TUESDAY, MARCH 28, 2017 WEDNESDAY, MARCH 29, 2017 WELCOME RECEPTION (VIENNA CITY HALL)

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1 KEY: PRE CONFERENCE SYMPOSIUM SPONSORED SYMPOSIUM SYMPOSIUM PLENARY LECTURE FORUM OTHER EVENT *PRE-REGISTRATION IS REQUIRED FOR THE INFORMAL NETWORKING WITH PROFESSOR LUNCH SESSION TUESDAY, MARCH 28, :00-17:00 PRE CONFERENCE SYMPOSIUM -COMMON FEATURES OF NEURODEGENERATIVE DISEASES: EXPLORING THE BRAIN-EYE CONNECTION AND BEYOND (08:30-17:30) PRE CONFERENCE SYMPOSIUM - IMAGING SATELLITE (08:30-16:30) PRE CONFERENCE SYMPOSIUM -NEUROPATHOLOGY WORKSHOP WEDNESDAY, MARCH 29, :30-10:30 THE ALZHEIMER S DISEASE SEQUENCING PROJECT DISEASE MECHANISMS CHARACTERIZATION OF EARLY DISEASE STAGE APP PROCESSING, ABETA AND BACE1 TRANSLATIONAL STRATEGIES 1 10:30-11:00 11:00 13:00 PROPAGATION OF TAU-PATHOLOGY TREATMENT STRATEGIES FOR PD, DLB AND MSA IMAGING AND BIOMARKERS 1 CELLULAR AND ANIMAL MODELS 1 TRANSLATIONAL STRATEGIES 2 13:00 14:00 14:00 16:00 AD/PD 2017 ALZHEIMER ANIMAL MODEL FORUM: PREDICTIVE TRANSLATION - MICE, DOGS, NON-HUMAN PRIMATES AND HUMANS? SEEDING, SPREADING, AND PROTEIN AGGREGATION MECHANISMS UPDATE ON PD ETIOLOGY AND MANIFESTATIONS MITOCHONDRIA, ER AND OXIDATIVE STRESS 16:00 16:20 16:20-16:35 ADPD 2017 IN MEMORIUM 16:35 17:05 OPENING CEREMONY AND AWARDS 17:05-17:35 GENE SILENCING THERAPY FOR HUMAN NEURODEGENERATIVE DISEASE 17:35-18:05 CELL-TO-CELL TRANSMISSION OF NEURODEGENERATIVE DISEASE PROTEINS 19:30 WELCOME RECEPTION (VIENNA CITY HALL)

2 THURSDAY, MARCH 30, :30-09:00 APOE, SYNAPSES, AND ALZHEIMER S DISEASE 09:15-11:15 APOE: MECHANISMS AND APOE-BASED TREATMENT STRATEGIES CAA, VASCULAR AND WHITE MATTER AMYLOID PRODUCTION AND ABETA TOXICITY NEURONAL NETWORKS, SYNAPTIC FUNCTION AND DYSFUNCTION 11:45-13:30 13:30-14:45 AD/PDTM 2017 FORUM ON TRANSLATIONAL RESEARCH IN DRUG DISCOVERY FOR AD: A PLETHORA OF TARGETS - WHICH IS THE BEST, IS THERE A BEST ONE? BIOMARKERS 2: AD CLINICAL AND PATHOLOGICAL ASPECTS OF AD, PD AND DLB ALPHA-SYNUCLEIN DISEASE MECHANISMS TAU RELATED MECHANISMS TAUOPATHIES 1 17:15-19:15 SYNAPTIC AND CHOLINERGIC DEFICITS, Ca2+. ER STRESS, SIGMA-1 RECEPTORS, GPCRS ANIMAL MODELS (2) - NEW WAYS TO GO? BIOMARKERS AND DIAGNOSTICS TOOLS 19:15-19:25 19:25-21:25

3 FRIDAY, MARCH 31, :30-09:00 CURRENT DEVELOPMENTS IN THE TREATMENT OF PARKINSON S DISEASE FROM DISEASE MODIFICATION TO PREVENTION? 09:15-11:15 AMYLOID-REDUCING THERAPIES IN ALZHEIMER S DISEASE MRI POTENTIAL NOVEL BIOMARKERS IN AD, PD, LBD, MCI TRANSLATIONAL STRATEGEIS 3 11:45-13:25 13:25-14:45 AD/PDTM 2017 FORUM ON NOVEL APPROACHES TO DISEASE-MODIFYING THERAPIES OF PD: THERAPY OF PD BEYOND NEUROTRANSMITTER REPLACEMENT. CAN WE STOP PROGRESSION? GENETICS OF AD, ALS AND FTD TAU PET IMAGING MICROBIOME AND NUTRITION DISEASE MECHANISMS IN CELLULAR AND ANIMAL MODELS 17:15-19:15 GENETICS 2: EPIGENETIC AND GENETIC MECHANISMS AMYLOID PET BACE AND GAMMA SECRETASES :00 CONFERENCE EDUCATIONAL LECTURE

4 SATURDAY, APRIL 1, :30-09:00 STAGING PATHOLOGY WITH PET 09:15-11:15 IMMUNE MECHANISMS, GLIA AND INFLAMMATION GENETICS OF PD AND DLB AUTOPHAGY CEREBRAL AMYLOID ANGIOPATHY, HUNTINGTON'S, TTR-RELATED AMYLOIDOSIS, AND OTHER NEURODEGENERATIVE DISEASES 11:45-13:25 MODELING NEURODEGENERATIVE DISEASE IN NEURON CULTURE SYSTEMS 13:25-14:45 AD/PDTM 2017 ALZHEIMER CLINICAL PHASE 3 FORUM: THE RACE FOR THE FIRST DISEASE MODIFYING DRUG FOR AD: FACTORS FOR SUCCESS TAU TARGETING STRATEGIES AND TOOLS NEURONAL DEGENERATIONS IN PD PINK1, LRRK AND PARKIN GENETICS, TRANSCRIPTOMICS AND EPIDEMIOLOGY 17:15-19:15 TREM2 TDP 43 AND C9ORF72 STEM CELLS

5 SUNDAY, APRIL 2, :30-09:00 BLOOD BRAIN BARRIER DYSFUNCTION, NEURODEGENERATION AND ALZHEIMER S DISEASE 09:15-11:15 VASCULAR ASPECTS OF NEURODEGENERATION ALPHA-SYNUCLEIN: PATHOLOGICAL MECHANISMS THERAPEUTIC STRATEGIES IN AD CASPASES AND OTHER PROTEASES TAU BIOLOGY AND DISEASE MECHANISMS COFFEE 11:45-13:45 DISSECTING THE MECHANISTIC CONNECTION BETWEEN LYSOSOMAL DISEASES AND PD DISEASE MECHANISMS LATE ING THERAPEUTIC STRATEGIES IN AD AND PD IMAGING, BIOMARKERS AND TRANSLATIONAL ASPECTS MICROGLIA AND INFLAMMATION 13:45 14:15 CLOSING CEREMONY

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