Chemistry and Safety of Acrylamide in Food

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1 Chemistry and Safety of Acrylamide in Food Mendel Friedman Don Mottram

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3 Acrylamide in Food: The Discovery and its Implications 1 Margareta Törngvis t Acrylamide Neurotoxicity : Neurological, Morphological and Molecular Endpoints in Animal Models 2 1 Richard M. LoPachin The Role of Epidemiology in Understanding the Relationshi p Between Dietary Acrylamide and Cancer Risk i n Humans 3 9 Lorelei A. Mucci and Hans-Olov Adami Mechanisms of Acrylamide Induced Rodent Carcinogenesis 49 James E. Klaunig and Lisa M. Kamenduli s Exposure to Acrylamide 63 Barbara J. Petersen and Nga Tran Acrylamide and Glycidamide : Approach Towards Risk Assessment Based on Biomarker Guided Dosimetry of Genotoxic/Mutagenic Effects in Human Blood 77 Mathias Baum, Evelyne Fauth, Silke Fritzen, Armin Herrmann, Peter Mertes, Melanine Rudolphi, Thomas

4 Spormann, Heinrich Zankl, Gerhard Eisenbrand and Daniel Berto w Pilot Study of the Impact of Potato Chips Consumption o n Biomarkers of Acrylamide Exposure 89 Hubert W. Vesper, Hermes Licea-Perez, Tunde Myers, Maria Ospina, and Gary L. Mayer s LC/MS/MS Method for the Analysis of Acrylamide an d Glycidamide Hemoglobin Adducts 97 Maria Ospina, Hubert W. Vesper, Hermes Licea-Perez, Tunde Myers, Luchuan Mi, and Gary L. Mayers Comparison of Acrylamide Metabolism in Humans an d Rodents 109 Timothy R. Fennell and Marvin A. Friedman Kinetic and Mechanistic Data for a Human Physiologicall y Based Pharmacokinetic (PBPK) Model for Acrylamide. 117 Melvin E. Andersen, Joseph Scimeca, and Stephen S. Olin In Vitro Studies of the Influence of Certain Enzymes on th e Detoxification of Acrylamide and Glycidamide in Blood 127 Birgit Paulsson, Margareta Warholm, Agneta Rannug, an d Margareta Törngvist Biological Effects of Maillard Browning Products that Ma y Affect Acrylamide Safety in Food 135 Mendel Friedman Acrylamide: Formation in Different Foods and Potential Strategies for Reduction 157 Richard H. Stadler Mechanisms of Acrylamide Formation : Maillard-Induce d Transformations of Asparagine Blank, F. Robert, T. Goldmann, P. Pollien, N. Varga, S. Devaud, F. Saucy, T. Hyunh-Ba, and R. H. Stadler

5 Mechanistic Pathways of Formation of Acrylamide fro m Different Amino Acids 19 1 Varoujan A. Yalayan, Carolina Perez Locas, Andrze j Wronowski and John O'Brie n New Aspects on the Formation and Analysis of Acrylamide 205 Peter Schieberle, Peter Kohler and Michael Granvog l Formation of Acrylamide from Lipids 223 Stefan Ehling, Matt Hengel and Kakyuki Shibamot o Kinetic Models as a Route to Control Acrylamide Formation i n Food 235 Bronislaw L. Wedzicha, Donald S. Mottram, J. Stephen Elmore, Georgios Koutsidis and Andrew T. Dodson The Effect of Cooking on Acrylamide and its Precursors i n Potato, Wheat, and Rye 255 J. Stephen Elmore, Georgios Koutsidis, Andrew T. Dodson and Donald S. Mottram Determination of Acrylamide in Various Food Matrices Using a Single Extract; Evaluation of LC and GC Mas s Spectrometric Method 27 1 Adam Becalski, Banjamin P.-Y. Lau, David Lewis, Stephe n W. Seaman, and Wing F. Sun Some Analytical Factors Affecting Measured Levels o f Acrylamide in Food Products 285 Sune Eriksson and Patrik Karlsson Analysis of Acrylamide in Food 293 Reinhard Matissek and Marion Rater s On Line Monitoring of Acrylamide Formation 303 David J. Cook, Guy A. Channell, and Andrew J. Taylor Factors That Influence the Acrylamide Content of Heated Foods 317

6 Per Rydberg, Sune Eriksson, Eden Tareke, Patrik Karlsson, Lar Ehrenberg, and Margareta Törnqvis t Model Systems for Evaluating Factors Affecting Acrylamid e Formation in Deep Fried Foods 329 R. C. Lindsay and S. Jang Controlling Acrylamide in French Fry and Potato Chip Model s and a Mathematical Model of Acrylamide Formation 343 Yeonhwa Park, Heewon Yang, Jayne M. Storkson, Karen J. Albright, Wei Liu, Robert C. Lindsay, and Michael W. Pariza Quality Related Minimization of Acrylamide Formation - An Integrated Approach 35 7 Knut Franke, Marco Sell, and Ernst H. Reimerdes Genetic, Physiological, and Environmental Factors Affectin g Acrylamide Concentration in Fried Potato Products 37 1 Erin M. Silva and Philipp W. Simo n Acrylamide Reduction in Processed Foods 387 A. B. Hanley, C. Offen, M. Clarke, B. Ing, M. Roberts and R. Burc h Chemical Intervention Strategies for Substantial Suppression o f Acrylamide Formation in Fried Potato Products 393 Robert C. Lindsay and Sungjoon Jang Acrylamide in Japanese Processed Foods and Factors Affectin g Acrylamide Level in Potato Chips and Tea 405 Misuro Yoshida, Hiroshi Ono, Yoshimiro Chuda, Hirosh i Yada, Mayumi Ohnishi-Kameyama, Hidetak a Hobayashi, Akiko Ohara-Takada, Chie Matsura-Endo, Motoyuki Mori, Nobuyuki Hayashi, and Yuich i Yamaguch i The Formation of Acrylamide in UK Cereal Products 41 5 Peter Sadd and Colin Hamlet

7 Factors Influencing Acrylamide Formation in Gingerbread 43 1 Thomas M. Amrein, Barbara Schonbachler, Felix Escher, and Renato Amad o Effects of Consumer Food Preparation on Acrylamid e Formation 44 7 Lauren S. Jackson and Fadwa Al-Tahe r Index 467

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