SAFETY DATA SHEET. Netanya, , Israel

Transcription

1 OF THE EFAL CHEMICAL INDUSTRIES LTD GROUP 8, Hamlacha St, POB 823 Netanya 42293, Israel Web site: wwwefal com SAFETY DATA SHEET Efal-Agri PO Box 823, In case of emergency, Call Netanya, , Israel PRODUCT IDENTIFICATION UNIK PLANT GROWTH REGULATOR Product Name : Signal Word : Caution Active Ingredient (%) : Uniconazole: 5% CAS No : Chemical Name : [(E)-(+)-(S)--(4-chlorophenyl)-4,4-dimethyl-2-),2,4-triazol--yl)-pent- -ene-3-0l] Chemical Class A triazole plant growth regulator 2 COMPOSITION / INFORMATION ON INGREDIENTS Ingredient Weight Exposure Limit Ref Uniconazole * 5% None Propylene Glycol 5% None Other Ingredients** 90% None * Active ingredient ** Other ingredients other than the active ingredient contained in this product are maintained as trade secrets Some of these may be hazardous, but their identity is withheld because they are considered trade secrets The hazards associated with the other ingredients are addressed in this document Specific information on other ingredients for the management of exposures, spills, or safety assessments can be obtained by a treating physician or nurse by calling 3 HAZARDS IDENTIFICATION EMERGENCY OVERVIEW CAUTION : - CAUSES EYE IRRITATION - AVOID CONTACT WITH EYES, SKIN AND CLOTHING - KEEP OUT OF REACH OF CHILDREN POTENTIAL HEALTH EFFECTS Acute Toxicty (Primary Routes of Exposure) Eye : This product is expected to cause brief and/or minor eye irritation The degree of injury will depend on the amount and duration of contact and the speed and thoroughness of the first aid treatment The expected adverse health effects resulting from an exposure may include redness and possible swelling Skin : This product is expected to cause brief and/or minor irritation The degree of injury will depend on the amount and duration of contact and the speed and thoroughness of the first aid treatment The expected adverse health effects resulting from an exposure may include redness and possibly some minor swelling This product is not expected to cause allergic skin reactions PRODUCT NAME : UNIK PLANT GROWTH REGULATOR Page :

2 OF THE EFAL CHEMICAL INDUSTRIES LTD GROUP 8, Hamlacha St, POB 823 Netanya 42293, Israel Web site: wwwefal com This product has been shown to be minimally toxic when absorbed through the skin The degree of injury will depend on the amount of material injected and the speed and thoroughness of the first aid treatment Ingestion : This product has been shown to be minimally toxic when injested The degree of injury will depend on the amount of material ingested and the speed and thoroughness of the first aid treatment Inhalation : This product has been shown to be minimally toxic when inhaled The degree of injury will depend on the amount of material inhaled and the speed and thoroughness of the first aid treatment Chronic Toxicity (including Cancer) : See Section Teratology (Birth Defects) Information : See Section Reproduction Information : See Section Potentially Aggravated Condition : Individuals with preexisting diseases of the liver or kidney may have increased susceptibility of the toxicity of excessive exposures For complete discussion of the toxicology data from which this evaluation was made, refer to Section For regulatory information refer to Section 5 4 FIRST AID MEASURES Have the product container, label or Material Safety Data Sheet with you when calling a poison control center or doctor, or going for treatment Ingestion : If swallowed, call a poison control center or doctor immediately for treatment advice Have the person sip -2 glasses of water or milk if able to swallow Do not include vomiting unless told to do so after calling a poison control center or doctor Do not give anything by mouth to an unconscious person Eye Contract : If in eyes : Hold eye open and rinse slowly and gently with water for 5-20 minutes Remove contact lenses, if present, after 5 minutes, then continue rinsing eye Call a poison control center or doctor for treatment advice Skin Contact : If on skin or clothing : Take off contaminated clothing Rinse skin immediately with plenty of water for 5-20 minutes Call a poison control center or doctor for treatment advice Inhalation : If inhaled : Move person to fresh air If person is not breathing call an ambulance, then give artificial respiration, preferably mouth-to-mouth if possible Call poison control center or doctor for further treatment advice Notes to Physician : There is no specific antidote if this product is ingested Treat symptomatically Medical Condition Likely to be Aggravated by Exposure None known 5 FIRE FIGHTING MEASURES Fire and Explosion Flash Point (Test Method) : Flammable Limits (% in Air) : Auto ignition Temperature : Flammability : Does not flash Lower : % Not Applicable Not Available Not Applicable Upper : % Not Applicable Unusual Fire, Explosion and Reactivity Hazards PRODUCT NAME : UNIK PLANT GROWTH REGULATOR Page : 2

3 OF THE EFAL CHEMICAL INDUSTRIES LTD GROUP 8, Hamlacha St, POB 823 Netanya 42293, Israel Web site: wwwefal com During a fire, irritating and possibly toxic gases may be generated by thermal decomposition or combustion In case of Fire Use dry chemical, foam or CO 2 extinguishing media Wear full protective clothing and selfcontained breathing apparatus Evacuate nonessential personnel from the area to prevent human exposure to fire, smoke, fumes or products of combustion Prevent use of contaminated buildings, area and equipment until decontaminated Water runoff can cause environmental damage If water is used to fight fire, dike and collect runoff 6 ACCIDENTAL RELEASE MEASURES In case of Spill or Leak Control the spill at its source Contain the spill to prevent it from spreading, contaminating soil, or entering sewage and drainage systems or any body of water Clean up spills immediately, observing precautions outlined in Section 8 If a solid, sweep up material and place in a compatible disposal container If a liquid, cover entire spill with absorbing material and place into compatible container Scrub area with hard water detergent Pick up wash liquid with additional absorbent and place into compatible disposal container Once all material is cleaned up and placed in a disposal container, seal container and arrange for disposition 7 HANDLING AND STORAGE Store the material in a well-ventilated, secure area out of reach of children and domestic animals Do not store food, beverages or tobacco products in the storage area Prevent eating, drinking, tobacco use, and cosmetic application in area where there is a potential for exposure to the material Wash thoroughly with soap and water after handling 8 EXPOSURE CONTROL/PERSONAL PROTECTION THE FOLLOWING RECOMMENDATIONS FOR EXPOSURE CONTROL/PERSONAL PROTECTION IS INTENDED FOR THE MANUFACTURE, FORMULATION AND PACKAGING OF THE PRODUCT FOR COMMERCIAL APPLICATIONS AND ON-FARM APPLICATIONS CONSULT THE PRODUCT LABEL Ingestion : Eye Contact : Skin Contact : Inhalation : Prevent eating, drinking, tobacco usage and cosmetic application in areas where there is a potential for exposure to the material Wash thoroughly with soap and water after handling Where eye contact is likely, use chemical splash goggles Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower Where contact is likely, wear chemical-resistant (such as nitrile or butyl) gloves, coveralls, socks and chemical-resistant footwear For overhead exposure, wear chemical-resistant headgear Respiration / Ventilation : If operating conditions result in airborne concentrations of this material, the use of an approved respirator is recommended Use adequate ventilation to keep the airborne concentration of this material below the recommended exposure standards Use process enclosures, local-exhaust ventilation, or other engineering controls to keep airborne levels below exposure limits PRODUCT NAME : UNIK PLANT GROWTH REGULATOR Page : 3

4 OF THE EFAL CHEMICAL INDUSTRIES LTD GROUP 8, Hamlacha St, POB 823 Netanya 42293, Israel Web site: wwwefal com 9 PHYSICAL AND CHEMICAL PROPERTIES Appearance : Odor Melting Point : Boiling Point Specific Gravity/Density ph Solubility in H2O Off-white/buff/beige liquid Solvent odor No data available No data available o C Not data available Forms emulsion in water Vapor Pressure No data available 0 STABILITY AND REACTIVITY Stability : Hazardous Polymerization : Conditions to Avoid : Materials to Avoid : Stable under standard conditions Will not occur None known Oxidizing agents TOXICOLOGICAL INFORMATION ACUTE (Product Specific Information) Eye Irritation: Skin Irritation: Dermal Toxicity : Oral Toxicity : Inhalation Toxicity: Slight irritation clearing in 7 days or less (Toxicity Category III) No irritation at 72 hours (Toxicity Category IV) The dermal LD 50 in rabbits is >5 g/kg (Toxicity Category IV) The oral LD 50 in rabbits is >5 g/kg (Toxicity Category IV) The 4-hour inhalation LC 50 in rats is > 59 mg/l (Toxicity Category IV) Skin Sensitization : This product did not produce a skin sensitization reaction in a modified Bueler test in guinea pigs TOXICITY OF UNICONAZOLE TECHNICAL CHRONIC/CARCINOGENICITY : A cancer bioassay in mice revealed an increased incidence of liver tumors among males exposed to 20 mg/kg/day Uniconazole via the diet There was no increase in tumors of any type in males exposed to -25 mg/kg/day or in any of the treated female groups (5-240 mg/kg/day) The biological significance of this finding is unclear because the tumors arose late in the study and fewer untreated animals were still PRODUCT NAME : UNIK PLANT GROWTH REGULATOR Page : 4

5 OF THE EFAL CHEMICAL INDUSTRIES LTD GROUP 8, Hamlacha St, POB 823 Netanya 42293, Israel Web site: wwwefal com alive at that time Uniconazole was not carcinogenic in rats exposed to mg/kg/day in the diet of a lifetime The only toxic effects observed in rats were decreased body weight gains and changes in the blood chemistry and liver cell Repeated oral or dermal exposure to Uniconazole resulted in non-specific depression of the central nervous system and changes in the liver, kidney, and blood systems in rats, mice, and dogs at dose levels greater than 5, 40, and 20 mg/kg/day for the three species, respectively The most prominent effects were produced in the liver A chronic toxicity study in dogs revealed blood chemistry changes, increased liver, kidney, and adrenal weights, and decreased thymus weights at levels of mg/kg/day The only cellular effect observed was liver cell enlargement TERATOLOGY/DEVELOPMENTAL TOXICITY: In teratology studies, minor skeletal variations were observed in the offspring of rats exposed to 25 mg/kg/day Uniconazole, while no evidence of developmental toxicity or teratogenicity was seen in rabbits REPRODUCTION: Uniconazole did not produce malformations or adverse reproductive effects in a two-generation rat reproductive study MUTAGENICITY: Genetic toxicity tests in cultured mammalian cells and in mice indicate that Uniconazole may damage genetic material, but only in dose levels that are severely toxic to the test organisms Uniconazole was not mutagenic in bacteria TOXICITY OF OTHER INGREDINTS: For a summary of the potential for adverse health effects from exposure to this product, refer to Section 3 For information regarding regulations pertaining to this product, refer t Section 5 2 ECOLOGICAL INFORMATION Summary of Effects AVIAN TOXICITY : The following tests were conducted with Uniconazole Technical: Oral LD 50 mallard duck : Oral LD 50 bobwhite quail : Dietary LC 50 mallard duck : Dietary LC 50 bobwhite quail : One generation reproduction study bobwhite quail : One generation reproduction study mallard duck : Greater than 235 mg/kg 46 mg/kg 3345 ppm Greater than 5782 ppm NOEC = 320 ppm NOEC = 80 ppm Treatment related effects observed at 320 ppm AQUATIC ORGANISM TOXICITY : The following tests were conducted with Uniconazole Technical: 96-hr LC 50 rainbow trout : 96-hr LC 50 bluegill sunfish : 96-hr LC 50 carp : 48-hr EC 50 Daphnia magna : 48 mg/l 82 mg/l 75 mg/l Greater than 0 mg/l OTHER NON-TARGET ORGANISM TOXICITY : The acute contact LD 50 of Uniconazole technical in the honey bee is greater than 20 ug/bee PRODUCT NAME : UNIK PLANT GROWTH REGULATOR Page : 5

6 OF THE EFAL CHEMICAL INDUSTRIES LTD GROUP 8, Hamlacha St, POB 823 Netanya 42293, Israel Web site: wwwefal com 3 DISPOSAL CONSIDERATION Disposal End users must dispose of any unused product as per the label recommended Do not reuse product containers Dispose of product containers, waste containers, and residues according to local state, and feral health and environmental regulations Characteristic Waste : Not Applicable Listed Waste : Not Applicable 4 TRANSPORT INFORMATION DOT Classification Non regulated Plant Growth Regulator Technical Shipping Name : Plant Growth Inhibitor, Modifier, or Regulator Uniconazole 5% solution UN Number : Not Applicable Comments : None 5 REGULATORY INFORMATION EPCRA SARA Title III Classification Section 33/32 Hazard Classes : Acute Health Hazard Chronic Health Hazard CERCLA/SARA 302 Reportable Quantity (RQ) None RCRA Hazardous Waste Classification (40 CFR 26) Not Applicable TSCA Status Exempt from TSCA subject to FIFRA 6 OTHER INFORMATION NFPA Hazard Ratings Health : Flammability : Instability : 0 HMIS Hazard Ratings Health : Flammability : Reactivity : 0 0 Minimal Slight 2 Moderate 3 Serious 4 Extreme For non-emergency questions about this product call : The information and recommendations contained herein are based upon data believed to be correct However, no guarantee or warranty of any kind, expressed or implied, is made with respect to the information contained herein PRODUCT NAME : UNIK PLANT GROWTH REGULATOR Page : 6