Network Science and Alzheimer s Disease

Transcription

1 2015 Scientific Symposium Network Science and Alzheimer s Disease Friday March 06, :00 am to 2:45 pm IU Health Neuroscience Center Goodman Hall Auditorium 355 W. 16 th Street Indianapolis, IN 46202

2 DESCRIPTION: Network Science and Alzheimer s Disease, IADC s 2015 scientific symposium is designed to help scientists and clinicians to better understand the complex multi-level systems involved in Alzheimer s disease--from altered brain connectivity and gene networks to the social networks surrounding patients and caregivers. 1 OBJECTIVES: At the conclusion of this program, participants will: Understand Alzheimer s disease from a network perspective. Learn about brain networks and the human connectome. Describe the social networks associated with aging and providing care to those with dementia. Recognize gene pathways and networks involved in memory. CALL FOR POSTERS: Attendees are invited to submit abstracts highlighting their research related to the symposium theme. Space is limited; 12 posters will be accepted and authors are asked to be present at their posters during the morning and lunch breaks. Please submit a 250 word abstract to iadc@iupui.edu by February 20 th. COURSE DIRECTORS: Mary Guerriero Austrom, PhD Wesley P. Martin Professor of AD Education, Department of Psychiatry and Director, IADC Outreach, Recruitment & Education Core Andrew J. Saykin, PsyD Raymond C. Beeler Professor of Radiology & Imaging Sciences and Director of the IADC, IUSM FEE: The symposium is offered free of charge, however, registration is required. Please visit our webpage to complete the registration form. You may also complete form attached here and Fax: dwert@iupui.edu Phone: PLANNING COMMITTEE: Indiana Alzheimer Disease Center Indiana University School of Medicine Andrew Saykin, PsyD Mary Guerriero Austrom, PhD Brandy R. Matthews, MD Jill R. Murrell, PhD Yvonne Lu, RN, PhD Donna Wert Bradley S. Glazier LOCATION: The Indiana Alzheimer Disease Center s 2015 Scientific Symposium on Alzheimer s Disease will be held in Goodman Hall Auditorium in the IU Health Neuroscience Center located at 355 W. 16 th Street, Indianapolis, IN Parking is available in Goodman Hall Garage, located at the corner of Missouri and 15 th Street. Parking is $5 per day. Bring parking ticket inside as automated payment machines are located inside the building. 1 While family members and the community are welcome to attend, the annual IADC Martin Family AD Caregiver Symposium will be held in October 2015.

3 Indiana Alzheimer Disease Center 2015 Scientific Symposium Network Science and Alzheimer s Disease Friday, March 06, 2015 IU Health Neuroscience Center - Goodman Hall Auditorium AGENDA 7:30 am Registration and Continental Breakfast Visit the scientific posters 8:00 am 8:15 am Welcome and Introductory Remarks Jill Murrell, PhD, Associate Professor, Departments of Pathology & Laboratory Medicine and Medical & Molecular Genetics, IUSM Alzheimer s Disease: A Network Perspective Andrew J. Saykin, PsyD, Raymond C. Beeler Professor of Radiology & Imaging Sciences and Director of the IADC, IUSM 8:45 am Social Networks, Aging and Cognitive Function KEYNOTE ADDRESS: Bernice A. Pescosolido, PhD, Distingushed Professor & Chancellor s Professor of Sociology, Co-Director, Indiana University Network Science Institute; Director, Indiana Consortium for Mental Health Services Research, IU Bloomington 9:45 am Break Visit the Scientific Posters and Meet the Researchers 10:15 am Brain Networks: The Human Connectome KEYNOTE Olaf Sporns, PhD, Distinguished Professor, Provost Professor, Robert H. Shaffer Chair, Co- ADDRESS: Director, Indiana University Network Science Institute; IU Bloomington 11:15 am Brain Connectomics: Pathology and Clinical Applications Joaquin Goñi, PhD, Associate Research Scientist, IU Network Science Institute, Adjunct Associate Research Professor of Radiology & Imaging Sciences, IUSM 12:00 pm Lunch (provided) Visit the Scientific Posters and Meet the Researchers 1:00 pm 1:45 pm 2:30 pm Genes, Pathways and Networks for Memory and Neurodegenerative Diseases Vijay Ramanan, PhD, Post doctoral researcher and 4 th year MD student, IUSM Gene Networks Related to Neuroimaging and Biomarker Phenotypes Li Shen, PhD, Associate Professor of Radiology and Imaging Sciences, Department of Radiology and Imaging Sciences, IUSM Closing Remarks and Program Evaluation Jill R. Murrell, PhD Certificates of Attendance will be available at end of the day upon request and completion of the evaluation form.

4 Faculty Andrew Saykin, PsyD, is the Raymond C. Beeler Professor of Radiology and Imaging Sciences and Director of both the Indiana Alzheimer Disease Center (IADC), and the IU Center for Neuroimaging, Indiana University School of Medicine (IUSM). The IADC is one of 27 centers sponsored by the National Institute on Aging. Dr. Saykin is a neuropsychologist whose research focuses on using advanced brain imaging and genetics to understand disorders affecting memory and cognition. Advances in brain imaging have become increasingly important for the early detection of disorders leading to dementia. Bernice A. Pescosolido, PhD, is Distinguished Professor of Sociology at IU Bloomington, Director of the Indiana Consortium for Mental Health Services Research (ICMHSR), and Co-Director of the newly established Indiana University Network Science Institute (IUNI). She has focused her research and teaching on social issues in health, illness, and healing. More specifically, her research addresses how social networks connect individuals to their communities and to institutional structures, providing the "wires" through which people s attitudes and actions are influenced. Her research encompasses three basic areas: health care services, stigma, and suicide research. In the early 1990s, she developed the Network-Episode Model, which was designed to focus on how individuals come to recognize and respond to the onset of health problems, and use health care services. It has provided new insights to understanding the patterns and pathways to care, adherence to treatment and the outcome of health care. As a result, she has served on advisory panels at the NRC, NIMH, NCI, NHLBI, NIDRR, OBSSR, and presented at congressional briefings. Olaf Sporns, PhD, is Distinguished Professor in the Department of Psychological and Brain Sciences; Provost Professor, Robert H. Shaffer Chair of the Computational Cognitive Neuroscience Lab, and Co-Director, IU Network Science Institute (IUNI), at IU Bloomington. After receiving an undergraduate degree in biochemistry, he earned a PhD in neuroscience at Rockefeller University and then conducted postdoctoral work at The Neurosciences Institute in New York and San Diego. His main research area is theoretical and computational neuroscience, with a focus on complex brain networks. He has authored over 160 peer-reviewed publications as well as the recent books Networks of the Brain and Discovering the Human Connectome, both published by MIT Press. Dr. Sporns was awarded a John Simon Guggenheim Memorial Fellowship in 2011 and elected Fellow of the American Association for the Advancement of Science in Joaquín Goñi, PhD is an Associate Research Scientist at Indiana University Network Science Institute and Adjunct Associate Research Professor of Radiology and Imaging Sciences at the IUSM. Also, he is an investigator for the Center for Neuroimaging and the IADC. Dr. Goñi earned a PhD from the University of Navarra School of Sciences (Spain) in 2008 and completed a post-doctoral fellowship in the Functional Neuroimaging Laboratory in the Center for Applied Medical Research (Spain). From 2011 to 2014, he was in Dr. Olaf Sporns' laboratory as a Research Associate in the Department of Psychological and Brain Sciences at IU Bloomington. As a computational neuroscientist with expertise in complex systems, his current research is focused on the application of frameworks such as graph theory, information theory or fractal theory in neuroscience with a specific focus in neuroimaging. Currently, Dr. Goñi's research is focused on the human connectome, including network analyses of structural and functional connectivity during different tasks under various disease conditions, with an emphasis on neurodegenerative diseases. Vijay Ramanan, PhD, is a post doctoral researcher and 4th year MD student at IUSM. His interests are in understanding the genetic predictors of Alzheimer s disease and other neurodegenerative diseases and normal cognitive aging. His research utilizes neuroimaging, blood and CSF biomarkers, and cognitive assessment phenotypes from several large human study cohorts. Li Shen, PhD, is an Associate Professor of Radiology and Imaging Sciences at IUSM. He is a member of the Center for Neuroimaging, the Center for Computational Biology and Bioinformatics, and the Stark Neurosciences Research Institute at IUSM. He is an elected member of the MICCAI Society Board of Directors. His research interests include medical image computing, bioinformatics, data mining, and network science. The central theme of his lab is focused on developing computational and informatics methods for integrative analysis of multimodal imaging data, high throughput "omics" data, fluid and cognitive biomarker data, and rich biological knowledge such as pathways and networks, with applications to various complex disorders. The ultimate goal is to improve mechanistic understanding of disease processes and treatment responses for early diagnosis and treatment for complex disorders.

5 REGISTRATION FORM Indiana Alzheimer Disease Center 2015 Scientific Symposium Network Science and Alzheimer s Disease Friday, March 06, 2015 The program is offered free of charge; however, REGISTRATION is required. Register online at iadc.iupui.edu/current-events/ or send this form to: Indiana Alzheimer Disease Center 355 W. 16th Street, Suite 2800, Indianapolis, IN Phone: (317) Fax: (317) dwert@iupui.edu TITLE: (Check all that apply) MD PhD PsyD RN MSW CNA CAREGIVER Other Specialty: LAST NAME: FIRST NAME: MIDDLE INITIAL: BUSINESS NAME : MAILING ADDRESS STREET: CITY: STATE: ZIP: DAYTIME PHONE: CERTIFICATE OF ATTENDANCE: available upon completion of evaluation form ADDRESS: Yes, I would like a certificate No certificate needed LUNCH PROVIDED Please check if you have a special dietary need: Vegetarian Dairy Free Gluten Free Other How did you hear about the IADC 2015 Scientific Symposium: IADC Website Newsletter IADC Facebook IADC Twitter Colleague IU/IUPUI News source Flyer (location)

6 Indiana Alzheimer Disease Center staff wants everyone to feel welcome at this event. If you have a disability and need an accommodation to participate in this program, IADC staff will try to provide it. Please contact us at (317) with your needs 72 hours prior to the event. LODGING AND ACCOMMODATIONS Lodging information may be obtained by contacting the Indianapolis Convention and Visitors Association at (800) 556-INDY(4639) or LOCATION: IU Health Neuroscience Center Goodman Hall Auditorium 355 W. 16th Street Indianapolis, IN Directions: Note: Entrance and parking garage are located off of 15th Street, between Senate Avenue and Missouri Avenue. Garage parking is available at a cost of $5 maximum per day. Payment may be made by cash or credit card inside the building, prior to returning to your vehicle. From the North I-65 South to Exit 115 toward 21st Street. Turn left on 21st Street. Turn right onto Senate Boulevard. Continue on Senate Boulevard past IU Health Methodist Hospital and cross 16th Street. Turn left onto 15th Street and follow the signs for parking in the onsite garage. -OR- I-69 South to I-465, south to I-70, west to I-65 North to Exit 115 toward 21st Street. On the exit ramp, keep right at the fork and merge onto Senate Boulevard. Continue on Senate Boulevard past IU Health Methodist Hospital and cross 16th Street. Turn left onto 15th Street and follow the signs for parking in the onsite garage. From the South I-65 north to Exit 115 toward 21st Street. On the exit ramp, keep right at the fork and merge onto Senate Boulevard. Continue on Senate Boulevard past IU Health Methodist Hospital and cross 16th Street. Turn left onto 15th Street and follow the signs for parking in the onsite garage. From the East I-70 (or I-74) to I-65 north to Exit 115 toward 21st Street. On the exit ramp, keep right at the fork and merge onto Senate Boulevard. Continue on Senate Boulevard past IU Health Methodist Hospital and cross 16th Street. Turn left onto 15th Street and follow the signs for parking in the onsite garage. From the West I-70 east to I-65 north (the two join temporarily) to Exit 115 toward 21st Street. On the exit ramp, keep right at the fork and merge onto Senate Boulevard. Continue on Senate Boulevard past IU Health Methodist Hospital and cross 16th Street. Turn left onto 15th Street and follow the signs for parking in the onsite garage. -OR - US-136 turn east (right) onto Crawfordsville Road, or take I-74 which becomes Crawfordsville Road. Follow Crawfordsville Road (Speedway) which becomes 16th Street. Follow 16th Street to Senate Boulevard/Missouri Avenue. Turn south (right) onto Missouri Avenue. Turn east (left) onto 15th Street and follow the signs for parking in the onsite garage.