PETER HUMAIDAN BIOGRAPHY:

Transcription

1 PETER HUMAIDAN BIOGRAPHY: Peter Humaidan is a specialist in reproductive endocrinology, professor and clinical director of the Fertility Clinic at Odense University Hospital, Denmark. He trained at the Sahlgrenska University Hospital, Gothenburg, Sweden, where he also completed a speciality degree in obstetrics and gynaecology. His research interests include reproductive endocrinology, the function of gonadotrophins, sperm chromatin integrity in relation to assisted reproduction and gonadotrophin-releasing hormone-(gnrh) antagonist co-treatment in ovarian stimulation. During recent years, his research has been focused on GnRHa triggering and prevention of ovarian hyperstimulation syndrome. He is a former board member of the Danish Fertility Society. PETER HUMAIDAN RESEARCH LIST: 1: Iliodromiti S, Lan VT, Tuong HM, Tuan PH, Humaidan P, Nelson SM. Impact of GnRH agonist triggering and intensive luteal steroid support on live-birth rates and ovarian hyperstimulation syndrome: a retrospective cohort study. J Ovarian Res Dec 26;6(1):93. doi: / PubMed PMID: ; PubMed Central PMCID: PMC : Bungum L, Franssohn F, Bungum M, Humaidan P, Giwercman A. The circadian variation in Anti- Müllerian hormone in patients with polycystic ovary syndrome differs significantly from normally ovulating women. PLoS One Sep 4;8(9):e doi: /journal.pone ecollection PubMed PMID: ; PubMed Central PMCID: PMC : Iliodromiti S, Blockeel C, Tremellen KP, Fleming R, Tournaye H, Humaidan P, Nelson SM. Consistent high clinical pregnancy rates and low ovarian hyperstimulation syndrome rates in high-risk patients after GnRH agonist triggering and modified luteal support: a retrospective multicentre study. Hum Reprod Sep;28(9): doi: /humrep/det304. Epub 2013 Jul 19. PubMed PMID: : Borgbo T, Povlsen BB, Andersen CY, Borup R, Humaidan P, Grøndahl ML. Comparison of gene expression profiles in granulosa and cumulus cells after ovulation induction with either human chorionic gonadotropin or a gonadotropin-releasing hormone agonist trigger. Fertil Steril Oct;100(4): doi: /j.fertnstert Epub 2013 Jul 12. PubMed PMID:

2 5: Karlsen K, Humaidan P, Sørensen LH, Alsbjerg B, Ravn P. Motivational interviewing: a part of the weight loss program for overweight and obese women prior to fertility treatment. Gynecol Endocrinol Sep;29(9): doi: / Epub 2013 Jul 15. PubMed PMID: : Humaidan P, Thomsen LH, Alsbjerg B. GnRHa trigger and modified luteal support with one bolus of hcg should be used with caution in extreme responder patients. Hum Reprod Sep;28(9): doi: /humrep/det287. Epub 2013 Jul 9. PubMed PMID: : Fatemi HM, Polyzos NP, van Vaerenbergh I, Bourgain C, Blockeel C, Alsbjerg B, Papanikolaou EG, Humaidan P. Early luteal phase endocrine profile is affected by the mode of triggering final oocyte maturation and the luteal phase support used in recombinant follicle-stimulating hormonegonadotropin-releasing hormone antagonist in vitro fertilization cycles. Fertil Steril Sep;100(3): doi: /j.fertnstert Epub 2013 Jun 24. PubMed PMID: : Alviggi C, Pettersson K, Longobardi S, Andersen CY, Conforti A, De Rosa P, Clarizia R, Strina I, Mollo A, De Placido G, Humaidan P. A common polymorphic allele of the LH beta-subunit gene is associated with higher exogenous FSH consumption during controlled ovarian stimulation for assisted reproductive technology. Reprod Biol Endocrinol Jun 1;11(1):51. [Epub ahead of print] PubMed PMID: ; PubMed Central PMCID: PMC : Polyzos NP, Nelson SM, Stoop D, Nwoye M, Humaidan P, Anckaert E, Devroey P, Tournaye H. Does the time interval between antimüllerian hormone serum sampling and initiation of ovarian stimulation affect its predictive ability in in vitro fertilization-intracytoplasmic sperm injection cycles with a gonadotropin-releasing hormone antagonist? A retrospective single-center study. Fertil Steril Aug;100(2): doi: /j.fertnstert Epub 2013 Apr 16. PubMed PMID: : Muñoz M, Cruz M, Humaidan P, Garrido N, Pérez-Cano I, Meseguer M. The type of GnRH analogue used during controlled ovarian stimulation influences early embryo developmental kinetics: a time-lapse study. Eur J Obstet Gynecol Reprod Biol Jun;168(2): doi: /j.ejogrb Epub 2013 Jan 22. PubMed PMID: : Kol S, Humaidan P. GnRH agonist triggering: recent developments. Reprod Biomed Online Mar;26(3): doi: /j.rbmo Epub 2012 Nov 21. Review. PubMed PMID: : Alsbjerg B, Polyzos NP, Elbaek HO, Povlsen BB, Andersen CY, Humaidan P. Increasing vaginal progesterone gel supplementation after frozen-thawed embryo transfer significantly increases the delivery rate. Reprod Biomed Online Feb;26(2): doi: /j.rbmo Epub 2012 Oct 23. PubMed PMID:

3 13: Mikkelsen AT, Madsen SA, Humaidan P. Psychological aspects of male fertility treatment. J Adv Nurs Sep;69(9): doi: /jan Epub 2012 Dec 10. PubMed PMID: : Polyzos NP, Devos M, Humaidan P, Stoop D, Ortega-Hrepich C, Devroey P, Tournaye H. Corifollitropin alfa followed by rfsh in a GnRH antagonist protocol for poor ovarian responder patients: an observational pilot study. Fertil Steril Feb;99(2): doi: /j.fertnstert Epub 2012 Oct 16. PubMed PMID: : Ingerslev HJ, Humaidan P, Andersen AN. [Fertility treatment in Denmark--development and challenges]. Ugeskr Laeger Oct 8;174(41): Danish. PubMed PMID: : Andersen AN, Ingerslev HJ, Humaidan PS. [From skepticism to acceptance of assisted reproduction]. Ugeskr Laeger Oct 8;174(41):2438. Danish. PubMed PMID: : Bergh C, Lindenberg S; Nordic Crinone Study Group. A prospective randomized multicentre study comparing vaginal progesterone gel and vaginal micronized progesterone tablets for luteal support after in vitro fertilization/intracytoplasmic sperm injection. Hum Reprod Dec;27(12): doi: /humrep/des341. Epub 2012 Sep 27. PubMed PMID: : Humaidan P, Polyzos NP. (Meta)analyze this: Systematic reviews might löse credibility. Nat Med Sep;18(9):1321. doi: /nm PubMed PMID: : Muñoz M, Cruz M, Humaidan P, Garrido N, Pérez-Cano I, Meseguer M. Dose of recombinant FSH and oestradiol concentration on day of HCG affect embryo development kinetics. Reprod Biomed Online Oct;25(4): doi: /j.rbmo Epub 2012 Jul 4. PubMed PMID: : Tomás C, Alsbjerg B, Martikainen H, Humaidan P. Pregnancy loss after frozen-embryo transfer--a comparison of three protocols. Fertil Steril Nov;98(5): doi: /j.fertnstert Epub 2012 Jul 27. PubMed PMID: : Jeppesen JV, Kristensen SG, Nielsen ME, Humaidan P, Dal Canto M, Fadini R, Schmidt KT, Ernst E, Yding Andersen C. LH-receptor gene expression in human granulosa and cumulus cells from antral and preovulatory follicles. J Clin Endocrinol Metab Aug;97(8):E doi: /jc Epub 2012 Jun 1. PubMed PMID: ; PubMed Central PMCID: PMC : Kol S, Homburg R, Alsbjerg B, Humaidan P. The gonadotropin-releasing hormone antagonist protocol--the protocol of choice for the polycystic ovary syndrome patient undergoing controlled ovarian stimulation. Acta Obstet Gynecol Scand Jun;91(6): doi: /j x. Epub 2012 Apr 30. PubMed PMID:

4 23: Alviggi C, Humaidan P, Ezcurra D. Hormonal, functional and genetic biomarkers in controlled ovarian stimulation: tools for matching patients and protocols. Reprod Biol Endocrinol Feb 6;10:9. doi: / Review. PubMed PMID: ; PubMed Central PMCID: PMC : Castillo JC, Garcia-Velasco J, Humaidan P. Empty follicle syndrome after GnRHa triggering versus hcg triggering in COS. J Assist Reprod Genet Mar;29(3): doi: /s Epub 2012 Jan 12. PubMed PMID: ; PubMed Central PMCID: PMC : Humaidan P, Papanikolaou EG, Kyrou D, Alsbjerg B, Polyzos NP, Devroey P, Fatemi HM. The luteal phase after GnRH-agonist triggering of ovulation: present and future perspectives. Reprod Biomed Online Feb;24(2): doi: /j.rbmo Epub 2011 Nov 9. Review. PubMed PMID: : Humaidan P. Agonist trigger: what is the best approach? Agonist trigger and low dose hcg. Fertil Steril Mar;97(3): doi: /j.fertnstert Epub 2011 Dec 9. PubMed PMID: : Papanikolaou EG, Humaidan P, Polyzos N, Kalantaridou S, Kol S, Benadiva C, Tournaye H, Tarlatzis B. New algorithm for OHSS prevention. Reprod Biol Endocrinol Nov 3;9:147. doi: / PubMed PMID: ; PubMed Central PMCID: PMC : Kol S, Humaidan P, Itskovitz-Eldor J. GnRH agonist ovulation trigger and hcg-based, progesterone-free luteal support: a proof of concept study. Hum Reprod Oct;26(10): doi: /humrep/der220. Epub 2011 Jul 21. PubMed PMID: : Fedder J, Erb K, Humaidan P, Maigaard S, Gabrielsen A, Pedersen B, Kaspersen MD, Loft A. Prenatal diagnostics in TESA/PESA pregnancies in Denmark : a shift from invasive procedures to nuchal translucency examination. Syst Biol Reprod Med Oct;57(5): doi: / Epub 2011 Jul 7. PubMed PMID: : Papanikolaou EG, Polyzos NP, Humaidan P, Pados G, Bosch E, Tournaye H, Tarlatzis B. Aromatase inhibitors in stimulated IVF cycles. Reprod Biol Endocrinol Jun 21;9:85. doi: / Review. PubMed PMID: ; PubMed Central PMCID: PMC : Yding Andersen C, Bungum L, Nyboe Andersen A, Humaidan P. Preovulatory progesterone concentration associates significantly to follicle number and LH concentration but not to pregnancy rate. Reprod Biomed Online Aug;23(2): doi: /j.rbmo Epub 2011 Apr 28. PubMed PMID: : Humaidan P, Westergaard LG, Mikkelsen AL, Fukuda M, Yding Andersen C. Levels of the epidermal growth factor-like peptide amphiregulin in follicular fluid reflect the mode of triggering ovulation: a comparison between gonadotrophin-releasing hormone agonist and urinary human

5 chorionic gonadotrophin. Fertil Steril May;95(6): doi: /j.fertnstert Epub 2011 Mar 5. PubMed PMID: : Papanikolaou EG, Humaidan P, Polyzos NP, Tarlatzis B. Identification of the high-risk patient for ovarian hyperstimulation syndrome. Semin Reprod Med Nov;28(6): doi: /s Epub 2010 Nov 16. Review. PubMed PMID: : Kol S, Humaidan P. LH (as HCG) and FSH surges for final oocyte maturation: sometimes it takes two to tango? Reprod Biomed Online Nov;21(5): doi: /j.rbmo Epub 2010 Jun 27. PubMed PMID: : Papanikolaou EG, Fatemi H, Camus M, Kyrou D, Polyzos NP, Humaidan P, Tarlatzis B, Devroey P, Tournaye H. Higher birth rate after recombinant hcg triggering compared with urinary-derived hcg in single-blastocyst IVF antagonist cycles: a randomized controlled trial. Fertil Steril Dec;94(7): doi: /j.fertnstert Epub 2010 Jun 26. PubMed PMID: : Humaidan P, Quartarolo J, Papanikolaou EG. Preventing ovarian hyperstimulation syndrome: guidance for the clinician. Fertil Steril Jul;94(2): doi: /j.fertnstert Epub 2010 Apr 22. Review. PubMed PMID: : Alviggi C, Humaidan P, Howles CM, Tredway D, Hillier SG. Biological versus chronological ovarian age: implications for assisted reproductive technology. Reprod Biol Endocrinol Sep 22;7:101. doi: / Review. PubMed PMID: ; PubMed Central PMCID: PMC : Bungum M, Giwercman A, Bungum L, Humaidan P, Rastkhani H, Giwercman YL. Polymorphisms in the protein C inhibitor gene in in vitro fertilization failure. Fertil Steril Jan;93(1): doi: /j.fertnstert Epub 2009 Sep 17. PubMed PMID: : Humaidan P, Ejdrup Bredkjaer H, Westergaard LG, Yding Andersen C. 1,500 IU human chorionic gonadotropin administered at oocyte retrieval rescues the luteal phase when gonadotropin-releasing hormone agonist is used for ovulation induction: a prospective, randomized, controlled study. Fertil Steril Feb;93(3): doi: /j.fertnstert Epub 2009 Feb 6. PubMed PMID: : Devroey P, Aboulghar M, Garcia-Velasco J, Griesinger G, Humaidan P, Kolibianakis E, Ledger W, Tomás C, Fauser BC. Improving the patient's experience of IVF/ICSI: a proposal for an ovarian stimulation protocol with GnRH antagonist co-treatment. Hum Reprod Apr;24(4): doi: /humrep/den468. Epub 2009 Jan 19. Review. PubMed PMID: : Alsbjerg B, Humaidan PS. [Triplet pregnancy following IVF treatment with a single embryo]. Ugeskr Laeger Aug 11;170(33):2460. Danish. PubMed PMID:

6 42: Humaidan P. Lutropin alfa: a viewpoint by Peter Humaidan. Drugs. 2008;68(11):1541. PubMed PMID: : Bungum M, Spanò M, Humaidan P, Eleuteri P, Rescia M, Giwercman A. Sperm chromatin structure assay parameters measured after density gradient centrifugation are not predictive for the outcome of ART. Hum Reprod Jan;23(1):4-10. Epub 2007 Nov 6. PubMed PMID: : Griesinger G, Kolibianakis EM, Papanikolaou EG, Diedrich K, Van Steirteghem A, Devroey P, Ejdrup Bredkjaer H, Humaidan P. Triggering of final oocyte maturation with gonadotropin-releasing hormone agonist or human chorionic gonadotropin. Live birth after frozen-thawed embryo replacement cycles. Fertil Steril Sep;88(3): Epub 2007 Apr 23. PubMed PMID: : Stener-Victorin E, Humaidan P. Use of acupuncture in female infertility and a summary of recent acupuncture studies related to embryo transfer. Acupunct Med Dec;24(4): Review. PubMed PMID: : Humaidan P, Brock K, Bungum L, Stener-Victorin E. Pain relief during oocyte retrieval--exploring the role of different frequencies of electro-acupuncture. Reprod Biomed Online Jul;13(1): PubMed PMID: : Humaidan P. Are endogenous LH levels during ovarian stimulation for IVF using GnRH analogues associated with the probability of ongoing pregnancy? A systematic review. Hum Reprod Update May-Jun;12(3):325-6; author reply Epub 2006 Mar 31. PubMed PMID: : Humaidan P. To add or not to add LH: comments on a recent commentary. Reprod Biomed Online Mar;12(3): PubMed PMID: : Bungum M, Bungum L, Humaidan P. A prospective study, using sibling oocytes, examining the effect of 30 seconds versus 90 minutes gamete co-incubation in IVF. Hum Reprod Feb;21(2): Epub 2005 Oct 20. PubMed PMID: : Humaidan P, Stener-Victorin E. Pain relief during oocyte retrieval with a new short duration electro-acupuncture technique--an alternative to conventional analgesic methods. Hum Reprod Jun;19(6): Epub 2004 Apr 22. PubMed PMID: : Humaidan PS, Agerholm I, Ingerslev HJ, Pedersen C, Gerstoft J, Andersen AN. [Artificial fertilization and HIV-positive couples--a risk-reducing treatment]. Ugeskr Laeger Nov 24;165(48): Danish. PubMed PMID: