Critical Care Standard Infusion Concentrations
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- Abner Dalton
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1 Acetylcisteine (NAC) Actrapid - Human Insulin Addiphos 20mmol Addiphos 40mmol Adrenaline (Epinephrine) vs peripheral 10 g in 50mL 200mg per ml 50 units in 50mL 1 unit per ml sodium chloride 20 mmol in 25mL 0.8mmol per ml glucose 5% 40 mmol in 50mL 0.8mmol per ml glucose 5% 3 mg in 50 ml 6 mg in 50 ml 60 micrograms per ml 120 micrograms per ml Alfentanil 20 mg in 40 ml 500 micrograms per ml Alfentanil (HIGH STRENGTH) 100 mg in 50 ml 2mg per ml Alteplase 50 mg in 50mL 1mg per ml Aminophylline mg in 250 ml 1 mg per ml Aminophylline mg in 50 ml 5 mg per ml Amiodarone Critical Care Standard Infusion Concentrations The maximum expiry for any injection / infusion prepared in a clinical area is 24 hours or less, in accordance with the manufacturer s summary of product characteristics. The information within this table is not for reproduction or circulation. Some medications / methods of administration may be unlicensed. This table should be used in conjunction with the Trust IV guide (Medusa), however some information may differ as this is local critical care practice. Please note many of the concentrations listed are suitable for central administration only. 300mg in 50mL (load) 300mg in 48mL (infusion) 600mg in 48mL 900mg in 48mL 300 mg / 50mL 6 mg / ml 300 mg / 48mL 6.25 mg / ml 600 mg 12.5 mg / ml 900 mg mg / ml Glucose 5% (Use pre-diluted 0.5 mg /ml) Pre-filled syringe prepared by Pharmacy Glucose 5% only DTC Reference: 15095a By: August 2018
2 Amiodarone - Aprotinin 300 mg in 250mL (load) 300 mg in 500mL (infusion) 600 mg in 500mL 900 mg in 500mL 500,000 units in 50mL Argatroban 250 mg in 250mL 1 mg per ml Atracurium 250 mg in 25mL 300 mg 250mL = 1.2 mg/ml 300 mg 500mL = 0.6mg/mL 600 mg 500mL = 1.2mg/mL 900 mg 500mL = 1.8mg/mL Calcium Chloride 20mmol 20 mmol in 40mL 0.5mmol per ml Cisatracurium Clonidine Co-trimoxazole 150 mg in 30mL 1500 micrograms in 50mL 30 micrograms per ml 2400 mg in 25mL Dexmedetomidine 1000 micrograms in 50mL 20 micrograms per ml Glucose 5% only vs peripheral 10,000 units per ml 10 mg per ml 5 mg per ml 96 mg per ml Diamorphine 100 mg in 50mL 2 mg per ml Glucose 5% Dobutamine 250 mg in 50 ml 5 mg per ml Glucose 5% Dopamine 200 mg in 50 ml 4 mg per ml Glucose 5% Dopexamine 50 mg in 50 ml 1 mg per ml Glucose 5% DTC Reference: 15095a By: August 2018
3 Doxapram Epoprostenol CVVH Epoprostenol - Systemic 500 micrograms in 50 ml 1000 mg in 500mL 2 mg per ml Glucose 5% 500 micrograms in 50 ml 10 micrograms per ml 10 micrograms per ml Diluent provided or sodium chloride Diluent provided or sodium chloride Esmolol 2500 mg in 250mL 10 mg per ml glucose 5% vs peripheral or via haemofilter Fentanyl 2.5 mg in 50 ml 50 micrograms per ml Fomepizole continuous infusion for CRRT 1500 mg in 250mL (N.b. concentration may vary depending on product available check with Pharmacy) 6 mg per ml Furosemide 250 mg in 50ml 5 mg per ml Glyceryl trinitrate 50 mg in 50 ml 1 mg per ml Glucose 5% Heparin (Systemic anticoagulation) 20,000 units in 20 ml 1,000 units per ml Heparin CVVH/HDF (Haemofiltration) 10,000 units in 40 ml 250 units per ml Via haemofilter Hydralazine 20 mg in 50 ml 400 mcg per ml Hydrocortisone 100 mg in 50ml 2 mg per ml Sodium Chloride Iloprost 100 micrograms in 50mL 2 micrograms per ml sodium chloride Isoprenaline 4 mg in 50 ml 80 micrograms per ml Glucose 5% DTC Reference: 15095a By: August 2018
4 Labetalol 200 mg in 40 ml 5 mg per ml Levosimendan Lignocaine 0.2% (Lidocaine) Liothyronine infusion vs peripheral via central line (Refer to Medusa for dilution instructions for peripheral use) 12.5 mg in 250mL 50 micrograms per ml Glucose 5% 1000 mg in 500mL 2 mg per ml Glucose 5% 20 micrograms in 20mL 1 micrograms per ml Water for injection Lorazepam 10 mg in 50 ml 200 micrograms per ml Glucose 5% only Magnesium 20 mmol in 50mL 0.4 mmol per ml Metoprolol 20 mg in 50mL 0.4 mg per ml Midazolam 100 mg in 50 ml 2 mg per ml Milrinone (at these concentrations) 10 mg in 50 ml 200 micrograms per ml Glucose 5% Morphine 50 mg in 50 ml 1 mg per ml Naloxone 2000 micrograms in 500mL 4 micrograms per ml Glucose 5% N-Acetylcysteine 10 g in 50 ml 200 mg per ml Nimodipine 10 mg in 50 ml 200 micrograms per ml (see adjacent column) - via dedicated line, co-infused with 40mL per hour sodium chloride DTC Reference: 15095a By: August 2018
5 Noradrenaline (Norepinephrine) Octreotide Pantoprazole Phosphate polyfusor Potassium chloride Propofol 4 mg in 50 ml 8 mg in 50 ml 16 mg in 50 ml 80 micrograms per ml 160 micrograms per ml 320 micrograms per ml 1000 micrograms in 50mL 20 micrograms per ml 40 mg in 50 ml 0.8 mg per ml 50 mmol in 500mL 20 mmol in 50 ml (Where available, use 20mmol in 100mL prepared bags.) 1% mg in 50 ml 2% mg in 50 ml Glucose 5% vs peripheral 0.1 mmol per ml neat 0.4 mmol per ml 10 mg per ml 20 mg per ml Remifentanil 5 mg in 50 ml 100 micrograms per ml DTC Reference: 15095a By: August 2018 Rocuronium 300 mg in 30 ml 10 mg per ml Salbutamol Salbutamol Sodium Nitroprusside Thiopentone Tranexamic acid 5 mg in 500 ml 10 micrograms per ml Glucose 5% 5 mg in 50 ml 100 micrograms per ml Glucose 5% 50 mg in 50 ml 1000 mg in 40mL 5000 mg in 50mL Vancomycin 500 mg in 50 ml 10 mg per ml Vasopressin (Argipressin) 1 mg per ml Glucose 5% only 25 mg per ml Water for injection 100 mg per ml 20 units in 40mL 0.5 units per ml Glucose 5%
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