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1 Journal title Alimentary Pharmacology and Therapeutics American Journal of Clinical Nutrition Anesthesia and analgesia Ann Emerg Med Annals of Allergy, Asthma and Immulogy Archives of disease in childhood Archives of facial plastic surgery : Archives of neurology Augmentative and alternative communication Australian and New Zealand Journal of Medicine Australian journal of primary health BMC cancer BMC clinical pharmacology BMC pulmonary medicine Cancer Cardiovascular therapeutics Circulation Journal Clinical gastroenterology and hepatology : Clinics (São Paulo, Brazil) Croatian medical journal Current Therapeutic Research - Clinical and Experimental Dental traumatology : Diabetology and Metabolic Syndrome Diagstic pathology Foot (Edinburgh, Scotland) Gait & posture Gynecological Endocrilogy Hepatology Human Reproduction Hypertension in Pregnancy Indian Journal of Medical Research International journal of methods in psychiatric research International Journal of Neuropsychopharmacology International journal of pediatric otorhilaryngology Journal of clinical rheumatology Journal of Dual Diagsis Journal of Experimental and Clinical Cancer Research Journal of Hand Surgery Journal of pediatric gastroenterology and nutrition Journal of prosthodontic research Journal of Reproduction & Infertility Liver international : Multidisciplinary Respiratory Medicine Nature medicine Nutrition, metabolism, and cardiovascular diseases : NMCD Open Diabetes Journal Open Respir Med J Pediatric endocrilogy, diabetes, and metabolism Pediatric research Reproductive Biology and Endocrilogy Rheumatology Requires registration? Requires Helsinki? Helsinki date

2 Thorax Thyroid : official journal of the American Thyroid Association World Journal of Biological Psychiatry World journal of surgical oncology Abdominal imaging 1964 Acta dermatovenerologica Alpina, Panica, et Adriatica Acta Medica Croatica Actas dermo-sifiliográficas Advances in therapy Alzheimer disease and associated disorders American Academy of Optometry (Opt & Vision Science) American Journal of Gastroenterology American journal of industrial medicine Andrologia Annals of tropical medicine and parasitology 2000 Anti-cancer drugs latest ANZJFT Australian and New Zealand Journal of Family Therapy Appetite 1964 Applied Ergomics Archives of the Balkan Medical Union Archives of women's mental health 1964 Archivos de bronconeumología Arhiv za higijenu rada i toksikologiju ASAIO journal (American Society for Artificial Internal Organs : 1992) Assistive techlogy : the official journal of RESNA Audiology & Neurotology British journal of haematology Canadian journal of public health. Canadian Journal of Urology Cancer gene therapy Child maltreatment Children and Youth Services Review Chinese journal of cancer Chinese journal of traumatology = Zhonghua chuang shang za zhi Chinese-German Journal of Clinical Oncology Cleft Palate-Craniofacial Journal Clin Exp Otorhilaryngol Clinical chemistry 2008 Clinical orthopaedics and related research 1964 Current Hypertension Reports 1964 Cytotherapy? Der Internist Developmental psychology Diabetes and Vascular Disease Research? 1989 Endocrine Epidemiology (Cambridge, Mass.) link European archives of paediatric dentistry : European Eating Disorders Review European journal of cancer prevention : latest

3 European journal of drug metabolism and pharmacokinetics European journal of epidemiology latest European Journal of General Medicine European journal of medical genetics European journal of radiology? link Explore: The Journal of Science and Healing 1975 Eye & contact lens Gerodontology Health psychology : Hellenic journal of nuclear medicine 1964 Infant Mental Health Journal Infection Control and Hospital Epidemiology Intellectual and developmental disabilities International Journal of Diabetes in Developing Countries International journal of environmental research and public health International nursing review 2008 Iranian Journal of Pharmaceutical Research 2008 Journal of atherosclerosis and thrombosis 1983 Journal of athletic training 1990 Journal of behavioral medicine Journal of cancer survivorship : research and practice Journal of chromatographic science Journal of clinical and experimental hematopathology : JCEH Journal of Clinical Child and Adolescent Psychology Journal of Clinical Rehabilitative Tissue Engineering Research Journal of Clinical Sleep Medicine Journal of Consulting & Clinical Psychology Journal of dentistry for children (Chicago, Ill.) Journal of health services research & policy Journal of intellectual & developmental disability Journal of Medical and Biological Engineering 2004 Journal of neuro-ophthalmology : Journal of neuropathology and experimental neurology Journal of neurophysiology Journal of nuclear medicine techlogy Journal of pediatric ophthalmology and strabismus Journal of periodontology 2000 Journal of personality Journal of proteome research Journal of psychoactive drugs Journal of religion and health Journal of the American Academy of Audiology Journal of the American Dietetic Association Journal of the Medical Association of Thailand Journal of Thoracic Oncology Journal of thrombosis and thrombolysis Journal of urban health Journal of vestibular research : equilibrium & orientation Kathmandu University Medical Journal Life sciences link

4 Magnesium research : Manuelle Therapie Mediterranean Journal of Nutrition and Metabolism 1964 Minerva medica Natural product communications Neurocritical care Neurologia i neurochirurgia polska 1989 Neurological sciences : Nursing research Oncology reports Ostomy Wound Management Otolaryngol Head Neck Surg Pharmaceutical research 1964 Psychology and aging Psychopharmacology 1964 Public health reports (Washington, D.C. : 1974) Pulmonary Pharmacology & Therapeutics. link QJM : monthly journal of the Association of Physicians Revista de saúde pública Safety Science SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance / SAHARA, Human Sciences Scandinavian journal of clinical and laboratory investigation 1983 Scandinavian journal of immulogy Schizophrenia research link Skinmed Social psychiatry and psychiatric epidemiology Surgical invation The journal of the Turkish Society of Algology The South African journal of communication disorders. Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings The Tohoku journal of experimental medicine Therapeutics and Clinical Risk Management Thoracic and Cardiovascular Surgeon Trakya Universitesi Tip Fakultesi Dergisi 2002 Transfusion Transplant immulogy Transplantation proceedings 1983 Tsitologiia Tüberküloz ve toraks link Türk Kardiyoloji Dernei arivi yayn organr Tzu Chi Medical Journal U.S. Army Medical Department journal 2008 Ultrasound in medicine & biology link Urologia Vox sanguinis Western Journal of Nursing Research Women's health issues : official publication of the Jacobs 2000 Institute of Women's Health Wounds: A Compendium of Clinical Research & Practice Clinical drug investigation encourages Dev Med Child Neurol encourages Journal of neurosurgical anesthesiology encourages

5 Table: Journals included in the quantitative analysis sorted by requirements for trial registration and (for those that did t require registration) whether they stated that clinical trials must comply with the Declaration of Helsinki (and the version cited).

Requires registration? Helsinki?

Requires registration? Helsinki? Journal title Requires registration? Requires Helsinki? Helsinki date Abdominal imaging 1964 Acta dermatovenerologica Alpina, Panica, et Adriatica Acta Medica Croatica Actas dermo-sifiliográficas Advances

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