Mr Maarten van der Heijden

Transcription

1 Mr Maarten van der Heijden Manager Health and Preservation, Nutreco Strategies of salmonella controls via drinking water & feed Sponsored by: Nutreco

2 Strategies for Salmonella control via drinking water and feed Maarten van der Heijden Business Development Manager Selko Feed Additives

3 Content Salmonella an important Zoonosis Infection routing of Salmonella at animal level 2 Salmonella Intervention study s: Feed and water acidification at fattening pigs Multiple barrier approach in feed for broiler chickens Conclusion

4 Selko Feed Additives, A Business Unit of Nutreco Animal Nutrition Global leader in antimicrobial, health supporting and nutritional feed additive products for resolving current and future feed safety and animal performance challenges. Expertise over more than 29 years Part of Nutreco, a world leader in animal nutrition Access to world class research and development facilities of Nutreco

5 Food Safety control Important themes at Selko Feed Additives Food Safety Animal Welfare Salmonella reduction while saving costs Footpad lesions reduction while maintaining high stocking density

6 Salmonella important Zoonosis Salmonella reported by EFSA (European Food Safety Agency) EU-2010 Human Salmonella prevalence confirmed cases of human salmonellosis S. Enteritidis 45% and S. Typhimurium 22,4% Salmonella presence in Food fresh broiler meat: 4.8 % fresh turkey meat: 9.0 %, fresh pig meat: 0.9 %

7 Former EU commissioner for health and consumer protection Salmonella Control started at Farm level Reducing the incidence of Salmonella at farm level will lower its incidence through the rest of the food chain, and help meet the ultimate objective of protecting EU consumers," 7 Picture: Centre of disease control, Atlanta

8 To secure Food Safety we need to protect our farm animals!

9 The beak most important port-entree Feed & water treatment easy route for Salmonella control???????

10 Salmonella infection routing in farm animals Feed Water Animal Environment Oral uptake Survival Crop/Stomach Attachment mucosa Intestinal Multiplication Systemic infection Invasion enterocytes Excretion via faeces Gall-bladder Liver Spleen Lungs

11 2 intervention study's via Water & Feed Fattening pigs and broilers by Feed Additives Pigs: Broilers: Fysal Fit-4

12 Intervention study 1: Fattening pigs Materials & method: Farm selection Farms: 36 Commercial swine herds Different sizes: from fatteners Compound feed: 1 feed mill Phase 1: Year 1 Selection of Salmonella status Blood sampling at slaughter, every 3 months, 15 blood samples (60 total) IDEXX-ELISA test on Salmonella antibodies : Dutch Animal Health Service Phase 2: Assignment of farms to Low or High Salmonella antibody titers High: Average titer O.D. > farms = 69% Treatment group Low/Negative: Average titer O.D. < farms = 31%

13 Application organic acids via feed or water 36 Commercial fattening farms the Netherlands: delivered pigs 13 High Salmonella Treatment group Hygiene & Management group: HACCP based farm specific measures; Farm specific advice 5 herds; delivered pigs Feed treatment: Acidifying feed; 0,85 % RAMF; Mixture of Formic acid + Ammonium formate: dosed by feed company 10 herds; delivered pigs Water treatment: Acidifying drinking water: 0,2 % Selko-pH: Mixture of Formic acid + Ammonium formate; Acetic acid etc. ph water is stabilized between herds; delivered pigs Low Salmonella Negative group: No additional measures 11 herds; delivered pigs

14 Salmonella titer effect of the different treatments The effect of different treatments on the Salmonella titer (mean O.D%), measured over time, per group. Treatment was iniated after sampling period 4.

15 Significant reduction Salmonella titer & economical net benefit by water acidification Farms Before treatment After treatment % Titer < O.D 20 Average titer % Titer < O.D 20 Average titer Statistical Significance (P < 0,05) Negative 100% % 17 No Hygiene procedure 75% % 14 No Acidification feed 50% % 16 Yes Acidification water 50% % 9 Yes Δ Daily gain Δ FCR Net benefit Negative -5 +0,12 0 Hygiene procedure -7 +0,10 +0,30 Acidification feed -55* +0,04-2,10 Acidification water +26-0,08 +2,53 15 Statistic analysis done by Quantitative Veterinary Epidemiology group University Wageningen, This field trail is partly financed by the Dutch Product board of Meat and Eggs, The Netherlands.

16 Intervention study 2: Broiler via Feed Multiple barrier feed additive: Fysal Fit-4

17 Salmonella challenge model broilers Nutreco R&D Materials & Method: 300 male Ross broilers 6 floor pens, each 50 broilers 2 replicates per treatment started from day 1 Oral challenge with 10 x6 Salmonella Enteriditis day 7&8 Sampling / analysis: 10 birds were randomly selected from each pen at day 22, 31 and 43 Determination of individual Salmonella counts in the ceca. (log cfu/g) Determination of Bifidobacterium

18 Multiple barrier Feed additive Organic acids; Mannobiose; MCFA, Butyrates Multiple barriers product to control Salmonella 1. Reduce feed contamination by Organic acids combination 2. Prevent Salmonella colonization, by a non fermentable plant-extract containing the bisugar Mannobiose (fimbrae-1 blocker) 3. Prevent intestinal multiplication and excretion by MCFA 4. Prevent invasion by a slow release Butyrate source Treatments Dose 0-21 day Dose day 1 Negative control 2 Fysal Fit-4: Flat Fysal Fit-4: High / Low

19 Multible barriere product effective in prevention Salmonella colonization and excreation 96% reduction of Salmonella at ceca level High / low (0,3-0,1%) application scheme is most effective: -/- 1,4 log/gr reduction Multiple barrier product stimulate Bifidobacterium: +/+ 1,3 log/gr

20 Multiple barrier approach effective in combination with a total Salmonella control program Integrator of mln broiler integrator free In 1 year time reduction from 15 to 1 % positive carcasses for S.e. / S.t

21 Summary Application of feed additives via feed or drinking water showed to be very effective in Salmonella control under trail circumstances but also under field conditions. Thanks for your attention!