Course: Biology Out of Balance. Module 1: Pathophysiology of the Liver and Detoxification 1.5 CEU-NCCAOM. Instructor: Debi Rene Weiss, LAc.

Transcription

1 Course: Biology Out of Balance Module 1: Pathophysiology of the Liver and Detoxification 1.5 CEU-NCCAOM Instructor: Debi Rene Weiss, LAc., RN

2 Debi Weiss, R.N., Lic. Ac., Director of Transition to Health, Minneapolis, MN Originator of the Ideal Weight Program

3 Liver Physiology Liver-Gut Axis: Biotransformation Liver-Gut Axis: Immunological Response Toxicity Sources Symptomology Liver Pathophysiology Phase I & II pathways Detoxification Protocols Nutritional Herbal/neutraceuticals Clay Rebounding Acupuncture Microcurrent/Color

4 Simple Questions, ch. 8: The Liver is like an army s general from whom the strategy is derived. Directs Qi Stores Blood Controls Sinews Manifests in the nails Opens into the eyes Houses Ethereal Soul

5 Hepar- or hepat: Greek meaning root 500 functions major role in metabolism Hepatocytes: (Gut-Liver Axis) Detoxification Protein synthesis Produces biochemicals for digestion Kupffer Cells: (Gut-Immune Axis) Immunologic response Produces bile: stored in Gall Bladder Filters 2 quarts of blood per minute

6 75% of blood received into the liver is venous delivered via the portal vein directly from GI system Filtration of toxins is absolutely critical, as the blood from the intestines contains high levels of toxic substances. Hepatocytes transform gut-derived compounds into safe by-products then directs them to the Bile for excretion or into arterial blood circulation

7 Kupffer cells: phagocytes (think Pac Man) Clear portal system of circulating debris Limit entry of bacterial toxins and endotoxins into systemic circulation Always in a state of low-grade alert Exaggerated Immune Response Leaky Gut Impaired hepatic clearance

8 Toxin: substance that precipitates an immune reaction Ingestion Inhaled Topical Immune system tolerance: Views toxin as not self therefore dangerous Directly damage structure & function of cells Strains liver detoxification system

9 Heavy metals: mercury, lead, arsenic Chemicals: PCB s, dioxins Pesticides Plastics: BPA Drinking water: toxic run-off, prescriptions Non-organic animal consumption GMO s Xenobiotics Endotoxins: gut bacteria, yeast, parasites

10 212 chemicals typically found Widespread exposure: industrial chemicals Updated September chemicals not previously reported 201 tables updated 49 chemicals added currently 250 chemicals listed 770 pages

11 Body Burden: The Pollution in Newborns 2005 report on 10 newborn s cord blood Tested for industrial chemicals Found 287 total, 200 average/baby 47 common consumer product chemicals 212 banned or severely restricted chem. 28 waste byproducts 180/287 carcinogens (human or animal) 217/287 toxic to brain & nervous system 208/287 cause birth defects or abnormal development (animal tests)

12 PHASE 1 CYTOCROME P450 Modification: fat soluable toxins drugs steroid hormones Require: oxygen vit. B, C, E glutathione antioxidants I N T E R M E D I A R Y M E T A B O L I T E S Free Radicals Antioxidants PHASE 2 CONJUGATION Conjugation: I.M. transformed water soluable excrete via stool/urine Require: amino acids *glutamine phytochemicals

13 Brain fog poor focus/concentration Fatigue exhaustion Body aches - headaches Sensitivity to odors Digestive issues: bloating, nausea Tingling of extremities Weight gain - difficulty losing weight Feeling heavy, puffy, swollen Depression, irritability, apathy

14 Liver Qi Stagnation Liver Blood Stasis Liver-Fire Liver-Wind Damp-Heat in Liver-Gall Bladder Deficiency of Liver-Blood Liver Yang Rising Liver Invading Spleen Liver Invading Stomach

15 Qi Stagnation-distention, n/v, belching, gas, appetite changes, diarrhea, constipation, cramps, bitter taste, melancholy, irritability, impatience, PMS, irregular periods, pain Liver Blood-vomiting Blood, clots, headaches, floaters, menstrual >/<, muscle weakness Liver Wind/Fire-dizziness, tics, tremors, numbness, tinnitus, red eyes, high temp Damp-discharges, itching, dark urine,

16 Detoxification Questionnaire Part 1: Medical Symptom Questionnaire (MSQ) measures minimal/moderate/elevated toxic load Part 2: Xenobiotic Tolerability Test (XTT) A chemical compound (as a drug, pesticide, or carcinogen) that is foreign to a living organism

17 Nutritional Herbal/neutraceutical Clay Rebounding Acupuncture Microcurrent Color

18 Functional Medicine resources: Drs. Susan Blum, Mark Hyman, Diana Schwarzbein Complete Detox Elimination Diet days Gluten, dairy, soy, corn, peanuts, oranges Processed foods-sugar, trans-fats Alcohol, caffeine, coffee, chocolate Incorporate Healing Foods Support Phase I & II: Vit. A, B s, C, phytonutrients Reduce Inflammation: Omega 3 s Heal Gut: Vit. A, zinc, antioxidants, fermented Blood Sugar: all of the above

19 Support Phase 1-2 Detox Pathways Advaclear: Metagenics Liver Formulas Healthy Liver Formula: herbal tincture (HerbPharm) Cell Food: 8 drops/8 oz. H2O/3 X day Generates bio-available O2 Reduces free radicals Eliminaid: stellar bowel formula

20 Glutathione, alpha lipoic acid Zinc Green algae Soluble fiber PGX: Natural Factors (pgx.com) Clay baths/foot soaks, internal ingestion magneticclay.com Practitioner supervised chelation

21 Needak rebounders Improves digestion Improves elimination of cellular waste Accelerates metabolism Increases O2 uptake Increases cellular respiration Promotes detox via lungs, skin, lymph Does not stress joints 2 minutes of rebounding flushes lymphatics

22 Microcurrent Pads: Ch.A: Liv-13 Ch.B: CV 12-6 Intensity ~ uA Ch.A: 50, 40, 284, 57, 49 / Ch.B: 35 (13, 38) 5-7 minutes per frequency Acupuncture: Bilateral: ST-25,36, Sp-15, K-14, SJ-5, GB-41 Auricular: Shen men, Point zero, Liver Yin tang

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25 Cell Food Lumina Health luminahealth.com Rebounders Needak needak-rebounders.com Clay L L Magnetic Clay magneticclay.com Energique (Eliminaid) Emerson Ecologics emersonecologics.com