SBRT IN THE MANAGEMENT OF PROSTATE CANCER SATELLITE SYMPOSIUM AT THE AMERICAN SOCIETY FOR RADIATION ONCOLOGY (ASTRO) 2018 ANNUAL MEETING ADVANCES IN

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1 DEPARTMENT OF RADIATION ONCOLOGY ADVANCES IN SBRT IN THE MANAGEMENT OF PROSTATE CANCER SATELLITE SYMPOSIUM AT THE AMERICAN SOCIETY FOR RADIATION ONCOLOGY (ASTRO) 2018 ANNUAL MEETING OCTOBER 21, 2018 MARRIOTT RIVERWALK IN ALAMO BALLROOM C San Antonio, Texas Accredited by for 2.75 CME Credits

2 OVERVIEW Stereotactic Body Radiation Therapy (SBRT) has emerged as an exciting and validated treatment option for men with localized prostate cancer. This program will be supported by the unique radiobiology of prostatic adenocarcinoma coupled with innovations in treatment delivery. Long-term data continues to emerge demonstrating favorable biochemical control with low normal tissue toxicity. This symposium will be designed to provide physicians with an overview of the long-term data, as well as to explore the clinical questions that remain regarding optimizing the sure of SBRT for cure while minimizing side effects. To promote understanding of the intricacies of SBRT, an internally renowned group of clinician scientists will be assembled to lead this discussion. LEARNING OBJECTIVES At the end of this conference, participants should be able to: Describe the radiobiologic and physics-related rationale for employing stereotactic body radiation therapy for prostate cancer Analyze appropriate candidates for prostate SBRT as well as expected outcomes related to biochemical control and toxicity Integrate holistic approaches with conventional management of localized disease Summarize controversies and future directions regarding SBRT for prostate cancer, including sequencing with more conventional therapies and changes in prescribed dose to tumor and normal tissue. Explain future direction of SBRT for use in prostate cancer treatment TARGET AUDIENCES: Radiation Oncologists Urologists Medical Oncologists Primary Care Physicians Medical Physicists General Surgeons COMPETENCIES: This symposium will address the following ACGME/ABMS competencies: Patient Care Medical Knowledge Systems-based practice IOM Aims for Care (Safe, Timely, Effective, Efficient, Equitable & Patient Centered Care) ACCREDITATION ACCME ACCREDITATION is Accredited With Commendation by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians through 3/31/2019. Provider #: AMA CREDIT DESIGNATION designates this live activity for a maximum of 2.75 AMA PRA Category 1 Credit(s). Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Society for Radiation Oncology (ASTRO) has reviewed and approved this symposium as appropriate for presentation as an Industry Satellite Symposium. The symposium constitutes the content and views of the provider and is not part of the official ASTRO Annual Meeting program.

3 AGENDA 6:15p Light Dinner Buffet 6:30p Introduction and Welcome Jonathan Haas, MD 6:35p Rationale and Radiobiology of SBRT: Comparing Treatment Platforms Jonathan Haas, MD 6:50p The History of SBRT for Prostate Cancer: The Experience Seth Blacksburg, MD, MBA 7:10p 5-7 Year Outcomes from a Prospective Multi-Institutional Trial: Homogenous Dose Distribution Robert M. Meier, MD 7:30p Challenging Cases Utilizing SBRT for Prostate Cancer: The MSKCC Experience Michael Zelefsky, MD 7:50p Break 8:00p SBRT: The Urologists Perspective Aaron E. Katz, MD, FACS 8:20p SBRT as a Salvage Option for Localized Recurrent Disease Donald B. Fuller, MD 8:40p KEYNOTE ADDRESS State of the Science: Dose Escalation in SABR for Prostate Cancer Robert D. Timmerman, MD 9:00p Panel Discussion Q & A Jonathan Haas, MD and Seth Blacksburg, MD, MBA

4 FACULTY Jonathan Haas, MD * (Activity Director) Chair, Department of Radiation Oncology Associate Professor of Clinical Medicine Stony Brook University School of Medicine Stony Brook, NY Seth Blacksburg, MD, MBA * (Activity Co-Director) Associate Director, Radiation Oncology Medical Director, NYCyberknife Mineola, NY Robert D. Timmerman, MD Effie Marie Cain Distinguished Chair in Cancer Therapy Research Professor of Radiation Oncology and Neurological Surgery UT Southwestern Medical Center Dallas, TX Michael Zelefsky, MD Vice Chair, Department of Radiation Oncology, Clinical Research; Chief, Brachytherapy Service Memorial Sloan Kettering Cancer Center New York, NY Donald B. Fuller, MD Radiation Oncologist Genesis Healthcare Partners, Inc. CyberKnife Centers of San Diego, Inc. San Diego, CA Aaron E. Katz, MD, FACS Chair, Department of Urology Professor of Urology Stony Brook University School of Medicine Mineola, NY Robert M. Meier, MD Medical Director of Radiation Oncology Radiosurgery Center Swedish Medical Center Seattle, WA PLANNING COMMITTEE MEMBER Awais Mirza Administrative Manager, Radiation Oncology NYCyberknife New York, NY FACULTY DISCLOSURE It is the policy of to adhere to ACCME, NEMSD and ANCC accreditation requirements, policies and Standards for Commercial Support in order to ensure content validity, fair balance, independence, objectivity and scientific rigor in all its sponsored programs. All faculty, planners and authors of educational content, who participate in sponsored programs, must disclose to the audience any potential, apparent or real conflicts of interest related to their contribution to the activity, as well as any discussions of off-label or investigational uses of any commercial products or devices not yet approved in the United States. All faculty disclosures will be made at the time of the activity. *Planning Committee Member

5 REGISTRATION We accept online registration ONLY for all NYU Winthrop CME-CE courses. Please register for FREE at SPACE IS LIMITED. REGISTER EARLY. All registrants will receive a confirmation via . If you do not receive an after registering, please Keyana Golds at Keyana.Golds@ nyulangone.org ACCOMMODATIONS We do not have a discounted room block for this meeting. However, if you require a hotel room, we suggest that you contact the Marriott Riverwalk Hotel by calling (210) MORE INFORMATION If you experience technical problems with the online system, wish to register a group or require other special arrangements, please contact Keyana Golds at (516) or via at Keyana.Golds@nyulangone.org for assistance.

6 ADVANCES IN SBRT IN THE MANAGEMENT OF PROSTATE CANCER SATELLITE SYMPOSIUM AT THE AMERICAN SOCIETY FOR RADIATION ONCOLOGY (ASTRO) 2018 ANNUAL MEETING OCTOBER 21, 2018 Register Online All rights reserved CME Office Publications x Design & Production: Station Plaza North, Suite 510 Mineola, NY Non Profit Org US Postage Paid Permit #13 Mineola, NY