Support for Fertility and Infertility Treatment

Transcription

1 Support for Fertility and Infertility Treatment Obesity causes an alteration to the hormones associated with women fertility Many different studies have concluded that obesity is related to impaired fertility. Obese women have changes in their hormonal balance that create disturbances in the menstrual cycle. It also affects the development of the endometrial lining and the implantation. For these women, it is a good idea to start a controlled weight-reduction program to increase their fertility rate. Tobacco use amongst women directly affect regular ovulation Tobacco contains many different substances, among these, Benzo[a]pyrene has been identified as a direct trigger of abnormal follicular development in early ovulation. It affects the enzymes and activates the death genes of the preovulatory follicles, thus delaying its growth and decreasing its viability. Comment: The best infertility treatment would always recommend stopping smoking. Higher levels of stress are associated with increased risk of infertility Biomarkers of stress, such as cortisol and alpha-amylase, were measured on women s saliva samples along with questionnaires and daily journals. After 12 months follow-up, the conception rate was reduced by 29% when stress biomarkers were high. The exposure to environment contaminants has been found to reduce male semen quality The exposure of men to different endocrine disruptors from the environment, such as organochlorines, dioxins, phthalates, phytoestrogens, and chemical mixtures such as pesticides and tobacco, were found to reduce semen quality, increasing the probability of male infertility. Comment: This should all be explained in any male infertility treatment program.

2 Intake of Omega-3 fatty acids stimulates the ovaries and improve embryo morphology High intakes of Omega-3 polyunsaturated fatty acids found in fish alpha-linolenic acid, increase the baseline estradiol level, essential for the ovarian stimulation and embryo morphology. Comment: Should be part of infertility programs. High-fat diets decreases fertilization rates It has been found that high-fat diets in women causes lipotoxicity and increases stress in the endoplasmic reticulum, with high probabilities of cell death in the oocyte. Additionally, it is related with increased anovulation and decreased effectiveness of in vitro fertilization.comment: Addressing this is part of a fertility diet plan. Dietary antioxidant intake increases rates of pregnancy in women with unexplained infertility It has been found a shorter time to pregnancy among women consuming dietary sources of Vitamin C, β-carotene, and Vitamin E. Comment:A Fertility Doctor should be recommending as part of yourfertility treatment. Intake of vegetable protein may reduce infertility for ovulatory causes A comparison was performed between women taking protein from animal and plant origin. The results suggest that replacing animal sources of protein with their vegetable counterparts may increase ovulation rates in women with ovulatory infertility.

3 High carbohydrate intake increases the risk of anovulatory infertility Both high carbohydrate intake and high glycemic index are related to increased risk of anovulatory infertility in healthy women. Therefore, the amount and quality of carbohydrate may determine regular ovulatory cycles. Different cofactors, coenzymes, and antioxidants are essential for mitochondrial function and may enhance fertility rates The mitochondrial diet joins different nutritional sources of cofactors, coenzymes, and antioxidants, such as Vitamin C, E, B6, Selenium, Catechins, Carnitine, and others. These nutrients have been found to promote mitochondrial function and may play a major role in infertility treatments. Comment: The best infertility center would recommend a personal nutrition program. The type of fatty acids consumed affects the composition of the zygote membrane n-3 fatty acids was compared to n-6 fatty acids, and only the former has been found positively correlated with pregnancy. The attachment of the zygote to the uterus depends on the composition of the membrane, and the most positive effect for fertilization was found with linoleic acid. Dairy intake does not harm fertility rates Data from cohort studies in Denmark and North America, with 2426 women were analyzed. There was no clear association between low or high-fat dairy intake and fertility rates. There was only a slight higher fecundability after greater consumption of phosphorus and lactose.

4 Adherence to fertility diet patterns increases fertility rates Following fertility diets with higher consumption of monounsaturated fats, vegetable proteins, low glycemic carbohydrates, high fat dairy, multivitamins, and iron from plants favorably influences fertility in healthy women. Mediterranean-type diet enhances fertility when compared to Western-type diets A Spanish cohort of 485 women with Mediterranean and Western dietary patterns was followed, and there was a lower risk of infertility in the Mediterranean diet group. Comment: All Male infertility and Female infertility should be supported by an infertility center of excellence that recommends personalized diets. Iron intake decreases ovulatory infertility A prospective cohort study was performed among 18,555 women who attempted pregnancy or became pregnant. Higher non-heme iron, such as the one type found in plant foods, was associated with lower ovulatory infertility rates. Comment:Iron must be checked out before any ivf fertility treatment by the fertility clinic. Dietary patterns are associated with higher semen quality in young men The prudent diet pattern, characterized by high intake of fish, chicken, fruit, vegetables, legumes, and whole grains, was associated with higher semen quality (sperm concentration, motility and morphology) in young men. Comment: A clinical nutritionist can support Male fertility with the correct diet. Iodine deficient populations have a higher rate of reproductive failure Low iodine intake, and severe iodine deficiency were related to repeated miscarriages and stillbirth in iodine deficient areas of Senegal. The influence of iodine on reproduction has been clearly demonstrated. Comment: Iodine deficiency is also common in New Zealand, Australia and several European countries. All good fertility tests would include iodine testing.

5 Folate, zinc and antioxidants contribute to male and female fertility rates Folate has a role on spermatogenesis ando oocyte quality. Zinc is implicated in sperm maturation, ovulation and the menstrual cycle. Antioxidants balance the levels of reactive oxygen species and influence DNA stability. Therefore, the concentration of these three factors on nutrition improves fertility rates in males and females. Different micronutrients have been found to have a positive impact on fertility Vitamin B6, C, D, E, folic acid, iodine, selenium, iron, and DHA have a positive impact on fertility treatments. Supplementation should take pathophysiology, clinical studies, and upper limits into account. Comment: Your fertility center / fertility clinic, should be testing for all of the above as part of assessing for fertility problems and collating your fertility diet plan.