number Done by Corrected by Doctor
|
|
- Jessie Hodge
- 5 years ago
- Views:
Transcription
1 number 19 Done by حسام ابو عوض Corrected by وسيم ابو عبيدة Doctor د.نايف 1 P a g e
2 GAGs and Glycoproteins: GAGs: long, unbranched heteropolysaccharides, made from زunits repeating disaccharide [Acidic sugar Amino sugar]n. n=1,2,3. Amino sugar: is a sugar molecule in which a hydroxyl group has been replaced with an amine group. The amino sugars are usually acetylated (adding an acetyl group to the amine group), it may also be sulphated on carbon 4 or 6 or on a nonacetylated nitrogen. The amino sugar in GAGs is either glucosamine or galactosamine. Acidic sugar: monosaccharides with a carboxyl group. The acidic sugar in GAGs is either glucuronic acid or its c5 epimer, Iduronic acid. Glycoproteins: Made by combining a glucose with an amino acid. This can happen by an O- glycosidic bond (UDP-glucose reacts with threonine, serine or lysine via their OH) or an N-glycosidic bond (UDP-glucose reacts with asparagine via its amide). Glucuronate Pathway: Glucuronic acid can be obtained in small amounts from the diet or degradation of GAGs. Glucuronic acid is an essential component of GAGs and it is required for detoxification reactions of a number of insoluble compounds, such as bilirubin, steroids and several drugs. The active form of glucuronic acid that donates the sugar in GAGs and otherglucuronylating reactions is UDP-glucuronic acid which is produced by oxidation of UDP-glucose. 2 P a g e
3 UDP-glucose is converted to UDP-glucuronate using the UDP-glucose dehydrogenase enzyme, NADH + H+ are produced in the process. The glucuronate from the UDPglucuronate can be donated to many substances and toxins (UDP-glucuronate transferase enzyme is needed) solubilising 3 P a g e
4 them and allowing them to be excreted with urine [E.g. bilirubin is converted to bilirubin diglucuronide, which is soluble and can be excreted. NB: this example is important]. The glucuronate needs to be converted to its UDP form to be activated (like all other sugars). The UDP-glucose participates in many different metabolic pathways as shown:udp-glucose is used in the production of proteoglycans (in addition to the glycoproteins). Antioxidants (From ROS chapter in Mark s book): Oxygen Toxicity Oxygen is a biradical, a molecule that has two unpaired electrons in separate orbitals. The oxygen superoxide and the hydroxyl radical are free radicals, while the H₂O₂despite being a ROS, is not a free radical (does not contain free unpaired electron). 4 P a g e
5 90% of the O₂ we get is used in the aerobic respiration. The other 10% is divided: 5-7% is used in other oxidation-reduction reactions, the oxygenase enzymes (monooxygenases and dioxygenases, refer to the previous sheet). 3-5% is used in the production of ROS from oxygen, this amount is useful for protective mechanism in the body against many microbes, but this amount could increase in some inflammatory responses and harm the body. Examples of ROS: OCL, H₂O₂, OH and the superoxide free radical (O₂ ) The ROS can cause atherosclerosis, respiratory diseases, Parkinson s disease, cancer, diabetes, liver damage, motor neuron damage and appear to have a role in aging. The ROS can be behind complications from a disease. (The WBC s produce them to destroy some pathogens but then the ROS themselves can cause damage). They can damage proteins, lipids, nucleic acids and carbohydrates. The structures most prone to damage are the ones containing proline, histidine, arginine, cysteine and methionine. Oxygen in complex 4 of the oxidative phosphorylation, in the process to produce water, produces many intermediates that are actually ROS. Side note: electrons cannot escape from complex 4 because they are well contained by the electron acceptors there and the iron-sulphur centres. Fenton Reaction H₂O₂ is changed to OH and OH (most potent ROS). This reaction occurs through oxidising Fe²+ (or Cu+) to Feᵌ+ (or Cu²+). (This reaction is very important). Any free iron can cause problems because of this reaction (free radical is produced) so it is well secured by the body (ferritin stores iron, if iron amountsexceedferritin s storage capacity it changes to hemosiderin to be able to store more), but if its intake is too high then there will be some free iron [high iron in the blood is often seen with blood transfusion as iron is preserved in the blood so the patients are given iron chelators (make iron soluble)]. Side Note: Most young females have lower iron intake than needed while young males often have what is enough for them. Females need iron more than males. 5 P a g e
6 Haber-Weiss Reaction O₂ reacts with H₂O₂ (also H+ is involved in the process) to produce O₂, H₂O and OH. ROS and Lipids The ROS can damage membranes and organelles. This means that there will be gaps in the membrane (lipids are peroxidised, mainly poly-unsaturated ones. Proteins and DNA are also badly affected) allowing ions and water to enter causing cellular swelling. Following we go through the reaction of the ROS with the Poly-unsaturated Fatty-acids (PUFA). So, as we see a chain reaction begins in which a new free radical is produced each time. The LOOH (lipidhydro-peroxide) produced by the reaction above is degraded to Malondialdehyde (MDA) and a lipid peroxide. The MDA goes to the blood then is excreted with urine. The MDA concentration/amount in the urine is used in the laboratory as a marker to predict the amount of ROS present in the body in many chronic disease. (Other markers from other molecules are present, but this is the one tested for most often). There are some defensive mechanisms against ROS in the body like the SOD (Superoxide-dismutase) which converts the superoxide to hydrogen-peroxide 6 P a g e
7 which is then converted by catalase (only for inorganic hydrogen peroxide) to water and oxygen or reduced to water by the oxidation of glutathione (glutathione peroxidase enzyme is used). For glutathione to be reduced back (so that it can be used again) the enzyme glutathione reductase (which needs NADPH to function) is required. Other endogenous antioxidants include: melatonin, bilirubin, lipoic acid and ubiquinone. (They are sold as supplements in pharmacies, using these supplements is advised for elderly because they have a higher concentration of ROS in their bodies). Also, it is important to get some anti-oxidants from your diet (vitamin E, vitamin C and β-carotenes). In addition, there are some repair mechanisms in the body for the damaged substances (DNA, amino acids and fatty acids). An extremely important point to note is that our body doesn t let itself prone to attacks and damages easily. Wherever the ROS are needed you would notice that they are stored in their own vesicles (peroxisomes) with many antioxidants available for use within that cell (this is called compartmentation). This is often seen in the liver, adrenal glands and kidneys. Other Dietary Antioxidants Flavonoids These are polyphenol compounds, which contain many phenol rings in their structures like the molecule quercetin. You can obtain these flavonoids from many different dietary sources like green tea and chocolate. These flavonoids have the ability to reduce the production of ROS like superoxide ion by inhibiting the xanthine oxidase enzyme (this enzyme produces ROS). They also act as free radical scavengers (they react with the free radical ending its problem). They have the ability to maintain vitamin E and can chelate (a specific chemical process) iron and copper. [Extra: some types of flavonoids (between brackets is a source of that flavonoid type): Catechins (strawberries), Kaempferol (apples), quercetin (beans) and epicatechins (cocoa)]. 7 P a g e
8 Vitamin Antioxidants Vitamin E: its only physiological job in the body is to remove the free radical state from substances. It does this by donating an electron to a free radical molecule (no longer becomes a radical) (vitamin E becomes a radical) then reacting with another free radical (both radicals react, vitamin E and the 2 nd free radical molecule) neutralising its effect.the molecule α-tocopherol is vitamin E. The reaction is shown in this diagram: Vitamin C: it can accept an electron from the superoxide ion, hydrogen peroxide, HOCL and the lipid peroxyl radicals. It can also return the reduced vitamin E to its active form. Carotenoids: these also accept an electron from the lipid peroxyl radicals. The diagram shows the action of vitamin C and carotenoids: (The doctor never mentioned the details seen in this image, but they are in the slides, so they were added to be on the safe side). 8 P a g e
Reactive Oxygen species ROS + Anti-oxidants. Dr. Naif Karadsheh
Reactive Oxygen species ROS + Anti-oxidants Dr. Naif Karadsheh Oxygen Toxicity & Free Radicals Biradical O 2 Radical O 2 Non-Radical Radical H 2 O 2 OH ROS O 2 Metabolism and Toxicity O 2 Consumption >90%
More informationLujain Hamdan. Faisal Nimri
20 Lujain Hamdan Faisal Nimri...... Sources of NADPH [ The pentose phosphate pathway is the primary source of the NADPH and is the only source in RBC.] Cytosolic conversion of oxaloacetate to pyruvate
More informationnumber Done by Corrected by Doctor
number 18 Done by Mahmoud Harbi Corrected by حسام أبو عوض Doctor Nayef Karadsheh Sources of Reactive Oxygen Species (ROS) 1 P a g e 1- Oxidases: there are some that produce hydrogen peroxide (H₂O₂) 2-
More informationnumber Done by Corrected by Doctor Nayef Karadsheh
number 17 Done by Abdulrahman Alhanbali Corrected by Lara Abdallat Doctor Nayef Karadsheh 1 P a g e Pentose Phosphate Pathway (PPP) Or Hexose Monophosphate Shunt In this lecture We will talk about the
More informationBiologic Oxidation BIOMEDICAL IMPORTAN
Biologic Oxidation BIOMEDICAL IMPORTAN Chemically, oxidation is defined as the removal of electrons and reduction as the gain of electrons. Thus, oxidation is always accompanied by reduction of an electron
More informationMoh Tarek + Faisal Massad. Tala Saleh ... Naif
19 Moh Tarek + Faisal Massad Tala Saleh... Naif Last lecture we ve talked about the main antioxidant system which are the enzymes found in our body, mainly: 1. Glutathione peroxidase 2. Super oxide dismutase(sod)
More informationMetabolism of xenobiotics FM CHE 5-6
Metabolism of xenobiotics FM 3.5-10 CHE 5-6 Metabolism of xenobiotics Also called:! Biotransformation, or detoxification Primary metabolism secondary metabolism Goal: To make use of a compound or to facilitate
More informationLipid Oxidation and its Implications to Food Quality and Human Health. Dong Uk Ahn Animal Science Department Iowa State University
Lipid Oxidation and its Implications to Food Quality and Human Health Dong Uk Ahn Animal Science Department Iowa State University Introduction Process of Lipid Oxidation Free Radicals and Reactive Oxygen
More informationFree Radicals in Biology and Medicine
Free Radicals in Biology and Medicine 0 \ Second Edition BARRY HALLIWELL Professor of Medical Biochemistry, University of London King's College and JOHN M.C. GUTTERIDGE Senior Scientist, National Institute
More informationGlycosaminoglycans: Anionic polysaccharide chains made of repeating disaccharide units
Glycosaminoglycans: Anionic polysaccharide chains made of repeating disaccharide units Glycosaminoglycans present on the animal cell surface and in the extracellular matrix. Glycoseaminoglycans (mucopolysaccharides)
More information~PENTOSE PHOSPHATE PATHWAY~ DR. A. TARAB DEPT. OF BIOCHEMISTRY HKMU
~PENTOSE PHOSPHATE PATHWAY~ DR. A. TARAB DEPT. OF BIOCHEMISTRY HKMU OVERVIEW The pentose phosphate pathway (also called the hexose monophosphate shunt, or 6- phosphogluconate pathway) occurs in the cytosol
More informationGlycosaminoglycans, Proteoglycans, and Glycoproteins
Glycosaminoglycans, Proteoglycans, and Glycoproteins Presented by Dr. Mohammad Saadeh The requirements for the Pharmaceutical Biochemistry I Philadelphia University Faculty of pharmacy I. OVERVIEW OF GLYCOSAMINOGLYCANS
More informationMahaAbuAjamieh. BahaaNajjar. MamoonAhram
7 MahaAbuAjamieh BahaaNajjar MamoonAhram Carbohydrates (saccharides) can be classified into these main categories: 1. Monosaccharides, they are simplesugars (the simplest units), such as glucose, galactose
More informationnumber Done by Corrected by Doctor Nayef Karadsheh
number 16 Done Huda shaheen by Corrected by حسام أبو عوض Doctor Nayef Karadsheh 1 In the previous lecture, we talked about glycogen metabolism and regulation. In this sheet we will talk about the metabolism
More information-can be classified by the number of sugars that constitute the molecules: -how to differentiate between glucose and galactose?
Carbohydrates (Also called: saccharides) -can be classified by the number of sugars that constitute the molecules: 1- monosaccharides: -General formula: (CH2O)n -Contain one sugar molecule -Contain two
More informationBIOL 158: BIOLOGICAL CHEMISTRY II
BIOL 158: BIOLOGICAL CHEMISTRY II Lecture 5: Vitamins and Coenzymes Lecturer: Christopher Larbie, PhD Introduction Cofactors bind to the active site and assist in the reaction mechanism Apoenzyme is an
More informationNutrients. Chapter 25 Nutrition, Metabolism, Temperature Regulation
Chapter 25 Nutrition, Metabolism, Temperature Regulation 25-1 Nutrients Chemicals used by body to produce energy, provide building blocks or function in other chemical reactions Classes Carbohydrates,
More informationChapter 2 Part 3: Organic and Inorganic Compounds
Chapter 2 Part 3: Organic and Inorganic Compounds Objectives: 1) List the major groups of inorganic chemicals common in cells. 2) Describe the functions of various types of inorganic chemicals in cells.
More informationPentose Phosphate Pathway. Dr. Abir Alghanouchi Biochemistry department Sciences college
Pentose Phosphate Pathway Dr. Abir Alghanouchi Biochemistry department Sciences college The pentose phosphate pathway is an alternate route for the oxidation of glucose where ATP (energy) is neither produced
More informationCarbohydrates. Learning Objective
, one of the four major classes of biomolecules, are aldehyde or ketone compounds with multiple hydroxyl groups. They function as energy stores, metabolic intermediates and important fuels for the body.
More informationSpeaker: Paul De Smet. Thursday June 4th 2015
Speaker: Paul De Smet Thursday June 4th 2015 Your logo Stress Support: the nutritional answer to stress, infection and disease Thursday June 4th 2015 Table of content Stress Support: the nutritional answer
More informationProteins consist in whole or large part of amino acids. Simple proteins consist only of amino acids.
Today we begin our discussion of the structure and properties of proteins. Proteins consist in whole or large part of amino acids. Simple proteins consist only of amino acids. Conjugated proteins contain
More informationLecture Series 2 Macromolecules: Their Structure and Function
Lecture Series 2 Macromolecules: Their Structure and Function Reading Assignments Read Chapter 4 (Protein structure & Function) Biological Substances found in Living Tissues The big four in terms of macromolecules
More informationA. Lipids: Water-Insoluble Molecules
Biological Substances found in Living Tissues Lecture Series 3 Macromolecules: Their Structure and Function A. Lipids: Water-Insoluble Lipids can form large biological molecules, but these aggregations
More informationLecture Series 2 Macromolecules: Their Structure and Function
Lecture Series 2 Macromolecules: Their Structure and Function Reading Assignments Read Chapter 4 (Protein structure & Function) Biological Substances found in Living Tissues The big four in terms of macromolecules
More informationDigestive and Excretory Systems
Digestive and Excretory Systems Homeostasis Q: How are the materials that enter and leave your body related to the processes that maintain homeostasis? 30.1 How is the human body organized and regulated?
More informationLecture Series 2 Macromolecules: Their Structure and Function
Lecture Series 2 Macromolecules: Their Structure and Function Reading Assignments Read Chapter 4 (Protein structure & Function) Biological Substances found in Living Tissues The big four in terms of macromolecules
More informationMetabolism. Chapter 5. Catabolism Drives Anabolism 8/29/11. Complete Catabolism of Glucose
8/29/11 Metabolism Chapter 5 All of the reactions in the body that require energy transfer. Can be divided into: Cell Respiration and Metabolism Anabolism: requires the input of energy to synthesize large
More information2 3 Carbon Compounds (Macromolecules)
2 3 Carbon Compounds (Macromolecules) Slide 1 of 37 Organic Chemistry Organic chemistry is the study of all compounds that contain bonds between carbon atoms. Slide 2 of 37 Carbon Living organisms are
More informationImportant reactions of lipids
Taif University College of Medicine Preparatory Year Students Medical chemistry (2) Part II (Lipids) week 4 lectures 1435-36 Important reactions of lipids Lectures outlines Definition and importance of
More informationBIOASTIN Bioastin is product that contains 4 mg astaxantin and 50 i.e. vitamin E (α-tocopherol) per tabl.. Carotenoids are family of around 700 substa
INTRODUCTION In 1956 Rebecca Gerchman and Daniel Gilbert detected toxic effect of superoxid on aerobs. Till today there are identificated many free radicals. Their toxic effect is registrated in more than
More informationSheet #10 Dr. Mamoun Ahram Sec 1,2,3 15/07/2014. Carbohydrates 2
Carbohydrates 2 A study Guide: Kindly,refer to the slide number,look at the structures and read the sheet notes well,most of the slides content besides all what the doctor said are mentioned here,good
More informationThe. Crash Course. Basically, almost all living things are made up of these 4 Elements: - Carbon (C) - Nitrogen (N) - Hydrogen (H) - Oxygen (O)
The Biochemistry Crash Course Basically, almost all living things are made up of these 4 Elements: - Carbon (C) - Nitrogen (N) - Hydrogen (H) - Oxygen (O) This exercise is designed to familiarize you with
More informationBiology. Slide 1 of 37. End Show. Copyright Pearson Prentice Hall
Biology 1 of 37 2 of 37 The Chemistry of Carbon The Chemistry of Carbon Organic chemistry is the study of all compounds that contain bonds between carbon atoms. 3 of 37 Macromolecules Macromolecules Macromolecules
More informationCarbohydrates. Monosaccharides
Carbohydrates Carbohydrates (also called saccharides) are molecular compounds made from just three elements: carbon, hydrogen and oxygen. Monosaccharides (e.g. glucose) and disaccharides (e.g. sucrose)
More informationNOTE: For studying for the final, you only have to worry about those with an asterix (*)
NOTE: For studying for the final, you only have to worry about those with an asterix (*) (*)1. An organic compound is one that: a. contains carbon b. is slightly acidic c. forms long chains d. is soluble
More informationState of the art ingredients fast friendly service
ALPHA-LIPOIC ACID An Efficient Antioxidant α-lipoic acid also known as thioctic acid, plays an important role in metabolic processes. It functions as a co-factor for a number of key enzymes that help in
More informationA. Incorrect! No, this is not the description of this type of molecule. B. Incorrect! No, this is not the description of this type of molecule.
Biochemistry - Problem Drill 08: Carbohydrates No. 1 of 10 1. have one aldehyde (-CHO) or one keto (-C=O) group and many hydroxyl (-OH) groups. (A) Amino acids (B) Proteins (C) Nucleic Acids (D) Carbohydrates
More informationBiochemistry - I. Prof. S. Dasgupta Department of Chemistry Indian Institute of Technology, Kharagpur Lecture 1 Amino Acids I
Biochemistry - I Prof. S. Dasgupta Department of Chemistry Indian Institute of Technology, Kharagpur Lecture 1 Amino Acids I Hello, welcome to the course Biochemistry 1 conducted by me Dr. S Dasgupta,
More informationMid Term Test- Template Questions
Mid Term Test- Template Questions Name : ID : Time: Date: Total points: 100 Instructions: 1. Only 20 questions from Section I and II, 10 questions from Section III will be counted for grading. 2. Try to
More informationAbdullah zurayqat. Bahaa Najjar. Mamoun Ahram
9 Abdullah zurayqat Bahaa Najjar Mamoun Ahram Polysaccharides Polysaccharides Definition and Structure [Greek poly = many; sacchar = sugar] are complex carbohydrates, composed of 10 to up to several thousand
More informationPublished on Second Faculty of Medicine, Charles University (http://www.lf2.cuni.cz )
Published on Second Faculty of Medicine, Charles University (http://www.lf2.cuni.cz ) Biochemistry Submitted by Marie Havlová on 8. February 2012-0:00 Syllabus of Biochemistry Mechanisms of enzyme catalysis.
More informationBIOCHEMISTRY NOTES PT. 3 FOUR MAIN TYPES OF ORGANIC MOLECULES THAT MAKE UP LIVING THINGS
BIOCHEMISTRY NOTES PT. 3 FOUR MAIN TYPES OF ORGANIC MOLECULES THAT MAKE UP LIVING THINGS 1. 2. 3. 4. CARBOHYDRATES LIPIDS (fats) PROTEINS NUCLEIC ACIDS We call these four main types of carbon- based molecules
More informationDetails of Organic Chem! Date. Carbon & The Molecular Diversity of Life & The Structure & Function of Macromolecules
Details of Organic Chem! Date Carbon & The Molecular Diversity of Life & The Structure & Function of Macromolecules Functional Groups, I Attachments that replace one or more of the hydrogens bonded to
More informationThe Structure and Function of Macromolecules
The Structure and Function of Macromolecules Macromolecules are polymers Polymer long molecule consisting of many similar building blocks. Monomer the small building block molecules. Carbohydrates, proteins
More informationNBCE Mock Board Questions Biochemistry
1. Fluid mosaic describes. A. Tertiary structure of proteins B. Ribosomal subunits C. DNA structure D. Plasma membrane structure NBCE Mock Board Questions Biochemistry 2. Where in the cell does beta oxidation
More informationCh 07. Microbial Metabolism
Ch 07 Microbial Metabolism SLOs Differentiate between metabolism, catabolism, and anabolism. Fully describe the structure and function of enzymes. Differentiate between constitutive and regulated enzymes.
More informationObjectives. Carbon Bonding. Carbon Bonding, continued. Carbon Bonding
Biochemistry Table of Contents Objectives Distinguish between organic and inorganic compounds. Explain the importance of carbon bonding in biological molecules. Identify functional groups in biological
More informationChapter 3. Table of Contents. Section 1 Carbon Compounds. Section 2 Molecules of Life. Biochemistry
Biochemistry Table of Contents Section 1 Carbon Compounds Section 2 Molecules of Life Section 1 Carbon Compounds Objectives Distinguish between organic and inorganic compounds. Explain the importance of
More informationChemical Formulas. Chemical Formula CH 3 COCHCHOCHClCHNH Lewis Dot Structure
Biochemistry . Chemical Formulas A chemical formula represents the chemical makeup of a compound. It shows the numbers and kinds of atoms present in a compound. It is a kind of shorthand that scientists
More informationAntioxidant Products
Antioxidant Products Introduction Introduction Antioxidant Total Antioxidant Status (TAS) Ransel Ransod Glutathione Reductase Antioxidants help defend living organisms against free radical attack. Many
More informationTopic 3.1 Nutrients. - Lipids are an essential part of the and are a part of cell in the body.
Name: Topic 3.1 Nutrients Date: IB SEHS 3.1.1. List the macronutrients and micronutrients Macronutrients: - lipid (fat) - carbohydrate - protein - water (says the book) Micronutrients: - vitamins - minerals
More informationFarah Al-Khaled. Razi Kittaneh. Mohammad Omari
7 Farah Al-Khaled Razi Kittaneh Mohammad Omari Dr. Mamoun Ahram In this lecture we are going to talk about modified sugars. Remember: The Fischer projection can be turned into a ring structure (which is
More information6/15/2015. Biological Molecules. Outline. Organic Compounds. Organic Compounds - definition Functional Groups Biological Molecules. What is organic?
Biological Molecules Biology 105 Lecture 3 Reading: Chapter 2 (pages 29 39) Outline Organic Compounds - definition Functional Groups Biological Molecules Carbohydrates Lipids Amino Acids and Proteins Nucleotides
More informationCONVERSION OF AMINO ACIDS TO SPECIALIZED PRODUCTS DR. A. TARAB DEPT. OF BIOCHEMISTRY HKMU
CONVERSION OF AMINO ACIDS TO SPECIALIZED PRODUCTS DR. A. TARAB DEPT. OF BIOCHEMISTRY HKMU In addition to serving as building blocks for proteins, amino acids are precursors of many nitrogen-containing
More informationAging and nutrition 03/11/2012. Why do people age? Oxidative stress and damage
Aging and nutrition % of elderly people in Canadian population is increasing more than for other age groups within the elderly age group there is great variability in terms health, metabolism, physical
More information2.1.1 Biological Molecules
2.1.1 Biological Molecules Relevant Past Paper Questions Paper Question Specification point(s) tested 2013 January 4 parts c and d p r 2013 January 6 except part c j k m n o 2012 June 1 part ci d e f g
More informationTopic 3: Molecular Biology
Topic 3: Molecular Biology 3.2 Carbohydrates and Lipids Essen=al Understanding: Carbon, hydrogen and oxygen are used to supply and store energy. Carbohydrates CARBOHYDRATES CHO sugars Primarily consist
More informationBiology 12 - Biochemistry Practice Exam
Biology 12 - Biochemistry Practice Exam Name: Water: 1. The bond between water molecules is a (n) a. ionic bond b. covalent bond c. polar covalent bond d. hydrogen bond 2. The water properties: good solvent,
More informationBiomolecules. Presented by Amelia McCutcheon
Biomolecules Presented by Amelia McCutcheon Fats Carbohydrates Proteins Vitamins Fats Also known as lipids Fats are solids (high mel=ng point) ils are liquids (low mel=ng point) Mainly consist of Carbon
More informationActivity: Biologically Important Molecules
Activity: Biologically Important Molecules AP Biology Introduction We have already seen in our study of biochemistry that the molecules that comprise living things are carbon-based, and that they are thought
More informationAssignment #1: Biological Molecules & the Chemistry of Life
Assignment #1: Biological Molecules & the Chemistry of Life A. Important Inorganic Molecules Water 1. Explain why water is considered a polar molecule. The partial negative charge of the oxygen and the
More informationWallington County Grammar School
Wallington County Grammar School Y11 to Lower Sixth Bridging Work Subject: Subject Leader to direct questions to (email enquiries@wcgs.org.uk): Estimated hours of work needed to complete this work successfully:
More informationWHY IS THIS IMPORTANT?
CHAPTER 2 FUNDAMENTAL CHEMISTRY FOR MICROBIOLOGY WHY IS THIS IMPORTANT? An understanding of chemistry is essential to understand cellular structure and function, which are paramount for your understanding
More informationPROTEIN. By: Shamsul Azahari Zainal Badari Department of Resource Management and Consumer Studies Faculty of Human Ecology UPM
PROTEIN By: Shamsul Azahari Zainal Badari Department of Resource Management and Consumer Studies Faculty of Human Ecology UPM OBJECTIVES OF THE LECTURE By the end of this lecture, student can: Define
More informationMolecules of Life. Carbohydrates Lipids Proteins Nucleic Acids
Molecules of Life Carbohydrates Lipids Proteins Nucleic Acids Molecules of Life All living things are composed of the following basic elements: Carbon Hydrogen Oxygen Nitrogen Phosphorous Sulfur Remember
More informationThe Structure and Function of Biomolecules
The Structure and Function of Biomolecules The student is expected to: 9A compare the structures and functions of different types of biomolecules, including carbohydrates, lipids, proteins, and nucleic
More information(65 pts.) 27. (10 pts.) 28. (15 pts.) 29. (10 pts.) TOTAL (100 points) Moorpark College Chemistry 11 Spring Instructor: Professor Gopal
Moorpark College Chemistry 11 Spring 2012 Instructor: Professor Gopal Examination # 5: Section Five May 1, 2012 Name: (print) GOOD LUCK! Directions: Make sure your examination contains TWELVE total pages
More informationCellular Respiration- -conversion of stored energy in glucose to usable energy for the cell -energy in cells is stored in the form of ATP
Cellular Respiration Notes Chapter 7 How Cells Make ATP Energy Releasing Pathways Cellular Respiration- -conversion of stored energy in glucose to usable energy for the cell -energy in cells is stored
More informationPhotosynthesis Digestion Respiration. ., proteins. ... Glucose,.., fatty acids and glycerol, respectively.
BIOMOLECULES Dear Reader In the previous chapter you have read about DNA present in the chromosomes. It is one of the many organic chemical compounds present in all living organisms. The organic compounds
More informationBiochemistry Name: Practice Questions
Name: Practice Questions 1. Carbohydrate molecules A and B come in contact with the cell membrane of the same cell. Molecule A passes through the membrane readily, but molecule B does not. It is most likely
More information1. Which of the following contributes to the tertiary structure of proteins?
Chemistry 11 Spring 2009 Examination #5 ANSWER KEY For the first portion of this exam, select the best answer choice for the questions below and mark the answers on your scantron. Then answer the free
More informationA deficiency of biotin, commonly seen in alcoholics, can cause neurological symptoms
Water-soluble vitamins Vitamin deficiencies Metabolism General Diseases etc. A deficiency of biotin, commonly seen in alcoholics, can cause neurological symptoms Levels of folate are particularly low in
More information- Spontaneous hemorrhaging increase
MEDCHEM 562-2014 Fat Soluble Vitamins Problem Set 1. Fill out the blanks in the table below. Vitamin Physiological Function Deficiency symptoms Toxicity A -Vision -Cell Differentiation -Inhibition of Cell
More information2 3 Carbon Compounds Slide 1 of 37
1 of 37 The Chemistry of Carbon The Chemistry of Carbon Organic chemistry is the study of all compounds that contain bonds between carbon atoms. Carbon atoms have four valence electrons that can join with
More informationObjective: You will be able to explain how the subcomponents of
Objective: You will be able to explain how the subcomponents of nucleic acids determine the properties of that polymer. Do Now: Read the first two paragraphs from enduring understanding 4.A Essential knowledge:
More informationHompes Method Lesson 29 Organic Acids Part Three
Hompes Method Lesson 29 Organic Acids Part Three Health for the People Ltd not for reuse without expressed permission Organic Acids - Review Fats, carbohydrates, and amino acids are converted into carboxylic
More information3. Hydrogen bonds form between which atoms? Between an electropositive hydrogen and an electronegative N, O or F.
Chemistry of Life Answers 1. Differentiate between an ionic and covalent bond. Provide an example for each. Ionic: occurs between metals and non-metals, e.g., NaCl Covalent: occurs between two non-metals;
More informationMolecules of Life. Chapter 22. Great Idea: A cell s major parts are constructed from a few simple molecular building blocks 1
Molecules of Life Chapter 22 Great Idea: A cell s major parts are constructed from a few simple molecular building blocks 1 Chapter Outline Organic Molecules Organic Chemistry Proteins: The Workhorses
More informationUnit 3: Chemistry of Life Mr. Nagel Meade High School
Unit 3: Chemistry of Life Mr. Nagel Meade High School IB Syllabus Statements 3.2.1 Distinguish between organic and inorganic compounds. 3.2.2 Identify amino acids, glucose, ribose and fatty acids from
More informationEnzymes what are they?
Topic 11 (ch8) Microbial Metabolism Topics Metabolism Energy Pathways Biosynthesis 1 Catabolism Anabolism Enzymes Metabolism 2 Metabolic balancing act Catabolism Enzymes involved in breakdown of complex
More informationHW #9: 21.36, 21.52, 21.54, 21.56, 21.62, 21.68, 21.70, 21.76, 21.82, 21.88, 21.94, Carbohydrates
Chemistry 131 Lectures 16 & 17: Carbohydrates Chapter 21 in McMurry, Ballantine, et. al. 7 th edition 05/24/18, 05/25/18 W #9: 21.36, 21.52, 21.54, 21.56, 21.62, 21.68, 21.70, 21.76, 21.82, 21.88, 21.94,
More informationMay 21 st, 2008 Biochemistry Recitation
May 21 st, 2008 Biochemistry Recitation MBioS 303 Summer 2008 Outline Carbohydrate basics Aldoses vs. ketoses L and D configurations and anomers Glycosidic bonds, disaccharides Polysaccharides Storage:
More informationAmino Acid Metabolism
Amino Acid Metabolism Last Week Most of the Animal Kingdom = Lazy - Most higher organisms in the animal kindom don t bother to make all of the amino acids. - Instead, we eat things that make the essential
More informationTEST NAME:Cells and Health TEST ID: GRADE:08 - Eighth Grade SUBJECT:Life and Physical Sciences TEST CATEGORY: School Assessment
TEST NAME:Cells and Health TEST ID:1326431 GRADE:08 - Eighth Grade SUBJECT:Life and Physical Sciences TEST CATEGORY: School Assessment Cells and Health Page 1 of 15 Student: Class: Date: 1. Which best
More informationLesson 2. Biological Molecules. Introduction to Life Processes - SCI 102 1
Lesson 2 Biological Molecules Introduction to Life Processes - SCI 102 1 Carbon in Biological Molecules Organic molecules contain carbon (C) and hydrogen (H) Example: glucose (C 6 H 12 O 6 ) Inorganic
More informationBiological Chemistry. Is biochemistry fun? - Find it out!
Biological Chemistry Is biochemistry fun? - Find it out! 1. Key concepts Outline 2. Condensation and Hydrolysis Reactions 3. Carbohydrates 4. Lipids 5. Proteins 6. Nucleic Acids Key Concepts: 1. Organic
More informationTopic 4 - #2 Carbohydrates Topic 2
Topic 4 - #2 Carbohydrates Topic 2 Biologically Important Monosaccharide Derivatives There are a large number of monosaccharide derivatives. A variety of chemical and enzymatic reactions produce these
More information9/6/2011. Amino Acids. C α. Nonpolar, aliphatic R groups
Amino Acids Side chains (R groups) vary in: size shape charge hydrogen-bonding capacity hydrophobic character chemical reactivity C α Nonpolar, aliphatic R groups Glycine (Gly, G) Alanine (Ala, A) Valine
More informationMacro molecule = is all the reactions that take place in cells, the sum of all chemical reactions that occur within a living organism Anabolism:
Macromolecule Macro molecule = molecule that is built up from smaller units The smaller single subunits that make up macromolecules are known as Joining two or more single units together form a M is all
More informationMacromolecules. The four groups of biomolecules or macromolecules found in living things which are essential to life are: 1. PROTEINS 1.
Macromolecules The four groups of biomolecules or macromolecules found in living things which are essential to life are: 1. PROTEINS 1. CARBOHYDRATES 1. LIPIDS 1. NUCLEIC ACIDS Carbon Compounds All compounds
More informationBiological molecules
Biological molecules 04-04-16 Announcements Your lab report 1 is due now Quiz 1 is on Wednesday at the beginning of class, so don t be late Review Macromolecues are large molecules necessary for life made
More informationBio 12 Chapter 2 Test Review
Bio 12 Chapter 2 Test Review 1.Know the difference between ionic and covalent bonds In order to complete outer shells in electrons bonds can be Ionic; one atom donates or receives electrons Covalent; atoms
More informationnumber Done by Corrected by Doctor Nafeth Abu Tarboush
number 7 Done by حسام أبو عوض Corrected by Shahd Alqudah Doctor Nafeth Abu Tarboush 1 P a g e As we have studied before, in the fourth reaction of the Krebs cycle, α- ketoglutarate is converted into Succinyl-CoA
More informationBiological Molecules Ch 2: Chemistry Comes to Life
Outline Biological Molecules Ch 2: Chemistry Comes to Life Biol 105 Lecture 3 Reading Chapter 2 (pages 31 39) Biological Molecules Carbohydrates Lipids Amino acids and Proteins Nucleotides and Nucleic
More informationAmino acids. You are required to know and identify the 20 amino acids : their names, 3 letter abbreviations and their structures.
Amino acids You are required to know and identify the 20 amino acids : their names, 3 letter abbreviations and their structures. If you wanna make any classification in the world, you have to find what
More information1.3.1 Function of Food. Why do we need food?
1.3.1 Function of Food Why do we need food? Need to know The Function of Food Three reasons for requiring food 2 Food is needed for: 1.Energy 2.Growth of new cells and Repair of existing cells, tissues,
More informationMetabolism. Chapter 8 Microbial Metabolism. Metabolic balancing act. Catabolism Anabolism Enzymes. Topics. Metabolism Energy Pathways Biosynthesis
Chapter 8 Microbial Metabolism Topics Metabolism Energy Pathways Biosynthesis Catabolism Anabolism Enzymes Metabolism 1 2 Metabolic balancing act Catabolism and anabolism simple model Catabolism Enzymes
More information