ITI. INNOVATIVE THERAPIES based on IMMUNOLOGY. July 1-3, 2013 Cordeliers Research Center Paris, France PRELIMINARY PROGRAMME

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1 Lorem Ipsum ITI INNOVATIVE THERAPIES based on IMMUNOLOGY 20 Fello wships availab le! & CME cre dits! July 1-3, 2013 Cordeliers Research Center Paris, France PRELIMINARY PROGRAMME This course is organized by: In partnership with: This course has been scientifically endorsed by: Info & Contact :

2 Lorem Ipsum 2 Goal & benefits of the summer school Benefits of the summer school 2,5 days of intensive learning at the forefront of immunotherapies Network with top speakers in an informal atmosphere Target participants Early Career Scientists Phd, Post-docs & Early Career MDs Topics & Technics covered Cancer Autoimmunity Allergy Rheumatology Diabetes Multiple sclerosis Gastroenterology Dermatology Immunodeficiencies Genetics Micro arrays Micro RNA Prognostics markers Antibody therapies Vaccines Gene transfer Personalized medecine 20 Hours or education & Up to 10 CME Credits Up to 10 ECMEC accredited by the European Accreditation Council for Continuing Medical Education (EACCME). More Info : Strong networking with top experts We bring you close to the experts during very interactive sessions: 2 lunches with speakers Meet the expert session, where participants can present and discuss their results and get career advices with the speakers of their choice. 20 Fellowships available! The EFIS grants 20 free registrations to participants early in their careers. Guidelines: Applicants must be under 35 years of age, affiliated to an academic or public institution and must be a member of an EFISaffiliated society. Go to the EFIS webpage to see if your society is a member of EFIS or write to A summer school directed by: Pr. Catherine Sautès-Fridman EFIS Past President Director, Department of Immunology, Cancer & Inflammation Cordeliers Research Center, Paris, France. Pr. Wolf-Hervé Fridman, MD. Director, Cordeliers Research Center Cordeliers Research Center, Paris, France Pr. Steffen Gay, MD. EULAR representative Director, Center of Experimental Rheumatology Department of Rheumatology, University Hospital, Zurich, Switzerland

3 Lorem Ipsum 3 Top speakers at the forefront of immunotherapies Prof. Burkhard Becher, Institute of Experimental Immunology, Department of Neuroimmunology, University of Zurich, Switzerland. Prof. Wolf-Hervé Fridman, Director of the Cordeliers Research Center, Paris, France. - Petit d Ormoy Prize from the French Academy of Sciences Institut de France. - International Prize «William B. Coley Award» from the Cancer Research Institute, for the major contribution in the discovery of the immune response against cancer (2010). Prof. Steffen Gay, Director of the Center of Experimental Rheumatology, University Hospital Zurich, Switzerland. - Kussmaul-Medal from the German Society of Rheumatology. Prof. Lars Klareskog, Chairman of the Rheumatology Clinic and Rheumatology Research Unit, Karolinska Institute, Sweden. - Member of the Nobel Assembly at the Karolinska Institute. - The Dutch Rheumatology Society International Prize for Rheumatology research Jaan van Bremer medal ; Hasinger prize of the German Rheumatism Center, and the Wyeth Rheumatology Prize. Prof. Guido Kroemer, Director of the Metabolomics facility of the Institut Gustave Roussy, France. - Descartes Prize of the European Union, the Carus Medal of the German Academy of Sciences, the Grand Prix Mergier-Bourdeix of the French Academy of Sciences. Prof. Xavier Mariette, Head of the Rheumatology Department of Bicetre Hospital, Paris, France. Prof.Winfried Pickl, Head of Division of cellular Immunology and Immuno-Hematology, Medical University of Vienna, Austria. Prof. Fiona Powrie, Head of the Experimental Medicine Division at the John Radcliffe Hospital, University of Oxford, UK. - Winner of the 2009 Ita-Askonas Prize for an outstanding woman career Louis-Jeantet Prize for medicine. Prof. Gerhard Rogler, Division of Gastroenterology and Hepatology, Department of Internal Medicine, University-Hospital of Zürich, Switzerland. Prof. Maria Grazia Roncarolo, Scientific Director of the San Raffaele Scientific Institute, Milan, Italy. - Member of the European Academy of Sciences. - Ufficiale dell Ordine Al Merito della Repubblica Italiana for scientific merits. Prof. Catherine Sautès-Fridman, Head of Immunology, Cancer and Inflammation Department, Cordeliers Research Center, Paris, France. - Behring Metchnikoff Prize, Prix Petit d Ormoy Prize from the French Academy of Sciences. Prof. Alexander K. So, Department of Medicine, University Hospital, Lausanne, Switzerland. Prof. George Stingl, Head of Faculty in Dermatology/DIAD, Vienna General Hospital, Austria. - William Montagna Award and the Stephen Rothman Award from the Society for Investigative Dermatology (SID). Prof. Rudolf Valenta, Head of the Division of Immunopathology, Medical University of Vienna, Austria. - International Award from the Pharmacia Allergy Research Foundation, Sarstedt Award. Prof. Cornelius Verweij, Head of the section of Inflammatory Disease Profiling at the VU University medical center (VUmc) in Amsterdam, Netherlands. Prof. Klaus Warnatz, Center of Chronic Immunodeficiency, University Medical Center, Freiburg, Germany.

4 Lorem Ipsum 4 General Information Dates & venue Ü July 1-3 rd Ü Centre de Recherche des Cordeliers, in the heart of Paris, in a scientific & medical campus and public research university: Centre de Recherche des Cordeliers 15, rue de l Ecole de Médecine Paris Google Map link: Access by bus: lines 38, 27, 58 stops: Rue des Ecoles or Odeon by metro: lines 4, 10 stop: Odeon RER B, RER C stop: Saint Michel Fellowships Registration Registrations will open on Feb. 1 st Registration fees include: - Participation to all the course sessions - Course documents: printed programme including speaker s abstracts at the conference and speakers slide presentations after the conference - Lunch on July 2 nd and 3 rd. - Coffee breaks - Social Hour with Wine and Cheese - Name badge FEES On-line registration before May 15, 2013 On-line registration after May 15, 2013 Academic* Non Academic* Hotel booking A list of hotels from different categories will be available at the opening of the registration on Feb. 1 st The EFIS grants 20 free registrations to participants early in their careers. Guidelines: Applicants must be under 35 years of age, affiliated to an academic or public institution and must be a member of an EFIS-affiliated society. Go to the EFIS webpage to see if your society is a member of EFIS or write to Application deadline: May 3 rd 2013 For more Info, please write to

5 Lorem Ipsum 5 Preliminary Programme Background Inflammation is an expanding public health problem as it intervenes in diverse chronic diseases (IBD, RA, chronic respiratory disease, atherosclerosis, asthma ) as well as in cancer and transplantation. Progress in the treatment of these immune mediated inflammatory disorders depends upon the successful applications of immunology to clinical medicine. Innovative strategies for immunotherapy for cancer, autoimmune diseases, transplantations have been developed. An increasing number of clinicians is using immunotherapeutic approaches or protocols and particularly for chronic diseases with immunological features (ie Chronic inflammatory disease, Transplantation, oncology). The immune system also plays a key role in the rejection of transplanted organs, and in defense against invading cancer cells. Moreover the relatively new field of regenerative medicine relies upon tolerance of the immune system to stem cells. There is therefore a clear need for a regular update in immunology and innovative therapies based on the immune system for practitioners and biomedical scientists. We invite you to participate in this high level course on the principles and practice of innovative immunology-based therapies. More Info :

6 Lorem Ipsum 6 Preliminary Programme Monday, July 1 st Ü 14:00-14:55 New Insights into the Immune System: "The light and dark sides of the Force Catherine Sautès-Fridman (France) Ü 15:00-15:55 Genetics and environmental factors for RA Lars Klareskog (Sweden) Ü 16:00-16:55 MicroRNAs in RA: potential roles in diagnosis and therapy Steffen Gay (Switzerland) Keynote Lecture Ü 17:30-18:30 From Intestinal inflammation to cancer, role of the innate lymphoid cells Fiona Powrie (UK) Social Hour with Wine & Cheese Ü 17:30-18:30 Tuesday, July 2 nd Ü 8:30-9:25 Immunity and novel immunotherapies in cancer Wolf-Hervé Fridman (France) Ü 9:30-10:30 Immunogenic chemotherapies Guido Kroemer (France) Ü 11:00-11:55 Physiopathology & treatment of immunodeficiencies Klaus Warnatz (Germany) Lunch with speakers Ü 12:00-13:45 Ü 13:45-14:40 Engineered allergen-specific immunotherapy vaccines, from bench to bedside Rudolf Valenta (Austria) Ü 14:45-15:40 Modulation of allergen-specific immune responses: Novel concepts, tools and platforms Winfried Pickl (Austria) Ü 16:10-17:05 Modeling multiple sclerosis in laboratory animals Burkhard Becher (Switzerland) Meet the Experts Sessions Ü 17:10-19:00 Smaller sessions where participants present and discuss their results and career to speakers of their choice. Wednesday, July 3 rd Ü 8:30-9:25 Novel drugs in development for dermatology Georg Stingl (Austria) Ü 9:30-10:30 The inflammasome a target for therapy in diseases Alexander K So (Switzerland) Ü 11:00-11:55 New targets in gastroenterology Gerhard Rogler (Switzerland) Lunch with speakers Ü 12:00-13:45 Ü 13:45-14:40 Novel therapeutic strategies in RA Xavier Mariette (France) Ü 14:45-15:40 The interferon signature towards personalized medicine Cornelius Verweij (Netherlands) Ü 15:45-16:40 Diabetes: Lessons and perspectives More Info :