MALE INFERTILITY & SEMEN ANALYSIS
|
|
- Vivien Parks
- 6 years ago
- Views:
Transcription
1 MALE INFERTILITY & SEMEN ANALYSIS
2 DISCLOSURE Relevant relationships with commercial entities none Potential for conflicts of interest within this presentation none Steps taken to review and mitigate potential bias N/A
3 LEARNING OBJECTIVES This lecture is designed to meet the following end-of-week learning objectives: 1. List the common causes of infertility in the male 2. Interpret LH, FSH and testosterone levels in relation to primary and secondary male hypogonadism
4 MODULE OBJECTIVES By the end of this module, you should be able to: 1. List the common causes of infertility in the male 2. Interpret LH, FSH and testosterone levels in relation to primary and secondary male hypogonadism 3. Understand the steps in spermatogenesis 4. Outline steps in collection of semen sample 5. Outline an approach to interpretation of semen analysis
5 SPERMATOZOA
6 SPERMATOGENESIS Lumen Sperm cells progress from spermatogonia spermatozoa 72d duration Immature cells start at basement membrane lumen of seminiferous tubules Basement membrane 6
7 INFERTILITY Affects 15% of couples 1 Investigate after 1y unprotected intercourse 1 50% of cases due to male factor (either alone or in combo with female factor) 2 Overall, affects 7% of men Medical pathology found in only 6% of infertile men 3 1) Thonneau, P. et al. Hum. Reprod. 6, (1991). 2) (2010). 3) Kolettis, P. N. & Sabanegh, e. S. Significant medical pathology discovered during a male infertility evaluation. J. Urol. 166, (2001).
8 SEMEN ANALYSIS Most important test in evaluation of male factor infertility Need at least 2 samples over a period of a few months Preceded by 2-7d of abstinence from ejaculation Sperm density can increase by 25% per day of abstinence up to 4 days! 1 1) Carlsen, e., Petersen, J. H., Andersson, A. M. & Skakkebaek, N. Fertil. Steril. 82, (2004).
9 STEPS IN SEMEN ANALYSIS
10 WHY NEED 2 OR MORE SEMEN ANALYSES? Sperm count / concentration are highly variable day-to-day Image courtesy of Dr. J. Bain
11 SEMEN ANALYSIS IN DETAIL Many parameters reported in semen analysis Which are most important to know? 1. Semen volume 2. Sperm count and concentration 3. Sperm motility 4. Sperm morphology
12 WHAT ARE NORMAL SEMEN PARAMETERS Parameter Normal Value Semen volume 1.5mL Sperm concentration 15 million/ml Sperm count 39 million per ejaculate Sperm motility 40% Sperm morphology 4% normal forms (by strict criteria) Motility most closely correlated with pregnancy outcome! Adapted from: Hwang, K. et al. Nat. Rev. Urol. 8, 86 94
13 SEMEN ANALYSIS EXAMPLE
14 IN DETAIL: CONCENTRATION Normal: 15 million/ml Oligospermia: < 15 million/ml Severe oligospermia: < 5 million/ml Azoospermia: 0 Consider genetic contributor!
15 KLINEFELTER S SYNDROME: AZOOSPERMIA
16 IN DETAIL: MORPHOLOGY Recall: normal morphology is >4% normal forms by strict criteria
17 IN DETAIL: MOTILITY Motility: amount of sperm that are swimming, or moving normal >40% Progressive motility: amount of sperm that are moving forward Twitching, or moving in circles doesn t count normal >32%
18 DIFFERENTIAL DIAGNOSIS: ABNORMAL SEMEN ANALYSIS Abnormal Semen Analysis Impaired Production Idiopathic 40-50% Obstruction 10-20% Primary Hypogonadism 30-40% Secondary Hypogonadism 1-2% 18
19 CAUSES OF MALE HYPOGONADISM 1. Primary (Hypergonadotropic hypogonadism) Testicular insult High LH, FSH Low T 2. Secondary (Hypogonadotropic hypogonadism) Hypothalamic or pituitary insult Low LH, FSH Low T 19
20 PRIMARY HYPOGONADISM (TESTICULAR INSULT) Congenital Klinefelter s Syndrome*, undescended testes Infectious Trauma Drugs mumps orchitis physical, radiation chemotherapy Infiltration hemochromatosis (Iron deposition disorder) Idiopathic 20
21 SECONDARY/TERTIARY HYPOGONADISM Neoplasia Pituitary/hypothalamic lesion Congenital Kallman s Syndrome Trauma TBI, radiation Drugs Opiates Infiltration hemochromatosis Anorexia Idiopathic Hyperprolactinemia 21
22 QUESTION 1 Spermatogenesis is characterized by a sequential series of steps. Which one of the following is correct? A. The process takes one month B. Spermatozoa arise from Sertoli cells C. As spermatozoa develop, they migrate from basement membrane to lumen D. Flagellated sperm cells are termed spermatocytes
23 QUESTION 2 Hypogonadism can be primary or secondary. Which of the following is always a secondary cause of hypogonadism? A. Prolactin excess B. Mumps C. Chemotherapy D. Trauma
Clinical evaluation of infertility
Clinical evaluation of infertility DR. FARIBA KHANIPOUYANI OBSTETRICIAN & GYNECOLOGIST PRENATOLOGIST Definition: inability to achieve conception despite one year of frequent unprotected intercourse. Male
More informationMale History, Clinical Examination and Testing
Male History, Clinical Examination and Testing Dirk Vanderschueren, MD, PhD Case Jan is 29 years old and consults for 1 year primary subfertility partner 28 years old and normal gynaecological investigation
More informationMale factors can be identified as the cause of infertility in 30~40% of couples and a
Focused Issue of This Month Causes and Diagnosis of Male Infertility Nam Cheol Park, MD Department of Urology, Pusan National University College of Medicine Email : pnc@pusan.ac.kr J Korean Med Assoc 2007;
More informationWhat You Need to Know
UW MEDICINE PATIENT EDUCATION What You Need to Know Facts about male infertility This handout explains what causes male infertility, how it is diagnosed, and possible treatments. Infertility is defined
More informationBIOCHEMICAL TESTS FOR THE INVESTIGATION OF COMMON ENDOCRINE PROBLEMS IN THE MALE
Authoriser: Moya O Doherty Page 1 of 7 BIOCHEMICAL TESTS FOR THE INVESTIGATION OF COMMON ENDOCRINE PROBLEMS IN THE MALE The purpose of this protocol is to describe common tests used for the investigation
More informationMale Factor Infertility
Male Factor Infertility Simplified Evaluaon and Treatment* ^ * In 20 minutes or less In 20 slides ^ 5 minute office visit ALWAYS EVALUATE THE MALE & THE FEMALE Why 1. To help the coupleachieve a pregnancy
More information15% ART accounts for ~4% of Australian births
The General Practice Education Day HealthEd / Generation Next 20 th February Sydney Declarations Male Infertility & Assisted Reproduction Prof Robert I McLachlan FRACP, Ph.D. Consultant Andrologist, Monash
More information15% ART accounts for ~4% of Australian births
The General Practice Education Day HealthEd / Generation Next 5 th March Melbourne Declarations Male Infertility & Assisted Reproduction Prof Robert I McLachlan FRACP, Ph.D. Consultant Andrologist, Monash
More informationAromatase Inhibitors in Male Infertility:
Aromatase Inhibitors in Male Infertility: The hype of hypogonadism? BEATRIZ UGALDE, PHARM.D. H-E-B/UNIVERSITY OF TEXAS COMMUNITY PHARMACY PGY1 03 NOVEMBER 2017 PHARMACOTHERAPY ROUNDS Disclosures No conflicts
More informationREAPPRAISAL OF THE VALUE OF TESTICULAR BIOPSY IN THE INVESTIGATION OF INFERTILITY
FERTWTY AND STEIuLlTY Copyright 1980 The American Fertility Society Vol., No.1 January 1980 Prinwl in U.S.A. REAPPRAISAL OF THE VALUE OF TESTICULAR BIOPSY IN THE INVESTIGATION OF INFERTILITY TERENCE
More informationAbnormalities of Spermatogenesis
Abnormalities of Spermatogenesis Male Factor 40% of the cause for infertility Sperm is constantly produced by the germinal epithelium of the testicle Sperm generation time 73 days Sperm production is thermoregulated
More informationMale Reproductive Physiology
Male Reproductive Physiology Overview Anatomy Function Endocrine and spermatogenesis Testis epididymus,vas deferens,seminal vesicles and prostate Hypothalamic pituitary testicular axis Hormones of the
More informationInfertility. Dafydd Ywain & Kayleigh Hansen
Infertility Dafydd Ywain & Kayleigh Hansen Terminology Epidemiology Aetiology Male infertility Female infertility Conclusion Content Terminology Fecundability The probability of conceiving during a single
More informationMale reproductive physiology
START Lecture Series Crown Conference Centre, Melbourne Feb 18 th 2017 Male reproductive physiology Prof Robert I McLachlan FRACP, Ph.D., AM Director, Clinical Research, Hudson Institute Consultant Andrologist,
More informationGUIDELINES FOR THE INVESTIGATION AND TREATMENT OF MALE INFERTILITY
GUIDELINES FOR THE INVESTIGATION AND TREATMENT OF MALE INFERTILITY G.R. Dohle, Z. Kopa, A. Jungwirth, T.B. Hargreave. Eur Urol 2002;42(4):313-322 Eur Urol 2004;46(5):555-558 Definition Infertility is the
More informationGUIDELINES ON THE INVESTIGATION AND TREATMENT OF MALE INFERTILITY
GUIDELINES ON THE INVESTIGATION AND TREATMENT OF MALE INFERTILITY G. Dohle (chairman), A. Jungwirth and W. Weidner. Eur Urol 2002;42(4):313-322 Eur Urol 2004;46(5):555-558 1. Introduction Infertility is
More informationIndex. urologic.theclinics.com. Note: Page numbers of article titles are in boldface type.
Note: Page numbers of article titles are in boldface type. A Acquired hypogonadism, prevalence of, 165 167 primary, 165 secondary, 167 Adipose tissue, as an organ, 240 241 Adrenal hyperplasia, congenital,
More information15% ART accounts for ~4% of Australian births
The General Practice Education Day HealthEd / Generation Next 23 rd July Brisbane Declarations Male Infertility & Assisted Reproduction Equity interest in Monash IVF Group Prof Robert I McLachlan FRACP,
More informationTESE: Testis Sperm Extraction
TESE: Testis Sperm Extraction Robert D. Oates, M.D., F.A.C.S. Department of Urology Boston University School of Medicine When is Microsurgical TESE indicated? Cases of Non-obstructive Azoospermia (NOA)
More informationMEN S HEALTH AFTER CANCER WHAT YOU NEED TO KNOW: INFERTILITY
UW MEDICINE TITLE OR EVENT MEN S HEALTH AFTER CANCER WHAT YOU NEED TO KNOW: INFERTILITY KEVIN A. OSTROWSKI, MD OSTROWSK@UW.EDU TOM WALSH, MD WALSHT@UW.EDU LEARNING OBJECTIVES At the conclusion of this
More informationDEFINITION HX & PH/EX
DEFINITION HX & PH/EX Because of the success of the assisted reproductive techniques (ART), the evaluation of the man is often ignored. The physician should not forget the fact that many causes of male
More informationSubfertility B Y A L I S O N, B E N A N D J O H N
Subfertility B Y A L I S O N, B E N A N D J O H N Contents Definition Causes Male Female Hx & Ex Investigations Treatment Definition Failure to conceive after a year of frequent, unprotected communion.
More informationHd Hydroxylase. Cholesterol. 17-OH Pregnenolne DHEA Andrstendiol. Pregnenolone. 17-OH Progestrone. Androstendione. Progestrone.
PATHOPHISIOLOGY OF SEX HORMONES R. Mohammadi Biochemist (Ph.D.) Faculty member of Medical Faculty CHOLESTEROL IS THE PRECURSOR OF STERIOD HORMONES Cholesterol Pregnenolone 17-OH 17βHSD Pregnenolne DHEA
More informationMale Reproduction Organs. 1. Testes 2. Epididymis 3. Vas deferens 4. Urethra 5. Penis 6. Prostate 7. Seminal vesicles 8. Bulbourethral glands
Outline Terminology Human Reproduction Biol 105 Lecture Packet 21 Chapter 17 I. Male Reproduction A. Reproductive organs B. Sperm development II. Female Reproduction A. Reproductive organs B. Egg development
More informationReversible Conditions Organising More Information semen analysis Male Infertility at Melbourne IVF Fertility Preservation
Male Infertility Understanding fertility in men Conceiving a baby depends on a number of factors, including healthy sperm. After a woman s age, this can be the biggest issue. Reproduction, although simple
More informationChris Davies & Greg Handley
Chris Davies & Greg Handley Contents Definition Epidemiology Aetiology Conditions for pregnancy Female Infertility Male Infertility Shared infertility Treatment Definition Failure of a couple to conceive
More informationTestosterone Therapy-Male Infertility
Testosterone Therapy-Male Infertility Testosterone Therapy-Male Infertility Many men are prescribed testosterone for a variety of reasons. Low testosterone levels (Low T) with no symptoms, general symptoms
More informationMale reproduction. Cross section of Human Testis ผศ.ดร.พญ.ส ว ฒณ ค ปต ว ฒ ภาคว ชาสร รว ทยา คณะแพทยศาสตร ศ ร ราชพยาบาล 1. Aims
Aims Male reproduction Male reproductive structure Spermatogenesis ส ว ฒณ ค ปต ว ฒ ห อง 216 โทร: 7578 Hypothalamo-pituitary-testicular axis Male sex hormone action Male reproductive structure Male reproductive
More informationWith advances in assisted reproduction techniques,
Journal of Andrology, Vol. 26, No. 6, November/December 2005 Copyright American Society of Andrology Clomiphene Administration for Cases of Nonobstructive Azoospermia: A Multicenter Study ALAYMAN HUSSEIN,*
More informationTESTOSTERONE DEFINITION
DEFINITION A hormone that is a hydroxyl steroid ketone (C19H28O2) produced especially by the testes or made synthetically and that is responsible for inducing and maintaining male secondary sex characteristics.
More informationLaboratory Investigation of Male Gonadal Function. Dr N Oosthuizen Dept of Chemical Pathology UP 2010
Laboratory Investigation of Male Gonadal Function Dr N Oosthuizen Dept of Chemical Pathology UP 2010 1 Figure 1. Hypothalamic-pituitary pituitary-testicular testicular axis 2 Testosterone (T) measurement
More informationAdapted from Preg. & Part., Senger
MALE ENDOCRINOLOGY AND SPERMATOGENESIS (Chapter 10) AVS 222 (Instructor: Dr. Amin Ahmadzadeh) I. MALE ENDOCRINOLOGY (Figure10-1 to 10-3) A. Glands and their respective hormones 1) Hypothalamic hormone:
More informationSeminal fluid analysis
What is semen? Semen is the fluid formed at ejaculation. Made of secretions of all the accessory glands of the male genital tract and testicular sperm component Semen quality is maintained by all the accessory
More informationTreatment of Oligospermia with Large Doses of Human Chorionic Gonadotropin
Treatment of Oligospermia with Large Doses of Human Chorionic Gonadotropin A Preliminary Report S. J. GLASS, M.D., and H. M. HOLLAND, M.D. BEFORE discussing gonadotropic therapy of oligospermia, it is
More informationMale fertility disorders
Male fertility disorders Etiology diagnosis therapeutic approaches Dr. Cornelia Roggenbuck September 29, 2009 Orthomol pharmazeutische Vertriebs GmbH Content Fertility Facts and figures Factors of influence
More informationSpontaneous Pregnancy Outcome after Surgical Repair of Clinically Palpable Varicocele in Young Men with Abnormal Semen Analysis
African Journal of Urology 1110-5704 Vol. 17, No. 4, 2011 115-121 Original article Spontaneous Pregnancy Outcome after Surgical Repair of Clinically Palpable Varicocele in Young Men with Abnormal Semen
More informationTestosterone Treatment: Myths Vs Reality. Fadi Al-Khayer, M.D, F.A.C.E
Testosterone Treatment: Myths Vs Reality Fadi Al-Khayer, M.D, F.A.C.E The Biological Functions of Testosterone in Men Testosterone is essential to the musculoskeletal and metabolic systems throughout a
More informationInformation Sheet. Male Infertility
Infertility National Public Awareness Campaign Information Sheet Male Infertility In approximately half of couples complaining of infertility part of the problem lies with the male. Male infertility has
More informationOutline. Male Reproductive System Testes and Sperm Hormonal Regulation
Outline Male Reproductive System Testes and Sperm Hormonal Regulation Female Reproductive System Genital Tract Hormonal Levels Uterine Cycle Fertilization and Pregnancy Control of Reproduction Infertility
More informationTreatment of Defective Spermatogenesis tvith Human Gonadotropins
Treatment of Defective Spermatogenesis tvith Human Gonadotropins W. Z. POLISHUK, M.D., Z. PALTI, M.D., and A. LAUFER, M.D. TREATMENT of male sterility due to defective spermatogenesis is not satisfactory.
More informationThi-Qar University - College of medicine. Department of obstetrics and gynecology DONE BY SAMI BASSAM HASSAN RAMADAN ANAS TAWFIQ
Distributional Study of Infertile Male Causes According to semen fluid analysis In a sample attend infertility center in AL- Hussein teaching hospital in Al-Nasiriyah Thi-Qar University - College of medicine
More informationCell Divisions. The autosomes represent the whole body. * Male Sex Chromosomes: XY * Female Sex Chromosomes: XX
Cell Divisions Each Cell (including gonads) has 46 chromosomes (23 pairs of chromosomes: 22 pairs of autosomes, 1 pair of sex chromosomes) which are located in the nucleus). The autosomes represent the
More informationInfertility. Rhian Allen & David Rogers.
Infertility Rhian Allen & David Rogers http://www.worldofsurrogacy.com Objectives Definition & Epidemiology Female Gonadal Axis Normal Menstrual Cycle Causes Patient History Patient Examination Investigations
More informationCLOMIPHENE THERAPY IN MALE INFERTILITY: A NEGATIVE REPORT"
FERTILITY AND STERILITY Copyright 1979 The American Fertility Society VoL 32, No.5, November 1979 Printed in U.8A. CLOMIPHENE THERAPY IN MALE INFERTILITY: A NEGATIVE REPORT" CHARLES W. CHARNY, M.D.t Department
More informationGPVTS TEACHING APRIL 2016 FERTILITY
GPVTS TEACHING APRIL 2016 FERTILITY Djavid Alleemudder - Consultant Obstetrics & Gynaecology DEFINITIONS What is the definition of infertility? Failure to conceive after 12 months despite regular, unprotected
More informationMedical Affairs Policy
Medical Affairs Policy Service: Infertility and Recurrent Pregnancy Loss Testing and Treatment PUM 250-0018-1706 Medical Policy Committee Approval 06/16/17 Effective Date 10/01/17 Prior Authorization Needed
More informationTesticular histology and gonadotropin levels in infertile men with non-obstructive oligo-/azoospermia
1 THE NATIONAL MEDICAL JOURNAL OF INDIA VOL., NO.5 Testicular histology and gonadotropin levels in infertile men with non-obstructive oligo-/azoospermia ARUN KUMAR, B. JAYAKUMAR, M. L. KHURANA, VED PRAKASH,
More informationImmune response in obstructive male infertility. Prof. A.K.Sarda Department of Surgery Maulana Azad Medical College New Delhi
Immune response in obstructive male infertility Prof. A.K.Sarda Department of Surgery Maulana Azad Medical College New Delhi Sperm transport from the testicle Seminiferous tubule contractions of the myoid
More informationMale infertility too often ignored & forgotten
Male infertility too often ignored & forgotten The journey 1. of the men A review of the guidelines Joo Teoh FRANZCOG MRCP(Ire) MRCOG MBBCh MSc(Lon) MD(Glasgow) SubspecialtyRepromed(UK) Consultant Obstetrician
More information5/5/2010. Infertility FINANCIAL DISCLOSURE. Infertility Definition. Objectives. Normal Human Fertility. Normal Menstrual Cycle
Infertility FINANCIAL DISCLOSURE I HAVE NO FINANCIAL INTEREST IN ANY OF THE PRODUCTS MENTIONED IN MY PRESENTATION Bryan K. Rone, M.D. University of Kentucky Obstetrics and Gynecology I AM RECEIVING COMPENSATION
More informationProf. Dr. Michael Zitzmann Internal Medicine Endocrinology, Diabetology, Andrology University of Muenster, Germany
Induction of fertility in hypogonadal men Prof. Dr. Michael Zitzmann Internal Medicine Endocrinology, Diabetology, Andrology University of Muenster, Germany Induction of fertility in hypogonadal men Prof.
More informationFailure to Launch. Impairment of Primary Spermatogenesis & Optimization of Reproductive Techniques
Failure to Launch. Impairment of Primary Spermatogenesis & Optimization of Reproductive Techniques October 16, 2013 Ryan Flannigan PGY3 UBC Urology http://www.chinahearsay.com/china-lethargic-sperm-economic-development/
More informationENVIRONMENTAL AND LIFE STYLE DETERMINANTS OF SEMEN QUALITY. Jorma Toppari Departments of Physiology and Pediatrics University of Turku
ENVIRONMENTAL AND LIFE STYLE DETERMINANTS OF SEMEN QUALITY Jorma Toppari Departments of Physiology and Pediatrics University of Turku 2013 Disclosures I have received lecture honoraria from Eli Lilly,
More informationSexual dysfunction of chronic kidney disease. Razieh salehian.md psychiatrist
Sexual dysfunction of chronic kidney disease Razieh salehian.md psychiatrist Disturbances in sexual function are a common feature of chronic renal failure. Sexual dysfunction is inversely associated with
More informationThe assessment and investigation of the infertile couple
The assessment and investigation of the infertile couple BIRUTE ZILAITIENE, MD, PHD, PROF., FECSM DEPARTMENT OF ENDOCRINOLOGY AND INSTITUTE OF ENDOCRINOLOGY, LITHUANIAN UNIVERSITY OF HEALTH SCIENCES, KAUNAS,
More informationdescribe the parts and function of semen and the glands that contribute to it
You need to be able to: describe spermatogenesis (How is sperm made?) describe the anatomy of a sperm describe the parts and function of semen and the glands that contribute to it How is sperm made? Spermatogenesis
More informationANDROGEN DEFICIENCY/MALE HYPOGONADISM
ANDROGEN DEFICIENCY/MALE HYPOGONADISM 1. Medical Condition Hypogonadism in men is a clinical syndrome that results from failure of the testes to produce physiological levels of testosterone (androgen deficiency)
More informationReproduction. Liang Huawei( 梁华为 )
Reproduction Liang Huawei( 梁华为 ) E-mail: liang.huawei@yahoo.com.cn Reproduction Reproduction is the biological process by which new individual organisms are produced. An individual does not need the system
More informationSperm retrieval from patients with nonmosaic Klinefelter s syndrome by semen cytology examination
Sperm retrieval from patients with nonmosaic Klinefelter s syndrome by semen cytology examination Y.-T. Jiang 1, Y. Dong 1, X.-W. Yu 1, R.-C. Du 1,2, L.-L. Li 1,2, H.-G. Zhang 1 and R.-Z. Liu 1 1 Center
More informationInfertility: failure to conceive within one year of unprotected regular sexual intercourse. Primary secondary
Subfertility Infertility: failure to conceive within one year of unprotected regular sexual intercourse. Primary secondary Infertility affects about 15 % of couples. age of the female. Other factors that
More informationAl-Anbar Medical Journal
Clinical Patterns and Major Causes of Male Infertility In Fallujah City Ziad H. Abd FIBMS(Urology) College of Medicine, University of Anbar Qais Abdul-Rahman Thamer FIBMS(Urology) College of Medicine,
More informationInfertility for the Primary Care Provider
Infertility for the Primary Care Provider David A. Forstein, DO FACOOG Clinical Associate Professor Obstetrics and Gynecology University of South Carolina School of Medicine Greenville Disclosure I have
More informationANDROGEN DEFICIENCY/MALE HYPOGONADISM
Medical Information to Support the Decisions of TUE Committees 1. Medical Condition Hypogonadism in men is a clinical syndrome that results from failure of the testes to produce physiological levels of
More informationWhy Reproduce? In order to ensure the continuation of the species and the continuation of life in general by producing offspring
HUMAN REPRODUCTION Why Reproduce? In order to ensure the continuation of the species and the continuation of life in general by producing offspring Asexual vs Sexual Reproduction Remember: Asexual reproduction:
More informationThe effects of cancer treatment on male infertility
The effects of cancer treatment on male infertility Kirsi Jahnukainen Children s Hospital, Helsinki Karolinska Institutet, Stockholm Department of Pediatrics 21.11.2017 1 Disclosure statement I declare
More informationPhysiologic Anatomy of the Male Sexual Organs
Reproductive and Hormonal Functions of the Male The reproductive functions of the male can be divided into three major subdivisions: (1) spermatogenesis, which means simply the formation of sperm; (2)
More informationDeterioration Of Sperm Morphology In Men Exposed To High Temperature
107 J Anat. Soc. India 50(2) 107-111 (2001) Deterioration Of Sperm Morphology In Men Exposed To High Temperature Dada, R.; *Gupta, N.P., Kucheria, K. Department of Anatomy & *Urology, All India Institute
More informationMale Fertility: Your Questions Answered
Male Fertility: Your Questions Answered Michael S. Neal Scientific Director, ONE Fertility, 3210 Harvester Rd. Burlington, Ontario www.onefertility.com mneal@onefertility.com Outline Assisted Conception
More information5 15/3/2012. Malik Al-Momani
5 15/3/2012 Malik Al-Momani بسم هللا الرحمن الرحيم Spermatogenesis Note : Please refer to slides so see photos. Quick Revision : - Testis is divided by septum into testicular lobules, inside the lobules
More informationThe understanding about infertility in different regions of the world is different. It varies from
The Professional Medical Journal DOI: 10.29309/TPMJ/18.4478 1. MBBS, M.Phil (Chemical Pathology) Professor, Chemical Section, Continental Medical College Lahore. 2. MBBS, M.Phil (Microbiology) Assistant
More informationGENETIC TESTING: IN WHOM AND WHEN
GENETIC TESTING: IN WHOM AND WHEN Robert D Oates, M.D. Boston University School of Medicine My background in this field I was the first to link Cystic Fibrosis Mutations with Congenital Absence of the
More informationWhat to do about infertility?
What to do about infertility? Dr. M.A. Fischer Section Head, Division of Urology, Department of Surgery Assistant Clinical Professor, Department of Obstetrics and Gynecology Hamilton Health Sciences, Hamilton,
More informationMULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.
MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question. 1) Which of the following hormones controls the release of anterior pituitary gonadotropins? A) LH
More informationProspective study to evaluate the risk factors associated with male infertility at tertiary care centre
International Surgery Journal Alam J et al. Int Surg J. 2018 Aug;5(8):2862-2868 http://www.ijsurgery.com pissn 2349-3305 eissn 2349-2902 Original Research Article DOI: http://dx.doi.org/10.18203/2349-2902.isj20183205
More informationSperm production. Sperm production. Meiosis. Mitosis. The cells of Leydig in testes secrete
Sperm production Ductus deferens Epididymis The cells of Leydig in testes secrete Seminiferous testosterone (T) tubules T secreted at puberty produces 2 o sex characteristics, spermatogenesis, & maintain
More informationSperm production. Sperm production. Controlling sperm production. Meiosis. Mitosis. The cells of Leydig in testes secrete
Ductus deferens Sperm production Epididymis The cells of Leydig in testes secrete Seminiferous testosterone (T) tubules T secreted at puberty produces 2 o sex characteristics, spermatogenesis, & maintain
More informationTo General Embryology Dr: Azza Zaki
Introduction To General Embryology The Human Development is a continuous process that begins when an ovum from a female is fertilized by a sperm from a male. Cell division, growth and differentiation transform
More informationWisam S. Najam. Dept. of Medicine, College of Medicine, Tikrit University.
Significant value of hormonal assays as a marker for Male Infertility in Tikrit city. Wisam S. Najam. Dept. of Medicine, College of Medicine, Tikrit University. Abstract Background: Infertility is defined
More informationSERUM TOTAL TESTOSTERONE AND INHIBIN B ARE THE BETTER MARKERS OF SPERMATOGENESIS THAN ANTI-MULLERIAN HORMONE IN OLIGOSPERMIC MEN
SERUM TOTAL TESTOSTERONE AND INHIBIN B ARE THE BETTER MARKERS OF SPERMATOGENESIS THAN ANTI-MULLERIAN HORMONE IN OLIGOSPERMIC MEN 1 Basil O Saleh, 2 Nawal Khairy AL-Ani and 3 Widad Hamel Khraibet 1 Department
More informationReproductive physiology. About this Chapter. Case introduction. The brain directs reproduction 2010/6/29. The Male Reproductive System
Section Ⅻ Reproductive physiology Ming-jie Wang E-Mail: mjwang@shmu.edu.cn About this Chapter The reproductive organs and how they work the major endocrine functions of sexual glands actions of sex hormones
More informationPhysiology of Male Reproductive System
Physiology of Male Reproductive System the anterior pituitary gland serves as the primary control of reproductive function at puberty Ant Pituitary secretes FSH & large amounts of LH (ICSH) FSH & LH cause
More informationHypogonadism 4/27/2018. Male Hypogonadism -- Definition. Epidemiology. Objectives HYPOGONADISM. Men with Hypogonadism. 95% untreated.
Male Hypogonadism -- Definition - Low T, Low Testosterone Hypogonadism -...a clinical syndrome that results from failure of the testes to produce physiological concentrations of testosterone due to pathology
More informationUse of Testicular Sperm for ICSI in Non-Azoospermic Men: How Far Should we Go?
Use of Testicular Sperm for ICSI in Non-Azoospermic Men: How Far Should we Go? Armand Zini, MD, FRCSC McGill University Disclosure: Shareholder in YAD Tech Neutraceuticals Co. Sperm Retrieval: Overview
More informationTestosterone Therapy in Men with Hypogonadism
Testosterone Therapy in Men with Hypogonadism (Endocrine Society 2018 Guideline) Ngwe Yin, MD Assistant Clinical Professor of Medicine, UCSF Fresno Medical Education Program Disclosures None Objective
More informationStudy on semen analysis in the evaluation of male infertility in coastal Karnataka, India
International Journal of Reproduction, Contraception, Obstetrics and Gynecology Ganiga P et al. Int J Reprod Contracept Obstet Gynecol. 2018 Jul;7(7):2603-2607 www.ijrcog.org DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20182412
More informationOBJECTIVES. Rebecca McEachern, MD. Puberty: Too early, Too Late or Just Right? Special Acknowledgements. Maryann Johnson M.Ed.
1 Puberty: Too early, Too Late or Just Right? Maryann Johnson M.Ed., BSN, RN Special Acknowledgements Rebecca McEachern, MD OBJECTIVES Illustrate basic endocrine system and hormonal pathways Define the
More informationInfertility is not an uncommon problem in Western
Review Article A Practical Approach to Testicular Biopsy Interpretation for Male Infertility Lisa A. Cerilli, MD; Wayne Kuang, MD; David Rogers, MD Infertility is not an uncommon problem in Western societies
More informationMale factors determining the outcome of intracytoplasmic sperm injection with epididymal and testicular spermatozoa
andrologia 35, 220 226 (2003) Accepted: April 25, 2003 Male factors determining the outcome of intracytoplasmic sperm injection with epididymal and testicular spermatozoa J. U. Schwarzer, K. Fiedler, I.
More informationDiseases / conditions affecting the steroid profile in blood
Athlete Biological Passport Symposion Rome, Nov. 5 7, 2018 Diseases / conditions affecting the steroid profile in blood Eberhard Nieschlag Centre of Reproductive Medicine & Andrology University Hospital
More informationSurgical Sperm Retrieval
Saint Mary s Hospital Department of Reproductive Medicine Information for Patients Surgical Sperm Retrieval About one man in a hundred produces no sperm (10-15% of all sub fertile men) - a condition known
More informationReproductive System Purpose General Structures Male Structures Functions Female Anatomy Structures Functions Clinical Applications
The Reproductive System: Male, Ch 23 Outline of class lecture After studying the male reproductive system you should be able to: 1. Define the purpose of reproduction and identify the general organs of
More informationPostgraduate Training in Reproductive Health
SURGICAL TREATMENT OF MALE INFERTILITY Georges A. de Boccard, M.D. Consultant Urologist F.M.H., F.E.B.U. Postgraduate Training in Reproductive Health Geneva Foundation for Medical Education and Research
More informationComparison of the effectiveness of placebo and a-blocker therapy for the treatment of idiopathic oligozoospermia *
FERTILITY AND STERILITY Copyright c 1995 American Society for Reproductive Medicine Printed on acid-free paper in U. S. A. Comparison of the effectiveness of placebo and a-blocker therapy for the treatment
More informationInternational Committee for Monitoring Assisted Reproductive
SEXUAL DYSFUNCTION AND INFERTILITY Comparing the Effectiveness of Dietary Vitamin C and Exercise Interventions on Fertility Parameters in Normal Obese Men Bahare Rafiee, 1,2 Mohammad Hossein Morowvat,
More informationYutaka; SAKAMOTO, Hiromi. Citation 泌尿器科紀要 (1986), 32(10):
Title46XX male; report of case OKUYAMA, Akihiko; KONDO, Nobuyuki; Author(s) NAKAMURA, Masahiro; SONODA, Takao; Yutaka; SAKAMOTO, Hiromi Citation 泌尿器科紀要 (1986), 32(10): 1539-1542 Issue Date 1986-10 URL
More informationChapter1 Introduction
Chapter1 Introduction Male subfertility is a very significant global problem. Epidemiological data show that approximately 1-in-7 couples are classed as subfertile [1]. Sperm dysfunction is the single
More informationTUE Physician Guidelines Medical Information to Support the Decisions of TUE Committees MALE HYPOGONADISM MALE HYPOGONADISM
1. Medical Condition Hypogonadism in men is a clinical syndrome that results from failure of the testes to produce physiological levels of testosterone (testosterone deficiency) and in some instances normal
More information2017 United HealthCare Services, Inc.
UnitedHealthcare Pharmacy Clinical Pharmacy Programs Program Number 2017 P 1143-4 Program Prior Authorization/Notification Medication Menopur (menotropins) * P&T Approval Date 8/2014, 5/2015, 5/2016, 5/2017
More informationAnimal Reproductive Systems. Chapter 42
Animal Reproductive Systems Chapter 42 Impacts, Issues Male or Female? Body or Genes? Body and genes don t always match male or female characteristics also depend on hormones mutations can result in intersex
More informationInformation for Patients. Male infertility. English
Information for Patients Male infertility English Table of contents What is male infertility?... 3 Diagnosis... 3 Medical history... 3 Physical examination... 3 Hormone blood tests... 3 Semen analysis...
More information