Ovarian reserve New insights for clinical management

Transcription

1 Workshop organised by the Special Interest Group Reproductive Endocrinology Ovarian reserve New insights for clinical management ESHRE Campus 2008 Modena Italy 18 & 19 April 2008

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3 ESHRE Campus workshop Ovarian reserve New insights for clinical management Modena Italy 18 & 19 April 2008

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5 Course description In Reproductive Medicine there are several topics that impact greatly on patients and are of great concern for clinicians and scientists alike. Ovarian reserve and ovarian response to gonadotropin stimulation continue to be pressing examples. The main topics of the course will be the following: Definition of ovarian reserve, the clinical assessment of ovarian reserve, the role of Anti-Mullerian Hormone in reproductive medicine, the clinical relevance of ovarian reserve assessment, and therapeutic options for women with reduced ovarian reserve. The SIG Reproductive Endocrinology is offering a two-day course aimed at clinicians and researchers with an interest in the ovarian gonadal function and its manipulation. The course will attempt to analyse the current diagnostic possibilities in the evaluation of ovarian reserve. The course will also describe the current status of therapeutical approach to women with diminished ovarian reserve. Course objectives At the conclusion of this course, the participants should be able to: understand the physiology of ovarian function understand the factors influencing the ovarian reserve understand the role of AMH in regulating folliculogenesis and its diagnostic utility apply the diagnostic procedure in the evaluation of ovarian reserve know the different therapeutical approaches to women with reduced ovarian reserve Target audience Gynaecologists, reproductive endocrinologists, biologists and all those with interest in reproductive medicine

6 Scientific organisers A. Volpe (Italy) N. Macklon (The Netherlands) Scientific committee A. La Marca (Italy) S. Giulini (Italy) FACULTY & ORGANIsATION Faculty F.J. Broekmans (The Netherlands) P.G. Crosignani (Italy) A. De Pol (Italy) P. Devroey (Belgium) J. Dor (Israel) R. Fanchin (France) B. Fauser (The Netherlands) R. Felberbaum (Germany) A.R. Genazzani (Italy) L. Gianaroli (Italy) S. Giulini (Italy) A. Gougeon (France) V. Jasonni V (Italy) N. Josso (France) A. La Marca (Italy) C.B. Lambalk (The Netherlands) N. Macklon (The Netherlands) G.B. Melis (Italy)

7 Faculty S. Muttukrishna (United Kingdom) C. Nappi (Italy) F. Petraglia (Italy) J. Tapanainen (Finland) D. Toniolo (Italy) A. Veiga (Spain) J. Visser (The Netherlands) A. Volpe A (Italy) Local organising secretariat MKT Consulting Via Cassia Rome Italy Tel: Fax: info@mkt-consulting.it Organising secretariat ESHRE Central Office Meerstraat Grimbergen Belgium Tel: Fax: info@eshre.com

8 General Information Venue Aula Magna Centro Servizi Facoltà di Medicina e Chirurgia Policlinico di Modena Via del Pozzo, Modena Italy Modena Modena is located in Emilia-Romagna, a north-central region of Italy stretching over a fertile plane and flanking the Apennine Mountains. With its 200,000 inhabitants, it is both tranquil and lively, a place where modernity and tradition meet and engage comfortably with one another. You can explore Modena by having a passeggiata under the porticos overarching its sidewalks. The cobblestone streets of the historic center and the buildings amber shades give you the opportunity to relive the medieval town still filled by the echoes of the court of the Estense family. Modena is home to the twelfth-century Romanesque Cathedral declared by Unesco to be among the five hundred masterpieces of the world; the impressive rooms of the municipal palace;

9 the imposing Palazzo Ducale; the collective beauty of numerous churches. The city s artistic and historic treasures coexist in harmony with bookstores, boutiques where artists and artisans sell their goods, traditional markets, bars where you can sit and drink an aperitivo, as well as Modena s renowned restaurants and the less formal trattorias. Finally, its central geographic location allows you to reach the major cities as well as the smaller, lesser-known towns of Italy quite easily. Modena is located in quite a strategic position: it is very close and well connected with some well known cities like Milan, Venice, Verona, Florence, Bologna and other cities, maybe not as well know, but never the less beautiful and full of interesting things to see. Furthermore, it is possible to make beautiful excursions to the Apennine, the charming mountains on the border of Emilia-Romagna and Tuscany, or easily reach the Adriatic Sea in the east (Rimini, Riccione etc, famous for the most entertaining night life of Italy) or the Ligurian Sea and the Tyrrhenian Sea in the west (characterized by beautiful villages such as Cinque Terre or great beaches like the one of Versilia). For info on Modena see

10 General Information How to reach Modena? If you arrive in Italy by plane the nearest airport to Modena is the airport Marconi of Bologna (about 30 km from Modena). From Bologna you can take a bus, train or taxi to Modena. Bus There is a direct bus from the Bologna airport to Modena - price of the one-way ticket: 10. The bus leaves every 2 hours from 6:15 to 22:30. The bus stop is at the exit of the airport, international arrivals, at the bus stop ATCM (see Train There is also a bus from the airport to the train station of Bologna from where it is possible to take a train to Modena - price of the one-way ticket: about 5 without the supplementary charges (see Taxi The taxi is probably the easiest way to arrive in Modena (about 60). The other Italian airports from which it is easy to reach Modena are: Milan Linate - 30 minutes by bus to the central station of Milan + 2 hours by train to Modena. Milan Malpensa - 40 minutes by train to the central station of Milan + 2 hours by train to Modena.

11 How to reach the meeting venue? By bus Take the bus n.7 from Modena Railway Station. In minutes you will reach the University Hospital Policlinico di Modena. The Aula Magna is in the Facoltà di Medicina e Chirugia building. By taxi From the Railway station you will reach the congress venue in 10 minutes Hotel accommodation MKT Consulting Via Cassia Roma Italy Tel: Fax: info@mkt-consulting.it

12 Programme - 18 april 2008 Morning Registration Welcome and opening of the meeting A. Volpe (Italy), N. Macklon (The Netherlands) Definition of ovarian reserve Chair: A. De Pol (Italy), V. Jasonni (Italy) Fertility and reproductive ageing P.G. Crosignani (Italy) Ovarian reserve: quantity or quality J. Tapanainen (Finland) Genetic determinants of ovarian reserve D. Toniolo (Italy) Neo-oogenesis: myth or reality? A. Gougeon (France) Coffee break Assessment of ovarian reserve Chair: N. Macklon (The Netherlands), G.B. Melis (Italy) Ultrasound markers of ovarian reserve F. Broekmans (The Netherlands) Hormonal markers of ovarian reserve S. Muttukrishna (UK) Efforts to improve the reliability of ovarian reserve markers R. Fanchin (France) Lunch

13 Afternoon Antimullerian hormone: a clinical update Chair: P. Devroey (Belgium), R. Genazzani (Italy) The physiological role of AMH N. Josso (France) Circulating AMH from fetus to adulthood J. Visser (The Netherlands) AMH as a marker of ovarian dysfunction B. Fauser (The Netherlands) AMH: Clinical relevance in ART A. La Marca (Italy) Coffee break Round table - AMH: what do we still need to know? Chair: B Fauser (The Netherlands) Discussants: F. Broekmans, P. Devroey, R. Fanchin, A. Gougeon, N. Josso, A. La Marca, C. Lambalk, S. Muttukrishna, J. Tapanainen, J. Visser Aim: To formulate future research needs. Topics include: Assay standards, function in PCOS, AMH receptor SNPs

14 Programme - 19 april 2008 Morning Clinical aspects Chair: C. Nappi (Italy), F. Petraglia (Italy) Ovarian ageing and twinning C. Lambalk (The Netherlands) The ART and pregnancy outcome in patients with diminished ovarian reserve L. Gianaroli (Italy) Cost-effectiveness of infertility treatment in ageing women P. Devroey (Belgium) Preservation of fertility in women at risk for depletion of ovarian reserve J. Dor (Israel) Coffee break Options for women with diminished ovarian reserve Chair: B. Fauser (The Netherlands), A. Volpe (Italy) GnRH analogs in poor responders S. Giulini (Italy) Gonadotropin stimulation regimens N. Macklon (The Netherlands) Adjuvant therapies R. Felberbaum (Germany) Making gametes and helping embryos A.Veiga (Spain) Closing remarks A. Volpe (Italy), N. Macklon (The Netherlands)

15 Social events 18 April Workshop dinner at Villa Cesi - 18 April The dinner will be held in an ancient villa in the Modena countryside. During the dinner a musical entertainment will be provided. The dinner is optional and a fee of 100 Euro is charged. 19 April Social event at the Galleria Ferrari - 19 April On Saturday 19, at the end of the meeting, you will leave Modena and reach Maranello (20 minutes by bus) to have a lunch in the restaurant il Cavallino and to have a visit in the galleria Ferrari ( We will come back in Modena at 6 p.m. The social event is optional and a fee of 70 euro is charged.

16 Registrations For availability of places, please check first with the ESHRE Central Office. The following fees apply: 1. Members of ESHRE = 150 Euro 2. Non-members of ESHRE = 200 Euro 3. Student member of ESHRE = 70 Euro 4. Student non-member of ESHRE* = 100 Euro 5. Accompanying person = 70 Euro * Student applies to undergraduate, graduate and medical students, residents and post-doctoral research trainees. A letter from the Head of the department proving the participant s student status must accompany each student registration. Registration fees 1-4 include Attendance to all sessions Symposium syllabus Lunches Coffee breaks Certificate of attendance Registration fees 5 includes Lunches Coffee breaks Cancellation policy All cancellations should be made in writing. An administrative fee of 25 Euro will be charged for all cancellations. Cancellations received after 15 March 2008 will not be refunded.

17 MODENA, ITALY - 18 & 19 april 2008 REGISTRATION FORM - ESHRE CAMPUS PARTICIPANT S DETAILS Prof. Dr Prof. Dr. Mr Mrs Ms ESHRE member ref. n :... First name:...family name:... Department:... Institute:... Postal address:... Postcode:... City:... Country:... Telephone:... Fax: REGISTRATION (please tick the appropriate box) Members of ESHRE = 150 Euro Non-members = 200 Euro Student member of ESHRE = 70 Euro Student non-member of ESHRE = 100 Euro Accompanying persons = 70 Euro 3. SOCIAL EVENTS I will attend the social dinner at Villa Cesi on 18 April alone = 100 Euro I will attend the social dinner at Villa Cesi on 18 April with my accompanying person(s) = 100 Euro x... n of persons =... Euro I will attend the social dinner at the Galleria Ferrari on 19 April alone = 70 Euro I will attend the social dinner at the Galleria Ferrari on 19 April with my accompanying person(s) = 70 Euro x... n of persons =... Euro 4. PAYMENT (please clearly indicate the method of payment) PLEASE NOTE! The preferred methods of payment are eiter by bank transfer or credit card. Cheques and bank drafts will not be accepted. I have made a bank transfer for the amount of... Euro on ESHRE international account number (IBAN) IBAN BE BIC = GKCCBEBB (national account n ) of DEXIA Bank, Pachecolaan 44, 1000 Brussels, Belgium I would like to pay with credit card. Please complete the following information: American Express Eurocard/Mastercard Visa If private card: Name:... Initials:... If company card: Company name:... Card number:... Expiry date:... (month)... (year) Cancellations: All cancellations should be made in writing. An administrative fee of 25 Euro will be charged for all cancellations. Cancellations received after 15 March 2008 will not be refunded. Signature:...Date:... RETURN TO: ESHRE Central Office, Meerstraat 60, 1852 Grimbergen, BELGIUM Tel: Fax: info@eshre.com

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