Plant information GINSENG

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1 Plant extracts, naturally from Botanica! Botanica Industrie Nord CH- Plant information GINSENG Panax ginseng, Araliaceae Sales Author: DÖ Date: Version: 002 Plant Manfred Schütze pixelio Number: F-VKP-B02-EN Ginseng is a perennial plant growing to 1m. Ginseng has oval, toothed leaves and a cluster of small green-yellow flowers. Ginseng is native to northern China, eastern Russia, and North Korea, but is now extremely rare in the wild. Ginseng cultivation requires great skill. It is propagated from seed in spring and requires rich, moist, but well-drained soil. The plant takes at least 4 years to mature. The root is then normally harvested in autumn, washed, and steamed before being dried. Ginseng is the most famous Chinese herb of all. It has been valued for its remarkable therapeutic benefits for about 7000 years. Ingredients Triterpenoid saponins (0.7 3%), ginsenosides at least 25 have been identified, acetylenic compounds, panaxans, sesquiterpenes. Effect and applications Elasticizing Tonic Hair conditioning Literature: Patri, F., Silano, S. (2002): Plants in cosmetics Volume I. Strasbourg: Council of Europe.

2 Plant extracts, naturally from Botanica! Botanica Product specification Ginseng Bio Extract (in Glycerine / Water, not preserved (V82)) Article No. P Manufacturer, Schweiz INCI (EU + CH) Glycerin, Aqua, Panax Ginseng Root Extract INCI (US, PCPC) Glycerin, Water, Panax Ginseng Root Extract page 1, P , Ginseng Bio Extract Ratio 1 kg extract out of 0.1 kg dried material Extraction At room temperature with a circulating glycerin-water mixture Origin Purely natural, not animal Batch specific Preservation System Without preservative, pseudo preserved, therefore avoid contamination Shelf life To reevaluate after 18 months Storage Conditions In original closed packaging, cool, dry and protected from light Application Concentration 2-7 % in cosmetic formulations Note The plant material used are natural and not standardized. Hence, there are some variations between different harvests and origins - they do not injure the quality of the product. Specification Date All older specifications are no longer valid. Note Slight turbidity, sedimentation or colour changes can occur in natural products and do not injure the quality of the product. Botanica neither performs nor commissions tests on animals. Botanica does not use genetically modified raw materials. VOC-Content < 3% VOC (Volatile Organic Compounds); no VOC taxation in. The product can contain traces of ethanol from production processes or / and raw materials. Customs tariff no. (CH) Customs tariff no. (EU) Analysis Method Specification Odour Appearance Saccharide detection V-APP-D05 positiv characteristic yellowish - yellow Density 20 C [g/ml] V-APP-D Refraction index 20 C V-APP-D Solubility in Water 10% clear - slightly turbid Solubility in Alcohol 10% clear - slightly turbid Microbiology [cfu/g] PhEur <=100 * This test is done from time to time. Composition Ingredient INCI CAS EC Glycerin Aqua Panax Ginseng Root Extract Quality plant min bio/plant %-key > 50% > 10% - <= 25% > 0.1% - <= 1% Seite 1/2

3 Plant extracts, naturally from Botanica! Botanica page 2, P , Ginseng Bio Extract Natural 16 of 26 compounds according to 76/768/EC, Appendix III, Part 1, No. 45, (> 1ppm) Further compounds according to 76/768/EC, Appendix III, Part 1 No. 45, are not expected at concentrations above 1 ppm in this extract. Compounds with possible sensitizing / or other problematic side effects (> 1 ppm) Compounds Side Effect Be found in % in extract (delta-)3-carene Sensitizing Pine resin, Angelica root CAS alfa-pinene CAS Methyleugenol CAS , < 0.001% in Rinse-off < % in Leave-on Estragol CAS Safrol CAS Methoxycumarin (Herniarin), CAS Hypericin CAS Sesquiterpenlactone, (alfa-methylen-gamma- Lactonringe) Phenylacetaldehyde (Hyacinthin), CAS Glucosinolate: precursor of mustard oil Sensitizing in high concentrations Genetic toxic, carcinogenic Genetic toxic, carcinogenic Genetic toxic, carcinogenic Carcinogenic, photo sensitizing Summer Savory, Fennel, Laurel, Nutmeg, Pepper, Sage, Thyme, Juniper, Cinnamon, Orange blossom, Conifer resin Tarragon, Sweet Basil, Anise, Star Anise, Jamaica Pepper, Mace, Lemongrass, Fennel, Myrtle, Laurel, Cinnamon Tarragon, Sweet Basil, Anise, Star Anise, Oil of Bay, sweet Majoran,Pine, Jamaica Pepper, Mace, Lemongrass, Fennel, Myrtle, Laurel, Cinnamon Sassafras, Camphor, Star Anise, Laurel, Fennel, Mace German Chamomile, Flax Weed Photosensitizing St. John's Wort Sensitizing if allergic to composite family Sensitizing Mustard oil is a contact allergen, can cause skin irritations Arnica montana, Calendula, German Chamomile, Yarrow Orchids, Frangipani, African Marygold, Lilys, Lily of the Valley Caper plants, Nasturtium, Cruciferous plants, Mustard semen The information about the sensitizing substances as well as for the "Natural 16 of 26 compounds of 76/768/EC, Appendix III, Part 1, No. 45, 67-92" are based on technical literature. The information given is based on our current knowledge and experience, and may be used at customer's discretion and risk. The user of the products is solely responsible for compliance with all laws and regulations applying to the use of the products, including intellectual property rights of third parties. If raw materials of the customer are used, the information given will be non-binding. We reserve the right to make changes due to technological progress or other considerations. Seite 2/2

4 1 / 5 1. Identification of the substance/preparation and of the company/undertaking Use of the Substance/Preparation Company/Undertaking Identification Emergency telephone number 2. Hazards identification None. Cosmetic additive Tel Fax regulatory@botanica.ch (Tox Center) 3. Composition/information on ingredients Chemical characterization Solution. The product contains no substances which at their given concentration, are considered to be hazardous to health. 4. First aid measures General advice Inhalation Skin contact The product contains no substances known to be hazardous to health in concentrations which need to be taken into account. No special measures required. Wash with water and soap as a precaution.

5 2 / 5 Eye contact Ingestion 5. Fire-fighting measures Suitable extinguishing media Extinguishing media which must not be used for safety reasons Special protective equipment for firefighters 6. Accidental release measures Personal precautions Environmental precautions Methods for cleaning up Rinse thoroughly with plenty of water, also under the eyelids. If eye irritation persists, consult a specialist. Clean mouth with water and drink afterwards plenty of water. Use dry chemical, CO2, water spray or alcohol foam. High volume water jet. Standard procedure for chemical fires. No special measures required. No special environmental precautions required. Clean up promptly by sweeping or vacuum. After cleaning, flush away traces with water. 7. Handling and storage Handling Storage No special technical protective measures required. Store in original container. Keep tightly closed in a dry and cool place. 8. Exposure controls / personal protection Occupational exposure controls General industrial hygiene practice. Personal protection equipment

6 3 / 5 Respiratory protection Hand protection Eye protection 9. Physical and chemical properties Form Colour Odour Physical and chemical properties 10. Stability and reactivity Stability Conditions to avoid No special protective equipment required. Solvent-resistant gloves. Avoid contact with eyes. Liquid. Natural colour. Characteristic. ph 3-8. Flash point: > 60 C. Water solubility: soluble Density > 0.99 g/ml. No decomposition if used as directed. Vapours in contact with fire or red-hot surfaces may form decomposition products with highly irritating and warning effects. Hazardous decomposition products None under normal use. 11. Toxicological information Acute toxicity Local effects Long term toxicity Sensitization LD50/oral/rat > 2000 mg/kg. Contact with eyes may cause irritation. Negligible. Negligible.

7 4 / 5 Human experience Further information 12. Ecological information Ecotoxicity Persistence / degradability Bioaccumulative potential 13. Disposal considerations Waste from residues / unused products Contaminated packaging 14. Transport information This product has no known adverse effect on human health. Information given is based on data on the components and the toxicology of similar products. Ecological injuries are not known or expected under normal use. Taking into consideration the properties of several components, the product is estimated to be biodegradable according to OECD classification. Readily biodegradable. Does not bioaccumulate. Dispose of in accordance with local regulations. Offer rinsed packaging material to local recycling facilities. Further Information Not classified as dangerous in the meaning of transport regulations. 15. Regulatory information 16. Other information Further information Not relevant.

8 5 / 5 Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release.

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