NUTRI ENDO 1 & 2. A scientific breakthrough for Endometriosis

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1 NUTRI ENDO 1 & 2 A scientific breakthrough for Endometriosis

2 ENDOMETRIOSIS Key figures 1 in 10 women of childbearing age million women in Europe 40 % of women with endometriosis have difficulty conceiving. The mean recurrence rate after surgery is about 20 % after 5 years Impaired quality of life Precursory signs Pelvic pain Risk of endometriosis Doctor Chrysoula Zacharopoulou, Gynaeologist, Hôpital de Tenon Obstetrics Department- Paris Age (between 25 and 40 years old) Family history Nulligests (women who have never been pregnant) Genital anomalies (stenosis and septate vagina, etc.) Risk factors

3 ENDOMETRIOSIS Change in normal physiological function Displaced endometrium OVULATION Embryo cells unable to implant Displacement of endometrium (ectopic endometrium) Irregular cycle Loss of endometrial cell membrane equilibrium Increased angiogenesis (VEGF) Other environmental epigenetic factors (DNMT3L enzyme)

4 ENDOMETRIOSIS Depth and location Uterine wall Fallopian tubes Bladder Ovaries Peritoneum Colon Peritoneum Ovaries Fallopian tubes Uterine wall Bladder Rectum Colon More rarely: Small bowel, vulva, vagina and sometimes even the lungs Complications Cysts Infertility Sterility Elevated activin

5 Painful and debilitating symptoms Symptoms not to be ignored Dysmenorrhoea Metrorrhagia Dyspareunia Hematuria Rectorragia Limited treatments Treatment for endometriosis consists of a combination of medication hormones, anti-inflammatories and pain relief, etc. and surgery At the present time, there is no cure for endometriosis

6 For use by Nutrilab only Trace metals for the endometrium Trace metal deficiency Abnormal insertion of cells in the uterine endometrium A specially formulated trace metal complex to give women a targeted response to this imbalance Maintain, regulate and optimise the natural balance in the area

7 NUTRI ENDO 1 & 2 Clinically tested solution According to the revised American Fertility Society (rafs) classification, there are 4 stages of endometriosis: T1 T2 T3 T4 Stage 1 or minimal, scores de 1 to 5 Stage 2 or mild, scores 6 to 15 Stage 3 or moderate, scores 16 to 42 Stade 4 or severe for scores over 42 CRDT Scientific and Technical Research Organisation 2010 Open clinical study in 10 women with documented endometriosis. NUTRI ENDO tested over 60 days 100 % REDUCTION in symptoms 50 % TOTAL DISAPPEARANCE of symptoms

8 NUTRI ENDO 1 & 2 Targeted response The menstrual cycle is an important event in all women s lives, full of promise Endometrium in right place OVULATION Normal hormonal cycle Endometrium correctly placed Regulation of apoptosis Harmonious angiogenesis

9 NUTRI ENDO 1 & 2 Targeted response Clinically proven results Pain Symptoms No side effects Compliance and safety An effective and natural solution Suggested use Reduce symptoms FIRST 2 MONTHS NUTRI ENDO 1 One sequence in the morning NUTRI ENDO 2 One sequence in the evening Consolidate the effects Prevent recurrence FOLLOWING 2 MONTHS NUTRI ENDO 1 One sequence in the morning NUTRI ENDO 2 One sequence in the evening Daily cost: One 10 tablet sequence 9 10 To be chewed and then swallowed one tablet at a time, once a day and in the given order, tablets 1 to 10 in the series. 7 day course per blister Take the tablets in order, starting with No. 1, then No. 2, 3 etc. up to No. 10. You have taken a full dose when you have chewed and swallowed tablet No. 10. Information on the back of the blister strip.

10 NUTRI ENDO 1 & 2 In practice 2 sequences of 10 chewable tablets per day No side effects Composition NUTRI ENDO 1 Composition : Calcium mg Magnesium mg Zinc mg Manganese mg Potassium mg Sodium mg Copper µg Iron µg RDI: Recommended Daily Intake 2.7 % RDI 1.2 % RDI 8,0 % RDI 5.5 % RDI < 0.1 % RDI % RDI < 0.1 % RDI Other ingredients: Lactose, Sorbitol, Magnesium stearate. Trace metals: Zinc acetate, Calcium carbonate, Magnesium carbonate, Manganese carbonate, Sodium carbonate, Calcium chloride, Magnesium chloride, Copper gluconate, Iron gluconate, Manganese gluconate, Potassium gluconate, Zinc gluconate, Sodium iodide, Trimagnesium phosphate, Zinc sulphate. NUTRI ENDO 2 Composition : Calcium mg Magnesium mg Zinc mg Manganese mg Potassium mg Copper µg Iron µg Sodium mg RDI: Recommended Daily Intake 2.8 % RDI 1.5 % RDI 5,4 % RDI 9.0 % RDI < 0.1 % RDI 5.2 % RDI < 0.1 % RDI - Other ingredients: Lactose, Sorbitol, Magnesium stearate. Trace metals: Calcium carbonate, Magnesium carbonate, Manganese carbonate, Calcium chloride, Sodium chloride Copper gluconate, Manganese gluconate, Potassium gluconate, Zinc gluconate, Sodium iodide, Tricalcium phosphate, Trimagnesium phosphate, Zinc sulphate, Iron sulphate. Eagerly awaited prescription