LIVER CANCER: FROM BENCH TO CLINIC

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1 Mount Sinai Liver Cancer Program Icahn Medical Institute Icahn School of Medicine at Mount Sinai Goldwurm Auditorium 1425 Madison Avenue at 98th Street New York, NY Program Director JOSEP M. LLOVET, MD Professor of Medicine Director, Mount Sinai Liver Cancer Program Sponsored by Mount Sinai Liver Cancer Program The Icahn School of Medicine at Mount Sinai

2 Location Icahn Medical Institute Goldwurm Auditorium 1425 Madison Avenue at 98th Street New York, NY Icahn School of Medicine at Mount Sinai Faculty Program Director JOSEP M. LLOVET, MD, Professor of Medicine Director, Mount Sinai Liver Cancer Program Program Chairs SCOTT L. FRIEDMAN, MD, Professor of Medicine, Dean for Therapeutic Discovery MYRON SCHWARTZ, MD, Professor of Surgery, Director of Liver Surgery SAMUEL WAXMAN, MD, Professor of Medicine, Department of Hematology and Medical Oncology, Department of Oncological Sciences Activity Description This conference will assemble multidisciplinary experts on liver cancer from the Mount Sinai Liver Cancer Program and 2 outstanding invited lecturers. The meeting is intended to provide a summary of the state-of-the-art knowledge of the pathogenesis and clinical management of liver cancer, and the research conducted in Mount Sinai. Activity Learning Objectives Assess and classify the basic molecular alterations in HCC and cholangiocarcinoma Review the impact of novel anti-viral therapies in development of HCC Describe the current management of HCC and novel prospects Evaluate novel therapies to be approved in liver cancer Registration Fee Complimentary Register Online Target Audience Hepatologists and Gastroenterologist, Oncologists, Surgeons, Radiologist, Pathologists and Basic Scientists interested in liver cancer from the New York Area. Accreditation The Icahn School of Medicine at Mount Sinai is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Credit Designation The Icahn School of Medicine at Mount Sinai designates this live activity for a maximum of 6.5 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity. Verification of Attendance Verification of attendance will be provided to all professionals. Special Needs The Icahn School of Medicine at Mount Sinai is in full compliance with provisions of the Americans with Disabilities Act (ADA) and is accessible for individuals with special needs. If you require special accommodations please contact the Page and William Black Post- Graduate School of Medicine at Acknowledgment Supported by education grants from: Bayer HealthCare, Blueprint Medicines, BTG International, Gilead Sciences

3 FRIDAY, DECEMBER 18, 2015 PROGRAM 8:30 9:00am Registration 9:00 9:10am Welcome and Opening Steven Burakoff, MD Director, Tisch Cancer Institute 9:10 9:40am Achievements of Mount Sinai Liver Cancer Program Josep M. Llovet, MD 9:40 10:15am Hans Popper Lecture: Introduction: Scott L. Friedman, MD 10:15 10:30am Coffee Break New Experimental Models for Liver Cancer Scott W. Lowe, PhD Memorial Sloan Kettering Cancer Center, New York, NY PREVENTION AND SURGICAL THERAPIES OF HCC Chairman: Myron Schwartz, MD, Mount Sinai Liver Cancer Program, Department of Surgery 10:30 10:50am Overview of HCV Treatments and Outcomes Ira Jacobson, MD Site Chair, Department of Medicine Mount Sinai Beth Israel 10:50 11:10am Impact of Novel Antiviral Therapies in the Development of HCC Ponni Perumalswami, MD Division of Liver Diseases 11:10 11:30am Pathological Markers that Define Primary Liver Cancers M. Isabel Fiel, MD Mount Sinai Liver Cancer Program, Department of Pathology 11:30 11:50am Surgical Management of HCC: New Trends Myron Schwartz, MD Mount Sinai Liver Cancer Program, Department of Surgery 11:50 12:30pm Lunch Mount Sinai Liver Cancer Program 2 nd Annual NYC Pain Symposium

4 MANAGEMENT OF INTERMEDIATE/ ADVANCED Chairman: Josep M. Llovet, MD, Mount Sinai Liver Cancer Program, Division of Liver Diseases 12:30 12:50pm Management and Indications of TACE and TARE Edward Kim, MD Mount Sinai Liver Cancer Program, Department of Radiology 12:50 1:10pm Overview of Novel Agents in Phase II and Phase III- Opportunities in HCC Josep M. Llovet, MD 1:10 1:30pm Assessing Response with mrecist after TACE and Systemic Therapies Bachir Taouli, MD Mount Sinai Liver Cancer Program, Department of Radiology 1:30 1:50pm Overview of Management of Advanced ICC Celina Ang, MD Mount Sinai Liver Cancer Program, Division of Hematology and Medical Oncology 2:00 2:20pm Coffee Break 2:20 3:00pm State-of-the-art Lecture: Introduction: Samuel Waxman, MD Department of Hematology and Medical Oncology Department of Oncological Sciences Exploring Origins of Cholangiocarcinoma with GEMM Supriya K. Saha, MD, PhD Massachusetts General Hospital, Boston, MA NOVEL DRIVERS OF HEPATOCARCINOGENESIS Chairman: Scott L. Friedman, MD, Mount Sinai Liver Cancer Program, Division of Liver Diseases 3:00 3:20pm Discovery of Novel Targets for Treating Intrahepatic CC Daniela Sia, PhD 3:20 3:40pm Overview of Drivers, and How to Discover Novel Targets in HCC Amaia Lujambio, PhD Mount Sinai Liver Cancer Program, Department of Oncological Sciences 3:40 4:00pm Liquid Biopsy in Liver Cancer: Clinical Implications Augusto Villanueva, MD, PhD 4:00 4:20pm Molecular Signatures in HCC: Clinical Translation Yujin Hoshida, MD, PhD 4:20 4:40pm Linking Fibrosis, Autophagy and HCC Youngmin Lee, MD, PhD 4:40 pm Closing Remarks

5 Mount Sinai Liver Cancer Program LAST NAME FIRST NAME Degree ADDRESS CITY STATE ZIP TELEPHONE INSTITUTION/AFFILIATION Confirmation will be sent via Registration Fee: Complimentary Register Online at: Cancellation Policy: All cancellations must be ed to no later than December 7, Conference Information Office of CME at

6 Icahn School of Medicine at Mount Sinai The Page and William Black Post Graduate School One Gustave L. Levy Place, Box 1193 New York, NY MOUNT SINAI LIVER CANCER PROGRAM Icahn Medical Institute Icahn School of Medicine at Mount Sinai Goldwurm Auditorium Complimentary Registration Online:

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