Arnold and Mabel Beckman Center of the National Academies of Sciences and Engineering. 100 Academy Way, Irvine, CA 92617

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2 LOCATION PROGRAM 7:30 am REGISTRATION & CONTINENTAL BREAKFAST 8:00 am Welcome 8:10 am Introductory Remarks Ralph V. Clayman, MD Dean, UC Irvine School of Medicine Ischemic Stroke and TIA 8:20 am Pre-Hospital Treatment of Stroke Jeffrey L. Saver, MD 8:55 am Evaluation and Diagnosis of Acute Ischemic Stroke 9:20 am Acute Stroke Imaging Anton N. Hasso, MD 9:45 am Current Status of IV tpa Treatment for Acute Ischemic Stroke Patrick D. Lyden, MD 10:20 am MORNING BREAK 10:35 am Neuro-Endovascular Treatment of Acute Ischemic Stroke Fong Y. Tsai, MD Arnold and Mabel Beckman Center of the National Academies of Sciences and Engineering 100 Academy Way, Irvine, CA DIRECTIONS From the Los Angeles Area Follow Interstate 405 south to Highway 73 South/SJH Toll Road. Follow Highway 73 approximately 2 miles and exit at University Drive. Turn left on University Drive and continue to California Avenue. Turn right on California Avenue, then turn right at the first street, Academy. From the San Diego Area Follow Interstate 5 north to Interstate 405 north. Take the Jeffrey/University Drive off ramp and turn left. Continue on University Drive approximately 3 miles to California Avenue. Turn left on California Avenue, then right at the first street, Academy. From the Riverside Area Take the 91 Freeway west to the 55 Freeway south to Interstate 405 south. Exit at Jamboree Road west toward the coast. Continue on Jamboree Road to Campus Drive. Turn left at Campus Drive. Continue on Campus Drive to University Drive. Turn right on University Drive to the second signal, California Avenue. Turn left on California Avenue, then turn right at the first street, Academy. Carotid and Cardiac Causes of Acute Ischemic Stroke: Diagnosis and Management 11:00 am Cardiac Causes of Ischemic Stroke Jagat Narula, MD 11:25 am Carotid Stenosis and Ischemic Stroke Roy M. Fujitani, MD Noon LUNCH Stroke Prevention 1:00 pm Secondary Stroke Prevention Mark J. Fisher, MD Brain Hemorrhage 1:35 pm Intracranial Hemorrhage: Diagnosis and Treatment Lama M. Al-Khoury, MD 2:00 pm Treatment of Subarachnoid Hemorrhage Steven L. Giannotta, MD 2:35 pm AFTERNOON BREAK 2:50 pm Neuro-Endovascular Management of Cerebral Aneurysms Shuichi Suzuki, MD After the Stroke: Stroke Rehabilitation 3:15 pm Brain Recovery/Repair After Stroke Steven C. Cramer, MD Stroke Systems of Care 3:50 pm Creating and Maintaining a Countywide Pre-Hospital Stroke System Samuel J. Stratton, MD 4:25 pm Organizing a Joint Commission-Certified Primary Stroke Center Dana Stradling, RN 4:45 pm SUMMATION & ADJOURN

3 FACULTY COURSE DIRECTOR Assistant Clinical Professor Director, UC Irvine Stroke & Cerebrovascular Center University of California, Irvine GUEST FACULTY Steven L. Giannotta, MD Chairman & Professor Department of Neurological Surgery Keck School of Medicine of USC Patrick D. Lyden, MD Chair, Cedars-Sinai Medical Center Carmen and Louis Warshaw Endowed Chair of Neurology Cedars-Sinai Medical Center Los Angeles, CA Jeffrey L. Saver, MD Professor of Neurology Medical Director, UCLA Stroke Center UCLA Medical Center David Geffen School of Medicine at UCLA Los Angeles, CA Samuel J. Stratton, MD Medical Director Orange County Emergency Medical Services UNIVERSITY OF CALIFORNIA, IRVINE FACULTY Lama M. Al-Khoury, MD Assistant Clinical Professor Anton N. Hasso, MD Professor, Director, Neuroimaging Research Department of Radiological Sciences Ralph V. Clayman, MD Professor Dean, School of Medicine Jagat Narula, MD Professor Chief, Division of Cardiology Department of Medicine Steven C. Cramer, MD Associate Professor Dana Stradling, RN, BSN, CNRN Program Manager UC Irvine Stroke & Cerebrovascular Center Mark J. Fisher, MD Professor Shuichi Suzuki, MD Associate Professor Department of Radiological Sciences Roy M. Fujitani, MD Professor of Clinical Surgery Chief, Division of Vascular & Endovascular Surgery Department of Surgery Fong Y. Tsai, MD Professor of Clinical Radiology Department of Radiological Sciences

4 CME LEARNING OBJECTIVES 0 Discuss current and emerging treatment options for stroke and other cerebrovascular diseases to improve patient outcomes. 0 Identify appropriate imaging techniques in the management of acute stroke and cerebrovascular diease to enable more efficient and effective treatment. 0 Apply the current evidenced-based pharmacologic and lifestyle strategies for stroke prevention. 0 Appreciate the role of rehabilitation in optimizing post-stroke recovery. ACCREDITATION STATEMENT The University of California, Irvine School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. DESIGNATION STATEMENT The University of California, Irvine School of Medicine designates the educational activity for a maximum of AMA PRA Category 1 Credits. Physicians should only claim credit commensurate with the extent of their participation in the activity. ADA STATEMENT In compliance with the Americans with Disabilities Act, we will make every reasonable effort to accommodate your needs. For any special requests, please contact Laurie Gumser at AB1195 This activity is in compliance with California Assembly Bill 1195 which requires continuing medical education activities with patient care components to include curriculum in the subjects of cultural and linguistic competency. For specific information regarding Bill 1195 and definitions of cultural and linguistic competency, please visit the CME website at DISCLOSURE STATEMENT It is the policy for the University of California, Irvine School of Medicine and University of California CME Consortium to ensure balance, independence, objectivity and scientific rigor in all CME activities. Full disclosure of conflict resolution will be made in writing via handout materials or syllabus.

5 REGISTRATION 2010 Stroke & Cerebrovascular Disease Management & Emerging Therapies Saturday, October 30, 2010 ARNOLD AND MABEL BECKMAN CENTER OF THE NATIONAL ACADEMIES OF SCIENCES AND ENGINEERING CONTACT INFORMATION NAME (First, Middle, Last) CREDENTIALS ORGANIZATION MEDICAL SPECIALTY Preferred mailing address is (select one): m Work/Business m Home ADDRESS CITY STATE ZIP (required for confirmation) TELEPHONE m Cell m Home m Work FAX Special Needs: If you have special assistance needs or dietary restrictions, please describe here: REGISTRATION Symposium Registration Fee: m Physicians $50 m PA s/nurses/allied Health Professionals $25 PAYMENT INFORMATION m Check is enclosed in the amount shown at right make checks payable to UC REGENTS $ Credit Card (select one): ACCOUNT NUMBER EXP. DATE m MC m Visa (MO/YR) m AmEx m Discover SIGNATURE DATE PLEASE MAIL OR FAX COMPLETED REGISTRATION FORM AND CHECK TO: UC Irvine Medical Center Laurie Gumser, Business Development 333 City Blvd West, Suite 1205, Orange, CA (fax) lgumser@uci.edu

6 333 City Blvd West, Suite 1205 Orange, CA Presorted FIRST CLASS MAIL US Postage P A I D Santa Ana, CA Permit #1106 COURSE OVERVIEW This multidisciplinary symposium will address current concepts in pathology, radiology, surgery, management, clinical outcomes, basic science and experimental therapy related to stroke and cerebrovascular diseases, including pharmacologic and lifestyle changes. Presentations will be made by invited nationally recognized experts in stroke, as well as by expert University of California, Irvine faculty from the departments of Neurology, Neurological Surgery, Emergency Medicine, Radiology and Physical Medicine & Rehabilitation. TARGET AUDIENCE Neurologists, neurosurgeons, neurointerventional radiologists, radiologists, neurointensivists, physiatrists, primary care physicians, internal medicine physicians, family medicine physicians, emergency medicine physicians, nurses, nurse practitioners, physician assistants, paramedics, emergency medicine technologists, speech therapists, physical therapists, occupational therapists, and other healthcare professionals who wish to update their knowledge of the management of patients with stroke and select cerebrovascular diseases.