Orthopaedics Business. Dave Illingworth, President February

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1 Orthopaedics Business Dave Illingworth, President February

2 Smith & Nephew Orthopaedics Attractive market Strong performance Momentum 2

3 Attractive market Demographics - 2x Growth by 2020 Active people - Penetration/Younger - Better informed - Treatment alternatives Price / Mix - DRG up 3% in 05 - Opportunity for mix shift Growth rate in the teens! Focus on healthcare economics growing! 3

4 2004 performance highlights Industry-leading global sales growth at 17%*, 22% in the US BIRMINGHAM hip resurfacing adds 4% to growth Market share gains in all segments New product momentum continues: 18% of sales from new products Operating margin improvement OXINIUM GENESIS II Knee Femoral *Underlying sales growth is sales calculated by eliminating the effects of translational currency and MMT acquisition 4

5 2004 Sales growth* comparison 25.0% 20.0% Fastest growing for the fifth year in a row 15.0% 10.0% Average market growth 5.0% 0.0% Stryker Biomet Synthes DePuy Zimmer S&N * Growth in served markets, measured in constant currency Impact of BIRMINGHAM hip resurfacing 5

6 Momentum in Orthopaedics Five years of industry leading sales growth Sales focus, specialization and productivity Unique technology OXINIUM technology Innovative product pipeline BIRMINGHAM Hip Resurfacing EXOGEN bone stimulation SUPARTZ joint fluid therapy BIRMINGHAM Hip Resurfacing Not approved for use in U.S. 6

7 Momentum in Recon Active people - Advanced bearings - Expanding demographics - MIS / CAS OXINIUM Unicompartmental New products - ¼ of our business GENESIS II OXINIUM Knee CAS Knee 7

8 Momentum in Recon Advance bearing surfaces Only company to offer all the options Metal on Cross-Linked Poly Metal-on-Metal Ceramic-on-Ceramic Strengths Head size and neck options Toughness Reduces wear Head size options Toughness Reduces wear Abrasion resistance Low friction Weakness Head scratches Liner options Abrasion sensitivity Liner options Limited size options Fracture OXINIUM on XLPE ALL NONE Most options and the best option: OXINIUM 8

9 Momentum in Recon Expanding demographics BIRMINGHAM Hip Resurfacing Low wear, range of motion, highly stable Patient demand #1 Hip resurfacing in world BIRMINGHAM Hip Resurfacing Not approved for use in U.S. ACCURIS OXINIUM Uni Knee Only Uni with OXINIUM >50% penetration (U.S.) Utilizes innovative ACCURIS instrumentation and techniques ACCURIS OXINIUM Unicompartmental Knee 9

10 Momentum in Recon MIS / CAS Patient Preference Techniques and training match surgeon preferred approach - Hips: anterior, posterior and direct lateral - Knees: mini-mid vastus AchieveCAS Standardization Computer Assisted becoming part of the landscape - AchieveCAS MIS Hip - AchieveTKAV2 Minimally Invasive Total Hip Instruments Minimally Invasive Total Knee 10

11 Momentum in Recon New products drive business Ceramic-on-Ceramic OXINIUM revision components PROFIX 5 in 1 knee instruments MIS Instrumentation GENESIS II MIS Tibial Base Plate PS High Flex Insert Ceramic-on-Ceramic OXINIUM GENESIS II Revision System 11

12 Momentum in Trauma Specialized sales force - for a specialized customer Medical education - meeting the surgeons needs New products - 1/4 of our business EXOGEN bone stimulation Clinical Therapies - dedicated and growing PERI-LOC Resident Education 12

13 Momentum in Trauma Specialized sales force Invest in sales force growth - 60 added in in total - 20% growth in 05 Trauma surgeon focused - Level 1 or 2 Trauma centers Trained as experts - Trauma only JET-X Mini Distal Radius Fixator Sales Training TRIGEN Nails 13

14 Momentum in Trauma Medical education Education - 65% increase in resident education - 2x number of CME courses - Mobile training center Sponsorship - OKO 5-year exclusive - Platinum Sponsor OTA - Diamond Sponsor OREF - Platinum Sponsor ACFAS Fellowships - Greater than 2x increase - Recognized leader in Circular Fixation fellowships 14

15 Momentum in Trauma New products drive business PERI-LOC IMHS CP (clinically proven) Asian IMHS TRIGEN Humeral Nail JET-X Wrist Fixation IMHS CP Asian IMHS PERI-LOC TRIGEN Humeral Nail 15

16 Momentum in Trauma Clinical Therapy focus Established dedicated unit - Focused on needs of the orthopaedic office and the Podiatric community - Experts in how bone heals at the cellular level Investment in sales force growth - >50% growth in 04 - Total size = % growth in 05 Investment in science - 19 papers at ORS, mechanism of action EXOGEN SUPARTZ 16

17 Smith & Nephew Orthopaedics Strategy is working Growth is accelerating Well-positioned for 2005 Continue investment 17

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