Avoid use in Pregnancy & Lactation. Discontinue this formula at least 2 weeks before a scheduled surgery. POSSIBLE SIDE EFFECTS: None reported. Page 10 of 22

13 CBD ONLY PRODUCT LINE FORMULAS Page 11 of 22

14 CBD PURE 600 mg USES: This formula uses high potency, solvent & pesticide free Cannabidiol (CBD) from the industrial hemp plant to create a safe, effective, and economical treatment option to reduce pain and the anxiety and insomnia associated with it. In addition, in higher doses may be effective for treating seizure disorders. MECHANISMS OF ACTION: Analgesic (reduces pain) Nervine (calms the nerves) Anxiolytic (reduces anxiety) Antispasmodic (reduces muscle spasms) Anti-convulsant (reduces seizure activity) Anti-psychotic (reduces the psychoactive effect of THC) INGREDIENTS: CANNABIDIOL 600 MG Cannabidiol concentrate, Kosher Vegetable Glycerin, Organic Coconut Oil, Flavoring This product contains NO THC and therefore has no psychoactive effect. DOSING SUGGESTION(S): 1 drop = 1 mg ½ dropper = 10 mg 1 full dropper = 20mg Adults: Starting dose 10 drops (10mg) under tongue. Can increase in increments of 5 drops (5mg) until you reach a dose that provides optimum symptom relief. Once you have titrated your dose to achieve optimum symptom relief, you can adjust your dose according to how you are feeling on a day-to-day basis. Hold for 60 secs then swallow. Can be dosed during the day or evening as this formula contains NO THC. For Seizure disorders (adults/minors): 1-5mg / kg of body weight of CBD Pure per day. Start on the low end and slowly titrate up. Take in divided doses (e.g. 2-3 times per day). Add 1 drop of DrBurns Pain ReLeaf to each dose for best results. (1mg of THC will improve the anti-convulsant effects of CBD) Page 12 of 22

15 CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Avoid use in Pregnancy & Lactation. Caution using this formula with other medications that are substrates of the Cytochrome P450 3A4 enzyme: e.g. Anxiolytics, Anti-depressants, Hypnotics and, many others. Doses of CBD greater than 25mg may slow the liver s clearance of these other medications. Discontinue this formula at least 2 weeks before a scheduled surgery. POSSIBLE SIDE EFFECTS: dry mouth, low blood pressure, light headedness, and drowsiness. Page 13 of 22

16 CBD PURE OPIOID RECOVERY FORMULA 600 mg USES: This formula uses high potency, solvent & pesticide free Cannabidiol (CBD) from the industrial hemp plant along with other botanicals to create a safe, effective, and economical treatment option to reduce Non-life-threatening Opioid withdrawal symptoms such as; Body aches & pains, Restlessness, Anxiety, Insomnia, Nausea This formula is intended for short term use only; use only during acute withdrawal and recovery phases. (Maximum of 45 consecutive days) For ongoing support, switch to DrBurns Pain ReLeafer (contains THC) or; DrBurns CBD Pure Pain ReLeafer (does NOT contain THC) MECHANISMS OF ACTION: Analgesic (reduces pain) Adaptogen (improves body s ability to adapt to stress, restores balance, increases energy) Sedative (promotes calm, induces sleep) Nervine (calms the nerves) Anti-Emetic (decreases nausea & vomiting) Anxiolytic (reduces anxiety) Anti-depressant (reduces depression) Increase GABA (calming neurotransmitter, muscle relaxer) Antispasmodic (reduces muscle spasms) INGREDIENTS: CANNABIDIOL 600 MG Cannabidol concentrate, Kosher Vegetable Glycerin, Organic Coconut Oil, Flavoring Proprietary Formula (Withania Somnifers, Astragulus Membranaceus, Valerian Officinalis, Avena Sativa) This product contains NO THC and therefore has no psychoactive effect. DOSING SUGGESTION(S): 1 drop = 1 mg ½ dropper = 10 mg 1 full dropper = 20mg Adults: Starting dose 10 drops (10mg) under tongue. Can increase in increments of 5 drops (5mg) until you reach a dose that provides optimum symptom relief. Once you have titrated your dose to achieve Page 14 of 22

17 optimum symptom relief, you can adjust your dose according to how you are feeling on a day-to-day basis. Hold for 60 secs then swallow. Can be dosed during the day or evening as this formula contains NO THC. CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Avoid use in Pregnancy & Lactation. Caution using this formula with other medications that are substrates of the Cytochrome P450 3A4 enzyme: e.g. Anxiolytics, Anti-depressants, Hypnotics and, many others. Doses of CBD greater than 25mg may slow the liver s clearance of these other medications. Discontinue this formula at least 2 weeks before a scheduled surgery. POSSIBLE SIDE EFFECTS: Discontinue use and consult your physician if any of the following symptoms occur: headache, excitability, uneasiness, insomnia, low blood pressure Page 15 of 22

18 CBD PURE PAIN ReLeafer 600 mg USES: This formula uses high potency, solvent & pesticide free Cannabidiol (CBD) from the industrial hemp plant along with other botanicals to create a safe, effective, and economical treatment option as an Opioid Painkiller Alternative. This formula is a non-narcotic painkiller combination working together to reduce moderate to severe pain conditions. Particularly effective for (but not limited to): osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, muscle pain (e.g. Fibromyalgia), chronic headaches, degenerative disc disease (e.g. low back pain), degenerative joint disease. MECHANISMS OF ACTION: Analgesic (relieves pain) Anti-inflammatory Anti-Arthritic Antispasmodic (reduces muscle spasms) Adaptogen (improves body s ability to adapt to stress, restores balance, increases energy) Anxiolytic (reduces anxiety) Sedative (promotes calm, induces sleep) INGREDIENTS: CANNABIDIOL 600 MG Cannabidol concentrate, Kosher Vegetable Glycerin, Organic Coconut Oil, Flavoring, Proprietary Formula (Withania Somnifers, Salix Alba) DOSING SUGGESTION(S): 1 drop = 1 mg ½ dropper = 10 mg 1 full dropper = 20mg Adults: Starting dose 10 drops (10mg) under tongue. Can increase in increments of 5 drops (5mg) until you reach a dose that provides optimum symptom relief. Once you have titrated your dose to achieve optimum symptom relief, you can adjust your dose according to how you are feeling on a day-to-day basis. Hold for 60 secs then swallow. Can be dosed during the day or evening as this formula contains NO THC. Page 16 of 22

19 CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Avoid use in Pregnancy & Lactation. Caution using this formula with other medications that are substrates of the Cytochrome P450 3A4 enzyme: e.g. Anxiolytics, Anti-depressants, Hypnotics and, many others. Doses of CBD greater than 25mg may slow the liver s clearance of these other medications. Discontinue this formula at least 2 weeks before a scheduled surgery. Use Caution if you have the following conditions: kidney disease, bleeding disorder, aspirin sensitivity POSSIBLE SIDE EFFECTS: May result in a change in bleeding time for anyone with a bleeding disorder / taking anti-coagulants have your bleeding times checked regularly while using this formula. Page 17 of 22

20 CBD PURE Migraine ReLeafer 600 MG USES: This formula uses high potency, solvent & pesticide free Cannabidiol (CBD) from the industrial hemp plant along with other botanicals to create a safe, effective, and economical treatment option for chronic migraine & headache conditions. Use this formula prophylactically (as a prevention) to reduce the frequency and intensity of chronic migraines and cluster & tension headaches. This formula may also be good for tinnitus and vertigo. MECHANISMS OF ACTION: Analgesic (relieves pain) Anxiolytic (reduces anxiety) Sedative (promotes calm, induces sleep) Anti-inflammatory Anti-spasmodic Anti-depressant INGREDIENTS: CANNABIDIOL 600 MG Cannabidiol concentrate, Kosher Vegetable Glycerin, Organic Coconut Oil, Flavoring, Proprietary Formula (Tanacetum Parthenium, Lavendula Officinalis) DOSING SUGGESTION(S): 1 drop = 1 mg ½ dropper = 10 mg 1 full dropper = 20mg Adults: Starting dose 10 drops (10mg) under tongue. Can increase in increments of 5 drops (5mg) until you reach a dose that provides optimum symptom relief. Once you have titrated your dose to achieve optimum symptom relief, you can adjust your dose according to how you are feeling on a day-to-day basis. Hold for 60 secs then swallow. Can be dosed during the day or evening as this formula contains NO THC. Page 18 of 22

21 CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Avoid use in Pregnancy & Lactation. Caution using this formula with other medications that are substrates of the Cytochrome P450 3A4 enzyme: e.g. Anxiolytics, Anti-depressants, Hypnotics and, many others. Caution using this formula with other medications that are substrates of the following Cytochrome P450 enzymes: CYP1A2, CYP2C9, CYP2C19. Some ingredients in this formula may slow the liver s clearance of these other medications. Caution using this formula with anti-coagulant medications. Do Not drive or operate dangerous machinery after taking this formula. Discontinue this formula at least 2 weeks before a scheduled surgery. Caution if you have a bleeding disorder; may increase bleeding time. POSSIBLE SIDE EFFECTS: dry mouth, low blood pressure, light headedness, and drowsiness. Other possible side effects might include upset stomach, heartburn, diarrhea, constipation, bloating, flatulence, nausea, and vomiting, nervousness, dizziness, headache, trouble sleeping, joint stiffness, tiredness, menstrual changes, rash, pounding heart, and weight gain. If you experience any of these rare side effects discontinue this formula and consult with your physician. May result in a change in bleeding time for anyone with a bleeding disorder / taking anti-coagulants have your bleeding times checked regularly while using this formula. Page 19 of 22

22 CBD PURE GI ASSIST 600 mg USES: This formula uses high potency, solvent & pesticide free Cannabidiol (CBD) from the industrial hemp plant along with other botanicals to create a safe, effective, and economical treatment option designed to reduce/resolve GI conditions such as IBS, Dyspepsia, Ulcerative Colitis, Crohn s, GERD MECHANISMS OF ACTION: Anxiolytic (reduces anxiety) Anti-depressant (reduces depression) Sedative (promotes calm, induces sleep) Analgesic (reduces pain) Nervine (calms the nerves) Anti-Emetic (decreases nausea & vomiting) Antispasmodic (reduces smooth muscle spasms) Anti-inflammatory Astringent (improves digestion, eliminates diarrhea) INGREDIENTS: CANNABIDIOL 600 MG Cannabidol concentrate,kosher Vegetable Glycerin, Organic Coconut Oil, Flavoring, Proprietary Formula (Matricaria Chamomilla, Mentha Piperita, Achillea Millefolium) This product contains NO THC and therefore has no psychoactive effect. DOSING SUGGESTION(S): 1 drop = 1 mg ½ dropper = 10 mg 1 full dropper = 20mg Adults: Starting dose 10 drops (10mg) under tongue. Can increase in increments of 5 drops (5mg) until you reach a dose that provides optimum symptom relief. Once you have titrated your dose to achieve optimum symptom relief, you can adjust your dose according to how you are feeling on a day-to-day basis. Hold for 60 secs then swallow. Can be dosed during the day or evening as this formula contains NO THC. Page 20 of 22

23 CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Avoid use in Pregnancy & Lactation. Avoid using this formula with anti-coagulant medications. Caution using this formula with other medications that are substrates of the Cytochrome P450 3A4 enzyme: e.g. Anxiolytics, Anti-depressants, Hypnotics and, many others. Caution using this formula with other medications that are substrates of the following Cytochrome P450 enzymes: CYP1A2, CYP2C9, CYP2C19. Do Not drive or operate dangerous machinery after taking this formula. Discontinue this formula at least 2 weeks before a scheduled surgery. Caution if you have a bleeding disorder; may slow blood clotting time. Caution if you have any condition that might be made worse by exposure to estrogen, may have an estrogen like effect. POSSIBLE SIDE EFFECTS: dry mouth, low blood pressure, light headedness, and drowsiness. Page 21 of 22

24 CBD PURE Muscle & Joint Ointment 200 mg USES: This formula uses high potency, solvent & pesticide free Cannabidiol (CBD) from the industrial hemp plant along with other botanicals to create a safe, effective, and economical medicated transdermal cream used to treat deep muscle and joint pain in a proprietary base designed to increase absorption. May also be used to treat bruising and skin irritations / inflammations (e.g. due to insect bites, psoriatic lesions) MECHANISMS OF ACTION: Analgesic (reduces pain) Antispasmodic Anti-inflammatory Anti-arthritic INGREDIENTS: Cannabidiol concentrate 200mg, Proprietary Base (Distilled water, coconut oil, glycerin, stearic acid, emulsifying wax, Optiphen Plus, Arnica Montana, Salix Alba) Lavender Scent contains; Lavendula Officinalis) DOSING SUGGESTION: Apply topically, avoid open skin, use as needed. This product contains NO THC and therefore has no psychoactive effect. (Regardless, THC when used transdermally is NOT psychoactive) CAUTIONS / CONTRAINDICATIONS / DRUG INTERACTIONS: Do not apply to damaged or broken skin. Avoid use in Pregnancy & Lactation. Discontinue this formula at least 2 weeks before a scheduled surgery. POSSIBLE SIDE EFFECTS: None reported. Page 22 of 22