Samantha K. Holden, MD East 17th Avenue Campus Box B185 Aurora, CO Phone:

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1 EDUCATION Samantha K. Holden, MD University of Colorado Anschutz Medical Campus, Colorado Clinical and Translational Sciences Institute, Clinical Sciences Graduate Program, M.S. in Clinical Science. Expected completion May Stony Brook University School of Medicine, Stony Brook, New York. M.D. May 2010 New York University, College of Arts and Science, New York, New York. B.S. in Neural Science, Minors in Philosophy and Psychology. Cum Laude, May 2006 POSTGRADUATE TRAINING University of Colorado Anschutz Medical Campus, Aurora, Colorado. Behavioral Neurology Fellowship, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Movement Disorders Fellowship, Rush University Medical Center, Chicago, Illinois. Neurology Residency, Rush University Medical Center, Chicago, Illinois. Internal Medicine Internship, ACADEMIC APPOINTMENTS Assistant Professor, Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, Start Date July 1, 2017 EMPLOYMENT Staff Neurologist, Fee-Basis, Denver VA Medical Center, CERTIFICATION AND LICENSURE Diplomate, American Board of Neurology and Psychiatry (Neurology), 2014-present Diplomate, United Council for Neurologic Subspecialties, Behavioral Neurology and Neuropsychiatry, 2016-present State of Colorado Medical License, 2013-present State of Illinois Medical License, HONORS AND AWARDS International Congress Travel Grant Award, Movement Disorders Society, 2017 Resident Scholarship to the Annual Meeting, American Academy of Neurology, 2014 Rush Neurology Resident Teacher of the Year Award, 2013 New York University Founder s Day Award,

2 United Hospital Fund Volunteer Service Award 2005 NYU President s C-Team Century Club Award, 2004 Samantha K. Holden, MD PROFESSIONAL SOCIETY MEMBERSHIPS American Neuropsychiatric Association, 2016-present International Parkinson and Movement Disorder Society, 2014-present Colorado Society of Clinical Neurologists, 2014-present American Academy of Neurology, 2007-present President, Student Interest Group in Neurology, Stony Brook University School of Medicine chapter, TEACHING EXPERIENCE Nervous System block, University of Colorado School of Medicine, August 2016 Delirium and Dementia Camp Neuro, University of Colorado School of Medicine, June 2015, June 2016 Introduction to Behavioral Neurology Neuropsychological Assessment Physical Medicine and Rehabilitation Residency Didactics, University of Colorado School of Medicine, June 2016 A Practical Approach to Dementia Diagnosis and Treatment General Neurology Teaching Elective, Rush University Medical Center, Developed and refined a new elective rotation for senior neurology residents that focused on teaching medical students on the General Neurology Service Teaching Assistant, Nervous System Block, Rush Medical College, Spring 2014 Led small group case-based discussions, assisted with brain gross anatomy sessions, and contributed clinical knowledge to basic science lectures MENTORING EXPERIENCE Regis University Neuroscience Undergraduate Internship Mentor Abigail Simpson, Graduate School, University of Colorado Anschutz Medical Campus, Masters Thesis Defense Committee Hannah Redwine, 2017 RESEARCH EXPERIENCE Fellowship Research Project, University of Colorado Denver, Sections of Movement Disorders and Behavioral Neurology,

3 Performance-based Functional Assessment for Evaluation of Cognitive Impairment in Parkinson s Disease, Mentor: Benzi Kluger, MD Residency Research Project, Rush University Medical Center, Division of Movement Disorders, Neuropsychological Assessment for Diagnosis of Mild Cognitive Impairment in Parkinson s Disease, Mentor: Jennifer Goldman, MD Research Assistant, New York University, Department of Cognitive Neuroscience, Phelps Lab, Effect of Emotional Information on Working Memory, PI: Sara Levens, PhD RESEARCH SUPPORT Source: Michael J. Fox Foundation (MJFF) Project Title: Validation of a performance-based assessment of functional ability related to cognition in Parkinson s disease Role: Principal Investigator Purpose: Evaluate the ability of the UCSD Performance-Based Skills Assessment to identify functional impairment as related to cognition in Parkinson s disease Total Award: $165,975 Period of Support: Source: Patient Centered Outcome Research Institute (PCORI): Improving Healthcare Systems Project Title: Does Outpatient Palliative Care Improve Patient-Centered Outcomes in Parkinson's Disease? Role: Co-I Purpose: This proposal supports a 3 center randomized controlled trial to evaluate the effectiveness of outpatient team-based palliative care versus usual care for Parkinson s disease. Total Award: $1,965,022 Period of Support: Source: ProjectSpark Spark Grant Project Title: Home-based Neurologic music therapy for management of behavioral symptoms of dementia Role: Co-PI Purpose: This award will provide funding to conduct a feasibility trial for empowering caregivers of community living persons with dementia to improve behavioral management and avoid nursing home placement Total Award: $7,200 Period of Support: REVIEW AND REFEREE WORK Ad hoc reviewer, The Journal of Neuropsychiatry and Clinical Neurosciences Ad hoc reviewer, Brain and Cognition Ad hoc reviewer, Parkinsonism & Related Disorders PUBLICATIONS 3

4 Peer Reviewed Journal Articles Holden SK, Finseth T, Sillau S, Berman BD. Progression of MDS-UPDRS scores in de novo Parkinson disease from the Parkinson s Progression Markers Initiative. Movement Disorders 2017, submitted. Holden SK, Jones WE, Baker KA, Boersma IM, Kluger BM. Outcome measures for Parkinson s disease dementia: a systematic review. Movement Disorders Clinical Practice 2016 Jan-Feb;3(1):9-18. Goldman JG, Holden S, Ouyang B, Bernard B, Goetz CG, Stebbins GT. Diagnosing PD-MCI by MDS Task Force criteria: how many and which neuropsychological tests? Movement Disorders 2015 Mar;30(3): Goldman JG, Holden S, Bernard B, Ouyang B, Goetz CG, Stebbins GT. Defining optimal cutoff scores for cognitive impairment using MDS Task Force PD-MCI criteria. Movement Disorders 2013 Dec;28(14): Invited Review Articles Goldman JG, Holden S. Treatment of psychosis and dementia in Parkinson s disease. Current Treatment Options in Neurology 2014 Mar;16(3):281. Abstracts Holden SK, Medina LD, Hoyt B, Sillau SH, Goldman JG, Weintraub D, Kluger BM. Validation of a performance-based assessment of functional ability related to cognition in Parkinson s disease. Movement Disorders Persenaire MJ, Holden S, Kluger BM, Woodcock JH, Anderson CA, Filley CM. Palliative Care: A Novel Approach to Patients with Neurodegenerative Disease. The Journal of Neuropsychiatry and Clinical Neuroscience 2016;28:e57-e58. Holden S, Lewis SL. Timeliness of neurology consultations in the emergency department: a quality evaluation. Neurology 2014 Apr;82(10)Supplement. Book Chapters Holden SK, Hall DA (2017). Ataxia. In Hall D and Barton B (Eds.), Non-Parkinsonian Movement Disorders (pp 68-79). West Sussex, UK: Wiley-Blackwell. Holden S, Goldman JG (2016). Parkinson s disease. In Friedman H (Ed.), Encyclopedia of Mental Health, 2 nd Edition (pp ). Waltham, MA: Elsevier. INVITED LECTURES AND PRESENTATIONS Local The ABCs of Alzheimer's Disease Diagnosis: A Primer for Families. Alzheimer's Association Education Symposium, Denver, CO. October

5 REM Behavior Disorder: From Dreams to Neurodegeneration. Invited speaker, University of Colorado Behavioral Neurology Conference, Aurora, CO. September 2016 Non-motor symptoms in Parkinson s disease. Invited speaker, Parkinson s Association of the Rockies E3: Educate, Empower, Energize 4 th Annual Conference, Aurora, CO. September 2016 Cognitive Assessment in Parkinson s disease. Invited speaker, University of Colorado Movement Disorders Center Conference, Aurora, CO. August 2016 Ahead of the Curve: Non-motor symptoms in Parkinson s disease. Invited speaker, Parkinson Association of the Rockies. April 2015, May 2016, June 2016 Treatment options for Parkinson s disease. Invited speaker, Parkinson Association of the Rockies, Aurora Support Group, April 2016 Cognitive Changes in Parkinson s disease. Invited speaker, Parkinson Association of the Rockies. August 2014, March 2015, November 2016 Adult-onset leukodystrophies presenting as movement disorders. Department of Neurology Grand Rounds, University of Colorado School of Medicine, Aurora, CO. December 2014 Validation of MDS Task Force Level II Diagnostic Criteria for Mild Cognitive Impairment in Parkinson s disease. Department of Neurology Grand Rounds: Resident Research Forum, Rush University Medical Center, Chicago, IL. May 2014 National Determining Optimal Cutoff Scores and Neuropsychological Tests for the Diagnosis of Mild Cognitive Impairment in Parkinson's disease. Platform presentation at American Academy of Neurology Annual Meeting, Philadelphia, PA, April 2014 Timeliness of neurology consultations in the emergency department: a quality evaluation. Poster presentation at American Academy of Neurology Annual Meeting, Philadelphia, PA, April 2014 A Loss of Language: A Case of Landau-Kleffner Syndrome. Case presentation at Neurology Resident Scholar Program, Scottsdale, AZ, September

Samantha K. Holden, MD East 17th Avenue Mail Stop F429 Aurora, CO Phone:

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