NOVEMBER 06 th, h00-18h00 - Samuel Pessoa Conference. Laureado: Alvaro José Romanha (CPqRR Fiocruz, Belo Horizonte, MG, Brasil)

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1 NOVEMBER 6 th, 2017 NOVEMBER 06 th, h00-20h00 Registration Welcome & Announcements 16h30-17h00 - Meeting Opening 17h00-18h00 - Samuel Pessoa Conference Edmundo Grisard Laureado: Alvaro José Romanha (CPqRR Fiocruz, Belo Horizonte, MG, Brasil) The Personal and Scientific Lifeline of Álvaro José Romanha, a Science Craftsman Mário Steindel (UFSC, Florianópolis, SC, Brasil) 20h00-20h30 - Reunião do Conselho/ Board Meeting aependi 20h30-22h30 Poster Session ODD Numbers/Números ÍMPARES 1

2 NOVEMBER 7 th, h00 11h00 - OP.01 - Oral Presentations BIOLOGY OF HOST-PARASITE INTERACTION 09h00-11h00 - OP.02 - Oral Presentations BIOLOGY OF PROTOZOA AND THEIR VECTORS 09h00-11h00 - OP.03 - Oral Presentations TRANSLATIONAL BIOLOGY Room C Aiuruoca 11h00-11h30 - COFFEE BREAK 11h30-12h00 Flash Presentantion 12h00-12h30 - CO.01 - Conference Evolution of the nucleus: Lamina and the nuclear pore complex in trypanosomes Mark Field (University of Dundee, Dundee, UK) 12h30-14h00 - LUNCH 14h00-16h00 - RT.01 - RoundTable METABOLOMICS/PROTEOMICS OF PARASITIC PROTOZOA Purine and pyrimidine transporters of kinetoplastid parasites Harry de Koning (University of Glasgow Glasgow, UK) Quantitative proteomics unravels Trypanosoma cruzi chromatin and histone post translational modifications Julia Pinheiro Chagas da Cunha (Butantan, São Paulo, SP, Brasil) Metabolic adaptation towards metacyclogenesis in Trypanosoma cruzi: a targeted metabolomics approach María Julia Barisón (Carlos Chagas Institute Fiocruz Paraná - Curitiba, PR, Brasil) Changes in the proteome of Leishmania-infected macrophages Richard Burchmore (University of Glasgow Glasgow, UK) 14h00-16h00 - RT.02 - RoundTable APICOMPLEXA / TOXOPLASMA GONDII Unraveling the composition and function of the Toxoplasma gondii inner membrane complex Peter John Bradley (UCLA, Los Angeles, USA) Histone variants and epigenetic modulation of chromatin in Toxoplasma gondii Sergio Angel (Univ. Nac. de San Martin, Buenos Aires, Argentina) 2

3 NOVEMBER 7 th, 2017 New molecular tools to study Neospora caninum and other apicomplexan parasites Tiago Wilson Patriarca Mineo (UFU, Uberlândia, MG) Using comparative approaches to understand life cycle evolution in Toxoplasma gondii Jon Boyle (University of Pittsburgh, Pittsburgh, PA, USA) 16h00-16h30 - COFFEE BREAK 16h30-17h00 - MC.01 - Mini Conference Redox Paradox: The contribution of Reactive Oxygen Species (ROS) in the proliferation and differentiation of Trypanosoma cruzi Marcia Cristina Paes (UERJ, Rio de Janeiro, RJ, Brasil) 16h30-17h00 - MC.02 - Mini Conference Extracellular vesicles in pathogenic protozoans: role during the host-parasite interface Rodrigo Pedro Pinto Soares (FIOCRUZ, Belo Horizonte, MG, Brasil) 17h00-17h30 - MC.03 - Mini Conference Blastocrithidia, a trypanosomatid with all three stop codons reassigned Julius Lukes (Czech Academy of Sciences, Prague, Czech Republic) 17h00-17h30 - MC.04 - Mini Conference Leishmania development in sand flies: insight into specific and non-specific interactions Petr Volf (Charles University, Prague, Czech Republic ) 18h30-19h30 - Plenary Session of SBPz EVEN Numbers/Números PARES 20h30-22h30 - Poster Session 3

4 NOVEMBER 8 th, h00-11h00 - OP.04 - Oral Presentations BIOLOGY OF HOST-PARASITE INTERACTION 09h00-11h00 - OP.05 - Oral Presentations BIOLOGY OF PROTOZOA AND THEIR VECTORS 09h00-11h00 - OP.06 - Oral Presentations TRANSLATIONAL BIOLOGY Room C Aiuruoca 11h00-11h30 - COFFEE BREAK 11h30-12h00 - CO.02 - Conference Identifying and Validating New Targets for Neglected Tropical Diseases Patrick Steel (University of Durham, Durham, UK) 12h00-12h30 - MC.05 - Mini Conference Unexpected phenotypic variability of Trypanosoma brucei parasites Luísa Figueiredo (University of Lisboa, Lisboa, Portugal) 12h00-12h30 - MC.06 - Mini Conference Molecular pathogenesis of Chagas disease cardiomyopathy Edecio Cunha-Neto (USP, São Paulo, SP, Brasil) 12h30-14h00 - LUNCH 14h00-16h00 - RT.03 Round Table GENOME A CRISPR-Cas9 toolkit for loss-of-function screens in Leishmania Eva Glunz (University of Oxford, Oxford, UK) Development of Attenuated Vaccine Strains of Leishmania Genome Editing Greg Matlashewski (McGill University, Montreal, Canada) using CRISPR-Cas 4

5 NOVEMBER 8 th, 2017 Extending the Trypanosoma cruzi experimental tool box by combining bioluminescence, fluorescence and high-throughput genome editing technology John Kelly (London School of Hygiene and Tropical Medicine, London, UK) Two essential thioredoxins mediate protein import and gene expression of the Toxoplasma gondii plastid Lilach Sheiner (University of Glaskow, Glaskow, UK) 14h00-16h00 - RT.04 Round Table IMMUNOLOGY INTERLEUKIN 32: A NEW PLAYER IN LEISHMANIASIS Fátima Ribeiro Dias (UFGO, Goiânia, GO, Brasil) T Follicular helper cells regulate the activation of B lymphocytes and antibody production during Plasmodium vivax infection Lis Ribeiro do Valle Antonelli (CpRR Fiocruz, Belo Horizonte, MG, Brasil) Role of Purinergic Receptors in Controlling of T. gondii Infection Robson Coutinho e Silva (UFRJ, Rio de Janeiro, RJ, Brasil) Using Trypanosoma cruzi-derived components as strategies to modulate the host s immune response: towards the prevention of Chagas disease ardiomyopathy Walderez Ornelas Dutra (UFMG, Belo Horizonte, MG, Brasil) 16h00-16h30 - COFFEE BREAK 16h30-17h00 - MC.07 - Mini Conference Density-dependent development and social interaction between African trypanosome species in the mammalian bloodstream Keith Mathews (University Edinburgh, Edinburgh, UK) 16h30-17h00 - MC.08 - Mini Conference Development of potential diagnostic tests for the control of visceral leishmaniasis Ricardo Toshio Fujiwara (UFMG, Belo Horizonte, MG, Brasil) 17h00-18h00 - CC Closure Conference RNA-binding proteins and RNA granules: A complex response to a single stress signaling for T.cruzi differentiation Samuel Goldenberg (ICC/Fiocruz, Curitiba, PR, Brasil) 5

6 NOVEMBER 8 th, h00-19h00 - Brainstorm 19h00-21h00 Signature of Receipts to SBPz Members 21h30-22h30 CLOSING SESSION Zigman Brener and Walter Colli Awards and Closing Remarks 6