UNIVERSITY OF CAMBRIDGE INTERNATIONAL EXAMINATIONS General Certificate of Education Advanced Subsidiary Level and Advanced Level

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1 UNIVERSITY F AMBRIDGE INTERNATINAL EXAMINATINS General ertificate of Education Advanced Subsidiary Level and Advanced Level * * BILGY 9700/02 Paper 2 Structured Questions AS May/June hour 15 minutes andidates answer on the Question Paper. No Additional Materials are required. READ TESE INSTRUTINS FIRST Write your entre number, candidate number and name on all the work you hand in. Write in dark blue or black pen. You may use a soft pencil for any diagrams, graphs or rough working. Do not use staples, paper clips, highlighters, glue or correction fluid. D NT WRITE IN ANY BARDES. Answer all questions. At the end of the examination, fasten all your work together. The number of marks is given in brackets [ ] at the end of each question or part question Total This document consists of 15 printed pages and 1 blank page. SPA (FF/DT) T60104/3 ULES 2008 [Turn over

2 2 Answer all the questions. 1 Fig. 1.1 shows the heart and associated blood vessels. right atrium Fig. 1.1 (a) n Fig. 1.1, draw label lines and use the letters P, Q and R to indicate the following structures: P Q a blood vessel that carries deoxygenated blood a structure that prevents backflow into a ventricle R a blood vessel that carries blood at high pressure [3] (b) The changes in blood pressure in the right atrium are the same as those in the left atrium. The changes in blood pressure in the right ventricle are different from those in the left ventricle. Explain why this is so.... [4] ULES 2008

3 3 (c) Some components of tobacco smoke are absorbed into the blood stream and affect the cardiovascular system. Describe the effects of nicotine and carbon monoxide on the cardiovascular system. nicotine... carbon monoxide [4] [Total: 11] ULES 2008 [Turn over

4 4 2 Fig. 2.1 is an electron micrograph of part of an animal cell. A centriole is labelled. A B centriole X 10, 000 Fig. 2.1 ULES 2008

5 5 (a) Name the structures labelled A to. A... B [3] (b) Describe the roles of centrioles in animal cells.... [3] (c) Explain why it is possible to see the internal membranes of a cell in electron micrographs, such as Fig. 2.1, but it is not possible to see them when using the light microscope.... [3] ULES 2008 [Turn over

6 6 (d) A student investigated the effect of temperature on beetroot tissue. Beetroot cells contain a dark red pigment known as betalain, which is stored inside their vacuoles. The student cut the beetroot tissue into cubes of the same size washed the cubes thoroughly in distilled water placed the same number of cubes into distilled water at seven different temperatures. After 30 minutes, samples of the water were removed and placed in a colorimeter to measure the transmission of light. The lower the percentage transmission the more betalain is present in the water. The results are shown in Fig percentage transmission temperature / Fig. 2.2 ULES 2008

7 7 Using the information in Fig. 2.2, (i) describe the student's results;... [3] (ii) explain the effect of increasing temperature on the beetroot tissue.... [3] [Total: 15] ULES 2008 [Turn over

8 8 3 Fig. 3.1 shows seven biological molecules, labelled D to K. D 2 G N P N - E S N 2 N 2 N 3 N + 3 J 2 N 3 F P - K Fig. 3.1 ULES 2008

9 9 (a) Table 3.1 contains statements about the biological molecules in Fig omplete the table by selecting the biological molecule from Fig. 3.1 that matches each of the statements. Write the appropriate letter from Fig. 3.1 in the table. The first one has been done for you. You may use each letter once, more than once or not at all. Table 3.1 statement an amino acid that is a major constituent of collagen letter J a component of RNA a molecule that is polymerised to form glycogen a molecule with a peptide bond an important store of energy, insoluble in water a molecule with hydrophilic and hydrophobic regions an amino acid that forms disulfide (disulphide) bonds in proteins [6] (b) Describe two ways in which the structure of DNA differs from the structure of collagen [2] [Total: 8] ULES 2008 [Turn over

10 10 4 Scientists at the Tibet Institute of Medical Sciences in Lhasa investigated differences between adult Tibetans who had lived in Lhasa (altitude 3658 m) all their lives and adult an hinese residents who had lived there for about 8 years. The Tibetans and the an hinese exercised at maximum effort and various aspects of their breathing were measured. Some of the results are shown in Table 4.1. Table 4.1 feature Tibetans an hinese minute volume / dm 3 min oxygen uptake / cm 3 kg 1 min Minute volume. This is the volume of air breathed in during one minute. xygen uptake. This is the volume of oxygen absorbed into the blood during one minute. It is expressed per kg of body mass. The researchers observed that the greater minute volume of the native Tibetans resulted from a greater tidal volume the tidal volumes of the Tibetans showed a positive correlation with their vital capacity measurements the an hinese had lower values for both tidal volume and vital capacity. (a) State what is meant by the term tidal volume.... [1] (b) Suggest why the researchers also measured the vital capacity of the people in the study.... [2] (c) Explain how the minute volume at rest would be determined.... [2] ULES 2008

11 11 (d) Suggest two differences in the structure of the lungs that may account for the greater oxygen uptake by the Tibetans shown in Table [2] (e) When people who have lived all their lives at low altitude go to a place at high altitude, such as Lhasa, they are often breathless, lack energy and suffer from altitude sickness. owever, with time, they often acclimatise to the high altitude. In another study, researchers found that the red blood cell count increases in such people by about 30% over several weeks. Explain why the red blood cell count increases so much when people visit places at high altitude.... [2] [Total: 9] ULES 2008 [Turn over

12 12 5 An estimated 300 to 500 million cases of malaria occur worldwide each year resulting in 1 to 3 million deaths. 80% of these cases are in children under the age of five. There are four species of malarial parasite, of which Plasmodium falciparum is responsible for most of the deaths from this disease. (a) Describe how the malarial parasite is transmitted.... [3] (b) Several potential vaccines against malaria have been developed. Some of these make use of proteins from the surface membrane of P. falciparum. (i) Explain how using such a vaccine may give long-term immunity to malaria.... [4] (ii) Researchers have been trying to develop a successful vaccine against malaria for about 20 years. Explain why it has proved so difficult to develop such a vaccine.... [2] ULES 2008

13 13 (c) Proteins on the surface of the parasite are responsible for binding to surface receptors on the red blood cells. These are removed when the parasites enter the red blood cells. An enzyme has recently been discovered in P. falciparum that is responsible for the removal of these proteins. If the enzyme does not function then the parasites cannot enter red blood cells. It has been suggested that a drug could be developed to inhibit this enzyme. Describe one possible way in which such a drug might act on the enzyme to prevent it from functioning.... [3] [Total: 12] ULES 2008 [Turn over

14 14 6 Fig. 6.1 shows some feeding relationships in an Arctic ecosystem. polar bear glaucous gull ringed seal Arctic fox little auk Arctic cod amphipods shrimps squid eider duck bearded seal herbivorous copepods mussels and snails bottom-dwelling crustaceans phytoplankton decomposing organic matter Fig. 6.1 (a) Using the information shown in Fig. 6.1, (i) name two organisms that are feeding as secondary consumers;... [1] (ii) explain why it is difficult to assign some organisms to trophic levels.... [2] ULES 2008

15 15 (b) The efficiency of energy transfer through a trophic level is calculated by comparing the energy available to that trophic level with the energy available to the next trophic level. It has been estimated that the efficiency of energy transfer by herbivorous copepods is about 17%. State two factors that are likely to influence the efficiency of energy transfer by herbivorous copepods [2] [Total: 5] ULES 2008

16 16 BLANK PAGE opyright Acknowledgements: Question 2 Fig. 2.1 Dr. Don W. Fawcett / Visuals Unlimited. Permission to reproduce items where third-party owned material protected by copyright is included has been sought and cleared where possible. Every reasonable effort has been made by the publisher (ULES) to trace copyright holders, but if any items requiring clearance have unwittingly been included, the publisher will be pleased to make amends at the earliest possible opportunity. University of ambridge International Examinations is part of the ambridge Assessment Group. ambridge Assessment is the brand name of University of ambridge Local Examinations Syndicate (ULES), which is itself a department of the University of ambridge.

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