: GLUTAMIC ACID CRS. Safety Data Sheet Safety Data Sheet in accordance to Regulation (EC) No. 1907/2006, as amended.

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1 in accordance to Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 30/10/2007 Version: 5.0 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product form : Substance Trade name : GLUTAMIC ACID CRS EC no : CAS No : Product code : G Relevant identified uses of the substance or mixture and uses advised against Relevant identified uses Main use category Use of the substance/mixture Function or use category : The product is intended for research, analysis and scientific education. : For professional use only : Laboratory chemicals Uses advised against 1.3. Details of the supplier of the safety data sheet European Directorate for the Quality of Medicines & Healthcare EDQM, Council of Europe F Strasbourg T +33(0) F +33(0) Emergency telephone number Emergency number : +44(0) SECTION 2: Hazards identification 2.1. Classification of the substance or mixture Classification according to Regulation (EC) No. 1272/2008 [CLP] Classification according to Directive 67/548/EEC or 1999/45/EC Adverse physicochemical, human health and environmental effects 2.2. Label elements Labelling according to Regulation (EC) No. 1272/2008 [CLP] No labelling applicable 2.3. Other hazards Other hazards not contributing to the classification : Exposure may produce an allergic reaction. SECTION 3: Composition/information on ingredients 3.1. Substances Name Product identifier % Classification according to Directive 67/548/EEC GLUTAMIC ACID (Main constituent) (CAS No) (EC no) Name Product identifier % Classification according to Regulation (EC) No. 1272/2008 [CLP] GLUTAMIC ACID (Main constituent) (CAS No) (EC no) Full text of R-, H- and EUH-phrases: see section 16 12/07/2013 EN (English) 1/5

2 in accordance to Regulation (EC) No. 1907/2006, as amended Mixture SECTION 4: First aid measures 4.1. Description of first aid measures First-aid measures after inhalation First-aid measures after skin contact First-aid measures after eye contact : Move to fresh air. : Rinse with water. : Rinse eyes with water as a precaution Most important symptoms and effects, both acute and delayed Symptoms/injuries : None known Indication of any immediate medical attention and special treatment needed In all cases of doubt, or when symptoms persist, seek medical attention. SECTION 5: Firefighting measures 5.1. Extinguishing media Suitable extinguishing media 5.2. Special hazards arising from the substance or mixture Reactivity : Small amounts: Use extinguishing media appropriate for surrounding fire. Water spray. Carbon dioxide. Dry powder. Foam. Large amounts:. : Stable under normal conditions Advice for firefighters Precautionary measures fire Firefighting instructions : Small amounts: Use normal individual fire protective equipment. Large amounts:. : Dilute with water. SECTION 6: Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures General measures For non-emergency personnel For emergency responders 6.2. Environmental precautions 6.3. Methods and material for containment and cleaning up Methods for cleaning up : Avoid raising dust. Avoid all unnecessary exposure. Large amounts:. : Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Clean thoroughly. Clean with water Reference to other sections SECTION 7: Handling and storage 7.1. Precautions for safe handling Precautions for safe handling : Avoid all unnecessary exposure Conditions for safe storage, including any incompatibilities Storage conditions Incompatible products 7.3. Specific end use(s) See Heading 1. : To guarantee the quality and properties of the product, keep : dry, Keep in a cool, wellventilated place away from heat. Store in original container. : Strong oxidizing agents. SECTION 8: Exposure controls/personal protection 8.1. Control parameters 8.2. Exposure controls 12/07/2013 EN (English) 2/5

3 in accordance to Regulation (EC) No. 1907/2006, as amended. SECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties Physical state Appearance Colour Odour Odour threshold ph Relative evaporation rate (butylacetate=1) : Solid : Crystalline powder. white. colourless crystals. Powder. Melting point : C Freezing point Boiling point Flash point Self ignition temperature Decomposition temperature Flammability (solid, gas) Vapour pressure Relative vapour density at 20 C Relative density Solubility : Water: 1 mg/l Log Pow : -3,69 at 20 C Log Kow Viscosity, kinematic Viscosity, dynamic Explosive properties Oxidising properties Explosive limits 9.2. Other information SECTION 10: Stability and reactivity Reactivity Stable under normal conditions Chemical stability Possibility of hazardous reactions Small amounts: None known. Large amounts: Conditions to avoid Incompatible materials Small amounts: None under normal use. Large amounts: Hazardous decomposition products When heated to decomposition, emits dangerous fumes. Large amounts:. SECTION 11: Toxicological information Information on toxicological effects Acute toxicity GLUTAMIC ACID CRS( ) LD50 oral rat Skin corrosion/irritation Serious eye damage/irritation Respiratory or skin sensitisation Germ cell mutagenicity Carcinogenicity > mg/kg Reproductive toxicity 12/07/2013 EN (English) 3/5

4 in accordance to Regulation (EC) No. 1907/2006, as amended. Specific target organ toxicity (single exposure) Specific target organ toxicity (repeated exposure) Aspiration hazard Potential Adverse human health effects and symptoms SECTION 12: Ecological information Toxicity Ecology - general Ecology - water : To our knowledge, the product does not present any particular risk, under normal conditions of use. Large amounts:. : Small amounts: Presents no specific risk for the environment. Large amounts:. : Soluble in water Persistence and degradability Bioaccumulative potential GLUTAMIC ACID CRS( ) Log Pow -3,69 at 20 C Mobility in soil Results of PBT and vpvb assessment Other adverse effects SECTION 13: Disposal considerations Waste treatment methods SECTION 14: Transport information In accordance with ADR / RID / ADNR / IMDG / ICAO / IATA UN number No dangerous good in sense of transport regulations UN proper shipping name Transport hazard class(es) Packing group Environmental hazards Other information : No supplementary information available Special precautions for user Overland transport Transport by sea Air transport Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code SECTION 15: Regulatory information Safety, health and environmental regulations/legislation specific for the substance or mixture EU-Regulations No REACH Annex XVII restrictions 12/07/2013 EN (English) 4/5

5 in accordance to Regulation (EC) No. 1907/2006, as amended National regulations Chemical safety assessment SECTION 16: Other information SDS EU (REACH Annex II) This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product 12/07/2013 EN (English) 5/5

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