Acetylcholine Receptor Modulating Antibody

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1 Acetylcholine Receptor Modulating Antibody Order Name: ACETY MOD Test Number: TEST COMPONENTS REV DATE: 09/25/2012 Acetylcholine Receptor Modulating Antibody SEMI-FC Preferred 1 ml (0.5) Serum Clot Activator (Red Top, No-Gel) Refrigerated Alternate 1 ml (0.5) Serum Clot Activator SST (Red/Gray or Tiger Top) Refrigerated Special SST Clot tubes acceptable, however it is best if collected in non-gel clot tubes. stability: Room temperature: 2 hours; Instructions: Refrigerated: 2 weeks; Frozen: 1 year. Testing Schedule: Sun-Sat Expected TAT: 4-5 Days Clinical Use: Confirming the diagnosis of myasthenia gravis. Modulating autoantibodies to AChR cause weakness by inhibiting or modulating binding to the receptors. Cpt Code(s): 88182TC

2 Bordetella pertussis Antigen by Fluorescent Ab Order Name: C PERT FA Test Number: TEST COMPONENTS REV DATE: 09/17/2012 Bordetella pertussis Antigen by Fluorescent Ab FA Preferred See Information Swab Amies Blue Cap Swab in Charcoal Media Room Temperature Alternate See Information Nasal Wash Sterile Screwtop Container Room Temperature Special Instructions: Patient should have a persistent cough. Two PNP blue cap Amies Swabs in Charcoal media is preferred. Nasal wash is also acceptable. It is Preferred to have specimens to RML Main Lab within 24hrs for optimal stability. Testing Schedule: Sun-Sat Expected TAT: 2-4 Days Cpt Code(s): 87265

3 Bordetella pertussis Culture Order Name: C PERTUS Test Number: TEST COMPONENTS REV DATE: 09/17/2012 Bordetella pertussis Culture Cult Preferred See Information Swab Amies Blue Cap Swab in Charcoal Media Room Temperature Alternate See Information Nasal Wash Sterile Screwtop Container Room Temperature Special Instructions: Patient should have a persistent cough. Two PNP blue cap Amies Swabs in Charcoal media is preferred. Nasal wash is also acceptable. It is Preferred to have specimens to RML Main Lab within 24hrs for optimal stability. Testing Schedule: Sun-Sat Expected TAT: 7-14 Days Cpt Code(s): 87070

4 Bordetella pertussis Culture and Antigen by Fluorescent Ab Order Name: C PERTW/FA Test Number: TEST COMPONENTS REV DATE: 09/27/2012 Bordetella pertussis Antigen by Fluorescent Ab FA Bordetella pertussis Culture Cult Preferred See Information Swab Amies Blue Cap Swab in Charcoal Media Room Temperature Alternate See Information Nasal Wash Sterile Screwtop Container Room Temperature Special Instructions: Patient should have a persistent cough. Two PNP blue cap Amies Swabs in Charcoal media is preferred. Nasal wash is also acceptable. It is Preferred to have specimens to RML Main Lab within 24hrs for optimal stability. Testing Schedule: Sun-Sat Expected TAT: Culture:7-14 Days, FA: 2-4 Days Cpt Code(s): 87265, 87070

5 Catheter Tip (Intravascular) Culture Order Name: C TIP RT Test Number: TEST COMPONENTS REV DATE: 09/17/2012 Catheter Tip (Intravascular) Culture Cult Preferred See Information Catheter tip Sterile Screwtop Container Room Temperature Special This culture is for Intravascular Catheter tips, NOT Foley catheter tips. Instructions: Foley catheter tips are Not Suitable for any culture. Testing Schedule: Daily Expected TAT: 4 Days Clinical Use: Identifies pathogens or confirms sterility. Cpt Code(s): 87070

6 Coumadin/Warfarin Sensitivity (CYP2C9 & VKORC1 ) 3 Mutations Order Name: COUM POLYM Test Number: TEST COMPONENTS REV DATE: 09/25/2012 CYP2C9 ALLELE #1 PCR CYP2C9 ALLELE #2 PCR VKORC1 ALLELE #1 PCR VKORC1 ALLELE #2 PCR Warfarin Sensitivity Interpretation Preferred 4.5 ml (1mL) EDTA Whole Blood EDTA (Lavender Top) Refrigerated Testing Schedule: Mon, Thu Expected TAT: 5-7 Days Clinical Use: Coumadin/Warfarin Polymorphism: Identification of patient CYP2C9*2, CYP2C9*3, VKORC1 polymorphisms can help predict expected drug metabolism enzyme activity allowing clinicians to individualize drug treatment for each patient. Individualized therapy may assist patients by reducing adverse drug reactions and optimizing drug dose requirements. Notes: Methodology: Polymerase Chain Reaction/DNA Hybridization/Electrochemical Detection Cpt Code(s): 83891, 83892, 83900, 83901x13, 83912

7 Eastern Equine Encephalitis Virus IgG, IgM Order Name: EAST EQUIN Test Number: TEST COMPONENTS REV DATE: 09/11/2012 Eastern Equine Encephalitis Virus IgG IFA Eastern Equine Encephalitis Virus IgM IFA Eastern Equine Encephalitis Virus Interpretation Preferred 1mL(0.8) Serum Clot Activator SST (Red/Gray or Tiger Top) Refrigerated Special Stability: Room temperature: 7 Days, Refrigerated: 14 Days, Frozen: 30 Days Instructions: Testing Schedule: Mon-Fri Expected TAT: 2-4 Days Clinical Use: This highly sensitive test usually detects IgG and/or IgM antibody in acute specimens. Human infections are seasonal, from mid-summer to late summer, occurring from New England to Texas. Minimal crossreactivity with other Group A arboviruses (i.e., Western Equine Encephalitis virus) is observed. Cpt Code(s): 86652x2

8 Fetal Fibronectin Order Name: FETAL FIBR Test Number: TEST COMPONENTS REV DATE: 09/04/2012 Fetal Fibronectin SPI Preferred See Instructions Swab Adeza FFN Kit Refrigerated Special Stability: Room temperature: 8 hours, Refrigerated: 3 Days, Frozen: Not Recommended. Instructions: Use Full Term Adeza Biomedical Collection kit ONLY. (Kits available from Services. Store kits refrigerated) 1. The specimen should be obtained from the posterior fornix of the vagina during a speculum examination. The polyester tipped swab provided in the collection kit should be inserted into the vagina and lightly rotated across the posterior fornix for approximately 10 seconds to absorb the cervicalvaginal secretions. 2. Carefully remove the swab from the vagina and immerse the swab tip in the tube of buffer provided with the specimen collection kit. 3. Break the shaft (at the score) even with the top of the tube. Align the shaft with the hole inside the tube cap and push down lightly over the shaft, sealing the tube. 4. Label the tube with the patients name and any other identifying information required on the tube label. Patients with suspected or known placental abruption, placenta previa, or moderate or gross vaginal bleeding should not be tested for fetal fibronectin. Rejection criteria: s not collected in Adeza kit, Swabs contaminated with lubricant, soap, disinfectant, or cream (e.g. K-Y Jelly(R) lubricant, Betadine(R), disinfectant, Monistat(R) cream), Room temp samples received greater than 8hrs after collection, s received in expired transport. Frozen specimens are not recommended, and will be reported with a disclaimer. Testing Schedule: Sun-Sat (24/7) If STAT arrange for RML Courier pick up. Expected TAT: 1-2 Days Clinical Use: The rapid Fetal Fibronectin test is to be used as an aid in assessing the risk of preterm delivery in less than or equal to 7 or 14 days from the time of cervicovaginal sample collection in pregnant women with signs and symptoms of early preterm labor. Cpt Code(s): 82731

9 Mycobacterium tuberculosis (Respiratory) PCR Order Name: MTB NAA Test Number: TEST COMPONENTS REV DATE: 09/28/2012 Mycobacterium tuberculosis (Respiratory) PCR PCR Preferred 5mL(2mL) Bronchial lavage/wash Sterile Screwtop Container Refrigerated Alternate 5mL(2mL) Sputum Sterile Screwtop Container Refrigerated 5mL(2mL) Tracheal lavage/wash Sterile Screwtop Container Refrigerated Special For Respiratory s Only. Instructions: Early morning collection of sputum is preferred. 7mL(2mL) Bronchial lavage/wash, Tracheal lavage/wash or Sputum. Less than 2mL of specimen or grossly bloody specimens are causes for rejection. Keep refrigerated in a sterile screw cap container. Sputum specimens should not be frozen! Testing Schedule: Sun-Sat Expected TAT: 2-5 Days Notes: Performed at Oklahoma State Health Deptartment. Cpt Code(s): N/A

10 Nocardia Culture Order Name: C NOCARDIA Test Number: TEST COMPONENTS REV DATE: 09/18/2012 Nocardia Culture Cult Preferred See Instructions Swab Anaerobic Gel Swab (Blue Cap) Room Temperature Alternate See Instructions Swab Aerobic Swab (White Cap) Room Temperature See Instructions Respiratory specimen Sterile Screwtop Container Room Temperature Special Red Cap swabs and Respiratory specimens, Fluids and aspirates in sterile screwtop container also acceptable. Instructions: Testing Schedule: Sun-Sat Expected TAT: 28 Days Cpt Code(s): 87070

11 Rocky Mountain Spotted Fever (RMSF) IgG, IgM Order Name: RMSF IFA Test Number: TEST COMPONENTS REV DATE: 09/20/2012 Rocky Mountain Spotted Fever IgG Antibody IFA Rocky Mountain Spotted Fever IgM Antibody IFA Preferred 1 ml Serum Clot Activator SST (Red/Gray or Tiger Top) Refrigerated Testing Schedule: Mon - Fri Expected TAT: 3 Days Clinical Use: Assist in the diagnosis of Rocky Mountain Spotted Fever. The patient may not seroconvert until 10 days after onset of illness. Cpt Code(s): 86757X2

12 St. Louis Encephalitis Virus IgG, IgM Order Name: ST LOUIS A Test Number: TEST COMPONENTS REV DATE: 09/11/2012 St. Louis Encephalitis Virus IgG IFA St. Louis Encephalitis Virus IgM IFA St. Louis Encephalitis Virus Interpretation Preferred 1mL (0.5) Serum Clot Activator SST (Red/Gray or Tiger Top) Refrigerated Special Stability: Room temperature: Room temperature: 7 Days, Refrigerated: 14 Days, Frozen: 30 Days. Instructions: Pediatric minimum volume: 0.08mL Serum. Testing Schedule: Tues - Sat Expected TAT: 2-5 Days Clinical Use: IgG titers Greater than or Equal to 1:16 are suggestive of exposure while the presence of IgM indicates recent infection. Human infections are seasonal, from mid- to late-summer, occurring throughout the southern, southwestern, and west central states. Strong crossreactivity may be seen with other Group B arboviruses (Flavivirus) including Dengue, Japanese Encephalitis, Rio Bravo, Powassan, and Yellow Fever. Cpt Code(s): 86653x2

13 Vaginosis Profile from Swab (with Trichomonas Antigen) Order Name: V PROF SWB Test Number: TEST COMPONENTS REV DATE: 09/17/2012 Whiff test Amine Gram Stain MC Trichomonas Antigen EIA Vaginal Yeast Examination MC Clue Cell Examination MC Preferred See Instructions Swab BBL Red top culturette in Amies media (double swab) See Instructions Alternate See Instructions Swab BBL White top culturette swab (double swab) See Instructions Special Collect BBL Red top culturette in Amies media (double swab) or BBL White top culturette (double swab preferred) Instructions: Stability: 24hrs Room Temperature or 36hrs Refrigerated (Do Not Freeze). Samples contaminated with preparations containing iodine or by the immediate prior use of vaginal lubricants are not recommended. BBL Blue top swabs are Not Acceptable. Wet Prep collections are acceptable but not preferred. Testing Schedule: Sun-Sat Expected TAT: 1 Day Clinical Use: This vaginosis profile provides an interpretation of the types of vaginal pathology present: Yeast infections, Trichomonas vaginalis, Bacterial vaginosis and even Mixed Flora infections. The Trichomonas antigen along with gram stain and evaluation for yeast, clue cells, white blood cells and all bacterial types present. Whiff test (amine test) is reported as positive or negative. Notes: Created to handle extended transportation times seen with vaginosis profile specimens Cpt Code(s): 87205, 87808, 82120

14 Western Equine Encephalitis Virus IgG, IgM Order Name: WEST EQUIN Test Number: TEST COMPONENTS REV DATE: 09/11/2012 Western Equine Encephalitis Virus IgG IFA Western Equine Encephalitis Virus IgM IFA Western Equine Encephalitis Virus Interpretation Preferred 1mL(0.2) Serum Clot Activator SST (Red/Gray or Tiger Top) Refrigerated Special Stability: Room temperature: 7 Days, Refrigerated: 14 Days, Frozen: 30 Days Instructions: Testing Schedule: Mon-Fri Expected TAT: 2-4 Days Clinical Use: This highly sensitive test usually detects IgG and/or IgM antibody in acute specimens. Human infections are seasonal, from mid-summer to late summer, occuring throughout the western U.S. Minimal crossreactivity with other Group A arboviruses (i.e., Eastern Equine Encephalitis virus) is observed. Cpt Code(s): 86654x2

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