GnRHа/PMSG/HCG. GnRHx (PMSG/HCG) : ) [Pregnant Monoposal Serum Gonadotropine = GnRHx (PMSG/HCG)]

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1 (1384 ) GnRHа/PMSG/HCG * GnRHx (PMSG/HCG) :... (N=30) ( ) : ) [Pregnant Monoposal Serum Gonadotropine = GnRHx (PMSG/HCG)]. ( ) (... :.(P<0/05) :. - 84/5/3 : 84/3/2 : : 83/11/10 : : : * bazzy_par@yahoo.com:

2 1384 / 1 /16. (Rat). ).(. (Rat) (Pregnant 10 monoposal Serum Gonadotropine= PMSG) 48 (Human Chorionic Gonadotropine 10. =HCG). ) ( 120. (PH= 7/4).(2 1).(3) %15 (5) (4)..(6).(7 8)..(9 10) (Implantation window).(11 12) (Assisted Reproductive Techniques= ART)...(13-15) :.(16-18)

3 17 /. a/b : -. : :..(1 ). (Nuclear Channel System=NCS).(3 2 ) %2/5 ) (. Philips. 20. : Vv (Volume fraction = Vv) Vv Vv (RER) Vv. : 8. axial ratio d=axb (Vv) (1 0/215±0/ /725±0/019 0/901±0/ 013 0/004±0/015 0/003±0/ 028 0/013±0/068 /011±0/ 089 Vv 0/320±0/ RER 0 Mean ±SE *.(P<0/05)

4 1384 / 1 /18 -(1 (- ) ( ).(x3200) ( ). -(2 (- ) ( ).(x3200)( ) NCS. ( )

5 19 /. -(3 (x.15000) ( ) ( NCS). ) ( ).(3) ( (Implantation window).(19). %75.(12). : 1.(P<0/05) (12/43 ±0/122) Axial Ratio (9/32 ± 0/115) (2/90 ± 0/168).(P<0/05)..

6 1384 / 1 /20.. (Nikolettos) (17). IVF 124 (Garcia)..(16) (Tavanitou).(13).(21).( )...(14 13) ( ).(N=30)..

7 21 /. References: 1. Hedegaard M. Life style, work and stress, and pregnancy outcome. Curr Opin Obstet Gynecol 1999;11: Shilkina IA. Effect of overheating on Spermatogenesis in Mice and The value of heat training in adapting sex cells to The effect of high Temperatures. Biull Eksp Sio Med 1976; 82: Lions FH. Infertility: ethiology, evaluation and treatment. Drugs Today (Barce) 2000; 36: Yates CA, De Kretser DM. Male-factor infertility and in vitro fertilization. J In Vitro Fert Embryo Transf. 1987; 4: Machelle M, Sebel MD. Infertility, a comperhensive text. Second ed. Appleton and Stamford press, 1999, Rice A, Chard T. Cytokines in implantation. Cytokine Growth Factor Rev 1998; 9: Wilcox AJ, Wenberg CR. Time of implantation of the conceptus and loss of pregnancy. New Eng J Med 1999; 340: Enders Ac, Schlafke S. Cytological aspects of trophoblast-uterine interaction in early implantation. Am J Anat 1969;125: Ziegler D. Endometrial receptivity for implantation, hormonal control of endometrial receptivity. Hum Reprod 1995; 10: Bergeron C, Cornel C. Effects of teals stradiol on the secretory transformation of human endometrium and plasma gonadotropin. J Clin Endocrinol Metabol 1992; 74: Speroff L, Glass R, Kase N. Clinical Gynecologic Endocrinology and Infertility, 5th ed, Maryland: Williams & Wilkins, 1994, Beato M and Klug J. Steroid hormone receptors, an update. Human Reprod Update 2000; 3: Tavaniotou A, Smitz J, Bourgain C, Devroey P. Ovulation induction disrupts luteal phase function. Ann N Y Acad Sci 2001; 943: Marci R, Senn A, Dessole S, Chanson A, Loumaye E, De Grandi P, Germond M. A low-dose stimulation protocol using highly purified folliclestimulating hormone can lead to high pregnancy rates in in vitro fertilization patients with polycystic ovaies who are at risk of a high ovarian response to gonadotropins. Fertil Steril 2001; 75: Nikas G. Endometrial receptivity: changes in cell-surface morphology. Semin Reprod Med 2000; 8: Garcia J, Nikas G, Pellicer A, Simon C. Assessment of uterine receptivity and timing of embryo transfer using the detection of pinopodes. Human Reprod 1997; 12: Nikolettos N, Asimakopoulos M, Vakalopoulos I, et al. Endometrial fluid accumulation during controlled ovarian stimulation for ICSI treatment. A report of three cases. Clin Exp Obstet Gynecol 2002; 29: Dockery P, Khalid J, Sarani SA, et al. Changes in basement membrane thickness in the human endometrium during the luteal phase of the menstrual cycle. Hum Reprod Update 1998; 4 : Bergh PA, Navot D. The impact of embryonic development and endometrial maturity on the timing of implantation. Fertil Streil 1992; 58: Sarantis D, Roche A. Displacement of receptivity for nidation in the rat: a scanning electron microscopy study. Hum Reprod 1988; 3: Rongieres-Bertrand C, Olivennes F, Righini C, et al. Revival of the natural cycles in in-vitro fertilization with the use of a new gonadotrophinreleasing hormone antagonist (Cetrorelix): a pilot study with minimal stimulation. Hum Reprod 1999; 14:683-8.

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