Generating evidence in rehabilitation: specific challenges and possible answers
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1 Generating evidence in rehabilitation: specific challenges and possible answers Thorsten Meyer School of Public Health University of Bielefeld Germany Joint Congress of DCRM, BNF-PRM, RBSPRM in Maastricht, Nov Trusted evidence. Informed decisions. Better health.
2 Disclosure of speaker s interests (Potential) conflict of interest None Disclaimer Views developed in this talk primarily represent the perspective of the speaker and - being on a conceptual level - are not directly related to empirical evidence.
3 Overview What is the background to the present challenges? Is rehabilitation a special case in evidence-based health care approaches? What challenges have I encountered in doing evidence-based rehabilitation? What are possible ways and answers?
4 What is the background to the present challenges?
5 background era of assessment and accountability, revolution of medical care (Relman 1988 NEJM) Need for quality assurance and scientific foundation of health care Clear-cut orientation towards consequences of care: independent of reasons and motives for professional decisions, does the intervention do more good than harm? core question of ebm Relman AS (1988) Assessment and accountability. The third revolution in medical care. New Engl J Med 319:
6 background Theoretical reasoning, plausibilty or personal experience is insufficient to legitimate interventions Consequence: research evidence for practice is needed Clincial study as the ideal of evidence base in research practice (cf. Chan et al. 2014) Chan L, Heinemann AW, Roberts J. Elevating the quality of disability and rehabilitation research: mandatory use of the reporting guidelines. Arch Phys Med Rehabil Mar;95(3): doi: /j.apmr
7 Is rehabilitation a special case in evidence-based health care approaches?
8 One side of the coin: No special case Need to legitimize what we are doing with patients in rehab care We have to know if what we do in rehab does more good than harm (and to what degree) Problem of unwarranted variation present in rehab, as in other health care fields Strong causal claims of interventions need a randomized-controlled study design
9 The turning side of the coin: Yes, it is a special case There are characteristics of rehab that interfere with a simple evaluative framework Problems of rehab embedded in social law framework ( right for rehab ) Effectiveness of services is also dependent on context factors, such as the quality of the therapists (person-, not just intervention related) the quality of interdisciplinary team work overarching concept organisation of care
10 What challenges have I encountered in doing evidencebased rehabilitation?
11 Rehab as a special case Functional, multidimensional outcomes Outcomes are always personal to some degree Multidisiplinary approaches by definition Complexity of the intervention ( black box ) Complexity of context of intervention ( double complexity ) Rehab success is to a high degree dependent on factors not in direct control of rehab professionals Unwarranted rehab service variation
12 Meyer (2010) Medizinische Rehabilitation für Menschen mit chronischen Rückenschmerzen: Variation des Erfolgs zwischen Rehabilitanden und Rehabilitationskliniken. Habilitationsschrift, Medizinische Fakultät der Universität zu Lübeck. 100% 90% 80% Variation of rehab-interventions variance of duration of services accounted for by rehab centers independent of patient characteristics intra-class correlation coefficient (ICC) 80,7% 80.7% 76,2% 76.2% 70% 64,7% 64.7% 60% 50% 40% 53,7% 53.7% 57,1% 57.1% 51,4% 51.4% 38,6% 38.6% 30% 27,0% 27.0% 26,9% 26.9% 24,1% 24.1% 20% 10% 0% ETM01 phyiscal exercise ETM02 ETM03 ETM04 ETM05 ETM06 ETM07 ETM08a ETM08b ETM08c back pain relaxation & motiv- couns. & therapy couns. re-inte- manange information psychol. occup. social vocational after-care school manage ment excercise ation therapy gration ment ETM = evidencebased treatment module
13 Rehab as a special case Essential to distinguish among studies that address single interventions can give guidance for professionals which interventions to choose; causal conclusions useful studies that relate to whole complex of rehab phases can legitimize the whole integrated approach and is in essence patient-centrered studies that relate to local evidence of single institutions can help patients which rehab service to choose and commissioners in managing the rehab system
14 What are possible ways and answers?
15 Knowledge translation Central question: What kinds of evidence reliably support predictions of effectiveness for health and social care interventions? Cartwright N, Munro E (2010) The limitations of randomized controlled trials in predicting effectiveness. Journal of Evaluation in Clinical Practice 16:
16 Knowledge translation: learning from philosophy of sciences Evidence-based policy. Your are told: use politics that work. And you are told: RCTs randomized controlled trials will show you what these are. That s not so. RCTs are great, but they do not do that for you. What they tell you is true that this policy produced that result there. But they do not tell you why this is relevant to what you need to bet on getting the result you want here. For that, you will need to know a lot more. (ix) Introduction of the concept of (stable) capacities (causal power) Cartwright N, Hardie J (2012) Evidence-based policy. A practical guide for doing it better. Oxford: OUP.
17 Knowledge translation: learning from qualitative research Three models of generalization in empirical research statistical generalization analytic generalization transferability Polit DF, Beck CT (2010) Generalization in quantitative and qualitative research: Myths and strategies. International Journal of Nursing Studies 47:
18 Knowledge translation: learning from qualitative research Transferability case-to-case translation, reader generalizability collaborative effort between researcher and reader responsibiltiy of the researcher: provide detailed or thick descriptions, including the context task of the reader: evaluate the extent to which the findings apply ones own (or other) situations proximal similarity, i.e. a gradient of similarity for times, people, settings, and contexts Polit DF, Beck CT (2010) Generalization in quantitative and qualitative research: Myths and strategies. International Journal of Nursing Studies 47:
19 Knowledge translation: learning from health services research The perspective of health services research efficacy-study: provides evidence that an intervention is effective under optimal conditions contextual factors are held constant effectiveness-study: provides evidence that an intervention is effective in real life conditions contextual factors are seen to provide as error variance health services research: provides evidence on which conditions the interventions do more good than harm contextual factors as the variables of interest
20 Resumée the field of rehabilitation needs more sophisticated answers to which evidence is needed for practice different solutions have to be acknowledged and adapted to rehab problems there is a way forward: join Cochrane Rehab
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