CARDIOVASCULAR RISK REDUCTION

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1 Jointly provided by the NYU Post-Graduate Medical School, the New York Chapter of the American College of Physicians and the Northeast Lipid Association Co-organized by the Division of Cardiology and the Division of Endocrinology, Diabetes, and Metabolism Advances in CARDIOVASCULAR RISK REDUCTION FRIDAY, MAY 8, 2015 NYU Langone Medical Center REGISTER ONLINE AT:

2 ADVANCES IN CARDIOVASCULAR RISK REDUCTION MAY 8, 2015 NYU LANGONE MEDICAL CENTER COURSE DESCRIPTION This one-day course will cover state-of-the-art management of patients with cardiovascular risk factors, with a focus on prevention. This year s program includes topics such as PCSK9, Imaging in Atherosclerosis, APOC3, Triglycerides and Cardiovascular Disease Risk, GLP1 and SGLT2 inhibitors in the treatment of diabetes, pharmaceutical therapies for weight loss, and updates on the treatment of platelet disorders and ischemia. Each year this course includes a researchoriented presentation that highlights benchto-bedside relevance. This year the featured research-oriented presentation will focus on the latest in atherosclerosis laboratory research. TARGET AUDIENCE Internists, family practitioners, cardiologists, general practice, endocrinologists, nurse practitioners, and dietitians with an interest in the prevention of heart disease STATEMENT OF NEED This year s program addresses practice gaps in the treatment of diabetes, obesity, atherosclerosis, coronary artery disease and dyslipidemia. Recent studies have made it necessary to update physicians on: The effects of personalized diabetic care in preventing health complications and improving the quality of life for millions of Americans New therapies, including GLP1 and SGLT2 inhibitors, that offer novel therapeutic strategies for the treatment of diabetes Several new drugs that were recently made available in the treatment of obesity Imaging modalities that are available for assessing atherosclerosis risk as well as treatment of atherosclerosis Current concepts (low dose aspirin therapy) and new agents in anti-platelet therapy The critical role PCSK9 plays in modulating LDL levels The potential for APOC3 therapies, as a potential new class of drugs, to protect against coronary artery disease EDUCATIONAL OBJECTIVES At the conclusion of this activity, participants should be able to: Discuss how GLP1 and SGLT2 inhibitors can be utilized to treat diabetics Describe current and novel agents for obesity treatment Incorporate noninvasive testing modalities for atherosclerosis in assessing risk for development as well as identification of subclinical disease Summarize the role of anti-platelet agents in preventing cardiovascular events and their efficacy and safety in light of recent clinical trials Describe how, PCSK9 modulates LDL levels and how PCSK9 expression is affected by statin treatment Describe recent APOC3 studies and how the results of these studies have eludicated the role of APOC3 on triglyercide levels and CAD risk Describe current mechanisms of atherosclerosis including new factors regulating LDL clearance ACCREDITATION STATEMENT This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of the NYU Post-Graduate Medical School, the NY Chapter American College of Physicians and the Northeast Lipid Association. The NYU Post-Graduate Medical School is accredited by the ACCME to provide continuing medical education for physicians. CREDIT DESIGNATION STATEMENT The NYU Post-Graduate Medical School designates this live activity for a maximum of 7.50 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

3 DISCLOSURE STATEMENT The NYU Post-Graduate Medical School adheres to ACCME accreditation requirements and policies, including the Standards for Commercial Support regarding industry support of continuing medical education. In order to resolve any identified conflicts of interest, disclosure information is provided during the planning process to ensure resolution of any identified conflicts. Disclosure of faculty and commercial relationships, as well as the discussion of unlabeled or unapproved use of any drug, device or procedure by the faculty, will be fully noted at the meeting. COURSE FACULTY COURSE DIRECTOR Arthur Z. Schwartzbard, MD, FACC Assistant Professor of Medicine Director, Clinical Lipid Research NYU Langone Center for the COURSE PLANNERS Edward Fisher, PhD, MPH, MD The Leon H. Charney Professor of Cardiovascular Medicine and Professor of Pediatrics and Cell Biology Director, Marc and Ruti Bell Vascular Biology and Disease Program Director, NYU Langone Center for the Clarissa and Edgar Bronfman, Jr. Professor of Endocrinology Lawrence Phillips, MD Assistant Professor of Medicine James Underberg, MS, MD Clinical Assistant Professor of Medicine Director, Bellevue Hospital Lipid Center NYU Langone Center for Prevention of Cardiovascular Disease GUEST FACULTY Silvio E. Inzucchi, MD Professor of Medicine Clinical Chief, Endocrinology Medical Director Yale Diabetes Center Yale University New Haven, CT Barbara Kahn, MD Professor of Medicine Harvard Medical School Vice Chair, Department of Medicine Beth Israel Deaconess Medical Center Boston, MA Matthias Nahrendorf, MD, PhD Associate Professor Harvard Medical School Boston, MA NYU SCHOOL OF MEDICINE FACULTY Sripal Bangalore, MD, MHA Associate Professor of Medicine Jeffrey S. Berger, MD Assistant Professor of Medicine and Surgery (Vascular Surgery) Edward Fisher, PhD, MPH, MD The Leon H. Charney Professor of Cardiovascular Medicine and Professor of Pediatrics and Cell Biology Director, Marc and Ruti Bell Vascular Biology and Disease Program Director, NYU Langone Center for the Eugenia Gianos, MD Assistant Professor of Medicine Co-Clinical Director, NYU Langone Center for the Prevention of Cardiovascular Disease Director, Preventive Cardiology Fellowship Program Director, Preventive Cardiology Consult Service Clarissa and Edgar Bronfman, Jr. Professor of Endocrinology Dennis A. Goodman, MD, FACP, FACC, FCCP, ABIHM Clinical Associate Professor of Medicine Director of Integrative Medicine Jonathan D. Newman, MD, MPH Instructor of Medicine Richard Stein, MD Professor of Medicine Director, Exercise, Nutrition and Cardiovascular Disease Program NYU Langone Center for the James Underberg, MS, MD Clinical Assistant Professor of Medicine Director, Bellevue Hospital Lipid Center NYU Langone Center for Prevention of Cardiovascular Disease Howard S. Weintraub, MD Clinical Professor of Medicine Clinical Director NYU Langone Center for Prevention of Cardiovascular Disease

4 REGISTER ONLINE AT: LOCATION NYU Langone Medical Center 550 First Avenue (31st St.) Alumni Hall, Farkas Auditorium HOTEL ACCOMMODATIONS Rooms are in very heavy demand in New York City; we urge you to make your reservations early. You may obtain a list of hotels located near NYU Langone Medical Center by visiting our website: MAILING ADDRESS AND CONTACT INFORMATION: Registration Office NYU Post-Graduate Medical School 577 First Avenue, Room Phone: (212) Fax: (212) PARKING For information, please visit We cannot validate parking for registrants. COURSE SCHEDULE 7:45am Registration & Continental Breakfast 8:30 KAYDEN LECTURE APOC3, Triglycerides and Cardiovascular Disease Risk 9:00 PCSK9 Update Howard S. Weintraub, MD 9:30 Imaging Insights in Atherosclerosis Matthias Nahrendorf, MD, PhD 10:00 Coffee Break 10:15 Weight Loss: New Pharmaceutical Therapies James Underberg, MS, MD 10:45 Panel Discussion/Case Review Above Speakers & Medical Staff of the Center for the Prevention of Cardiovascular Disease 11:45 Lunch Case Conference: Navigating the Challenging Cases in Cardiovascular Disease Risk 12:45pm Antiplatelet Therapy in 2015: What s New? Jeffrey S. Berger, MD 1:15 CHARNEY LECTURE Ischemia Update Sripal Bangalore, MD, MHA 1:45 A Novel Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-Inflammatory Effects Barbara Kahn, MD 2:15 Atherosclerosis: Basic Science Update and Clinical Implications Edward Fisher, PhD, MPH, MD 2:45 SGLT2 Inhibitors in Type 2 Diabetes Silvio E. Inzucchi, MD 3:15 Panel Discussion/Case Review Above Speakers & Medical Staff of the Center for the Prevention of Cardiovascular Disease 4:15 Closing Remarks 4:30pm Adjourn Dr. Ira J. Goldberg s presentation has been designated as the 9th Annual Herbert Kayden Lecture, in recognition of Dr. Kayden s distinguished research career in lipid metabolism at NYU Langone Medical Center. Dr. Sripal Bangalore s presentation has been designated as the 4th Annual Leon H. Charney Lecture. This lecture series features outstanding basic, translational or clinical research by a member of the Leon H. Charney Division of Cardiology in an area related to the prevention of cardiovascular disease.

5 REGISTRATION FORM REGISTER ONLINE AT: Advances in Cardiovascular Risk Reduction May 8, 2015 NYU Langone Medical Center, Alumni Hall, Farkas Auditorium 550 First Avenue (31st St.), After 12pm on May 6, 2015, only onsite registration is available, provided the course has not reached capacity. Onsite registrants will incur an additional $20 charge and will receive a receipt by in 1-2 weeks. PLEASE PRINT CLEARLY IN BLOCK LETTERS AND NUMBERS Name Address City State Zip (REQUIRED FOR CME CREDIT) Day Phone Fax Degree Specialty COURSE FEES Full Fee: $175 Reduced Fee: $60* NYU Langone Faculty & Staff: $60 (must provide valid NYU Langone ID) Residents & Fellows: Waived** * Reduced fee applies to alumni, former residents and fellows; physicians employed by the Department of Veterans Affairs Medical Center; full-time active military personnel; nurse practitioners; retired physicians; and all other non-physician healthcare professionals ** To register at the waived fellow rate, you must submit a letter on official stationery from the Chief of Service stating that you are a fellow in a full-time approved training program to cme@nyumc.org. METHODS OF PAYMENT Cash, and phone registration are not accepted. If faxing, do not mail or refax. This will only result in a duplicate charge to your account. Registration is non-transferable. Check in U.S. Dollars only: $ Payable to NYU Post-Graduate Medical School Credit Card Payment (see below) International Postal Money Order: $ Foreign registrants, including those from Canada, must pay by International Postal Money Order or credit card. PAYMENT BY CREDIT CARD Credit card payments may be faxed to (212) Amount to be charged: $ Bill to: Visa MasterCard American Express Credit Card Number: Card Member s Name: Exp Date: CVV Code: Signature: SEND TO: Registration Office NYU Post-Graduate Medical School 577 First Avenue, Room REFUND POLICY: In order to request a refund, you must complete and submit our online refund form no later than 14 days prior to the first day of the course. An administrative fee of $75 will be deducted from your refund. Cancellations or no-shows after this date are not eligible for a refund. Fax and cancellations are not accepted. COURSE CANCELLATION POLICY: In the unusual circumstance that this course is cancelled, two weeks notice will be given and tuition will be refunded in full. The NYU Post- Graduate Medical School is not responsible for any airfare, hotel or other costs incurred. Special needs or requests:

6 Post Graduate Medical School 577 First Avenue, The NYU Langone Center for the Prevention of Cardiovascular Disease is a component of the Leon H. Charney Division of Cardiology and the Cardiac and Vascular Institute. To learn more about the NYU Langone Center for the, visit Advances in CARDIOVASCULAR RISK REDUCTION FRIDAY, MAY 8, 2015 NYU Langone Medical Center Non-Profit Org. U.S. Postage PAID Permit #8167

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