History of the Powerlink System Design and Clinical Results. Edward B. Diethrich Arizona Heart Hospital Phoenix, AZ

Size: px
Start display at page:

Download "History of the Powerlink System Design and Clinical Results. Edward B. Diethrich Arizona Heart Hospital Phoenix, AZ"

Transcription

1 History of the Powerlink System Design and Clinical Results Edward B. Diethrich Arizona Heart Hospital Phoenix, AZ

2 Powerlink System: Unibody-Bifurcated Design Long Main Body Low-Porosity Proprietary eptfe Formulation Cobalt Chromium Alloy Stent Single-wire Main Body Construction Fully Supported

3 Powerlink System History AHI Arizona Heart Hospital

4 Powerlink System History 1999 Japanese Shonin Trial Begins 2000 U.S. Pivotal Trial Begins 2000 Powerlink Obtains CE Mark 2004 FDA Marketing Approval

5 Anatomical Fixation Mimics the shape of the natural aorta Sits at the bifurcation Provides support to resist downward force due to pulsatile bloodflow Raithel, et al. Endovascular Today, June 2006.

6 Powerlink U.S. Pivotal Trial (192 pts.) Powerlink Control P-value Age < Successful Deployment 188/ % N/A Patients with at least 1 Major AE (0-30days) N/A 13/ % 14/ % < All Death < 30 days 2*/ % 4/66-6.1% < Anesthesia Time (min) < Procedure Time (min) < Blood Loss (l) < Days in ICU < Days to Discharge < Defined as death, MI, stroke, AAA rupture, conversion, secondary procedure, coronary intervention, renal failure, or respiratory failure * Not device related Carpenter JP, et al. Midterm results of the multicenter trial of the Powerlink bifurcated system for endovascular aortic aneurysm repair. J Vasc Surg 2004;40:

7 Endologix U.S. Multicenter Trial 8 migrations through 72 mos. 1 secondary procedure (add l cuff) No clinical sequelae in 7 patients No aneurysm ruptures No wire fractures No graft material failures

8 Freedom from AAA Mortality % Survival P= Powerlink Control Months Post-Implant Endologix U.S. Multicenter Trial

9 Endologix U.S. Multicenter Trial Freedom from Device Related Re-Hospitalization % Freedom from Device-Related Re-hospitalization Months Post- Implant

10 Endologix U.S. Multicenter Trial Core Lab Analysis Endoleaks (All Types, New and Persistent) 1 mo (N=123) 6 mo (N=119) 12 mo (N=147) 24 mo (N=142) 36 mo (N=130) 48 mo (N=119) 60 mo (N=72) 72 mo (N=16) All Endoleaks Type I Type II Type III Type IV Multiple Indeterminate As of April 30, 2007

11 Secondary Procedures Through 72 Months* 34 procedures in 26 patients Endoleak 23 (Cuffs, embolization, balloon dilatation, stent) Type II Endoleak 17 Type I Endoleak 6 Graft Limb Occlusion 7 Embolectomy, Stent, PTA, or Lytic Therapy Native Artery Procedures 3 Migration - 1 * As of April 2007 Endologix U.S. Multicenter Trial

12 Endologix U.S. Multicenter Trial AAA Sac After EVAR Decrease in volume in 83% of pts. by 60 months 6 patients with volume expansion 4 Type II endoleaks were reported in patients with volume expansion (none of which resulted in secondary procedures).

13 AAA Sac Regression - Diameter Diameter (mm) Month 6 Month 12 Month 24 Month 36 Month 48 Month 60 Month 72 Month Follow-up Months Endologix U.S. Multicenter Trial

14 Endologix U.S. Multicenter Trial AAA Sac Regression - Volume Volume (cc) Month 6 Month 12 Month 24 Month 36 Month 48 Month 60 Month 72 Month Follow-up Months

15 Courtesy of Rod White, MD Sac Dynamics After Powerlink 1- Mo. 2-Yr. 3-Yr. 4-Yr. 5-Yr. Mean Max. Sac Angle Mean Max. Sac Diameter Mean Aortic Volume Mean Distance Between Distal Renal & Bifurcation mm 43.0 mm 41.8 mm 39.5 mm 35.2 mm ml ml 117.2ml ml ml mm mm mm mm mm

16 Courtesy of Rod White, MD Sac Dynamics After Powerlink 82.8 % (n = 53/64) of patients exhibited an increase in sac angle (aorta becoming straighter) % (n = 25/64) of patients exhibited straightening by 10 or more 17.2 % (n = 11/64) of patients exhibited no change or had a slight decrease in sac angle (aorta becoming more angulated) -3.1 % (n = 2/64) of patients exhibited angulation decreasing by 10 or more

17 Courtesy of Rod White, MD

18 Courtesy of Rod White, MD

19 Challenging Infrarenal Aortic Neck Anatomy Large diameter (>28mm) Short landing zone (<15mm) Extreme Angulation Accessory renal arteries Reverse tapered neck

20 Objective Evaluate the incidence of Type I endoleaks and device migration in patients with reverse tapered neck anatomy Determine effect on seal zone Incidence of secondary interventions in patients with this neck geometry

21 Reverse Tapered Neck Sub-Group Analysis (50 of 192) Proximal Diameter mm ( ) Distal Diameter mm ( )

22 Follow-up of Sub-Group Mean follow-up: 40.2 months Range: 1 mo 64 mo No AAA-related deaths No secondary procedures for proximal Type I endoleak Graft migration: 1 (12.5mm); no clinical sequelae

23 Summary of Late Clinical Findings 97.9 % Freedom from AAA-Related 6 yrs % Freedom from 6 yrs. No aneurysm ruptures Only 1 late conversion (@ 1 yr.) No eptfe graft material failures at 6 years No cobalt chromium stent graft failure or fatigue at 6 years

24 Endologix New Product Developments

25 Visiflex SurePass Delivery System Contralateral Wire Access 0.14 Wire

26 Visiflex- Passage of 0.14 Wire Through Contralateral Limb Catheter

27 Visiflex IS Next Generation Delivery System Integrated 19 Fr Introducer Extensions deployed thru Integrated Sheath Hemostatic Clamp for Exchanges Simplified deployment Improved ergonomics

28 Ectatic Iliacs Aneurysmal Iliac Arteries >14mm in 20% of Patients

29 Large Diameter Limb Extensions Treats up to 23mm Iliacs

30 Challenging Necks Strong support from anatomical fixation Use existing Powerlink bifurcated stent grafts Develop dedicated cuffs for: Large necks Angulated necks Short necks

31 Cuff Concepts Flexibility Treats up to 32mm Neck Trans-Renal Alignment

32 Innovations- Type III Dissection with Vascular Compromise False Lumen True Lumen True Lumen Abdominal Pain Lower Leg Ischemia

33 Proximal ELG Deployed Persistent Distal True Lumen Compromise

34 Gianturco Stent with Barbs Without Barbs

35 Vascular Compromise Resolved

36 ELG Deployment of Bare Stents to Expand True Lumen Bare Stents

37 Petticoat Concept

38 Investigative Stent to Correct Vascular Compromise Endologix

39 Powerlink System - Conclusions Excellent results in challenging neck anatomy Simple implantation technique Minimally invasive access Anatomical fixation for resistance to migration Low occurrence of secondary procedures Low occurrence of Type II endoleaks Sac regression and improving morphology Proven durability Innovative product pipeline for expanding EVAR indications

40 History of the Powerlink System Design and Clinical Results Edward B. Diethrich Arizona Heart Hospital Phoenix, AZ

A New EVAR Device for Infrarenal AAAs

A New EVAR Device for Infrarenal AAAs A New EVAR Device for Infrarenal AAAs Peter Nelson, MD, MS Assistant Professor of Surgery MM0203 Rev. 01 Current U.S. EVAR Devices Anatomical Fixation Proximal Fixation Powerlink - Endologix Excluder WL

More information

LOWERING THE PROFILE RAISING THE BAR

LOWERING THE PROFILE RAISING THE BAR LOWERING THE PROFILE RAISING THE BAR INNOVATIVE LOW PROFILE. ADVANCED CLINICAL PERFORMANCE. The AFX TM Endovascular AAA System integrates anatomical fixation with an advanced delivery system and graft

More information

The Ventana Off-the-Shelf Graft for Pararenal AAA. Andrew Holden Associate Professor of Radiology Auckland Hospital

The Ventana Off-the-Shelf Graft for Pararenal AAA. Andrew Holden Associate Professor of Radiology Auckland Hospital The Ventana Off-the-Shelf Graft for Pararenal AAA Andrew Holden Associate Professor of Radiology Auckland Hospital Disclosures Andrew Holden, MBChB, FRANZCR Investigator in Nellix and Ventana Trials Clinical

More information

Talent Abdominal Stent Graft

Talent Abdominal Stent Graft Talent Abdominal with THE Xcelerant Hydro Delivery System Expanding the Indications for EVAR Treat More Patients Short Necks The Talent Abdominal is the only FDA-approved device for proximal aortic neck

More information

Nellix Endovascular System: Clinical Outcomes and Device Overview

Nellix Endovascular System: Clinical Outcomes and Device Overview Nellix Endovascular System: Clinical Outcomes and Device Overview Jeffrey P. Carpenter, MD Professor and Chief, Department of Surgery CAUTION: Investigational device. This product is under clinical investigation

More information

Challenging anatomies demand versatility.

Challenging anatomies demand versatility. Challenging anatomies demand versatility. The Distinct Advantages of Separating Seal and Fixation ANATOMICAL FIXATION Unlike proximal fixation designs, the AFX bifurcated unibody endograft allows for natural

More information

ENCORE, a Study to Investigate the Durability of Polymer EVAR with Ovation A Contemporary Review of 1296 Patients

ENCORE, a Study to Investigate the Durability of Polymer EVAR with Ovation A Contemporary Review of 1296 Patients ENCORE, a Study to Investigate the Durability of Polymer EVAR with Ovation A Contemporary Review of 1296 Patients The Ovation System is approved to treat infrarenal abdominal aortic aneurysms and is not

More information

Hostile Proximal Neck: A New Conformable EVAR Device

Hostile Proximal Neck: A New Conformable EVAR Device Hostile Proximal Neck: A New Conformable EVAR Device Young-Guk Ko, M.D., Seoul, Korea Currently Available Devices for EVAR in Korea, 2018 Zenith Flex, Cook Endurant IIs, Medtronic INCRAFT, Cordis AFX2,

More information

Durability of The Endurant Stent-Graft through 5 Years

Durability of The Endurant Stent-Graft through 5 Years Durability of The Endurant Stent-Graft through 5 Years Michel S. Makaroun MD Co-Director, UPMC Heart and Vascular Institute Professor and Chair, Division of Vascular Surgery University of Pittsburgh School

More information

Ovation. Sean Lyden, MD Department Chair, Vascular Surgery Cleveland Clinic

Ovation. Sean Lyden, MD Department Chair, Vascular Surgery Cleveland Clinic Ovation Sean Lyden, MD Department Chair, Vascular Surgery Cleveland Clinic Disclosure Statement of Financial Interest Within the past 12 months, I or my spouse/partner have had a financial interest/arrangement

More information

2015 Clinical Update Endovascular Systems for AAA Repair

2015 Clinical Update Endovascular Systems for AAA Repair Endovascular Systems for AAA Repair 2 Musick Irvine, CA 92618 Tel 949.595.7200 Fax 949.612.1893 www.endologix.com TABLE OF CONTENTS Section Page ABSTRACT... 3 READER S GUIDE... 4 SECTION 1: US PIVOTAL

More information

Robert F. Cuff, MD FACS SHMG Vascular Surgery

Robert F. Cuff, MD FACS SHMG Vascular Surgery Robert F. Cuff, MD FACS SHMG Vascular Surgery Objectives To become familiar with the commercially available fenestrated EVAR graft Discuss techniques to increase success Review available data to determine

More information

Access More Patients. Customize Each Seal.

Access More Patients. Customize Each Seal. Access More. Customize Each Seal. The Least Invasive Path Towards Proven Patency ULTRA LOW PROFILE TO EASE ADVANCEMENT The flexible, ultra-low 12F ID Ovation ix delivery system enables you to navigate

More information

Endovascular Repair o Abdominal. Aortic Aneurysms. Cesar E. Mendoza, M.D. Jackson Memorial Hospital Miami, Florida

Endovascular Repair o Abdominal. Aortic Aneurysms. Cesar E. Mendoza, M.D. Jackson Memorial Hospital Miami, Florida Endovascular Repair o Abdominal Aortic Aneurysms Cesar E. Mendoza, M.D. Jackson Memorial Hospital Miami, Florida Disclosure Nothing to disclose. 2 Mr. X AAA Mr. X. Is a 70 year old male who presented to

More information

Optimizing Accuracy of Aortic Stent Grafts in Short Necks

Optimizing Accuracy of Aortic Stent Grafts in Short Necks Optimizing Accuracy of Aortic Stent Grafts in Short Necks Venkatesh Ramaiah, MD, FACS Medical Director Arizona Heart Hospital Director Peripheral Vascular and Endovascular Research Arizona Heart Institute

More information

Abdominal and thoracic aneurysm repair

Abdominal and thoracic aneurysm repair Abdominal and thoracic aneurysm repair William A. Gray MD Director, Endovascular Intervention Cardiovascular Research Foundation Columbia University Medical Center Abdominal Aortic Aneurysm Endografts

More information

INCRAFT system: Update from the Pivotal INSPIRATION Study

INCRAFT system: Update from the Pivotal INSPIRATION Study INCRAFT system: Update from the Pivotal INSPIRATION Study Michel S. Makaroun MD Co-Director, UPMC Heart and Vascular Institute Professor and Chair, Division of Vascular Surgery University of Pittsburgh

More information

Zenith Renu AAA Converter Graft. Device Description Planning and Sizing Deployment Sequence Patient Follow-Up

Zenith Renu AAA Converter Graft. Device Description Planning and Sizing Deployment Sequence Patient Follow-Up Zenith Renu AAA Converter Graft Device Description Planning and Sizing Deployment Sequence Patient Follow-Up Device description: Device indications The Zenith Renu AAA Converter Graft with Z-Trak Introduction

More information

EVAR replaced standard repair in most cases. Why?

EVAR replaced standard repair in most cases. Why? EVAR replaced standard repair in most cases. Why? Initial major steps in endograft evolution Papazoglou O. Konstantinos M.D. The story of a major breakthrough in vascular surgery 1991 Parodi introduces

More information

Bifurcated system Proximal suprarenal stent Modular (aortic main body and two iliac legs) Full thickness woven polyester graft material Fully

Bifurcated system Proximal suprarenal stent Modular (aortic main body and two iliac legs) Full thickness woven polyester graft material Fully Physician Training Bifurcated system Proximal suprarenal stent Modular (aortic main body and two iliac legs) Full thickness woven polyester graft material Fully supported by self-expanding z-stents H&L-B

More information

Current Status of Abdominal Aortic Stent Grafts. John R. Laird Professor of Medicine Director of the Vascular Center UC Davis Medical Center

Current Status of Abdominal Aortic Stent Grafts. John R. Laird Professor of Medicine Director of the Vascular Center UC Davis Medical Center Current Status of Abdominal Aortic Stent Grafts John R. Laird Professor of Medicine Director of the Vascular Center UC Davis Medical Center Autumn Greetings Disclosure Statement of Financial Interest Within

More information

The Auckland Experience with the Nellix EVAS System. Andrew Holden, MBChB, FRANZCR

The Auckland Experience with the Nellix EVAS System. Andrew Holden, MBChB, FRANZCR The Auckland Experience with the Nellix EVAS System Andrew Holden, MBChB, FRANZCR Disclosure Speaker name: Associate Professor Andrew Holden I have the following potential conflicts of interest to report:

More information

TriVascular Ovation Prime Abdominal Stent Graft System

TriVascular Ovation Prime Abdominal Stent Graft System TriVascular Ovation Prime Abdominal Stent Graft System Science of the Seal O-Ring Sealing Technology O-Ring Sealing in Proven Engineering Solutions O-rings are designed to seal by blocking the flow of

More information

My personal experience with INCRAFT in standard and challenging cases

My personal experience with INCRAFT in standard and challenging cases My personal experience with INCRAFT in standard and challenging cases G Pratesi, MD Vascular Surgery University of Rome Tor Vergata giovanni.pratesi@uniroma2.it Disclosure Speaker name: Giovanni Pratesi,

More information

Degeneration of the Neck Post Implementation - a New Era of AAA Stent

Degeneration of the Neck Post Implementation - a New Era of AAA Stent Degeneration of the Neck Post Implementation - a New Era of AAA Stent New Mexico Heart Institute Albuquerque, New Mexico USA - Gore Current FDA-Approved EVAR Devices Sealing Mechanism Endologix Lombard

More information

Durable outcomes. Proven performance.

Durable outcomes. Proven performance. Durable outcomes. Proven performance. GORE EXCLUDER AAA Endoprosthesis GORE EXCLUDER Iliac Branch Endoprosthesis GORE EXCLUDER AAA Endoprosthesis The most-studied* EVAR stent graft designed for durable

More information

Current Status of EVAR for Infrarenal AAA. 31 st Annual Florida Vascular Society. PENN Surgery

Current Status of EVAR for Infrarenal AAA. 31 st Annual Florida Vascular Society. PENN Surgery Current Status of EVAR for Infrarenal AAA 31 st Annual Florida Vascular Society PENN Surgery No Disclosures Stent Grafts Design Related Differences What really matters? Modular Unibody Supported Unsupported

More information

Anatomical challenges in EVAR

Anatomical challenges in EVAR Anatomical challenges in EVAR M.H. EL DESSOKI, MD,FRCS PROFESSOR OF VASCULAR SURGERY CAIRO UNIVERSITY Disclosure Speaker name:... I have the following potential conflicts of interest to report: Consulting

More information

Aortic stents, types, selection, tricks in deployment.

Aortic stents, types, selection, tricks in deployment. Aortic stents, types, selection, tricks in deployment. Hamdy Soliman.M.D,FSCAI Consultant of Cardiology&Head of Endovascular Unit National Heart Institute Endovascular Treatment of Thoracic Aortic Aneurysms

More information

Bilateral use of the Gore IBE device for bilateral CIA aneurysms and a first interim analysis of the prospective Iceberg registry

Bilateral use of the Gore IBE device for bilateral CIA aneurysms and a first interim analysis of the prospective Iceberg registry Bilateral use of the Gore IBE device for bilateral CIA aneurysms and a first interim analysis of the prospective Iceberg registry Michel MPJ Reijnen, MD, PhD Department of Vascular Surgery, Rijnstate Hospital

More information

CAUTION: The Nellix EndoVascular Aneurysm Sealing System is an investigational device. Limited by federal (or United States) law to investigational

CAUTION: The Nellix EndoVascular Aneurysm Sealing System is an investigational device. Limited by federal (or United States) law to investigational Safety and Effectiveness Results of the Nellix System IDE Pivotal Trial for Endovascular Aneurysm Sealing PRESENTED BY: Jeffrey P. Carpenter, MD National Principal Investigator Professor and Chairman,

More information

EndoVascular Aneurysm Sealing (EVAS) with Nellix

EndoVascular Aneurysm Sealing (EVAS) with Nellix 1 2 EndoVascular Aneurysm Sealing (EVAS) with Nellix Designed to seal entire aneurysm with contained biostable polymer Non-modular design with complete fixation Expands endovascular patient eligibility

More information

Young-Guk Ko, M.D. Severance Cardiovascular Hospital, Yonsei University Health System,

Young-Guk Ko, M.D. Severance Cardiovascular Hospital, Yonsei University Health System, Young-Guk Ko, M.D., Dangas G, J Am Coll Cardiol Intv 2012;5:1071 All-cause Mortality Dangas Severance G, J Am Coll Cardiovascular Cardiol Intv Hospital, 2012;5:1071 Yonsei University Health System Aneurysm-related

More information

Right Choice for Right Angles

Right Choice for Right Angles Right Choice for Right Angles The Anatomy of Technology Aorfix gives you technology that conforms to patient anatomy, optimising both procedure and post-operative performance. Fishmouth for optimum neck

More information

14F OD Ovation Abdominal Stent Graft System

14F OD Ovation Abdominal Stent Graft System 14F OD Ovation Abdominal Stent Graft System 2 Year Results from the European Study Dierk Scheinert, MD Center for Vascular Medicine Angiology and Vascular Surgery Park Hospital Leipzig, Germany Disclosure

More information

Technique and Tips for Complicated AAA Cases with Stent Graft

Technique and Tips for Complicated AAA Cases with Stent Graft Technique and Tips for Complicated AAA Cases with Stent Graft Seung-Woon Rha, MD, PhD FACC, FAHA, FESC, FSCAI, FAPSIC Cardiovascular Center, Korea University Guro Hospital Mar 15, 2018 LINC AP 2018 Endoleak;

More information

The evolution. AORFIX AAA Stent Graft now with the new AORFLEX Delivery System

The evolution. AORFIX AAA Stent Graft now with the new AORFLEX Delivery System The evolution of AORFIX AORFIX AAA Stent Graft now with the new AORFLEX Delivery System The confident choice for the right angles AORFIX the only AAA stent graft approved for all angulations from 0 90,

More information

Challenges with Complex Anatomies Advancing Care in Endovascular Aortic Treatment

Challenges with Complex Anatomies Advancing Care in Endovascular Aortic Treatment Challenges with Complex Anatomies Advancing Care in Endovascular Aortic Treatment Robert Y. Rhee, MD Chief, Vascular and Endovascular Surgery Director, Aortic Center Maimonides Medical Center Brooklyn,

More information

How to Categorize the Infrarenal Neck Properly? I Van Herzeele Dept. Thoracic and Vascular Surgery, Ghent University, Belgium

How to Categorize the Infrarenal Neck Properly? I Van Herzeele Dept. Thoracic and Vascular Surgery, Ghent University, Belgium How to Categorize the Infrarenal Neck Properly? I Van Herzeele Dept. Thoracic and Vascular Surgery, Ghent University, Belgium Disclosure Speaker name: Isabelle Van Herzeele I have the following potential

More information

Anatomy-Driven Endograft Selection for Abdominal Aortic Aneurysm Repair S. Jay Mathews, MD, MS, FACC

Anatomy-Driven Endograft Selection for Abdominal Aortic Aneurysm Repair S. Jay Mathews, MD, MS, FACC Anatomy-Driven Endograft Selection for Abdominal Aortic Aneurysm Repair S. Jay Mathews, MD, MS, FACC Interventional Cardiologist/Endovascular Specialist Bradenton Cardiology Center Bradenton, FL, USA Disclosures

More information

From 1996 to 1999, a total of 1,193 patients with

From 1996 to 1999, a total of 1,193 patients with THE ANEURX CLINICAL TRIAL AT 8 YEARS Lessons learned following the US AneuRx clinical trial from 1996 to 2004. BY CHRISTOPHER K. ZARINS, MD From 1996 to 1999, a total of 1,193 patients with infrarenal

More information

Abdominal Aortic Aneurysm (AAA)

Abdominal Aortic Aneurysm (AAA) Abdominal Aortic Aneurysm (AAA) Vascular Workshop: Objectives Anatomy Keith VanHaltren Indications Technique Cases Abdominal Aorta: Normal Size Abdominal aortic aneurysm: Definition Normal diameter of

More information

Treatment options of late failures of EVAS. Michel Reijnen Rijnstate Arnhem The Netherlands

Treatment options of late failures of EVAS. Michel Reijnen Rijnstate Arnhem The Netherlands Treatment options of late failures of EVAS Michel Reijnen Rijnstate Arnhem The Netherlands Disclosure Speaker name: Michel Reijnen I have the following potential conflicts of interest to report: Consulting

More information

No Neck Is Needed! Treat the Aneurysm Instead! Andrew Holden, MD Associate Professor of Radiology Auckland City Hospital

No Neck Is Needed! Treat the Aneurysm Instead! Andrew Holden, MD Associate Professor of Radiology Auckland City Hospital No Neck Is Needed! Treat the Aneurysm Instead! Andrew Holden, MD Associate Professor of Radiology Auckland City Hospital Disclosures Andrew Holden, MBChB, FRANZCR No financial investment to disclose Investigator

More information

RadRx Your Prescription for Accurate Coding & Reimbursement Copyright All Rights Reserved.

RadRx Your Prescription for Accurate Coding & Reimbursement Copyright All Rights Reserved. Interventional Radiology Coding Case Studies Prepared by Stacie L. Buck, RHIA, CCS-P, RCC, CIRCC, AAPC Fellow President & Senior Consultant INDICATION: Abdominal aortic aneurysm. INTERVENTIONAL RADIOLOGIST:

More information

What's on the Horizon for AAA: Unilateral & Percutaneous, "UP-EVAR" System Zoran Rancic M.D., Ph.D.

What's on the Horizon for AAA: Unilateral & Percutaneous, UP-EVAR System Zoran Rancic M.D., Ph.D. What's on the Horizon for AAA: Unilateral & Percutaneous, "UP-EVAR" System Zoran Rancic M.D., Ph.D. Clinic for Cardiovascular Surgery University Hospital Zurich DISCLOSURES COMMON SITUATIONS FOR UNILATERAL

More information

Taming The Aorta. David Minion, MD Program Director, Vascular Surgery University of Kentucky Medical Center Lexington, Kentucky, USA

Taming The Aorta. David Minion, MD Program Director, Vascular Surgery University of Kentucky Medical Center Lexington, Kentucky, USA Taming The Aorta David Minion, MD Program Director, Vascular Surgery University of Kentucky Medical Center Lexington, Kentucky, USA Faculty Disclosure Consulting: Endologix, Cook 1 Objectives Review the

More information

Abdominal Aortic Aneurysm 가천대길병원 이상준

Abdominal Aortic Aneurysm 가천대길병원 이상준 Abdominal Aortic Aneurysm 가천대길병원 이상준 1 Definition Diameter of the aorta 1.5 times greater than normal. Most are infrarenal, and a significant number extend down into one or both iliac arteries Abdominal

More information

Ancillary Components with Z-Trak Introduction System

Ancillary Components with Z-Trak Introduction System Ancillary Components with Z-Trak Introduction System Zenith Flex AAA Endovascular Graft Ancillary Components Converter Converters can be used to convert a bifurcated graft into an aortouniiliac graft if

More information

Analysis of Type IIIb Endoleaks Encountered with Endologix Endografts

Analysis of Type IIIb Endoleaks Encountered with Endologix Endografts Analysis of Type IIIb Endoleaks Encountered with Endologix Endografts Alan R. Wladis, MD, FACS, David Varnagy, MD, FACS, Manuel R. Perez-Izquierdo, MD, Mark Ranson, MD FACS, Delos Clift, MD FACS, Rebecca

More information

Abdominal Aortic Aneurysms. A Surgeons Perspective Dr. Derek D. Muehrcke

Abdominal Aortic Aneurysms. A Surgeons Perspective Dr. Derek D. Muehrcke Abdominal Aortic Aneurysms A Surgeons Perspective Dr. Derek D. Muehrcke Aneurysm Definition The abnormal enlargement or bulging of an artery caused by an injury or weakness in the blood vessel wall A localized

More information

Experience of endovascular procedures on abdominal and thoracic aorta in CA region

Experience of endovascular procedures on abdominal and thoracic aorta in CA region Experience of endovascular procedures on abdominal and thoracic aorta in CA region May 14-15, 2015, Dubai Dr. Viktor Zemlyanskiy National Research Center of Emergency Care Astana, Kazakhstan Region Characteristics

More information

Improving Endograft Durability with EndoAnchors

Improving Endograft Durability with EndoAnchors Improving Endograft Durability with EndoAnchors William D. Jordan, Jr., M.D. John E. Skandalakis Chair in Surgery Professor and Chief Division of Vascular Surgery and Endovascular Therapy Emory University

More information

GORE EXCLUDER AAA Endoprosthesis ANNUAL CLINICAL UPDATE OCTOBER Section I Clinical experience. Section II Worldwide commercial experience

GORE EXCLUDER AAA Endoprosthesis ANNUAL CLINICAL UPDATE OCTOBER Section I Clinical experience. Section II Worldwide commercial experience GORE EXCLUDER AAA Endoprosthesis ANNUAL CLINICAL UPDATE OCTOBER 2018 Abstract This annual clinical update provides a review of the ongoing experience with the GORE EXCLUDER AAA Endoprosthesis used in the

More information

Mid-term results of 300+ patients treated by endovascular aortic sealing (EVAS)

Mid-term results of 300+ patients treated by endovascular aortic sealing (EVAS) Mid-term results of 300+ patients treated by endovascular aortic sealing (EVAS) Jean-Paul P.M. de Vries Dept Vascular Surgery St. Antonius Hospital, Nieuwegein,The Netherlands On behalf of the DEVASS study

More information

NASDAQ: ELGX December Innovation that Empowers

NASDAQ: ELGX  December Innovation that Empowers NASDAQ: ELGX www.endologix.com December 2014 Innovation that Empowers Safe Harbor This presentation contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act

More information

How to select FEVAR versus EVAR + endoanchors in short-necked AAAs

How to select FEVAR versus EVAR + endoanchors in short-necked AAAs How to select FEVAR versus EVAR + endoanchors in short-necked AAAs Jean-Paul P.M. de Vries, Richte C.L. Schuurmann St. Antonius Hospital Nieuwegein, The Netherlands 21st Critical Issues Congress Nuernberg,

More information

Considerations for a Durable Repair

Considerations for a Durable Repair Considerations for a Durable Repair Eric Verhoeven, MD, PhD, A. Katsargyris, MD Department of Vascular and Endovascular Surgery, Paracelsus Medical University, Nuremberg, Germany Disclosures William Cook

More information

EVAR Revision Setting - How can Heli-FX EndoAnchors improve the outcomes?

EVAR Revision Setting - How can Heli-FX EndoAnchors improve the outcomes? D. Böckler Department of Vascular and Endovascular Surgery University Hospital Heidelberg EVAR Revision Setting - How can Heli-FX EndoAnchors improve the outcomes? Disclosures Speaker name: Dittmar Böckler

More information

MODERN METHODS FOR TREATING ABDOMINAL ANEURYSMS AND THORACIC AORTIC DISEASE

MODERN METHODS FOR TREATING ABDOMINAL ANEURYSMS AND THORACIC AORTIC DISEASE MODERN METHODS FOR TREATING ABDOMINAL ANEURYSMS AND THORACIC AORTIC DISEASE AAA FACTS 200,000 New Cases Each Year Ruptured AAA = 15,000 Deaths per Year in U.S. 13th Leading Cause of Death 80% Chance of

More information

EVAS using Nellix in my practice Where are we today?

EVAS using Nellix in my practice Where are we today? EVAS using Nellix in my practice Where are we today? Prof. dr. Michel MPJ Reijnen Department of Vascular Surgery, Rijnstate Hospital Arnhem Faculty of Science and Technology, University of Twente The Netherlands

More information

Quick Reference Guide

Quick Reference Guide Quick Reference Guide Indications for Use The AFX Endovascular AAA System is indicated for endovascular treatment in patients with AAA. The devices are indicated for patients with suitable aneurysm morphology

More information

FROM THE EVERYDAY TO THE EXTRAORDINARY

FROM THE EVERYDAY TO THE EXTRAORDINARY FROM THE EVERYDAY TO THE EXTRAORDINARY Created with the collaboration of more than 250 physicians around the world, ENDURANT empowers you to create stronger outcomes for more patients, including those

More information

Influence of patient selection and IFU compliance on outcomes following EVAS

Influence of patient selection and IFU compliance on outcomes following EVAS Influence of patient selection and IFU compliance on outcomes following EVAS LUNCH SYMPOSIUM LINC 2017 Jan MM Heyligers, MD, PhD, FEBVS Consultant Vascular Surgeon Elisabeth TweeSteden Hospital Tilburg,

More information

The clinical update for the Zenith AAA Endovascular Graft has included results from the Zenith AAA Endovascular Graft multi-center clinical study,

The clinical update for the Zenith AAA Endovascular Graft has included results from the Zenith AAA Endovascular Graft multi-center clinical study, The clinical update for the Zenith AAA Endovascular Graft has included results from the Zenith AAA Endovascular Graft multi-center clinical study, the 36 mm diameter Zenith Flex AAA Endovascular Graft

More information

Acute dissections of the descending thoracic aorta (Debakey

Acute dissections of the descending thoracic aorta (Debakey Endovascular Treatment of Acute Descending Thoracic Aortic Dissections Nimesh D. Desai, MD, PhD, and Joseph E. Bavaria, MD Acute dissections of the descending thoracic aorta (Debakey type III or Stanford

More information

THE ENDURANT STENT GRAFT IN HOSTILE ANEURYSM NECK ANATOMY

THE ENDURANT STENT GRAFT IN HOSTILE ANEURYSM NECK ANATOMY THE ENDURANT STENT GRAFT IN HOSTILE ANEURYSM NECK ANATOMY Patrice Mwipatayi FCS (SA), MMed, FRACS Professor of Vascular surgery Royal Perth Hospital, University of Western Australia, Perth, WA Co-Authors:

More information

EVAS is Associated with Lower All-Cause Mortality

EVAS is Associated with Lower All-Cause Mortality EVAS is Associated with Lower All-Cause Mortality Marc L Schermerhorn, MD Chief, Division of Vascular and Endovascular Surgery Beth Israel Deaconess Medical Center Professor of Surgery Harvard Medical

More information

Aortic Neck Issues Associated Clinical Sequelae/Implications for Graft Choice

Aortic Neck Issues Associated Clinical Sequelae/Implications for Graft Choice Aortic Neck Issues Associated Clinical Sequelae/Implications for Graft Choice Eric Verhoeven, MD, PhD, A. Katsargyris, MD Department of Vascular and Endovascular Surgery, Paracelsus Medical University,

More information

12-year Experience with the Endologix Powerlink R Device in Endovascular Repair of Abdominal Aortic Aneurysms

12-year Experience with the Endologix Powerlink R Device in Endovascular Repair of Abdominal Aortic Aneurysms 11 12-year Experience with the Endologix Powerlink R Device in Endovascular Repair of Abdominal Aortic Aneurysms Ziheng Wu 1, Lefeng Qu 2, Dieter Raithel 3 and Konstantinos Xiromeritis³ 1 Department of

More information

Vascular V12. Covered Stent. The New Standard of Care

Vascular V12. Covered Stent. The New Standard of Care Vascular V12 Covered Stent The New Standard of Care Innovation Novel Thermo-Conformable Covered Stent 316L stainless steel stent completely encapsulated in a proprietary one piece eptfe film cast covering

More information

Chungbuk Regional Cardiovascular Center, Division of Cardiology, Departments of Internal Medicine, Chungbuk National University Hospital Sangmin Kim

Chungbuk Regional Cardiovascular Center, Division of Cardiology, Departments of Internal Medicine, Chungbuk National University Hospital Sangmin Kim Endovascular Procedures for Isolated Common Iliac and Internal Iliac Aneurysm Chungbuk Regional Cardiovascular Center, Division of Cardiology, Departments of Internal Medicine, Chungbuk National University

More information

When to use standard EVAR with EndoAnchors or CHEVAR in short-neck AAAs LINC ASIA 18

When to use standard EVAR with EndoAnchors or CHEVAR in short-neck AAAs LINC ASIA 18 When to use standard EVAR with EndoAnchors or CHEVAR in short-neck AAAs JEAN-PAUL P.M. DE VRIES, DIRECTOR OF VASCULAR SURGERY ST.ANTONIUS HOSPITAL NIEUWEGEIN, THE NETHERLANDS. LINC ASIA-PACIFIC HongKong,

More information

Low profile TEVAR: is it an added value? Michel Bosiers, G. Torsello Münster

Low profile TEVAR: is it an added value? Michel Bosiers, G. Torsello Münster Low profile TEVAR: is it an added value? Michel Bosiers, G. Torsello Münster Disclosure Speaker name:...michel Bosiers... I have the following potential conflicts of interest to report: Consulting Employment

More information

THE THE MORE MORE NATURAL APPROACH TO OPTIMAL FIT

THE THE MORE MORE NATURAL APPROACH TO OPTIMAL FIT THE THE MORE MORE NATURAL APPROACH Natural Approach TO Optimal Fit TO OPTIMAL FIT Conformability without Compromise THE STANDARD IN Conformability AND Designed for flexibility and conformability in tortuous

More information

Clinical trial and real-world outcomes of an endovascular iliac aneurysm repair with the GORE Iliac Branch Endoprosthesis (IBE)

Clinical trial and real-world outcomes of an endovascular iliac aneurysm repair with the GORE Iliac Branch Endoprosthesis (IBE) Clinical trial and real-world outcomes of an endovascular iliac aneurysm repair with the GORE Iliac Branch Endoprosthesis (IBE) Jan MM Heyligers, PhD, FEBVS Consultant Vascular Surgeon The Netherlands

More information

Now that Endoanchors are Approved (and paid for) We have a Durable Solution to Short Necks That s so Easy!

Now that Endoanchors are Approved (and paid for) We have a Durable Solution to Short Necks That s so Easy! Now that Endoanchors are Approved (and paid for) We have a Durable Solution to Short Necks That s so Easy! David H. Deaton, MD Vascular Surgery / University of South Carolina / Palmetto Health Chief Medical

More information

Endologix PowerWeb System EPW?

Endologix PowerWeb System EPW? 13 579 583 2004 Endologix PowerWeb System EPW? Endologix PowerWeb System EPW (AAA) 1993 7 2003 11 AAA 176 155 21 52 897240 120mm 53.5mm EPWEPW 1 2 proximal neck PN 15mm 3 PN 23mm 4 distal neck DN 15mm

More information

Lessons learned from Ch-EVAR for the treatment of. Miltos Matsagkas MD, PhD, FEBVS Professor of Vascular Surgery University of Thessaly

Lessons learned from Ch-EVAR for the treatment of. Miltos Matsagkas MD, PhD, FEBVS Professor of Vascular Surgery University of Thessaly Lessons learned from Ch-EVAR for the treatment of pararenal AAAs Miltos Matsagkas MD, PhD, FEBVS Professor of Vascular Surgery University of Thessaly Ch-EVAR Ch-EVAR = Chimney-EVAR Placement of single

More information

GORE EXCLUDER AAA Endoprosthesis demonstrates long-term durability. Michel Reijnen Rijnstate Hospital Arnhem, The Netherlands

GORE EXCLUDER AAA Endoprosthesis demonstrates long-term durability. Michel Reijnen Rijnstate Hospital Arnhem, The Netherlands GORE EXCLUDER AAA Endoprosthesis demonstrates long-term durability Michel Reijnen Rijnstate Hospital Arnhem, The Netherlands Disclosure Speaker name: Michel Reijnen I have the following potential conflicts

More information

Cook Medical. Zenith Flex AAA Endovascular Graft with Z-Trak Introduction System Physician Training

Cook Medical. Zenith Flex AAA Endovascular Graft with Z-Trak Introduction System Physician Training Cook Medical Zenith Flex AAA Endovascular Graft with Z-Trak Introduction System Physician Training Bifurcated system Proximal suprarenal stent Modular (aortic main body and two iliac legs) Full-thickness,

More information

Indications for use. Contraindications within the United States

Indications for use. Contraindications within the United States Indications for use Indications within the United States The GORE TAG Thoracic Endoprosthesis is intended for endovascular repair of all lesions of the descending thoracic aorta, including: Isolated lesions

More information

Type 1a Endoleak in hostile neck anatomies: Endoanchor can fix it! D. Böckler University Hospital Heidelberg, Germany

Type 1a Endoleak in hostile neck anatomies: Endoanchor can fix it! D. Böckler University Hospital Heidelberg, Germany Type 1a Endoleak in hostile neck anatomies: Endoanchor can fix it! D. Böckler University Hospital Heidelberg, Germany Disclosures Speaker name: Dittmar Böckler I have the following potential conflicts

More information

SANWICH TECHNIQUE TO REDUCE COMPLICATIONS WHEN TREATING BILATERAL INTERNAL ILIAC ARTERY

SANWICH TECHNIQUE TO REDUCE COMPLICATIONS WHEN TREATING BILATERAL INTERNAL ILIAC ARTERY SANWICH TECHNIQUE TO REDUCE COMPLICATIONS WHEN TREATING BILATERAL INTERNAL ILIAC ARTERY TRAN TRA GIANG.MD Interventional cardiovascular department Hanoi Heart Hospital, Hanoi, Viet Nam Nothing to Disclose

More information

Feasibility of aortic neck anatomy for endovascular aneurysm repair in Korean patients with abdominal aortic aneurysm

Feasibility of aortic neck anatomy for endovascular aneurysm repair in Korean patients with abdominal aortic aneurysm LINC 2019 Leipzig, Germany Feasibility of aortic neck anatomy for endovascular aneurysm repair in Korean patients with abdominal aortic aneurysm Deokbi Hwang, Sujin Park, Hyung-Kee Kim, Seung Huh Division

More information

Chimney endovascular aneurysm sealing (ch-evas) for ruptured abdominal aortic aneurysms (AAA) due to type Ia endoleak following failed EVAS

Chimney endovascular aneurysm sealing (ch-evas) for ruptured abdominal aortic aneurysms (AAA) due to type Ia endoleak following failed EVAS Chimney endovascular aneurysm sealing (ch-evas) for ruptured abdominal aortic aneurysms (AAA) due to type Ia endoleak following failed EVAS Saritphat Orrapin MD FRCS (Thailand), Thoetphum Benyakorn, Tunyarat

More information

The Petticoat Technique Managing Type B Dissection with both Early and Long Term Considerations

The Petticoat Technique Managing Type B Dissection with both Early and Long Term Considerations The Petticoat Technique Managing Type B Dissection with both Early and Long Term Considerations Joseph V. Lombardi, MD Professor & Chief, Division of Vascular & Endovascular Surgery Department of Surgery,

More information

Hostile Neck During EVAR, The Role Of Endoanchores

Hostile Neck During EVAR, The Role Of Endoanchores Hostile Neck During EVAR, The Role Of Endoanchores Samer Koussayer, MD, FACS, RVT Prof, Al Faisal University Section Head and consultant Vascular & Endovascular Surgery Division King Faisal Specialist

More information

Obesity, Scaring, Access in EVAR. Kiskinis D, Melas N, Ktenidis K. 1 st Department of Surgery Aristotle University of Thessaloniki, Greece

Obesity, Scaring, Access in EVAR. Kiskinis D, Melas N, Ktenidis K. 1 st Department of Surgery Aristotle University of Thessaloniki, Greece Obesity, Scaring, Access in EVAR Kiskinis D, Melas N, Ktenidis K. 1 st Department of Surgery Aristotle University of Thessaloniki, Greece Obesity Decreased radiolucency (visibility) Max weight load < 160

More information

FLEXIBLE, BALOON EXPANDABLE

FLEXIBLE, BALOON EXPANDABLE EARLY RESULTS OF A CLINICAL TRIAL OF FLEXIBLE, BALOON EXPANDABLE COVERED STENT GRAFT IN ILIAC OCCLUSIVE DISEASE Chris LeCroy Coastal Vascular and Interventional Pensacola, Florida Clinical Trial WL GORE

More information

BC Vascular Day. Contents. November 3, Abdominal Aortic Aneurysm 2 3. Peripheral Arterial Disease 4 6. Deep Venous Thrombosis 7 8

BC Vascular Day. Contents. November 3, Abdominal Aortic Aneurysm 2 3. Peripheral Arterial Disease 4 6. Deep Venous Thrombosis 7 8 BC Vascular Day Contents Abdominal Aortic Aneurysm 2 3 November 3, 2018 Peripheral Arterial Disease 4 6 Deep Venous Thrombosis 7 8 Abdominal Aortic Aneurysm Conservative Management Risk factor modification

More information

Aorfix Pythagoras US Clinical Trial:

Aorfix Pythagoras US Clinical Trial: Overall 1 Year Results from the Aorfix Pythagoras US Clinical Trial: 1 st IDE Study in Highly Angulated 60 133 Aortic Necks Mark Fillinger MD for the PYTHAGORAS Investigators Disclosure Speaker name: Mark

More information

Endoanchor-assisted TEVAR

Endoanchor-assisted TEVAR Endoanchor-assisted TEVAR May 29, 2015 NCVH2015 Grayson H. Wheatley III, MD Director of Aortic and Endovascular Surgery Associate Professor of Surgery Temple University School of Medicine Disclosures Consultant

More information

Technology. The introduction of endovascular aortic repair. cover story

Technology. The introduction of endovascular aortic repair. cover story Infrarenal EVAR Technology Review Steady evolution in device design and delivery has expanded endovascular repair to more patients, but further advancements are integral to this technology s future. By

More information

Development of a Branched LSA Endograft & Ascending Aorta Endograft

Development of a Branched LSA Endograft & Ascending Aorta Endograft Development of a Branched LSA Endograft & Ascending Aorta Endograft Frank R. Arko III, MD Sanger Heart & Vascular Institute Carolinas Medical Center Charlotte, North Carolina, USA Disclosures Proximal

More information

Endovascular Abdominal Repair: Technical Tips to Achieve Best Results and Avoid Disaster

Endovascular Abdominal Repair: Technical Tips to Achieve Best Results and Avoid Disaster Endovascular Abdominal Repair: Technical Tips to Achieve Best Results and Avoid Disaster RICHARD R. HEUSER, MD, FACC, FACP, FESC, FASCI Director Of Cardiology, St. Luke s Medical Center, Phoenix, Arizona

More information

Endovascular Aneurysm Sealing System for Treating Abdominal Aortic Aneurysms: Early Outcomes from a Single Center

Endovascular Aneurysm Sealing System for Treating Abdominal Aortic Aneurysms: Early Outcomes from a Single Center Endovascular Aneurysm Sealing System for Treating Abdominal Aortic Aneurysms: Early Outcomes from a Single Center Thiti Chanmayka MD*, Anucha Ahooja MD**, Chalach Mitprachapranee MD*, Chawalit Wongbhuddha

More information

Off-the-Shelf Devices. Mark A Farber, MD FACS Director, Aortic Center Professor of Radiology and Surgery University of North Carolina

Off-the-Shelf Devices. Mark A Farber, MD FACS Director, Aortic Center Professor of Radiology and Surgery University of North Carolina Off-the-Shelf Devices Mark A Farber, MD FACS Director, Aortic Center Professor of Radiology and Surgery University of North Carolina Disclosures Cook - Research Support, Consultant, Clinical Trials WL

More information

Arch Repair with the Bolton Medical RelayBranch Thoracic Stent-graft system: Multicenter experience

Arch Repair with the Bolton Medical RelayBranch Thoracic Stent-graft system: Multicenter experience Arch Repair with the Bolton Medical RelayBranch Thoracic Stent-graft system: Multicenter experience Joost van Herwaarden, MD, PhD University Medical Center, Utrecht Disclosure I have the following potential

More information