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2 CASE REPORT Global Impact Factor (GIF) (2013) EFFICACY OF PIPPALI VARDHAMANA RASAYANA IN PROGNOSIS OF REACTIVE AIRWAY DISEASE A CASE REPORT Srikanth Sajjan 1, Guruprasad K. 2*, Ramesh B. R Lecturer, Govt. Ayurvedic Medical College, Bengaluru, Mobile Number , ID - yogeshpsajjan@rediffmail.com 2. Assistant professor, Stage III, Dept of Swasthavritta, Sri Jayendra Saraswathi Ayurveda College & Hospital, Nazarathpet, Chennai, Mobile No , punithakb@gmail.com 3. Consultant Pulmonologist, Mahaveer Jain Hospital, Bengaluru, Mobile Number , ID drramesh65@yahoo.com. Article Received on - 6 th Sept 2014 Article Revised on - 27 th Oct 2014 Article Accepted on 30 th Oct 2014 All articles published in IJAAM are peer-reviewed and can be downloaded, printed and distributed freely for non commercial purpose (see copyright notice below). (Full Text Page IJAAM This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( which permits unrestricted non commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
3 CASE REPORT EFFICACY OF PIPPALI VARDHAMANA RASAYANA IN PROGNOSIS OF REACTIVE AIRWAY DISEASE A CASE REPORT *Corresponding Author Guruprasad K. Assistant professor, Stage III, Dept of Swasthavritta, Sri Jayendra Saraswathi Ayurveda College & Hospital, Nazarathpet, Chennai, Mobile No , punithakb@gmail.com QR Code IJAAM ABSTRACT: Reactive Airway Disease (RAD) is general term for conditions involving wheezing and allergic reactions. Till date only Bronchodilators and Corticosteroids are found to be effective in treating symptomatically. Sometimes it requires continuous oxygen inhalation therapy, even though, it is more inconvenient and not the exact treatment. According to Ayurveda, this Reactive Airway Disease can be related to Pranavahasrotodrushti. In this Pranavahasrotodrushti, the commonest symptom is breathlessness or difficulty to breathe and advised different treatment modalities including Rasayana prayoga. The Vardhamana Pippali Rasayana is effective Rasayana therapy which is mentioned in the treatment of Pranavahasrotodrushti vikaras. This therapy provided relief in breathlessness and increased SPO2 (Saturation of Peripheral Oxygen) for longer duration without oxygen inhalation therapy Key Words: Reactive Airway Disease (RAD), Vardhamana Pippali Rasayana, Pranavahasrotodrushti, SPO2 INTRODUCTION Reactive Airway Disease can be used to describe as history of coughing, wheezing or shortness of breath, triggered by infection, allergy etc. [1] COPD (Chronic Obstructive Pulmonary Diseases) is the name of the group of chronic and slowly progressive respiratory disorders characterized by reduced maximal expiratory flow during forced exhalation. This excludes other causes of chronic airflow obstruction such as Cystic Fibrosis, Bronchiolitis obliterans and Bronchiectasis. Thus Reactive Airway Disease is different from Chronic Obstructive Pulmonary Diseases even though differentiation is challenging. But, generally Reactive Airway Disease is caused by different pathologies of the lungs like Fibrosis and other pathologies like Corpulmonale and RAD can be associated with COPD and Asthma. Reactive Airway Disease produces symptoms like difficulty to breathe, wheezing, allergic reactions and severe generalized weakness and requires continuous oxygen inhalation therapy, Bronchodilators and corticosteroids. The increased air pollution has resulted in the increased respiratory disorders including Reactive Airway Disease. There is no any rejuvenating (Rasayana) therapy to overcome the disease along with symptomatic treatment. In Ayurveda, the breathlessness is said to be one of the prime feature of pranavahasrotas 2. In view of restoration of the prana and rejuvenation of the Pranavahasrotas, the Vardhamana Pippali Rasayana has been recommended. Even though Tridosha are responsible for shwasa (breathlessness), it is vata which gets obstructed by Kapha and Pitta and produces shwasa roga. This is the general understanding of the disease shwasa. Pippali having Katu Madhura rasa, Madhura vipaka, Ushna veerya with vatakapha shamaka guna is advocated in different disorders like shwasa, kasa etc. Hence it is one among the Naimittika Rasayana and can be administered in shwasa roga. Vardhamana Pippali prayoga is, in which specific diseases is treated thus this is called as Vyadhihara Rasayana obviously one can get all the benefits of Rasayana therapy. It has been advocated in ascending and descending order throughout its course with cow milk for about 19 days and 10 th day being the highest dose. 3 A single case study of Reactive Airway Disease with Corpulmonale is reported here. CASE REPORT A 50 year old female patient visited Bhagwan Mahaveer Jain Hospital on with complaints of severe breathlessness since morning and swelling of both lower limbs and was diagnosed for acute exacerbation of Reactive Airway Disease and acute chronic respiratory distress on home oxygen due to Corpulmonale. It was treated as sputum negative PTB since April 2013 for 9 months at Mallya Hospital and is a known case of hypertension since 10 years. She was on home oxygen for chronic respiratory Page40
4 failure since 8 months. Patient was admitted on and discharged on after treating symptomatically with the help of Bronchodilators, corticosteroids, oxygen inhalation therapy. But patient improved only in terms of increased SPO 2 of 97% with continuous Oxygen inhalation and was not satisfied with SPO 2 of room air (drastically reducing to 70% SPO 2), generalized weakness and general enthusiasm to carry out daily personal routines like bathing etc. Considering this as Pranavahasrotodrushti, started Vardhamana Pippali Rasayana for a short term course, easily available, economical and best suited for shwasa was administered as per the reference in Susrutha Samhitha Chikithsa Sthana. RESULTS After 19 days of Rasayana therapy, patient was assessed with subjective parameters and there was satisfactory improvement in general condition and duration of breathing without oxygen supply. Even SPO 2 of 85% was seen in room air for about four hours after oxygen detachment. DISCUSSION Lakshanas which are explained in Pranavahasrotodrushti are closely associated with the features of Reactive Airway Disease. This can be considered as the nearest clinical entity for Reactive Airway Disease. Shwasa Krichrata is due to Pranavaha Sroto Sankocha, Due to Vatakara Nidanas Vata Prakopa takes place in Pranavaha Srotas and being obstructed by Kapha. Thus the vitiated Vayu causes the Pranavaha Sroto Sankocha leading to Shwasa Krichrata, Pippali by its Madhura Vipaka, Sheeta Veerya and Snigdha guna acts mainly on aggravated Vata. Pippali also has Yogavahi property therefore it helps in dilatation of Srotas. Pippali Vardhamana Rasayana has showed maximum improvement in all the subjective parameters undertaken in assessment criteria. CONCLUSION Samprapti is having major role in producing diseases but understanding the Samprapti is very difficult, as various exogenous and endogenous factors are responsible for producing Pranavaha Sroto vikara. Shwasa Krichrata is due to Pranavaha Sroto Sankocha. Due to Vatakara Nidanas Vata Prakopa takes place in Pranavaha Srotas and being obstructed by Kapha. Thus the vitiated Vayu causes the Pranavaha Sroto Sankocha leading to Shwasa Krichrata. This study shows that Pippali Vardhamana Rasayana is one of the best Naimittika Rasayana. REFERENCES 1. Harrison s principles of internal medicine, 15th edition, McGraw Hill publications, Year of Publication- 2003, p Pt. Kashinath Shastri, Charaka Samhitha, Vimana Sthana, Hindi commentary, Choukambha Sanskrit Sansthana, Varanasi, Fourth Edition, Year of Publication Chapter 5th, Shloka 7, p Priyavrata Sharma, Sushrutha Samhitha, Chikithsa Sthana, English translation, Choukambha Visvabharati, Varanasi, First Edition, Year of Publication- 2000, Chapter 5, Shloka no 12, p CITE THIS ARTICLE AS Srikanth Sajjan et.al., Efficacy of Pippali Vardhamana Rasayana in Prognosis of Reactive Airway Disease A Case Report, Int. J. Ayu. Alt. Med., 2014;2(5): Source of Support Nil Conflict of Interest None Declared Page41
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