NIHR HTA Commissioning Board Minutes of the 58 th Meeting
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1 NIHR HTA Commissioning Board Minutes of the 58 th Meeting Date Tuesday & Wednesday March 2015 Place Danubius Hotel, London Present Members NETSCC, HTA Secretariat Apologies Professor Hywel Williams (Chair) Professor Jon Deeks (Deputy Chair) Professor Zarko Alfirevic Dr Amitava Banerjee Professor Judith Bliss Ms Isabel Boyer Ms Dawn Brown Professor David Fitzmaurice Professor Paul Griffiths Professor Angela Harden Professor Pat Hoddinott Professor Claire Hulme Professor Pip Logan Dr Joanne Lord Professor Danny McAuley Professor Bill McGuire Professor Dion Morton (from item 7 on Tuesday afternoon onwards) Professor Gail Mountain Professor Andrea Nelson Professor John Norrie Professor Barney Reeves Professor Chris Williams Dr Peter Davidson (Consultant Advisor) Mrs Stephanie Russell (Senior Programme Manager) Mr Mark Townsend (Programme Manager) Ms Linda Welch (Assistant Programme Manager) Ms Julie Herring (Administrator) Professor Tom Walley Professor Ed Juszczak Observers Day 1 Ms Elke Streit NETSCC research team, DTSP panel researcher (afternoon only) Day 2 Mr Neil Henderson NETSCC research team, EESC panel researcher Dr Sian Taylor-Phillips NIHR Postdoctoral Research Fellow, University of Warwick Page 1 of 11
2 4. Full proposals Commissioned Outlines seen in November /28/02 - CReST 2 - Colorectal Endoscopic Stenting Trial 2 DBMs: 1. Barney Reeves, 2. John Norrie, 3. Pat Hoddinott Out of the room: Jon Deeks, Ami Banerjee, David Fitzmaurice 14/28/02 - Professor James Hill /29/01 - A Community-Based Intervention to Improve Health-Related Quality of Life in Children of Parents with Serious Parental Mental Illness: Feasibility Study Panel: MPOH DBMs: 1. Pat Hoddinott, 2. Rob Howard, 3. Judith Bliss Out of the room: Caroline Watkins, Chris Williams 14/29/01 - Professor Kathryn Abel /167/01 - Steroid Induction Regimen for Juvenile Idiopathic Arthritis ( JIA) Panel: MNCH DBMs: 1. Bill McGuire, 2. David Fitzmaurice, 3. Judith Bliss Out of the room: Zarko Alfirevic, Danny McAuley, Caroline Watkins 14/167/01 - Dr Eileen Baildam Page 2 of 11
3 4.4 14/170/01 - Specific versus generic psychological therapy for adolescents with social anxiety disorder: A comparison of Clark & Wells condition-specific cognitive therapy adapted for adolescents, with the generic cognitive behaviour therapy that is currently used in adolescent services. Panel: MPOH DBMs: 1. Rob Howard, 2. Caroline Watkins, 3. John Norrie Out of the room: Jon Deeks, Chris Williams 14/170/01 - Professor Cathy Creswell /172/01 - The RESPECT Study (Randomised Evaluation of Sexual health Promotion Effectiveness informing Care and Treatment): a feasibility study of an intervention aimed at improving the Sexual Health of People with Severe Mental Illness Panel: PCCPI DBMs: 1. Angela Harden, 2. Chris Williams, 3. Dawn Brown, 4. Judith Bliss Out of the room: Rob Howard, Bill McGuire, Irwin Nazareth 14/172/01 Professor Elizabeth Hughes The board discussed the proposal and wished to see a resubmission 5. Full proposals Commissioned Resubmission from /135/02 - A multi-centre randomised controlled trial to compare the clinical and cost effectiveness of Lee Silverman Voice Treatment versus standard NHS speech and language therapy versus control in Parkinson's disease (PD COMM) Panel: EDAPT DBMs: 1. Judith Bliss, 2. Claire Hulme, 3. Barney Reeves Out of the room: Jon Deeks, Ami Banerjee, David Fitzmaurice, Pat Hoddinott, Pip Logan, Caroline Watkins, Chris Williams 10/135/02 - Professor Cath Sackley Page 3 of 11
4 6. Full proposal Commissioned Resubmission from July /142/04 - DIAbetic Macular Oedema and Diode Subthreshold micropulse laser (DIAMONDS) DBMs: 1. Rob Howard, 2. John Norrie, 3. Isabel Boyer, 4. Irwin Nazareth Out of the room: Danny McAuley, Barney Reeves 13/142/04 - Professor Noemi Lois 7. Full proposals Researcher-led Outlines seen in November /08/60 - Image directed redesign of bladder cancer treatment pathways Panel: DTSP DBMs: 1. Jo Lord, 2. Judith Bliss, 3. Pat Hoddinott Out of the room: Jon Deeks, Ami Banerjee, David Fitzmaurice, Paul Griffiths, Claire Hulme 14/08/60 - Professor Nicholas James /140/63 - Short: The ACL SNNAP Trial: Anterior Cruciate Ligament Surgery Necessity in Non Acute Patients Long: Comparison of the clinical and cost effectiveness of two management strategies for non-acute Anterior Cruciate Ligament (ACL) injury: Rehabilitation versus surgical Reconstruction DBMs: 1. Dion Morton, 2. Gail Mountain, 3. John Norrie Out of the room: Claire Hulme, Irwin Nazareth 14/140/63 - Professor John Beard Page 4 of 11
5 7.3 14/140/78 - ROMIO (Randomized Oesophagectomy: Minimally Invasive or Open): Definitive Trial. DBMs: 1. Dion Morton, 2. Andrea Nelson, 3. John Norrie Out of the room: Pat Hoddinott, Barney Reeves 14/140/78 - Mr Paul Barham 8. Vitamin D studies DBMs: 1. Rob Howard, 2. Danny McAuley, 3. Dion Morton, 4. Barney Reeves Out of the room: Angela Harden, Irwin Nazareth /116/501 - Vitamin D and Longevity (VIDAL) randomised trial of monthly oral vitamin D3 in healthy adults aged over 65 years. 08/116/501 - Professor Julian Peto /116/502 - Double-blind randomised placebo-controlled trial of daily vitamin D3 supplementation for the prevention of cancer and cardiovascular disease in older adults (Daily-D) 08/116/502 - Professor Adrian Martineau /49/138 - Large cost-effective randomized trial of high-dose vitamin D for disease provention in older people: UK vitamin D Study 14/49/138 - Professor Jane Armitage ACTION: The topic is to be further considered by Prioritisation 9. Seminar: From topic to advert: identifying and developing research priorities for HTA Page 5 of 11
6 10. Commissioned outline proposals resubmitted outlines /149/01 - Short title: Sensor Augmented Pump Pregnancy Intervention Trial Panel: MNCH DBMs: 1. Irwin Nazareth, 2. Andrea Nelson, 3. Bill McGuire Out of the room: Paul Griffiths, Chris Williams 13/149/01 - Helen Murphy ACTION: The brief is to be returned to panel /33/05 - Monitoring for neovascular AMD Reactivation at Home: the MONARCH study Panel: DTSP DBMs: 1. Ed Juszczak (W), 2. Gail Mountain, 3. Andrea Nelson Out of the room: Danny McAuley, Barney Reeves 14/33/05 - Dr Ruth Hogg ACTION: Return to the Prioritisation Group 11. Outline proposals Commissioned from calls closed 17 December /160 - Treatment of first-time traumatic shoulder dislocation DBMs: 1. Paul Griffiths, 2. Barney Reeves, 3. Dion Morton Out of the room: Claire Hulme 14/160/01 - Professor Jonathan Rees Page 6 of 11
7 /161 - Fibre for uncomplicated symptomatic diverticular disease of the large bowel Panel: PCCPI DBMs: 1. Pat Hoddinott, 2. Caroline Watkins, 3. Irwin Nazareth Out of the room: NONE 14/161/04 - Miss Sophie Medlin ACTION: Return to the Prioritisation Group /166 - Prevention of parastomal hernia formation DBMs: 1. Judith Bliss, 2. Angela Harden, 3. Isabel Boyer Out of the room: Jon Deeks, David Fitzmaurice, Pat Hoddinott, Dion Morton, Barney Reeves 14/166/01- Mr Neil Smart 14/166/07 - Mr Thomas Pinkney 14/166/10 - Professor Roger Motson /168 - Minimally invasive autopsy for fetuses and children based on a combination of post-mortem MRI and endoscopic autopsy examination Panel: DTSP DBMs: 1.Bill McGuire, 2. Dawn Brown, 3. Ami Banerjee Out of the room: Zarko Alfirevic, Paul Griffiths, Gail Mountain, Irwin Nazareth, Caroline Watkins 14/168/01 - Dr Laurence Abernethy Page 7 of 11
8 14/168/02 - Professor Neil James Sebire 14/168/03 - Dr Elspeth Whitby 12. Expressions of Interest Commissioned from calls closed 15 January /216 - Bioimpedance guided fluid management in dialysis patients Panel: DTSP DBMs: 1. Dion Morton, 2. John Norrie, 3. Caroline Watkins Out of the room: Jon Deeks, David Fitzmaurice, Paul Griffiths 14/216/01 - Professor Simon Davies /217 - What is the clinical and cost- effectiveness of nebulised antibiotics in reducing exacerbations in non-cystic fibrosis bronchiectasis? Panel: EESC DBMs: 1. Bill McGuire, 2. Pat Hoddinott, 3. Claire Hulme Out of the room: Hywel Williams, David Fitzmaurice, Paul Griffiths, Danny McAuley, Dion Morton, Irwin Nazareth 14/217/01 - Dr Adam Hill 14/217/02 - Dr Kelechi Ugonna Page 8 of 11
9 /218 - Surgical treatment of pressure ulcers DBMs: 1. Rob Howard, 2. Dion Morton, 3. John Norrie Out of the room: Paul Griffiths, Claire Hulme, Andrea Nelson 14/218/02 - Mr Pradeep Thumbikat 14/218/03 - Mr Henk Giele ACTION: Return to the Prioritisation Group /219 - Skeletal survey upon presentation of a linear skull fracture in infants and young children Panel: MNCH DBMs: 1. Ed Juszczak, 2. Danny McAuley, 3. Dawn Brown Out of the room: Hywel Williams, Paul Griffiths, Dion Morton, Gail Mountain, John Norrie. 14/219/01 - Dr Amaka Offiah /220 - Improving sleep for people with dementia living in the community Panel: MPOH DBMs: 1. Chris Williams, 2. Isabel Boyer, 3. Gail Mountain Out of the room: Judith Bliss, David Fitzmaurice, Robert Howard, Claire Hulme Irwin Nazareth, John Norrie, Caroline Watkins 14/220/01 - Dr Christopher Fox 14/220/06 - Professor Gillian Livingston Page 9 of 11
10 14/220/10 Associate Professor Dawn-Marie Walker 14/220/11 - Professor Kate Seers /221 - Z-drugs for sleep disturbance in people with dementia Panel: MPOH DBMs: 1. David Fitzmaurice, 2. Chris Williams, 3. Ed Juszczak Out of the room: Judith Bliss, Isabel Boyer, Rob Howard, John Norrie 14/221/02 - Dr George Savva 14/221/03 - Dr Anita McGrogan 14/221/06 - Professor Scott Weich /222 - Lithium or an antipsychotic as adjunctive therapy to an antidepressant for patients with treatment resistant depression Panel: MPOH DBMs: 1. Irwin Nazareth, 2. Chris Williams, 3. Angela Harden Out of the room: Judith Bliss, Isabel Boyer, Rob Howard, John Norrie 14/222/02 - Professor Anthony Cleare Page 10 of 11
11 /223 - Treating second and subsequent episodes of bacterial vaginosis Panel: PCCPI DBMs: 1. Zarko Alfirevic, 2. Judith Bliss, 3. Jo Lord Out of the room: Jon Deeks, David Fitzmaurice, Claire Hulme, Dion Morton, Irwin Nazareth 14/223/01 - Professor Jonathan Ross ACTION: Return to the Prioritisation Group 13. Summing up of day 2 and overall meeting outcomes Professor Williams thanked the members for their attendance and reminded them to keep all decisions confidential and that the next meeting would be on 10 & 11 March Page 11 of 11
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