0091 Organix Comprehensive Profile - Urine

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1 3425 Corporate Way Duluth GA USA Fax: Ordering Physician: Accession #: Reference #: Patient: Date of Birth: Age: Sex: Reprinted: 07/04/ Female 05/23/2013 Date Collected: Date Received: 04/03/ /04/2012 Telephone: (770) Fax: (770) Main St. Anywhere, GA Organix Interpretation Organix Interpretive Guide is downloadable at: Florida Clinical Lab Lic. #

2 3425 Corporate Way Duluth GA USA Fax: Ordering Physician: Accession #: Reference #: Patient: Date of Birth: Age: Sex: Reprinted: 07/04/ Female 05/23/2013 Date Collected: Date Received: 04/03/ /04/2012 Telephone: (770) Fax: (770) Main St. Anywhere, GA Summary of Abnormal Findings Fatty Acid Metabolism Carbohydrate Metabolism Energy Production Markers Citrate Cis-Aconitate Isocitrate Findings Intervention Options Arginine Arginine Arginine Common Metabolic Association Renal ammonia loading Renal ammonia loading Renal ammonia loading B-Complex Vitamin Markers Methylation Cofactor Markers Neurotransmitter Metabolism Markers Homovanillate 5-Hydroxyindoleacetate Picolinate Low Very Low Very Low Tyrosine 5-HTP Limit omega-3 PUFA, add protein Dopamine turnover inhibition Serotonin turnover inhibition Suppressed inflammatory responses Oxidative Damage and Antioxidant Markers p-hydroxyphenyllactate Vitamin C, Vitamin E Increased cell turn over Detoxification Indicators Glucarate a-hydroxybutyrate Pyroglutamate Sulfate Low N-acetylcysteine, Hepatic support N-acetylcysteine, other sulfur containing amino acids N-acetylcysteine, other sulfur containing amino acids N-acetylcysteine, Lipoic acid Hepatic Phase I and II detox Glutathione demand Glutathione wasting Chronic low total body glutathione status, detox and antioxidant status Florida Clinical Lab Lic. #

3 3425 Corporate Way Duluth GA USA Fax: Ordering Physician: Accession #: Reference #: Patient: Date of Birth: Age: Sex: Reprinted: 07/04/ Female 05/23/2013 Date Collected: Date Received: 04/03/ /04/2012 Telephone: (770) Fax: (770) Main St. Anywhere, GA Bacterial - General L. acidophilus / general bacteria Clostridial Species Yeast/Fungal Florida Clinical Lab Lic. #

4 3425 Corporate Way Duluth GA USA Fax: Ordering Physician: Accession #: Reference #: Patient: Date of Birth: Age: Sex: Reprinted: 07/04/ Female 05/23/2013 Date Collected: Date Received: 04/03/ /04/2012 Telephone: (770) Fax: (770) Main St. Anywhere, GA This report is not intended for the diagnosis of neonatal inborn errors of metabolism. Results Ranges are for ages 1-12 mcg/mg creatinine Nutrient Markers 95% Reference Range Fatty Acid Metabolism (Carnitine & B2) 1. Adipate <= Suberate 0.7 <= Ethylmalonate 0.9 <= 9.4 Carbohydrate Metabolism (B1, B3, Cr, Lipoic Acid, CoQ10) Pyruvate 2.4 <= L-Lactate ß-Hydroxybutyrate <DL* <= 7.9 Energy Production (Citric Acid Cycle) (B comp., CoQ10, Amino acids, Mg) Citrate 814 H Cis-Aconitate 85 H Isocitrate 214 H a-ketoglutarate 16.0 <= Succinate 17.3 <= Fumarate 0.68 <= Malate 0.8 <= Hydroxymethylglutarate 1.8 <= 13.9 Florida Clinical Lab Lic. # Page 1

5 Ordering Physician: Reprinted: 05/23/2013 This report is not intended for the diagnosis of neonatal inborn errors of metabolism. Results Ranges are for ages 1-12 mcg/mg creatinine 95% Reference Range B-Complex Vitamin Markers (B1, B2, B3, B5, B6, Biotin) a-ketoisovalerate 0.16 <= a-ketoisocaproate 0.12 <= a-keto-ß-methylvalerate 0.23 <= Xanthurenate 0.21 <= ß-Hydroxyisovalerate 6.0 <= 22.5 Methylation Cofactor Markers (B12, Folate) Methylmalonate 0.7 <= Formiminoglutamate 0.1 <= 3.2 Cell Regulation Markers Neurotransmitter Metabolism Markers (Tyrosine, Tryptophan, B6, antioxidants) Vanilmandelate Homovanillate 3.2 L Hydroxyindoleacetate 2.1 L Kynurenate 0.9 <= Quinolinate 1.8 <= Picolinate 2.9 L Oxidative Damage and Antioxidant Markers (Vitamin C and other antioxidants) p-hydroxyphenyllactate 0.31 H <= Hydroxy-2-deoxyguanosine 1.7 <= 8.7 (Units for 8-hydroxy-2-deoxyguanosine are ng/mg creatinine) Florida Clinical Lab Lic. # Page 2

6 Ordering Physician: Reprinted: 05/23/2013 This report is not intended for the diagnosis of neonatal inborn errors of metabolism. Results Ranges are for ages 1-12 mcg/mg creatinine Toxicants and Detoxification 95% Reference Range Detoxification Indicators (Arg, NAC, Met, Mg, antioxidants) Methylhippurate <= Orotate 0.27 <= Glucarate 10.1 H <= a-hydroxybutyrate 0.35 H Pyroglutamate 115 H Sulfate 958 L Compounds of Bacterial or Yeast/Fungal Origin Bacterial - general 36. Benzoate <DL* 2.1 <= <= Hippurate 164 <= Phenylacetate <DL* <= Phenylpropionate <DL* <= p-hydroxybenzoate <DL* <= p-hydroxyphenylacetate 6 <= Indican 29 <= Tricarballylate 0.18 <= 2.00 L. acidophilus / general bacterial D-Lactate 0.5 <= 5.6 Clostridial species 45. 3,4-Dihydroxyphenylpropionate Yeast / Fungal <DL* <= D-Arabinitol 38 <= 92 Creatinine = 190 mg/dl * <DL = less than detection limit ** >LIN = greater than linearity limit Florida Clinical Lab Lic. # Page 3

7 Ordering Physician: Reprinted: 05/23/2013 Supplement Recommendation Summary With knowledge of a patient's full medical history and concerns, the Organix Comprehensive Profile laboratory results may be used to help healthcare professionals create an individually optimized nutritional support program. Based strictly on the results from this test, the summary table below shows estimates of nutrient doses that may help to normalize nutrient-dependent metabolic functions. The dosage recommendations are for children 6 to 12. Further adjustments for body weight may be needed. Customized Vitamin and Mineral Formulation Nutrients listed in this section are normally contained in a multi-vitamin preparation. "Base" amounts may be used to ensure health even when no abnormalities are found. Customized preparations of the multi-vitamin/mineral formula shown below may be produced by compounding pharmacies. Nutrient Vitamin A* B-Carotene* Vitamin C Vitamin D* Vitamin E Vitamin K* Thiamin (B1) Riboflavin (B2) Niacin (B3) Pyridoxine (B6) Folic Acid (or 5-Methyl-THF) Vitamin B12 Biotin Pantothenic Acid (B5) Calcium citrate Iodine* Magnesium Zinc* Base 1250 IU 2750 IU 125 mg 200 IU 50 IU 50 mcg 2.5 mg 2.5 mg 12.5 mg 7.5 mg 200 mcg 25 mcg 50 mcg 12.5 mg 250 mg 37.5 mcg 125 mg 7.5 mg Daily Amounts Units Added 1000 mg 200 IU Selenium 50 mcg 25 mcg Copper 0.5 mg Manganese* 2.5 mg Chromium 100 mcg Molybdenum* 12.5 mcg Boron* 0.5 mg * Nutrients with an asterisk are not modified based on the Organix test results. MM01 Florida Clinical Lab Lic. # Page 4

8 Ordering Physician: Reprinted: 05/23/2013 Other Items Indicated for individual supplementation Various conditionally essential nutrients and other potentially beneficial interventions appear in this section only if relevant abnormalities are present. These ingredients are not included in the customized vitamin formula on the previous page. The dosage recommendations are for children 6 to 12. Further adjustments for body weight may be needed. Nutrient 5-Hydroxytryptophan Arginine Glycine Lipoic Acid N-Acetylcysteine Need for other antioxidants Tyrosine Amount 100 mg 250 mg 2000 mg 50 mg 400 mg Moderate 250 mg Florida Clinical Lab Lic. # Page 5

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