Company & Brand Identity. Educational manual January 2016 Medisoul

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1 Company & Brand Identity Educational manual January 2016 Medisoul

2 JointPro A new natural approach for joint pain and derived Inflammation conditions. Natural Health Product Registration A topical cream for immediate ease of pain due to inflammation and reduction of inflammation caused by sprain/strain or Rheumatoid Arthritis. How to Use: Topical, on unbroken skin, massage into area afflicted with pain and/or inflammation. Use as directed to relieve pain and ease inflammation for no longer than 7 consecutive days or see a physician in the event of other underlying cause. When Can Results Be Seen? Relief of pain will be experienced immediately upon topical application.

3 Major Active Ingredients There are 5 essential and major active ingredients all with proven accolades and merit. According to the NNHPD essential oil product monograph Rosemary, Thyme and Clove essential oils in combination are used to relieve joint/muscle pain associated with sprain/strain/ra. Anti-inflammatory, anti-oxidant, and provides relief for muscle aches and pains Thyme - the health benefits of thyme essential oil can be attributed to its properties as an antispasmodic, anti-rheumatic, antiseptic, bactericidal Clove - Natural anti-inflammatory

4 The two other essential ingredients which substantiate the outstanding efficacy and strength of Joint Pro is Resveratrol and Pterostilbene Resveratrol Resveratrol is a powerful antioxidant that is produced by some plants to protect against environmental stresses. It is more commonly known, however, as the active ingredient in red wine that protects against heart disease. One of the major functions discovered about Resveratrol is its anti-inflammatory attributes Pterostilbene One of the most powerful antioxidant and anti-inflammatory ingredients sourced from Blueberries.

5 The major 5 active ingredients in JointPro are formulated in conjunction with the other natural ingredients in a correct effective combination. Three are essential oils that are scientifically and clinically recognized to reduce pain due to inflammation. The synergy between Resveratrol and Pterstilbene boost the benefits of JointPro to unprecedented levels compared to analgesic rubs natural or otherwise. The combination of Rosemary, Thyme, Clove essential oils with the Resveratrol and Pterstilbene and their own merits work to relieve pain immediately and affect dramatically associated inflammation. Bioactive Stabilized Activated Catechins Stable Phyto Isothicyanates Molecules JointPro Boswelia Therapeutic Essential Oil Absorbable Curcumin C Complex Novel Resveratrol Polyphenols Catechins Natural Phenol and Anti-Oxidant. Plant extract Phyto Isothicyanates Sulphur extracted from plants. One of the strongest anticancer effects Therapeutic Dosage

6 Studies We demonstrate a new patent pending method to treat and stabilize the ECM in an effort to reduce, eliminate, or prevent harmful cellular processes including aberrant tras angiogenesis, inflammation, microcalcification, and the development of neoplastic disease. Patent pending JointPro MDMatrix Therapeutic Cream demonstrates a strong ability to combat these and other disease states by improving mammalian cellular function, promoting healthy tissue development, reducing inflammation and stabilizing one or more components of mammalian ECM. Extended studies were conducted to validate the effectiveness of JointPro including an assessment of its anti-inflammatory activity in a prophylactic and therapeutic model of ear edema (as one of the examples). JointPro was able to achieve a statistically significant 57% inhibition of the oxazolone-induced ear edema compared to just 37% inhibition with oral celecoxib. JointPro at 57% inhibition was able to achieve comparable results with topical betamethasone (69% inhibition) while only utilizing active ingredients from natural plant extracts.

7 JointPro V Major Competitors JointPro s scientifically and clinically approved formula leading benefits: Immediate reduction of pain due to inflammation Inflammation reduction caused by sprain/strain or Rheumatoid Arthritis No numbing Deep penetration Fast absorption

8 Competitors Voltaren Emulgel Major active ingredients: Camphor and Menthol Cooling and heating properties Contains Diclofenac. has been associated with significantly increased vascular and coronary risk. Non-steroid, reduce inflammation Contains analgesic reducing agent NOT NATURAL Bengay Major active ingredients: Camphor, Menthol and Methylsalycilate. Ingredients are largely numbing, can cause burn, no indication as anti-inflammatory NOT NATURAL Lakota joint pro Major ingredients: Glucosamine, White willow bark - work as aspirin Under NPN- no immediate claims for fast pain relief NATURAL Natural Emu Oil Major ingredient: Emu oil (can be effective only in its natural form) In use for treating inflammation only No clinical studies to support claims ANIMAL SOURCE

9 JointPro - Additional Organic Active Ingredients Sweet Orange Oil Broccoli Seed Mustard Seed Oil

10 Acetone Topical Betame- Thaosne (Steroid) Topical JointPro Oral Celecoxib In another study utilizing thermography, JointPro was able to decrease inflammation in numerous tissues and alleviate pain and swelling. Participants noted a decrease in joint pain and inflammation not only in the tissue to which it was applied, but also a decrease in the hands the cream was applied with.

11 A number of ADDITIONAL studies and patient data was gathered regarding the effectiveness of JointPro for the management of a number of other inflammatory based conditions including, sunburn, elevated prostate-specific antigen (PSA), eczema, TMJ, insect bite pain and swelling and many more. JointPro was able to improve these issues significantly and greatly increase patient relief. This study data demonstrates the potent and synergistic actions of the actives contained in JointPro. Moreover, the in vivo studies also demonstrated that JointPro was useful in both prophylaxis as well as in therapy of inflammation, and for stabilization of the mammalian ECM. This could be of particular interest to the 19% of Americans who deal with chronic pain and joint inflammation on a daily basis. Demonstrating an effective way to combat this malady may prove to serve a large portion of our aging population. Before Before After After

12 Symptoms Solution Results

13 INCI Medica Head office: 23 Lesmill Road, Unit 205 Toronto ON, M3B 3P6, Canada

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