Tristen Chun, MD, MS, MA

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1 Tristen Chun, MD, MS, MA Armand D. Versaci Research Scholar /Surgical Resident AYALA LAB Division of Surgical Research Rhode Island Hospital Brown Medical School Aldrich 226, 593 Eddy Street Providence, RI Phone # Fax# tchun1@lifespan.org Primary Research Field Innate lymphoid cells in sepsis and/or shock induced organ injury Education 2012 MD from Boston University School of Medicine, Boston, MA 2008 MA in Medical Sciences, Boston University, Boston, MA 2005 BS/MS in Cellular and Molecular Biology, Johns Hopkins University, Baltimore, MD Professional Experience 2014-present Alpert Medical School of Brown University, Armand D. Versaci Research Scholar, Providence, RI 2013-present Alpert Medical School of Brown University, Residency in General Surgery, Providence, RI Alpert Medical School of Brown University, Internship in General Surgery, Providence, RI Work Experience Boston University School of Medicine, Boston, MA (August 2011 Dec. 2011) Prosector, Instructor Led thorax/abdomen/pelvis section of anatomy course intended for first-year medical students Boston University School of Medicine, Boston, MA (August 2008 Feb. 2009) Medical Student Tutor Tutored fellow medical students in physiology, endocrinology, and immunology Massachusetts General Hospital, Boston, MA (May 2005 May 2008) Clinical Research Coordinator Worked on R01 EB grant involving lung cancer patients Co-authored two papers and published numerous abstracts Analyzed radiographic images to examine the role of FDG-PET in guiding radiation therapy in lung cancer patients 1

2 John Hopkins University, Baltimore, MD (September 2004 May 2005) Graduate Teaching Assistant Taught college level students molecular biology Led university level general biology laboratory courses Johns Hopkins University, Baltimore, MD (November 2000 May 2004) Undergraduate Research Assistant Worked on several NIH grants at the department of radiology Published numerous abstracts and had poster presentations Demonstrated changes in radioligand binding properties of the nicotinic cholinergic receptors following a chronic treatment of galantamine in mice Awards, Honors, Fellowships, Grants Publications: The Dr. Shoaib Sheikh Surgical Award For Best Clinical Research Manuscript, Alpert Medical School of Brown University Society for Vascular Surgery (SVS) Annual Meeting Chicago, IL o Recipient General Surgery Resident Travel Scholarship Award Introduction to Academic Vascular Surgery (IAVS) Conference Tampa, FL o Recipient General Surgery Resident Travel Scholarship Award Shock Society 38 th Annual Conference on Shock Denver, CO 2015 o Recipient New Investigator Travel Scholarship Award o Selected for Oral Presentation By and For New Investigators American College of Surgeons (ACS) Leadership and Advocacy Summit Washington, DC 2015 o Recipient Surgical Resident Travel Scholarship Award Society for Vascular Surgery (SVS) National Meeting Boston, MA 2014 o Recipient Travel Scholarship Award Society for Vascular Surgery (SVS) Annual Meeting Boston, MA 2014 o Winner Resident Surgical Skills Competition The Sidney Cooperband Award 2012 for the Highest Potential in Basic Science National Scholars Honor Society 2007 National Collegiate Taekwondo Association Champion 2003 National Society of Collegiate Scholars 2001 Peer Reviewed Publications: 1. Chun TT, Potz BA, Young WA. Chapter: Overview of the Molecular Pathways and Mediators of Sepsis. In: Sepsis: Definitions, Pathophysiology and the Challenge of Bedside Management, 1 st Edition. Ward NS and Levy MM (eds.). Springer Scientific Publications 2015 New York, NY. (In press) 2

3 2. Kamran SC, Chun TT, Ancukiewicz M, Niemeirko A, Fischman A, Choi NC. Esophagitis detected by restaging 18F-FDG-PET after radiation or chemiradiation for lung cancer. (under review) 3. Choi NC, Chun TT, Niemierko A, et al. Potential of (18) F-FDG PET toward personalized radiotherapy or chemoradiotherapy in lung cancer. Eur J Nucl Med Mol Imaging. 2013;40(6): Brasic JR, Bronson B, Chun TT, et al. Tardive dyskinesia. E-medicine. Online. Published Abstracts: 1. Rossi A-L, Le M, Matoso A, Chen Y, Xu S, Chun TT, Erickson CP, Chung C-S, Ayala A PD-L2 as new target to improve sepsis outcomes. Shock 45:(in press). 2. Heffernan DS, Chun TT, Fallon E, Cioffi WG, Ayala A inkt-cells modulate the pulmonary neutrophil response to sepsis. Shock 45:(in press). 3. Fallon EA, Heffernan DS, Chun TT, Muratore CS, Cioffi WG, Ayala A A role for Programmed cell death receptor-1 (PD-1) in regulating inkt-cell modulation of neonatal sepsis. Surg. Infect. 17:(in press). 4. Chun TT, Heffernan, D.S., Clarke, E., Cioffi, W.G., Chung, C.S., Ayala, A Invariant natural killer T (inkt) cells modulate expression of interleukin (IL)-25 in sepsis. J. Surg. Res. 190:(in press). 5. Chun TT, Tao T, Chung C, Cioffi WG, Heffernan DS, Ayala A Functional and phenotypic characteristics of peritoneal macrophages in mice deficient in invariant natural killer T (inkt) cells during polymicrobial sepsis. Shock 43: Chun TT, Heffernan DS, Hutchins NA, Cioffi WG, Chung CS, Ayala A Innate lymphoid cells in critical illness: is interleukin-33 (IL-33) a potential marker of sepsis? J Surg Res 188: Choi NC, Chun TT, Niemierko A, et al FDG uptake quantified with FDG PET days after radiotherapy or chemoradiotherapy in lung cancer is molecular-biomarker capable for predicting therapy outcome and identifying patients in need for timely salvage therapy. Int J Radiation Oncology Biology Physics Abstracts. 78:S34 (supplt. 3). 8. Chun TT, Choi NC, Fischman AJ Using image-derived radioactivity as a substitute for venous blood sampling when measuring fluoro-deoxyglucose utilization rate with the simplified kinetic method in F-FDG PET. J Nucl Med Abstracts. 48:399P (supplt 2). 3

4 9. Chun TT, Choi NC, Fischman AJ Correlation between the simplified kinetic method and standard uptake value in lung cancer before and after radiation treatment. J Nucl Med Abstracts. 48:399P (supplt 2). 10. Choi NC, Chun TT, Ancukiewicz M, et al FDG uptake at sequential intervals after radiotherapy (RT) or RT of chemo-radiotherapy (CT+RT) and its predictive value for clinical outcome of primary lung cancer. J Nucl Med Abstracts. 48:85P (supplt 2). Oral Presentations: 1. Chun TT, Tao T, Chung CS, Heffernan DS, Cioffi WG, Ayala A June 10 th. Short-talk/snap-shot presentation: Functional and phenotypic characteristics of peritoneal macrophages in mice deficient in invariant natural killer T (inkt) cells during polymicrobial sepsis. New Investigator Session at the 38th Annual Conference on Shock, Shock Society, Denver, CO. 2. Chun TT, Blakely AM, Cioffi WG, et al. Failure to develop a physiologic postoperative inflammatory response is associated with infectious complications following cancer surgery. New England Surgical Society 96 th Annual Meeting. Newport, RI. 3. Chun TT, Heffernan DS, Cioffi WG, et al. Post-operative infections are associated with increased risk of cardiac events in vascular patients New England Society for Vascular Surgery Annual Meeting. Newport, RI. 4. Chun TT. Surgical Anatomy of the Gastrointestinal Tract Nov 13 th. Southern New England Dietician Teaching Conference. Division of Surgical Nutrition, Department of Surgery, Brown University, Rhode Island Hospital. 5. Chun TT. Case Presentation: Blunt Abdominal Trauma Management of Biliary Tract Injury Mar 18 th. Beardsley Lectureship, Department of General Surgery, Brown University, Rhode Island Hospital. 6. Chun TT, Cates K, Luhrs A. Management/Prevention of Chronic Wounds Feb 11 th. General Surgery Junior Resident Conference Presentation. Brown University, Rhode Island Hospital. 7. Chun TT. Venous Thromboembolism: DVT/PE The Basics Nov 15 th. Medical Student Teaching Conference. Brown University, Rhode Island Hospital. 8. Chun TT. Chest pain and Dysrhythmia Jun 25 th. General Surgery Intern Boot Camp Presentation. Brown University, Rhode Island Hospital. 9. Chun TT. Liver Failure Apr 12 th. General Surgery Junior Resident Conference Presentation. Brown University, Rhode Island Hospital. 10. Chun TT, Granfield A. Basic Immunology Dec 3 rd. General Surgery Junior Resident conference Presentation. Brown University, Rhode Island Hospital. 4

5 11. Chun TT, Young W. General Anesthesia Agents and Techniques Aug 11 th. General Surgery Junior Resident Conference Presentation. Brown University, Rhode Island Hospital. Poster Presentations: 1. Chun, T.T., Tao, T., Chun, C.S, Cioffi WG, Heffernan DS, Ayala A. Functional and phenotypic characteristics of peritoneal macrophages in mice deficient in invariant natural killer T (inkt) cells during polymicrobial sepsis. Lifespan research day. Accepted and presented. 2015, October Chun TT, Tao T, Chung CS, Heffernan DS, Cioffi WG, Ayala A. Poster presentation: Functional and phenotypic characteristics of peritoneal macrophages in mice deficient in invariant natural killer T (inkt) cells during polymicrobial sepsis. New Investigator Session at the 37th Annual Conference on Shock, Shock Society, Charlotte, NC; 2015 June 10th. 3. Chun TT, Heffernan DS, Cioffi WG, et al. Post-operative infections are associated with increased risk of cardiac events in vascular patients Vascular Annual Meeting. Chicago, IL. 4. Wong DF, Chun TT, Musachio J, et al. PET/SPECT evidence of allosteric potentiation of galantamine in mice. 9 th International Conference on Alzheimer s Disease and Related Disorders Chun TT, Brasic JR, Morgan RH: Is research on human beings with Rett Syndrome ethical? 3 rd Rett Syndrome Symposium MEMBERSHIP IN SOCIETIES 2014-Present 2014-Present 2011-Present 2011-Present Society of Vascular Surgery (SVS) Candidate Resident Member Association for Academic Surgery (AAS) Candidate Member American College of Surgeons (ACS) Student/Resident Member American Medical Association (AMA) Resident Member Last updated: 2/8/2016 5

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