WHY SLEEP MATTERS: SLEEP HEALTH AND HYGIENE. KYRA P CLARK, MD, FACP Medical Director, Sleep Diagnostics Morehouse School of Medicine October 15, 2016
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1 WHY SLEEP MATTERS: SLEEP HEALTH AND HYGIENE KYRA P CLARK, MD, FACP Medical Director, Sleep Diagnostics Morehouse School of Medicine October 15, 2016
2 OBJECTIVES Discuss the prevalence sleep deprivation in the United States Review the association between sleep, health and inflammation Define sleep hygiene Understand and adapt good sleep hygiene measures
3 INSUFFICIENT SLEEP IS A PUBLIC HEALTH PROBLEM
4 SLEEP DEPRIVATION PREVALENCE Effects million Americans 1 Sleep Apnea Insomnia Restless Leg Syndrome Narcolepsy Chronic Sleep Deficiency 1 and 3 adult Americans <7hrs/night 2 Behaviorally Induced: poor sleep hygiene Colten HR, Altevogt BM. Sleep disorders and sleep deprivation: an unmet public health problem. Washington, DC: National Academies Press, Centers for Disease Control and Prevention (CDC). Effect of short sleep duration on daily activities United States, MMWR Morb Mortal Wkly Rep 2011; 60:
5 AVERAGE SLEEP TIMELINE Year Study Average Sleep Time American Cancer Society hours per night Late 1960 s Tune, 1968/1969 4,5 Hammond, hours per night 2008 National Sleep Foundation 7 6hrs and 40min (weeknights) Lombardi, 2010 (National Health Interview Survey) 8 <6 hours per night (40.6 million workers) 2010 National Sleep Foundation 9 <7hrs on weeknights across all racial groups
6 AVERAGE SLEEP TIME BY ETHNICITY Weeknight Weekend Caucasian African-Americans Asian Hispanic Data from the National Sleep Foundation, Sleep in American Poll 2010 (National Sleep Foundation, Washington, D.C)
7 AVERAGE SLEEP BY GENDER Percentage of adults reporting an average 6 h of sleep in 1985 and in Data from the National Health Interview Survey, , and Schoenborn 11. Luyster FS et al. Sleep: a health perspective. SLEEP 2012; 35(6): 728
8 SLEEP DEPRIVATION: PERFORMANCE AND HEALTH CONSEQUENCES
9 Tracy Morgan Wal-Mart Accident: Driver made deliveries to Wal-Mart stores in New Jersey, Delaware and Pennsylvania before the accident 13 hours, 32 minutes later. Federal rules limit interstate commercial drivers to 14-hour shifts before they must rest.
10 The Exxon Valdez oil spill occurred in Prince William Sound, Alaska, on March 24, 1989, when the Exxon Valdez, struck Prince William Sound s Bligh Reef and spilled 260,000 to 750,000 barrels of crude oil. The Three Mile Island accident in It was the most significant accident in the history of the USA commercial nuclear power generating industry. Between the hours of 4 and 6 a.m., Leak of core coolant water resulting in the release of approximately 2.5 million curies of radioactive gases, and approximately 15 curies of iodine-131.
11 Cardiovascular Increased risk of hypertension Increased risk heart disease Increased risk of stroke Endocrine Increase in ghrelin (appetite regulating hormone) Diabetes and impaired glucose tolerance Increased risk of obesity Increase in stress hormones (cortisol) Impaired immune system response Nervous system Memory and learning Increased risk of seizures Increase in pain (migraines) Mental Health Decreased neurotransmitters affecting mood irritability, depression, alcohol use, suicide Decreased quality of life
12 Stress
13 SLEEP DEPRIVATION AND INFLAMMATION Shlomo Yehuda, Benjamin Sredni, Rafi L. Carasso, et al. REM sleep deprivation in rats results in inflammation and interleukin-17 elevation. Journal of Interferon & Cytokine Research. June 2009, 29(7):
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16 SLEEP AND LUPUS
17 SLEEP SYMPTOMS AND LUPUS 90 SLE women, cross sectional study with questionnaires Perceived stress scale (PSS), Brief COPE, Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Beck Depression Inventory (BDI) and Self-rating Anxiety Scale (SAS) Insomnia symptoms, n=57, 66% Higher perceived stress scale (p<.001) Higher emotional-focused coping (p=0.001) Palagini L, Mauri M, Faraguana U et al. Insomnia symptoms, perceived stress and coping strategies in patients with systemic lupus erythematous. Lupus Aug; 25(9):
18 SLEEP SYMPTOMS AND LUPUS 129 patients SLE, cross sectional study 1 72% poor sleep quality 20-32% severe anxiety and depression 26% pain 37% fatigue 14 SLE, 11 control underwent polysomnography on 3 nights 2 MSLT, questionnaire, Beck Depression More interrupted sleep and arousals More daytime sleepiness Disease activity association with decrease in sleep insufficiency, delta sleep and fragmentation 1. Huang HC, Chou CT, Lin KC, et al.the relationship between, disability level, health promoting lifestyle, and quality of life in patients with systemic lupus erythematosus. J Nurs Res 2007; 1: Valencia-Flores M, Resendiz M, Castaño VA, et al. Objective and subjective sleep disturbances in patients with systemic lupus erythematosus. Arthritis Rheum 1999; 42:
19 SLEEP DISORDERS AND AUTOIMMUNE DISEASE 1411 patients with obstructive sleep apnea (OSA) higher risk of developing autoimmune diseases 1 Link between OSA and systemic inflammation Possible that OSA may initiate autoimmune responses in susceptible individuals 1. Kang JH, Lin HC. Obstructive sleep apnea and the risk of autoimmune diseases: a longitudinal population based study. Sleep Med 2012; 13:
20 Hsiao YH, Chen YT, Tseng CM, W, et al. Sleep disorders and increased risk of autoimmune diseases in individuals without sleep apnea. SLEEP2015;38(4):
21 SLEEP AND HEALTH: HOW AND WHY DO WE SLEEP?
22 ABOUT SLEEP We spend 1/3 of our lives asleep Sleep is an active process No organ or regulatory system shuts down Some brain activity increases during sleep Many parts of the brain are as active as awake periods Specific hormones increase during sleep Growth hormone Melatonin
23
24 CIRCADIAN RHYTHM
25 Sleep Homeostatic drive (Sleep Load) Wake Sleep Alertness level Circadian alerting signal 9 AM 3 PM 9 PM 3 AM 9 AM Time American Academy of Sleep Medicine
26 HOW MUCH SLEEP DO WE NEED? No magic number Most adults need hours to function well 10% require more or less sleep * Basal Sleep Need the amount of sleep our body needs on a regular basis for optimal performance * Sleep Debt accumulated sleep that is lost due to poor sleep habits, sickness, awakenings due to environmental factors or other causes sleep is a rich and still poorly understood phenomenon. -National Sleep Foundation
27 BENEFITS OF SLEEP No other activity delivers so many benefits with so little effort! Improves Memory Lengthens Life Curbs Inflammation Helps Control Weight Lowers Stress Helps Decrease Risk of Depression
28 SLEEP HYGIENE
29 WHAT IS SLEEP HYGIENE? Good habits to optimize sleep
30 1. You can cheat on the amount of sleep that you get. 1 hour less sleep won t affect me at all! What is Your SLEEP IQ? 2. Health problems have no relation to the amount of sleep one obtains. 3. Watching TV in my bedroom and working on my laptop helps me wind down and fall asleep. 4. Alcohol or wine helps me fall asleep faster.
31 MAINTAIN A REGULAR BEDTIME AND WAKE TIME
32 ESTABLISH A REGULAR BEDTIME ROUTINE
33 RELAX AND DE-STRESS!
34 LIMIT NAPS DURING THE DAY
35 CREATE A SLEEP FRIENDLY ENVIRONMENT No television, reading or radio in bedroom No pets in the bed Decrease cell phone use Consider heavier drapery to darken room
36 NO CLOCK WATCHING
37 LIMIT STIMULANTS BEFORE BEDTIME Things to limit too close to bedtime Caffeine Metabolized in 4-7hrs Alcohol Nicotine Large or spicy meals
38 EXERCISE REGULARLY 123 adults with SLE Fatigue and physical activity Greater daily and moderate/vigorous physical activity (10minutes) lower mean fatigue severity score (p=0.03 and p=0.007) Less pain (p=0.01) Light physical activity and moderate physical activity correlated with better physical function (p=0.04, p=0.006) Mahieu MA, Ahn GE, Chmiel JS et al. Fatigue, patient reported outcomes, and objective measurement of physical activity in systemic lupus erythematosus. Lupus Oct; 25(11):
39 WHICH PICTURE IS AN EXAMPLE OF GOOD SLEEP HYGIENE
40 IF YOU HAVE DIFFICULTY SLEEPING Sleep restriction limit time in bed 20 minute rule Sleep hygiene Use your bed only for sleep and sex Avoid watching the clock Limit naps
41 KEEP A SLEEP DIARY TO IDENTIFY YOUR SLEEP HABITS AND PATTERNS
42 SEEK HELP FROM A SLEEP SPECIALIST AND A SLEEP STUDY
43 1. You can cheat on the amount of sleep that you get. 1 hour less sleep won t affect me at all! What is Your SLEEP IQ? 2. Health problems have no relation to the amount of sleep one obtains. 3. Watching TV in my bedroom and working on my laptop helps me wind down and fall asleep. 4. Alcohol or wine helps me fall asleep faster.
44 SUMMARY: WHAT CAN YOU DO? Learn about sleep Understand how your sleep changes and observe your habits and experiences Apply healthy sleep practices to your sleep style so that you get sufficient quality sleep Talk to your doctor about your sleep and see a sleep specialist if you experience chronic difficulty sleeping and/or have symptoms of sleep disorders
45 QUESTIONS?
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