CURRICULUM VITAE CHERIE MARVEL, PhD December, 2011

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CURRICULUM VITAE CHERIE MARVEL, PhD December, 2011 DEMOGRAPHIC & PERSONAL INFORMATION Current Appointment: Assistant Professor Primary: Department of Neurology, Division of Cognitive Neuroscience

1 CURRICULUM VITAE CHERIE MARVEL, PhD December, 2011 DEMOGRAPHIC & PERSONAL INFORMATION Current Appointment: Assistant Professor Primary: Department of Neurology, Division of Cognitive Neuroscience Joint: Department of Psychiatry & Behavioral Sciences The Johns Hopkins University School of Medicine Personal Data: Johns Hopkins University School of Medicine Neurology, Division of Cognitive Neuroscience 1620 McElderry Street, Reed Hall 2E, Rm Baltimore, MD Phone: (410) Fax: (410) Web: EDUCATION & TRAINING (in chronological order): BS Tufts University Biopsychology PhD Georgetown University Neuroscience Post-doctoral Fellowship University of Iowa Clinical Neuroscience Post-doctoral Fellowship Johns Hopkins University Cognitive Neuroscience PROFESSIONAL EXPERIENCE Dates Positions Institutions Laboratory Technician Depts. of Biology & Psychology, Georgia State University, Atlanta, GA Research Assistant Dept. of Psychiatry, Veterans Affairs Medical Center, Washington, DC Postdoctoral Fellow Dept. of Psychiatry, University of Iowa, Iowa City, IA Spring 2005 Adjunct Assistant Professor Dept. of Psychology, University of Iowa, Iowa City, IA Postdoctoral Fellow Dept. of Neurology, Johns Hopkins University, Baltimore, MD Research Associate Dept. of Neurology, Johns Hopkins University, Baltimore, MD Assistant Professor Dept. of Neurology; Psychiatry & Behavioral Sciences Johns Hopkins University, Baltimore, MD RESEARCH ACTIVITIES

2 Peer-Reviewed Publications (in chronological order): * Indicates corresponding author 1. Mintz, E. M.; Gillespie, C. F.; Marvel, C. L.; Huhman, K. L.; Albers, H. E. Serotonergic regulation of circadian rhythms in Syrian hamsters. Neuroscience. 1996; 79: Huhman, K. L.; Gillespie, C. F.; Marvel, C. L.; Albers, H. E. Neuropeptide Y phase shifts circadian rhythms via Y 2 -like receptors. NeuroReport. 1996; 7: Gillespie, C. F.; Mintz, E. M.; Marvel, C. L.; Huhman, K. L.; Albers, H. E. GABA A and GABA B agonists and antagonists alter the phase-shifting effects of light when microinjected into the suprachiasmatic region. Brain Research. 1996; 759: Huhman, K. L.; Gillespie, C. F.; Marvel, C. L.; Albers, H. E. Peptidergic mechanisms of action in the suprachiasmatic nucleus. Annals of the New York Academy of Science. 1996; 814: Huhman, K. L.; Marvel, C. L.; Gillespie, C. F.; Mintz, E. M.; Albers, H. E. Tetrodotoxin blocks NPY- but not muscimol-induced phase shifts of activity rhythms. Brain Research. 1997; 772: Mintz, E.M.; Marvel, C.L.; Gillespie, C.F.; Price, K.M.; Albers, H.E. Activation of NMDA receptors in the suprachiasmatic nucleus produces light-like phase shifts of the circadian clock in vivo. Journal of Neuroscience. 1999; 19(12): Drapalski, A.L.; Rosse, R.B.; Peebles, R.R.; Schwartz, B.L.; Marvel, C.L.; Deutsch, S.I. Topiramate improved deficit symptoms in a patient with schizophrenia when added to his stable regimen of antipsychotic medication. Clinical Neuropharmacology. 2001; 24(5): Schwartz, B.L.; Marvel, C.L.; Drapalski, A.L.; Rosse, R.; Deutsch, S.I. The role of configural information in face recognition in schizophrenia. Cognitive Neuropsychiatry. 2002; 7(1): Deutsch, S.I., Schwartz, B.L., Rosse, R.B., Mastropaolo, J., Marvel, C.L., Drapalski, A.L. Adjuvant topiramate administration: A pharmacological strategy for addressing NMDA receptor hypofunction in schizophrenia. Clinical Neuropharmacology. 2003; 26(4): * Marvel, C.L., Schwartz, B.L., Isaacs, K.L. Word production deficits in schizophrenia. Brain & Language. 2004; 89(1): * Marvel, C.L., Schwartz, B.L., Rosse, R.B. A quantitative measure of postural sway deficits in schizophrenia. Schizophrenia Research. 2004; 68(2-3): * Marvel, C.L., Schwartz, B.L., Howard, D.V., Howard, J.H. Implicit learning of non-spatial sequences in schizophrenia. Journal of the International Neuropsychological Society. 2005; 11(6): Turner, B.M.A.; Paradiso, S; Marvel, C.L.; Pierson, R.; Ponto L.L.B.; Hichwa, R.D.; Robinson, R.G. The cerebellum and emotional experience. Neuropsychologia. 2007; 45,(6): * Marvel, C.L.; Turner, B.M.; O Leary, D.S.; Johnson, H.J.; Pierson, R.K.; Boles Ponto, L.L.; Andreasen, N.C. The neural correlates of implicit sequence learning in schizophrenia. Neuropsychology. 2007; 21(6): * Marvel, C.L. and Desmond, J.E. The Contributions of Cerebro-Cerebellar Circuitry to Executive Verbal Working Memory, Cortex. 2010; 46(7): * Marvel, C.L. and Desmond, J.E. Functional Topography of the Cerebellum in Verbal Working Memory, Neuropsychology Review. 2010; 20: * Marvel, C.L. and Desmond, J.E. From Storage to Manipulation: How the Neural Correlates of Verbal Working Memory Reflect Varying Demands on Inner Speech, Brain & Language, in press. 18. *Marvel, C.L.; Faulkner, M.L.; Strain, E.C.; Mintzer, M.Z.; Desmond, J.E. An fmri Investigation of Cerebellar Function During Verbal Working Memory in Methadone Maintenance Patients, The Cerebellum, in press. Page 2 of 7

3 Inventions, Patents, Copyrights (pending, awarded) Extramural Funding (current, pending, previous) CURRENT Dates: 09/30/ /29/2015 Title: Cerebro-Cerebellar Contributions to Cognitive Function in Drug Addiction ID#: 1K01 DA Sponsor: NIH/NIDA Total Direct Cost: $805,559 Role: PI, 100% Major Goals: The goal of the proposed project is to identify neural mechanisms that contribute to executive dysfunction in drug addiction and, at the same time, enable the applicant to establish an independent research career in the study of drug addiction. PREVIOUS FUNDING Dates: 8/1/2005-7/31/2011 Title: fmri and TMS Analysis of Cerebellar Cognitive Function ID#: R01MH60234 Sponsor: NIH/NIMH Annual Direct Cost: $991,732 Principal Investigator: John Desmond Role: Post-Doctoral Trainee/Investigator, 100% effort 10/01/ /14/2009; 60% effort 12/15/ /29/2010 Major Goals: The goal of this project is to elucidate the role of the cerebellum in cognitive function by combining event-related functional magnetic resonance imaging and transcranial magnetic stimulation with tasks of human verbal working memory. Dates: 07/01/ /31/2014 Title: Biomarkers of Cognitive Decline Among Normal Individuals: The BIOCARD Cohort ID#: U01 AG Sponsor: NIH/NIA & NIMH Annual Direct Cost: $7,451,081 Principal Investigator: Marilyn Albert Role: Senior Level Research Associate, 40% effort 12/15/ /29/2010 Major Goals: The major goals of the proposal are to: (1) Identify biomarkers that are associated with progression from normal cognitive status to mild cognitive impairment (MCI) or dementia, with a particular focus on the dementia of Alzheimer's disease (AD); (2) Determine which cross-sectional or longitudinal biomarker measures (taken alone or in combination) are the best predictors of progression from normal cognition to varying levels of cognitive dysfunction (i.e., MCI or AD); (3) Create a publicly accessible data base containing the clinical, cognitive, imaging, blood and CSF data. Dates: Title: Assessing the Specificity of Neuropsychiatric Symptoms Associated with Drug Abuse: Identifying a Drug-Induced Form of Schizophrenia ID#: None Sponsor: Nellie Ball Trust Research Fund Total Direct Cost: $20,000 Role: PI Major Goals: This proposal focuses on illicit drug abuse in schizophrenia and addresses the possibility that these drugs are not being used by patients as a form of self-medication but instead serve as a precipitating factor for developing schizophrenia. Page 3 of 7

4 Dates: Title: A Novel Quantification of Motor Deficits and Brain Morphology in Schizophrenia and Well First- Degree Relatives: Identifying a Potential Marker of Genetic Vulnerability ID#: None Sponsor: Nellie Ball Trust Research Fund Total Direct Cost: $21,670 Role: PI Major Goals: This project examined the etiology of fundamental motor deficits (e.g., unsteady posture) in schizophrenia by using quantitative measures of balance and brain structure in never-medicated patients with schizophrenia and their first-degree relatives. Dates: Title: Research Training: Major Psychoses/Clinical Neurobiology ID#: T32 MH19113 Sponsor: NIH/NIMH Total Direct Cost: $865,000 Principle Investigator: Nancy C. Andreasen Role: Post-doctoral Trainee, 100% Major Goals: This is a multidisciplinary program, particularly designed to train young investigators in clinical neuroscience areas relevant to the study of major psychoses. Dates: Title: "Implicit Learning of Covariation in Schizophrenia ID#: F31 MH12207 Sponsor: NIH/NIMH Total Direct Cost: $45,146 Role: PI/Pre-doctoral Trainee, 100% Major Goals: Schizophrenia patients have difficulty interpreting facial emotions. This proposal examines their ability to implicitly learn facial stimuli. Findings may demonstrate an intact system for learning covariations in internal facial features could lead to a therapeutic means for teaching schizophrenia patients how to interpret social cues. EDUCATIONAL ACTIVITIES Educational Publications (In Chronological Order): Peer-Reviewed Publications See publications: #4 and #16. Invited Reviews 1. *Marvel, C.L. and Paradiso, S. Cognitive and neurological impairment in mood disorders. Psychiatric Clinics of North America. 2004; 27(1): *Marvel, C.L. Schizophrenia and language. In Keith Brown, Editor-in-Chief, Encyclopedia of Language and Linguistics, 2 nd ed. 2006; Vol. 11, Oxford: Elsevier, Desmond, J.E. and Marvel, C.L. Cognition: Cerebellum Role. In Larry R. Squire, Editor-in- Chief, Encyclopedia of Neuroscience. 2009; Vol.2, Oxford: Academic Press, Teaching Classroom Instruction: 2005 spring Abnormal Psychology for Allied Health Professionals, Adjunct Assistant Professor, University of Iowa, Department of Psychology, Iowa City, IA. Page 4 of 7

5 Page 5 of Introduction to Neuroscience ("Neuronal Plasticity", "Psychopathology of Schizophrenia ), Guest Lecturer, Georgetown University, Department of Biology, Washington, DC Disorders and Diseases of the Brain ("Neurobiology of Depression", "Neurobiology of Schizophrenia"), Guest Lecturer and Co-Founder, Georgetown University, Department of Cognitive Science, Washington, DC Neuroscience Seminar Series ( Research in Cognition in Schizophrenia ), Guest Lecturer, Georgetown University, Department of Neuroscience, Washington, DC Cognitive Psychology ("Cognition in Schizophrenia"), Guest Lecturer, Catholic University of America, Department of Psychology, Washington, DC Cognitive Psychology ("Cognition in Schizophrenia"), Guest Lecturer, Georgetown University, Department of Psychology, Washington, DC Principles of Nervous System Organization and Function (Neuroanatomy), Graduate Teaching Assistant, Georgetown University, Interdisciplinary Program in Neuroscience, Washington, DC Statistics in Psychology, Undergraduate Teaching Assistant, Tufts University, Department of Psychology, Medford, MA. Workshops/Seminars: Dec , 2011 Network Analysis: Functional Connectivity, a workshop on the use SPM8 to analyze fmri data for functional connectivity patterns in the brain, taught by Tom Zeffiro, MD, PhD (Neurometrika), co-organized with Jacinda Dariotis, PhD (JHSPH), held at Johns Hopkins University, Baltimore, MD. Nov , 2011 Methods for Studying Human Cerebellar Structure and Function, Satellite Symposium of the Society for Neuroscience, co-organized with Tom Zeffiro, MD, PhD, held at Johns Hopkins University, Baltimore, MD. Mar 14-18, 2011 SPM for Basic and Clinical Investigators, a workshop on the use SPM8 for image processing and data analysis, taught by Tom Zeffiro, MD, PhD, co-organized with Jacinda Dariotis, held at Johns Hopkins University, Baltimore, MD. Jan. 19, 2011 Grant Writing: K Awards, presented at the Johns Hopkins Neurology Faculty Development Retreat, Baltimore, MD. July 14, 2005 Improved Spatial Localization of PET Activations Using Non-Linear Warping Co- Registration Methods, presented at University of Iowa Brains Camp, Iowa City, IA. Oct. 12, 2004 Cognitive Deficits in Schizophrenia, presented at the Iowa Association of Community Providers 2004 Mental Health Conference, Ames, IA. July 16, 2003 Correlating Brain Physiology with Behavior, presented at the University of Iowa Brains Camp, Iowa City, IA. Mentoring Trainees: Diana Liao, Research Assistant, undergraduate at Johns Hopkins, assists with research data collection and analyses in fmri and TMS studies of working memory Monica Faulkner, MA, Study Coordinator, assists with recruitment, data collection, and data analysis of fmri studies of working memory in healthy and patient populations Jonathan Cooper, BA, Research Assistant, Johns Hopkins University, currently a Research Coordinator at Memorial Hospital of Rhode Island Diane Echavarria, BA, Research Assistant, Johns Hopkins University, currently a Research Program Coordinator at Johns Hopkins School of Medicine Preeti Kumar, MD, Research Assistant University of Iowa Travis Jewitt, OD, Graduate Research Assistant, Neuroscience program at the University of Iowa, currently owns his own chiropractic practice Grant Goldsberry, MD, Radiologist, Graduate Research Assistant as a Doris Duke Fellow, University of Iowa, currently a practicing Radiologist Educational Program Building/Leadership

6 Educational Extramural Funding CLINICAL ACTIVITIES ORGANIZATIONAL ACTIVITIES Institutional Administrative Appointments Chair, Dept. of Neurology Internal K/R Grant Review Committee Institutional Center for Translational Research (ICTR) Review Committee, ad-hoc member Editorial Activities Ad-Hoc Journal Peer Review Acta Neuropsychiatrica American Journal of Psychiatry Behavioural Neurology Biological Psychiatry Brain Connectivity Cerebellum Cerebral Cortex Experimental Brain Research Human Brain Mapping Journal of Affective Disorders Journal of Neurology Journal of Neurophysiology Journal of Neuroscience Journal of the International Neuropsychological Society Neurobiology of Aging Neuroimage Neuropsychologia Neuropsychology Psychiatry Research Psychopharmacology Schizophrenia Bulletin Book proposal review: Wiley Publishers Professional Societies 1996-present Society for Neuroscience, Member 1998-present Cognitive Neuroscience Society, Member 2004-present Organization for Human Brain Mapping, Member, Conference Abstract Reviewer 2010-present Greater Baltimore Chapter Association for Women in Science, Member 2011-present International Society of Behavioral Neuroscience, Member RECOGNITION Awards & Honors Emerging Women s Leadership Program, Office of Women in Science and Medicine, Johns Hopkins University School of Medicine Young Investigator Award, International Congress on Schizophrenia Research, Savannah, GA Travel Grant Awardee (x3), Georgetown University Medical Center s Graduate Student Organization, Washington, DC Graduated cum laude, Tufts University, Medford, MA Valedictorian, Smyrna High School, Smyrna, DE. Invited Talks Sept 8, 2011 June 5, 2011 Surprising Interactions Between the Motor System and Cognitive Processing, Department of Neurology Grand Rounds, Johns Hopkins University School of Medicine, Baltimore, MD. The Neural Correlates of Verbal Working Memory During High vs. Low Manipulation Demands: An fmri Investigation of Healthy and Drug-Addicted Populations, presented to the International Society of Behavioral Neuroscience, Verona, Italy. Page 6 of 7

7 May 9, 2011 Oct. 28, 2010 Feb. 22, 2010 Mar. 21, 2006 Dec. 10, 2004 Feb. 3, 2002 The Role of Cerebro-Cerebellar Circuits in Verbal Working Memory presented to the Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD. The Role of Cerebro-Cerebellar Circuits in Verbal Working Memory presented to the Department of Psychology, Catholic University of America, Washington, DC. Cerebro-Cerebellar Contributions to Executive Function presented to the Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD. The Role of the Cerebellum in Schizophrenia, presented to the Interdisciplinary Program in Neuroscience, Georgetown University, Washington, DC. The Role of the Cerebellum in Cognitive and Motor Deficits in Schizophrenia, presented to the Department of Psychology, Tufts University, December 10, 2004, Medford, MA. Implicit Sequence Learning in Schizophrenia, presented to the Department of Psychiatry, University of Iowa Hospitals & Clinics, Iowa City, IA. Page 7 of 7

Samantha K. Holden, MD East 17th Avenue Campus Box B185 Aurora, CO Phone:

Samantha K. Holden, MD East 17th Avenue Campus Box B185 Aurora, CO Phone: EDUCATION Samantha K. Holden, MD University of Colorado Anschutz Medical Campus, Colorado Clinical and Translational Sciences Institute, Clinical Sciences Graduate Program, M.S. in Clinical Science. Expected