က လ မ မ သ စ န င ႔အတ မ နရ ခင ၾက င ႔ ဖစ ပၚလ သ ဆ က မ. Long- and Short-Term Effects of Institutional Care in the Bucharest Early Intervention Project
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1 က လ မ မ သ စ န င ႔အတ မ နရ ခင ၾက င ႔ ဖစ ပၚလ သ ဆ က မ Long- and Short-Term Effects of Institutional Care in the Bucharest Early Intervention Project
2 f vuf&sd urçmytajctae urçm teshutjym;&ds jykpkapmifha&smufa&; a[mrsm;wgif aexkdifcj hmuonfh uav;rsm;tay: avhvmqef;ppfcsuft& 44% aom uav;rsm;onf zghunzdk;ri aemufusri ESih f &ifqk dif BuKHawGU&jcif; bmompum; ESif h oifmum;avhvmqnf;yl;ri pgrf;aqmif&nf edrf husjcif; ausmif;oifcef;pm;rsm;ud k rvdkufed kifjcif; rdrdudk,fud k tm;udk;edkifpgrf; r&dsbj vlriaxmufyh hulndri &,lek difajc rsm;jcif; (Loman et al) 19 EdkifiHrS uav; 3800 ausmfay:wgif tajcchnyd; jykvkyfxm;aom avhvmri 75 ck\ tespfcskyfokh;oyfcsuft& rdbozg,f,m,d jykpkapmihfa&smufriatmufwgif BuD;jyif;cJhMuonf h uav;rsm; ESih ESdKif;,SOfygu ysrf;rqjcif;tm;jzifh OmPf&nf OmPfaoG; (IQ) 20 rswf edrf husjcif;/ (van Ijzendoom et al)
3 Bucharest pod;ydkif; umug,fa&; pdrhcsuf ESpf&SnfapmifhMunfhavhvmjcif; ckespfwgif pwif a[mrsm;odk Y pwifa&muf&dsvmaom uav;rsm;\ OD;aESmuf ESifh trltusifh zghunzdk;wdk;wufri tay: ppfaq;munfh&s kjcif; pod;yd kif; rs vuf&ds tcsdefxd uav;rsm;tm; pofqufrjywf vdkufvhtujcwfjcif; &kyfydkif;qkdif&m zghunzdk;jcif;? pof;pm;awg;ac:jcif;? pdwfvlria&;qkdif&mrsm; zghunzdk;jcif;? oha,mzof ESifh OD;aESmufzG HUNzdK;rIrsm; udk us,fjyefupgm avhvmjcif; Tulane University, University of Maryland, Boston Children s Hospital
4 ဂဟ သင တန က င မ တ င စ င ႔ ရ က မ အက ဆက မ က ယ ခ ၵ ၾက ထ မ
5 ခ ၵ က ယ ၾက ထ မ န မ ႔ က ၿခင က လ အသက အပ င ခ ၶ က ယ အ လ ခ န အရပ အၿမင ႔တ ႔တ င ဖ ႔ ၿဖ မ န က က ၿခင တ ႕ရသည Discover New Ways to Achieve Healthy Growth Bill & Melinda Gates Foundation Global Health Discovery and Nutrition
6 Z-Score Growth Failure in Institutionalized Children Height Weight -4 Rutter Johnson Mason L Miller Johnson Albers L. Miller L. Miller BEIP B. Miller
7 Baseline Growth BEIP Low Birth Weight Normal Birth Weight Controls Height Weight OFC Wt/Ht p <.05
8 Profound Growth Failure In Institutionalized Romanian Children n= (f) 3-19 y
9 Pubertal Development in Institutionalized Children Median Age of Onset (n=327) Breast Development Testicular Enlargment Pubic Hair Female Romanian Orphans US Controls Pubic Hair Male
10 11 y girl 14 y girl 17 y girl
11 Sequelae of Institutional Care Development စ တ ပ င ဖ ႕ ဖ မ
12 Brain Development 15.5 Weeks 22 Weeks 23 Weeks ~25 Weeks 27 weeks Full Term Adult Brain
13 Human Growth Brain Growth
14 BEIP-Bayley MDI (Mental Developmental index) at Baseline Institution Family p <.05
15 Family Institution 3-5 Hz 6-9 Hz Hz
16 EEG : Absolute Beta Power BEIP-8 Years μv Institution Family p <.05 Maturational lag in nervous system dependent ဥ က အ ရ ၾက ဖ ႕ ဖ မ န က က ခင လကၡဏ တရပ
17 Total Cortical Volume (cc) BEIP-Total Brain Volume at 8 Years Institution Family Grey Matter White Matter p <.05
18 ယ ၾကည မ လ အပ မ သ ယ ဇဥ စက ၀ င ပ ရ င မ စ တ ပ က မ
19 BEIP-Mental Health at 54 Months Institution Family Any Axis 1 Disorder p <.05 Any Emotional Disorder Any Behavioral Disorder
20 စ တ ခ စ မ က တ င တ သည စနစ စ တ ခ စ မ က ဖ ၿပခ က အတ င အတ သည စမ သပ မ ၿပ လ ပ During the episode, a female examiner introduced a pair of puppets to the child and acted out a conversation between them. The test is coded to identify discrete emotion behaviors as well as intensities of facial and bodily expressions of positive and negative emotions.
21 ထပ တလ လ လ ပ ဆ င မ မ (ဥပမ - လက မစ ပ ခင ) ထပ တလ လ ရည ရ ယ ခ က မ လ ပ ဆ င မ မ (လက မစ ပ ခင လက သည က က ခင ) ဥ ဏ ရည ဖ ႔ၿဖ မ န က က ခင Autism ၀ဒန ရ ခင တ ႕န င ႔ ဆက စပ သည ငယ စဥ က လမ ပတ ၀န က င မ လ ႕ ဆ ထ တ ႕မ နည ခင မမ န ကန ခင တ ႕ ၾက င ဖစ တတ သည
22 Motor Skills at 8 years Bruininks-Oseretsky Test of Motor Proficiency Institution Family Institution p <.05 Family ဂဟ မ သ စ
23 Speech Delay- စက ပ ခင Receptive Expression Emergent Language Scales (0-3 years) ( ဖၚ ပမ ) Expressive Receptive (လက ခ မ ) 20 0 Institution Family Institution Family Baseline အ ခခ 30 Months 30 လ p <.05
24 Speech Delay- စက ပ ခင Reynell Developmental Language Scales ( years) Institution Family Institution Family 30 Months 42 Months ( ဖၚ ပမ ) Expressive Receptive (လက ခ မ ) p <.05
25 Telomere န င ႔ ဂဟ တ င နထ င မ င အ မင ရင ရ မ စ စ စ သဆ မ တ ႕ င ဆက စပ ၾက င သက သ ပခ သည Bucharest Early Intervention Project Telomere length at 8 years of age was inversely related to the length of institutionalization.
26 ငယ စဥ ဘ၀တ င မ သ စ မ င မ နရ ခင ၾက င အ က ပ အခ က မ တ င သ သ စ အက သက ရ က မ ဖစ စ င သည ခ ၵ က ယ ဖ ႕ ဖ မ ဥ န က ဖ ႕ ဖ မ အရ ယ လ ပ ဆ င မ တည ဆ က ပ ဥ ဏ ရည ခ စ ခင တ ယ တ မ စ တ က န မ ရ အမ အက င ယ ၾကည မ အဆ မင မ က ယ တ အမ အရ ထပ တလ လ လ ပ ဆ င မ မ လ ပ ရ မ ဘ သ စက မ ရ ဗ ဇ ပ င လ မ
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