BIOLOGY 12 NOVEMBER 2000 STUDENT INSTRUCTIONS

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1 Place Personal Education Number (PEN) here. Place only pre-printed PEN label here. STUDENT INSTRUCTINS 1. Place the stickers with your Personal Education Number (PEN) in the allotted spaces above. Under no circumstance is your name or identification, other than your Personal Education Number, to appear on this booklet. 2. Ensure that in addition to this examination booklet, you have an Examination Response Form. Follow the directions on the front of the Response Form. 3. Disqualification from the examination will result if you bring books, paper, notes or unauthorized electronic devices into the examination room. 4. When instructed to open this booklet, check the numbering of the pages to ensure that they are numbered in sequence from page one to the last page, which is identified by ENDÊFÊEXAMINATIN. BILGY 12 NVEMBER 2000 CURSE CDE = BI Place only hand-printed PEN here. 5. At the end of the examination, place your Response Form inside the front cover of this booklet and return the booklet and your Response Form to the supervisor. Ministry use only Ministry of Education

2 Question 1: 1.. (6) Question 2: 2.. (6) Question 3: 3.. (6) Question 4: 4.. (8) Question 5: 5.. (10) Question 6: 6.. (5) Question 7: 7.. (7) Question 8: 8.. (2)

3 BILGY 12 NVEMBER 2000 CURSE CDE = BI

4 GENERAL INSTRUCTINS 1. Electronic devices, including dictionaries and pagers, are not permitted in the examination room. 2. All multiple-choice answers must be entered on the Response Form using an HBÊpencil. Multiple-choice answers entered in this examination booklet will not be marked. 3. For each of the written-response questions, write your answer in ink unless otherwise instructed in the space provided in this booklet. 4. Ensure that you use language and content appropriate to the purpose and audience of this examination. Failure to comply may result in your paper being awarded a zero. 5. This examination is designed to be completed in two hours. Students may, however, take up toê30 minutes of additional time to finish.

5 BILGY 12 PRVINCIAL EXAMINATIN 1. This examination consists of two parts: Value Suggested Time PART A: 50 multiple-choice questions PART B: 8 written-response questions Total: 100 marks 120 minutes

6 THIS PAGE INTENTINALLY BLANK

7 PART A: MULTIPLE CHICE Value: 50 marks INSTRUCTINS: Suggested Time: 45 minutes For each question, select the best answer and record your choice on the Response Form provided. Using an HB pencil, completely fill in the circle that has the letter corresponding to your answer. Use the following diagram to answer question The organelle above is A. a nucleolus. B. a mitochondrion. C. a Golgi apparatus. D. an endoplasmic reticulum VER

8 Use the following diagram to answer question 2. X 2. ne function of structure X is to A. replicate DNA. B. produce amylase. C. transcribe mrna. D. hydrolyze nuclease. Use the following diagram to answer question 3. X W Y Z 3. Which of the structures manufactures rrna? A. W B. X C. Y D. Z - 2 -

9 4. A solution with a high concentration of hydrogen ions ( H + ) is A. basic. B. acidic. C. neutral. D. isotonic. 5. Which of the following is produced when glucose and fructose are chemically joined to form sucrose? A. water B. nucleotide C. peptide bond D. hydrogen bond 6. Which diagram illustrates an energy storage product of the liver? A. CH 2 CH 2 CH 2 CH 2 B. CH 3 H CH 3 C. D. P VER

10 7. Which of the following is the correct matching of base pairs in DNA? A. cytosineñguanine; uracilñadenine B. cytosineñadenine; thymineñuracil C. adenineñguanine; cytosineñthymine D. adenineñthymine; guanineñcytosine 8. Which of the following is a component of a DNA molecule? A. ATP B. uracil C. ribose D. nucleotide 9. In DNA replication, the term ÒunzippingÓ refers to A. denaturing the DNA helix. B. unwinding the mrna from the DNA after transcription. C. breaking the bonds between complementary DNA strands. D. breaking the bonds between the sugar and phosphate molecules. 10. Which of the following is a valid contrast between RNA and DNA? RNA DNA A. helical not helical B. sugar is ribose sugar is deoxyribose C. found only in the nucleus found in the nucleus and the cytoplasm D. thymine is one of its bases uracil is one of its bases 11. Transcription is the production of A. a polypeptide chain. B. a new DNA molecule. C. multiple copies of a single type of enzyme. D. an RNA molecule complementary to a section of DNA

11 Use the following chart to answer questions 12 and 13. Three-letter codons of messenger RNA and the amino acids specified by the codons AAU AAC Asparagine CAU CAC Histidine GAU GAC Asparatic acid UAU UAC Tyrosine AAA AAG Lysine CAA CAG Glutamine GAA GAG Glutamate UAA UAG Stop ACU ACC ACA ACG Threonine CCU CCC CCA CCG Proline GCU GCC GCA GCG Alanine UCU UCC UCA UCG Serine AGU AGC AGA AGG Serine Arginine CGU CGC CGA CGG Arginine GGU GGC GGA GGG Glycine UGU UGC UGA UGG Cysteine Stop Tryptophan AUU AUC AUA AUG Isoleucine Methionine CUU CUC CUA CUG Leucine GUU GUC GUA GUG Valine UUU UUC UUA UUG Phenylalanine Leucine 12. Read the following DNA sequence left to right. Which amino acid sequence is coded for? A. tyrosine, valine B. isoleucine, valine C. tyrosine, glutamate D. isoleucine, glutamate TATCTT 13. If a cell grown in the presence of radioactively-labelled uracil is actively producing protein containing lysine, which of the following is correct? A. The lysine produced is radioactive. B. The codons for lysine are radioactive. C. The DNA code for lysine is radioactive. D. The anticodons for lysine are radioactive VER

12 14. Disorganized and uncontrolled cell growth is called A. anaplasia. B. metastasis. C. vascularization. D. contact inhibition. 15. Which of the following is not one of the recognized Òseven danger signalsó that may indicate the presence of cancer? A. headache B. persistent cough C. a sore that will not heal D. change in a moleõs appearance 16. During carcinogenesis, an initiator A. triggers metastasis. B. promotes vascularization. C. brings about DNA mutation. D. provides an environment for tumour formation. 17. A virus may be able to bring about carcinogenesis since it can A. denature DNA. B. add a gene to the host cell. C. reproduce within the host cell. D. cause the death of its host cell. 18. The movement of an oxygen molecule throughout a cell occurs by A. osmosis. B. diffusion. C. pinocytosis. D. facilitated transport

13 Use the following diagram to answer question 19. time 19. Which of the following situations is an example of the process shown above? A. the absorption of glucose by the cell B. red blood cells moving in the bloodstream C. the excretion of hydrogen ions in the kidney D. the secretion of neurotransmitters at the synapse VER

14 Use the following diagram to answer questions 20 and 21. Side A (solution 1) Side B (solution 2) membrane 20. The diagram shows two solutions containing solutes and dissolved in water and separated by a membrane. If the membrane is only permeable to water, which of the following will occur? A. will move from side A to side B. B. The concentration of on side A will increase. C. The concentration of on side B will increase. D. Final amounts of, and water will be equal on each side. 21. If the membrane is permeable to but not to or water, side A will A. swell and possibly burst. B. become isotonic to side B. C. remain hypertonic to side B. D. become hypotonic to side B

15 Use the following diagram to answer question 22. X 22. The structure labelled X is the A. appendix. B. epiglottis. C. duodenum. D. gall bladder. 23. Which of the following is not a function of the liver? A. producing bile B. secreting insulin C. detoxifying blood D. making blood proteins VER

16 Use the following diagram to answer question 24. X 24. The vessel labelled X is the A. aorta. B. renal vein. C. hepatic vein. D. hepatic portal vein. 25. Which of the following is normally found in blood plasma but not in lymph? A. salt B. urea C. oxygen D. platelets

17 Use the following diagram to answer question 26. X 26. If osmotic pressure is a constant 25 mm Hg, which of the following best describes what occurs at X? EVENT BLD PRESSURE (mm Hg) A. nutrients move from the capillaries to the tissues 10 B. nutrients move from the capillaries to the tissues 40 C. wastes move into the capillaries from the tissues 25 D. wastes move into the capillaries from the tissues VER

18 Use the following diagram to answer questions 27 and 28. X Y 27. Structure X carries blood to the A. lungs. B. heart tissue. C. lower body. D. upper body. 28. Structure Y is the A. septum. B. right ventricle. C. coronary artery. D. chordae tendineae

19 Use the following diagram to answer question 29. Y Z X W 29. In which of the following structures are cilia found? A. W B. X C. Y D. Z VER

20 Use the following graph to answer question 30. pressure in thoracic cavity X time Y 30. The graph shows changes in air pressure in the thoracic cavity during breathing. Which of the following occurs between times X and Y? A. rib muscles relax and diaphragm relaxes B. rib muscles relax and diaphragm contracts C. rib muscles contract and diaphragm relaxes D. rib muscles contract and diaphragm contracts

21 Use the following graph to answer question membrane potential (millivolts) Ð65 X Y time (milliseconds) 31. What occurs within the neuron between time X and time Y? A. Sodium ions move into the cell. B. Calcium ions move out of the cell. C. Potassium ions move out of the cell. D. Large, negatively-charged ions move into the cell. 32. Resting potential is characterized by A. the opening of the sodium gates. B. more potassium ions outside the membrane than inside. C. an equal number of sodium ions on both sides of the membrane. D. more sodium ions on the outside than on the inside of the membrane VER

22 Use the following diagram to answer question The event that occurs next is the movement of A. sodium ions ( Na + ) into the post-synaptic neuron. B. calcium ions ( Ca 2+ ) into the pre-synaptic ending. C. potassium ions ( K + ) out of the post-synaptic ending. D. bicarbonate ions ( HC 3 ) into the receptors of the pre-synaptic membrane. Use the following diagram to answer question 34. X W Y Z 34. Which of the following structures sorts incoming sensory stimuli and channels them to the appropriate part of the brain? A. W B. X C. Y D. Z

23 35. The hypothalamus causes the anterior pituitary to secrete hormones by A. negative feedback. B. releasing adrenalin. C. releasing hormones. D. nervous stimulation. 36. Which of the following is a true statement about the collecting duct? A. Water diffuses into it. B. It responds to aldosterone. C. It is the site of tubular excretion. D. The fluid in it becomes hypertonic to blood. 37. In the nephron, the highest concentration of salt is found surrounding the A. loop of Henle. B. BowmanÕs capsule. C. distal convoluted tubule. D. proximal convoluted tubule. Use the following diagram to answer question 38. X 38. During the process occurring at X, some nutrients are separated from A. salts. B. water. C. wastes. D. proteins VER

24 39. The concentration of urea is lower in the renal vein than in the renal artery because A. the kidneys add urea to the blood. B. little reabsorption of urea occurs in the nephron. C. BowmanÕs capsule removes water from the filtrate. D. the peritubular capillary network passes urea to the loop of Henle. Use the following diagram to answer question 40. X Y W Z 40. Which of the following glands produces aldosterone? A. W B. X C. Y D. Z

25 Use the following diagram to answer question 41. W X Y Z 41. In which of the following structures does sperm maturation occur? A. W B. X C. Y D. Z 42. The cells of the seminiferous tubules respond to A. luteinizing hormone (LH) and produce sperm. B. luteinizing hormone (LH) and produce testosterone. C. follicle-stimulating hormone (FSH) and produce sperm. D. follicle-stimulating hormone (FSH) and produce testosterone. 43. ne function of seminal fluid is to A. lower the ph of the uterus. B. lower the ph of the vagina. C. provide nourishment for the egg. D. provide a medium in which sperm swim VER

26 44. Which part of a mature sperm aids digestion of the outer membrane of an ovum? A. tail B. head C. acrosome D. mid-piece 45. Increased muscle strength, enlarged vocal cords and growth of pubic hair are stimulated by A. thyroxin. B. estrogen. C. testosterone. D. follicle-stimulating hormone (FSH). 46. The hormone that stimulates the secretion of sex hormones in both sexes is A. estrogen. B. testosterone. C. luteinizing hormone (LH). D. human chorionic gonadotropin (HCG)

27 Use the following diagram to answer question 47. W X Y Z 47. In which of the labelled structures is an egg produced? A. W B. X C. Y D. Z 48. The function of the corpus luteum is to A. help maintain the endometrium. B. secrete luteinizing hormone (LH). C. produce human chorionic gonadotropin (HCG). D. produce more follicle-stimulating hormone (FSH). 49. Days 15 to 28 of the 28-day uterine cycle are referred to as the A. luteal period. B. secretory phase. C. menstrual period. D. proliferative phase VER

28 Use the following graph to answer question 50. Uterine Cycle thickness of endometrium days 50. The increased production of what hormone causes the change shown in the graph on or about day 5? A. estrogen B. oxytocin C. progesterone D. luteinizing hormone (LH) This is the end of the multiple-choice section. Answer the remaining questions directly in this examination booklet

29 PART B: WRITTEN RESPNSE Value: 50 marks INSTRUCTINS: Suggested Time: 75 minutes 1. Use a pen for this part of the examination unless otherwise instructed. 2. Write your answers in the space below the questions. 3. rganization and planning space has been incorporated into the space allowed for answering each question. 4. You may not need all of the space provided to answer each question. Use the following diagrams to answer question 1. Cell A Cell B 1. Cell A is found lining the proximal convoluted tubule of the nephron. Cell B is found in the liver. Identify three visible differences between the two cells and explain how each difference aids the cell in carrying out its specific functions. (6 marks: 2 marks each) Difference 1: Explanation: Difference 2: Explanation: Difference 3: Explanation: VER

30 2. Levels of protein structure differ according to the types of bonds that hold them together. As an enzyme is synthesized, these bonds form to give the protein its final 3-dimensional shape. For each of the following diagrams, name the level of protein structure and describe the type of bonding responsible. (6 marks: 1 mark each for level; 1 mark each for description) C N H N H N H C N N C C C C C C C C C C C C C C C C C C C C N N N C H H H N C N N N H N H Level of protein structure: Description of bonding: Level of protein structure: Description of bonding:

31 H C C N R H C H R C H N H C R C N H Level of protein structure: Description of bonding: VER

32 3. What effect would each of the following changes have on the rate of an enzyme-catalyzed reaction occurring in the stomach? Give an explanation for the effect. a) The temperature is increased from 35 C to 37 C. (2 marks) b) A competitive inhibitor is added. (2 marks) c) The ph is increased from 3 to 8. (2 marks)

33 4. Identify four substances produced by the pancreas and give one function of each. (8 marks: 1 mark each for substance; 1 mark each for function) Substance 1: Function: Substance 2: Function: Substance 3: Function: Substance 4: Function: VER

34 5. a) The average resting blood pressures and blood velocities were measured in various blood vessels of an individual as shown in the table below. Identify the type of blood vessel in the space provided. (5 marks) BLD VESSEL AVERAGE BLD VELCITY (cm/s) AVERAGE BLD PRESSURE (mm Hg) TYPE F BLD VESSEL A B C D E b) Explain the observed blood pressure and velocity in the following vessels. Vessel A: (2 marks) Vessel B: (2 marks) c) How does the sympathetic nervous system raise blood pressure? (1 mark)

35 6. a) During external respiration, reactions involving gases occur in the capillaries. Describe three of these reactions. (3 marks) i) ii) iii) b) Describe two conditions in the capillaries during external respiration that affect the rate of the reactions above. (2 marks) i) ii) VER

36 Use the following diagram to answer question a) Label the diagram above using the numbers of the terms listed below. (Not all the terms will be used.) (2 marks: 1 2 mark each) 1. axon 2. dendrite 3. synapse 4. node of Ranvier 5. cell body 6. receptor b) Describe how a reflex arc functions. (5 marks)

37 8. Name two substances that are actively excreted during the process of tubular excretion. (2 marks) i) ii) END F EXAMINATIN

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