Important Information Regarding Platelets Apheresis, LR Product Update

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1 1800 Alta Vista Ottawa, ON K1G 4J5 T F Important Information Regarding Platelets Apheresis, LR Product Update Customer Letter # Dear Colleague: This letter pertains to: Platelets Apheresis, LR Transfusion Instructions Label Canadian Blood Services (CBS) is implementing new automated technology for collecting Platelets Apheresis, LR. Platelets Apheresis, LR will be supplied in either one container, or where the product volume exceeds 400mL and/or the platelet yield is greater than 5x10 11 /unit, in two connected containers. The provision of Platelets Apheresis, LR in two containers improves platelet viability during storage by permitting more surface area for gas exchange. From a licensing perspective, Canadian Blood Services considers platelets stored in two bags as one product/unit. For transfusion of the entire unit, the platelets stored in two containers should be pooled into the primary container immediately prior to transfusion, as indicated on the transfusion instruction label that is adhered to the secondary container. Canadian Blood Services sites will apply this label (as shown) with instructions for the product to be pooled prior to transfusion. However, should the transfusion facility decide to issue the product in each container separately, internal procedures that include instructions to allow for identification of the separated containers should be followed.

2 Canadian Blood Services Actual Size If you have any questions regarding this matter, please do not hesitate to contact your local Canadian Blood Services. Attachments: 1. List of Regional s and Hospital Liaison Specialists 2. Site Implementation Schedule Sincerely, Dana V. Devine, Ph.D. Vice-President, Medical, Scientific and Research Affairs

3 Canadian Blood Services Attachment 1 CANADIAN BLOOD SERVICES MEDICAL CONSULTANT/DIRECTORS LISTED BY SITE BC & Yukon C.-B. et Yukon Edmonton Calgary Saskatchewan Winnipeg Site Localité North/Eastern Ontario & Nunavut Nord et Est de l Ontario et Nunavut London Central Ontario Centre de l Ontario Halifax New Brunswick Newfoundland & Labrador/ Nouveau-Brunswick et Terre-Neuve-et-Labrador Medical Consultant/Director Directeurs et conseillers médicaux Medical Consultant Conseiller médical Dr./D r Gershon Growe Directrice médicale Dr./D re Judy Hannon Dr./D r Dale Towns Dr./D r Edward C. Alport Directrice médicale Dr./D re Debra Lane Dr./D r Peter Lesley Dr./D r Robert Barr Dr./D r Morris Blajchman Dr./D r Ben Saxon Medical Consultant Conseillère médicale Dr./D re Irene Sadek Dr./D r Karl Misik SOCIÉTÉ CANADIENNE DU SANG DIRECTEURS ET CONSEILLERS MÉDICAUX LISTE PAR LOCALITÉ Phone Téléphone Courriel gershon.growe@blood.ca judy.hannon@blood.ca dale.towns@blood.ca ted.alport@blood.ca debra.lane@blood.ca peter.lesley@blood.ca bob.barr@blood.ca blajchman@mcmaster.ca ben.saxon@blood.ca irene.sadek@blood.ca karl.misik@blood.ca

4 Canadian Blood Services CANADIAN BLOOD SERVICES HOSPITAL LIAISON SPECIALIST LISTED BY REGION Regions Région Hospital Liaison Specialist Spécialiste de la liaison avec les hôpitaux SOCIÉTÉ CANADIENNE DU SANG SPÉCIALISTES DE LA LIAISON AVEC LES HÔPITAUX LISTE PAR RÉGION Phone Téléphone Courriel BC & Yukon C.-B. et Yukon Janet Unrau janet.unrau@blood.ca Alberta Colleen Young colleen.young@blood.ca Prairies Valerie Paulson valerie.paulson@blood.ca Northern & Eastern Ontario Denyse Tremblay denyse.tremblay@blood.ca Nord et Est de l Ontario Southern Ontario Sud de l Ontario Jon Fawcett jon.fawcett@blood.ca Central Ontario Centre de l Ontario Ahmed Coovadia ahmed.coovadia@blood.ca Atlantic (NS & NL) Atlantique (N.-É. et T.- Cheryl Doncaster cheryl.doncaster@blood.ca N.-L.) Atlantic (NB & PEI) Atlantique (N.-B. et Î.- P.-É.) Dorothy Harris dorothy.harris@blood.ca

5 Canadian Blood Services Attachment 2 As this will be staggered implementation with equipment from two vendors, you may see a mixed inventory of current and new product bags issued for a period of time. Site Implementation Schedule Date (Week of) Site - MCS+ Newfoundland Saskatchewan Toronto Ottawa BC/Y Calgary Winnipeg London Edmonton Sudbury Date (Week of) Halifax Feb-Mar 2008 Site - Trima New Brunswick Toronto Ottawa BC/Y

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