Youngbin Kwak, Ph.D.

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1 Youngbin Kwak, Ph.D. Contact Information Academic Position Education Publications Center for Cognitive Neuroscience B355, Levine Science Research Center, Duke University Durham, NC Phone: Postdoctoral Associate, Sep 2011-present Center for Cognitive Neuroscience Duke University Advisor: Scott A. Huettel University of Michigan Ph.D. in Neuroscience, Aug 2011 Dissertation title: From Gene to Brain and Behavior: Dopaminergic Effects on Motor Sequence Learning in Parkinson s Disease (Chair: Rachael Seidler, Ph.D.) Seoul National University (Seoul, Korea) M.S. in Neuroscience, 2006 Seoul National University (Seoul, Korea) B.A. in International Relations, 2004 Kwak, Y., Bohnen, N.I., Muller, M. L.T.M., Dayalu, P., Burke, D.T., Seidler, R.D. (under review). Task-dependent interactions between Dopamine D2 receptor polymorphisms and L-DOPA in patients with Parkinson's disease. (2012). L-DOPA changes spontaneous low-frequency BOLD signal oscillations in Parkinson s disease: a resting state fmri study. Frontiers in Systems Neuroscience. 6:52. Kwak, Y., Muller, M. L.T.M., Bohnen, N.I., Dayalu, P., Seidler, R.D. (2012). L- DOPA impairs ventral striatum recruitment during motor sequence learning in Parkinson s disease. Behavioral Brain Research. 230(1): Fling B.W., Kwak, Y., Peltier, S.J., Seidler, R.D. (2011). Differential relationships between transcallosal structural and functional connectivity in young and older adults. Neurobiology of Aging. (2010). Altered cortico-striatal functional connectivity in mild to moderate stage Parkinson s disease. Frontiers in Systems Neuroscience. 4:143. Kwak, Y., Muller, M. L.T.M., Bohnen, N.I., Dayalu, P., Seidler, R.D. (2010). Effect of Dopaminergic Medications over the Time Course of Explicit Motor

2 Sequence Learning in Parkinson s Disease. Journal of Neurophysiology. 103(2): * Awarded the first place in BCBSM 2010 Excellence in Research Award for Students. * Selected to be highlighted in a press release to the AP by University of Michigan, School of Kinesiology, and highlighted in Michael J. Fox foundation. (Manuscripts in preparation) Kwak, Y., Pearson, J., Huettel, S.A. (in preparation). Earning for oneself and earning for others: Differential learning of reward for self and others predicts pro-social behavior. Kwak, Y., Bohnen, N.I., Muller, M. L.T.M., Dayalu, P., Seidler, R.D. (in preparation). Individual differences in nigrostriatal dopaminergic denervation correlate with L-DOPA effects on motor sequence learning in Parkinson s disease. Bo, J., Lee, C.M., Kwak, Y., Peltier, S.J., Bernard, J.A., Buschkuehl, M., Jaeggi, S.M., Wiggins, J.L., Jonides, J., Monk, C.S., Seidler, R.D. (in prepration). Lifespan Changes in Cortico-striatal Resting State Connectivity. Bernard, J.A., Peltier, S.J., Benson, B.L., Wiggins, J.L., Jaeggi, S.M., Buschkuehl, M., Fling, B.W., Kwak, Y., Jonides, J., Monk, C.S., Seidler, R.D. (in prepration). Disrupted cortico-cerebellar connectivity in older adults. Sottile M., Kwak, Y., Miller N.S, Bohnen, N.I., Muller, M. L.T.M., Dayalu, P., Seidler, R.D. (in preparation). Polymorphisms in COMT and DRD2 genes modulate L-DOPA response to motor timing performance in Parkinson s Disease. Miller, N.S., Kwak, Y., Bohnen, N.I., Muller, M. L.T.M., Dayalu, P., Seidler, R.D. (in preparation). The pattern of striatal dopaminergic denervation explains motor timing performance in Parkinson s disease. (Book Chapters and Reviews) Seidler, R.D., Kwak, Y., Fling, B.W., Bernard, J.A. (2012) Neurocognitive mechanisms of error-based motor learning. Invited paper for a proceedings book based on the 2011 Progress in Motor Control conference. Seidler, R.D., Benson, B.L., Boyden, N.B., Kwak, Y. (in press). Skill learning. In K.N. Ochsner & S.M. Kosslyn (Eds.), Oxford Handbook of Cognitive Neuroscience. New York: Oxford University Press. Seidler, R.D., Bernard, J.A., Burutolu, T.B., Fling, B.W., Gordon, M.T., Gwin, J.T., Kwak, Y., and Lipps, D.B. (2010). Motor Control and Aging: Links to Age-Related Brain Structural, Functional, and Biochemical Effects. Neuroscience and Biobehavioral Reviews. 34(5): Awards and Scholarships Margaret Ayers Host Award, Rackham Graduate School, University of Michigan, 2011 Blue Cross Blue Shield of Michigan (BCBSM) foundation Student Award,

3 First place, BCBSM foundation Excellence in Research Award for Students, 2010 Rackham Travel Grant, University of Michigan, 2008, 2010 Fine Science Tools Travel Award, Neuroscience Program, University of Michigan, 2009 Rackham Graduate Student Research Grant, University of Michigan, 2007, 2009 University scholarship, Seoul National University, Summer Travel Grant for Training Abroad, Seoul National University, 2005 Conference Presentations F. Noohi, N.B. Boyden, Y. Kwak, J. Humfleet, D.T. Burke, M.L.T.M. Muller, N.I. Bohnen, R.D. Seidler. Effect of COMT val158met DRD2 c-6277-t Genotype on age-related motor decline. 19th Annual Cognitive Neuroscience Society, Mar 31-Apr3, N. Miller, Y. Kwak, M. Sottile, M.L.T.M. Muller, N.I. Bohnen, J. Bo, P. Dayalu, R.D. Seidler. Is rhythmic synchronization impaired in Parkinson s disease? 19th Annual Cognitive Neuroscience Society, Mar 31-Apr3, C.M. Lee, J. Bo, Y. Kwak, S.J. Peltier, J. Bernard, M. Buschkuehl, S. Jaeggi, J.L. Wiggins, J. Jonides, C. Monk, R.D. Seidler. Lifespan Changes in Corticostriatal Resting State Connectivity. Society for Neuroscience 41st Annual Meeting, Nov , Miller, N. S., Kwak, Y., Muller, M. L. T. M., Bohnen, N., Dayalu, P., & Seidler, R. D. Striatal dopaminergic denervation in Parkinson s disease is correlated with motor timing impairments. Society for Neuroscience 41st Annual Meeting, Nov , Kwak, Y., Muller, M. L.T.M., Bohnen, N.I., Dayalu, P., Seidler, R.D. Neural mechanisms of dopaminergic effects on motor sequence learning in Parkinson s disease: an fmri and DTBZ PET study, 18th Annual Cognitive Neuroscience Society, April 2-5, Changes in the amplitude of low-frequency oscillations in Parkinson s disease: a resting state fmri study, Society for Neuroscience 40th Annual Meeting, Nov , Boyden. N.B., Kwak, Y., Humfleet, J., Bohnen, N.I., Muller, M. L.T.M., Burke, D.T., Seidler, R.D. Individual differences in sensorimotor performance and motor sequence learning, Society for Neuroscience 40th Annual Meeting, Nov , Altered cortico-striatal functional connectivity in Parkinson s disease, Altered cortico-striatal functional connectivity in Parkinson s disease, International Conference on Resting-State Functional Brain Connectivity, in Sep , Altered cortico-striatal functional connectivity in Parkinson s disease,

4 Organization for Human Brain Mapping s 16th Annual Meeting, in June 6-10, Kwak, Y., Muller, M. L.T.M., Bohnen, N.I., Dayalu, P., Seidler, R.D. Dopaminergic effects on brain activation during motor sequence learning in Parkinson s disease, Society for Neuroscience 39th Annual Meeting, Oct , Kwak, Y., Muller, M. L.T.M., Bohnen, N.I., Dayalu, P., Huismann, D.J., Seidler, R.D. Impaired Early Learning of Explicit Motor Sequences by Dopaminergic Medications in Parkinsons Disease, Society for Neuroscience 38th Annual Meeting, Nov , Kwak, Y., Muller, M. L.T.M., Bohnen, N.I., Dayalu, P., Huismann, D.J., Seidler, R.D. Impaired Early Learning of Explicit Motor Sequences by Dopaminergic Medications in Parkinsons Disease, 12th International Congress of Parkinson s Disease and Movement Disorders, June, 22-26, S. Lee, Y. Kwak, J. Chey, The Range of Basal Cortisol Associated with Decreased Glucose Metabolism in the Temporal Lobe and Lower Declarative Memory Performance, Society for Neuroscience 35th Annual Meeting, Nov , S. Cho, Y. Kwak, E. Lee, J. Chey, S. Kim, Metabolic Correlates of General Cognitive Function in Nondemented Elderly Subjects: An FDG PET Study, The 11th Annual Meeting of the Organization For Human Brain Mapping, June 12-16, Y. Kwak, S. Cho, S. Lee, J. Chey, S. Kim, Relationship between Salivary Cortisol Levels and Regional Cerebral Glucose Metabolism in Nondemented Elderly Subjects, The 7th Annual Meeting of the Korean Society for Brain and Neural Sciences, Dec. 1, Y. Kwak, S. Cho, E. Lee, Y. Kim, W. Lee, J. Chey, S. Kim, Different Neural Correlates of Spatial Working Memory between High and Low Performing Elderly Subjects: An FDG PET Study, 52nd Annual Meeting of the Society of Nuclear Medicine, June 18-23, *Nominated for the Young Investigator s Award. Y. Kwak, S. Cho, S. Lee, Y. Kim, W. Lee, J. Chey, S. Kim, Relationship between Salivary Cortisol Levels and Regional Cerebral Glucose Metabolism in Nondemented Elderly Subjects, 52nd Annual Meeting of the Society of Nuclear Medicine, June 18-23, Invited Talks Department of Bio & Brain Engineering, Korea Advanced Institute of Science and Technology, Sep, 2012 Korea Research Institutes of Standards and Science, Sep, 2012 Center for Cognitive Neuroscience, Duke University. Feb, 2011 Gabrieli Lab, MIT. Jan, 2011 Boston Children s Hospital, Jan, 2011 University of Michigan Fall 2010 fmri Symposium. Title: Altered cortico-striatal

5 functional connectivity in mild to moderate stage Parkinson s disease. Sep, 2010 Mental Health & Well-Being Translational Approaches for Basic Psychological Research Distinguished Faculty/Graduate Student seminar series. Title: Altered Resting State Cortico-Striatal Connectivity in Parkinson s Disease. Mar, 2010 Ann Arbor Parkinson s disease support group. Title: Motor skill learning in Parkinson s disease. Dec, 2007 Teaching Graduate Student Instructor for MVS 320 Laboratory for Motor Control, Fall 2009 Graduate Student Instructor for Psych 240 Intro to Cognitive Psychology, Winter 2008 Service Activities Mentored a number of undergraduate research: Jamie Stark, Evan Sheets (Duke University, ), Melanie Sottile, Matthew Vallevand (University of Michigan, ) Neuroscience graduate program recruitment weekend, 2007 Membership Member since Jan, 2010, Organization for Human Brain Mapping Member since Feb, 2008, Cognitive Neuroscience Society Member since May, 2006, Society for Neuroscience Skills and Languages References Matlab, E-Prime, PsychToolbox, SPM, FSL, SPSS Fluent in both spoken and written English, Native in Korean Scott Huettel, Ph.D. (scott.huettel@duke.edu), Duke University, Department of Psychology and Neuroscience, Center for Cognitive Neuroscience Rachael D. Seidler, Ph.D. (rseidler@umich.edu), University of Michigan, Department of Psychology, School of Kinesiology, and Neuroscience Program Nicolaas I. Bohnen, M.D., Ph.D. (nbohnen@umich.edu), University of Michigan, Departments of Neurology and Radiology Martijn L.T.M. Muller, Ph.D. (mtmuller@umich.edu), University of Michigan, Department of Radiology J. Wayne Aldridge, Ph.D. (jwaynea@umich.edu), University of Michigan, Department of Psychology and Neuroscience Program Thad A. Polk, Ph.D. (tpolk@umich.edu), University of Michigan, Department of Psychology and Neuroscience Program

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