Introduction OPT has been shown to effectively treat sleep apnea in about 40% of patients (Colrain IM et al. Sleep Medicine 14; , 2013)
|
|
- Julian Booth
- 5 years ago
- Views:
Transcription
1 Oral Pressure Therapy for OSA Oral Pressure Therapy for OSA - Disclosures Richard J. Schwab, M.D. Professor of Medicine Division of Sleep Medicine Pulmonary, Allergy and Critical Care Division University of Pennsylvania Medical Center Philadelphia, Pennsylvania NIH grants - RO1/PPG (Obesity and OSA) Consultant: Apnicure - Winx TM device Foramis Medical Group Winx TM (OPT) Device A novel oral pressure therapy (OPT) system (Winx TM, ApniCure, Inc.) provides negative pressure to the oral cavity Introduction OPT has been shown to effectively treat sleep apnea in about 40% of patients (Colrain IM et al. Sleep Medicine 14; , 2013) Console Mouth Piece 1
2 AHI and ODI: Cohort (n=26) AHI by Severity: Analysis Cohort (n=63) Examining the Mechanism of Action of a New Device Using Oral Pressure Therapy for the Treatment of Obstructive Sleep Apnea Schwab et al, submitted to sleep (conditionally accepted) Winx TM Device Study Objectives and Design Objective of the study was to explore the mechanism of action of the OPT (oral pressure therapy) device Case series study of 15 responders (13 men, 2 women) and 4 nonresponders (3 men) with sleep apnea. In the responders the mean AHI was 38.5 ± 23.3 events/hour before the OPT device was applied and was reduced to 6.7 ± 5.0 events/hour with the OPT device All subjects underwent a MRI to examine the biomechanical changes associated with the OPT device 2
3 Hypotheses With the application of oral pressure therapy (OPT): Mean, minimum and maximum airway area in the retropalatal region would increase Retropalatal anterior-posterior and lateral airway dimensions would increase Retroglossal airway dimensions would not change 3-dimensional centroid of the soft palate and anterior segment of the tongue would move anteriorly and superiorly Demographic Information for OPT Subjects Characteristic s (n=15) s (n=4) Age, mean ± SD 58.1 ± ± BMI, mean ± SD 30.9 ± ± Male, N (%) 13 (87%) 3 (75%) AHI at Baseline, mean ± SD 38.5 ± ± AHI on Device, mean ± SD 6.7 ± ± AHI Change, mean ± SD ± ± *p-value from Fisher s exact test (for categorical variable) or Wilcoxon two-sample exact test (for continuous variables) comparing responders and non-responders p* Methods: OPT Application 3D Image Analysis Magnetic Resonance Imaging (1.5T) During wakefulness and supine Baseline Device, No Suction 20 inches H 2 O BASELINE WITH OPT 3
4 Results - Retropalatal Airway Change with OPT BASELINE WITH OPT % Change Between Baseline and Device with 20 inches H 2 O Minimum Airway Area: 116% Improvement (69 mm 2 Baseline mm 2 Device) Maximum Airway Area: 20% Improvement (290.8 mm 2 Baseline mm 2 Device) Yellow lines indicate minimum retropalatal airway (lateral dimension) at baseline Airway Percent Changes the Retropalatal Region for OPT Device s Average Retropalatal Airway Area Per Slice (mm 2 ) Retropalatal Maximum A/P Distance Retropalatal Maximum Cross- Retropalatal Maximum Lateral Retropalatal Minimum A/P Distance Retropalatal Minimum Cross- Retropalatal Minimum Lateral Percent Change ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± *Change calculated with respect to baseline; Change calculated with respect to OPT 0 ; pvalue from non-parametric signed rank test Airway Percent Changes the Retropalatal Region for OPT Device s and s Average Airway Area Per Slice (mm 2 ) Maximum A/P Maximum Cross- Percent Change ± ± ± ± ± ± ± ± ± Maximum Lateral Distance (mm ) 3.28 ± ± ± Minimum A/P Minimum Cross- Minimum Lateral 2.16 ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± *Change calculated with respect to baseline; Change calculated with respect to OPT 0 ; p-value from non-parametric Wilcoxon two-sample exact test, comparing changes in responders vs. nonresponders ± ± ± ± ± ± ± Airway Percent Changes the Retroglossal Region for OPT Device s Average Retroglossal Airway Area Per Slice (mm 2 ) Retroglossal Maximum A/P Distance Retroglossal Maximum Cross- Retroglossal Maximum Lateral Retroglossal Minimum A/P Distance Retroglossal Minimum Cross- Retroglossal Minimum Lateral Distance (MM) Percent Change ± ± ± ± ± ± ± ± ± ± > ± ± ± ± ± ± ± ± ± ± ± *Change calculated with respect to baseline; Change calculated with respect to OPT 0 ; p-value from non-parametric signed rank test 4
5 Airway Percent Changes the Retroglossal Region for OPT Device s and s Average Airway Area Per Slice (mm 2 ) Maximum A/P Maximum Cross- Maximum Lateral Minimum A/P ± ± ± ± ± Percent Change Mean±SD Mean±SD Mean±SD ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± ± Results - Soft Tissue Effect with OPT Anterior Tongue Baseline Treatment Oral pressure therapy (OPT) treatment moved the 3-dimensional centroid of the soft palate anteriorly 12.9 ± 4.1 mm and superiorly 10.0 ± 3.6 mm Oral pressure therapy (OPT) treatment moved the centroid of the anterior segment of the tongue forward, towards the teeth, 7.8 ± 3.3 mm Minimum Cross ± ± ± ± ± ± Minimum Lateral ± ± ± ± ± ± *Change calculated with respect to baseline; Change calculated with respect to OPT 0 ; p-value from nonparametric Wilcoxon two-sample exact test, comparing changes in responders vs. non-responders Anterior Tongue Changes in the 3 Dimensional Centroid of the Anterior Quadrant of the Tongue and 3 Dimensional Centroid of the for OPT Device s Difference Changes in the 3 Dimensional Centroid of the Anterior Quadrant of the Tongue and 3 Dimensional Centroid of the for OPT Device s and s Difference Section: Anterior ± ± ± Section: Anterior ± ± ± ± ± ± Section: Superior ± ± ± Section: Superior ± ± ± ± ± ± : Anterior ± ± ± : Anterior ± ± ± ± ± ± : Superior Displacement 8.95 ± ± ± : Superior 8.95 ± ± ± ± ± ± *Change calculated with respect to baseline; Change calculated with respect to OPT 0 ; p-value from non-parametric signed rank test *Change calculated with respect to baseline; Change calculated with respect to OPT 0 ; p-value from non-parametric Wilcoxon two-sample exact test, comparing changes in responders vs. non-responders 5
6 ment and Results Oral pressure therapy significantly increased the size of the retropalatal airway in both the lateral and anterior-posterior dimensions by moving the soft palate anteriorly and superiorly and the anterior-superior segment of the tongue forward, towards the teeth In the retropalatal region there were significant increases in the mean, maximum and minimum cross-sectional areas with the OPT device However, in the retroglossal region airway caliber decreased with the OPT device Conclusions Oral pressure therapy (OPT), a novel treatment for sleep apnea, increases the size of the retropalatal airway by moving the soft palate anteriorly and superiorly and the anterior segment of the tongue forward, towards the teeth OPT increases airway caliber in both the anteriorposterior and lateral dimensions This treatment did not increase the size of the retroglossal airway Our data suggest that patients manifesting an enlarged soft palate or exhibiting retropalatal airway collapse would be ideal candidates for OPT therapy Next Generation Winx+ (adds a tongue retaining device Winx+ WINX 6
7 Feasibility Study of Winx+ Mouthpiece Subjects: 25 OSA patients naïve to Winx with AHI > 15 events/hour Protocol: Baseline full night PSG off therapy Full night PSG on Winx+ device followed by 4 nights use at home. Results of Feasibility Study #2: 25 Subjects to Date AHI Baseline Winx /25 (64%) had a > 50 reduction in AHI and final AHI < 20 16/25 (64%) had a > 50 reduction in AHI and final AHI < 15 13/25 (52%) had a > 50 reduction in AHI and final AHI < 10 Baseline, Winx, and Winx+ from the Sagittal View Baseline, Winx, and Winx+ from the Axial View (Retropalatal Airway) Baseline Winx Winx+ In this subject, the Winx device creates little to no change in the retropalatal region of the airway, while Winx+ creates more space behind the the soft palate increasing airway volume in the retropalatal region. The yellow arrows represent the Winx suction mechanism; the red arrow represents the tongue protrusion allowed for with Winx+. Baseline airway CSA = Winx airway CSA = Winx+ airway CSA = 95.2 mm mm mm 2 In this subject, the Winx device creates little to no change in the retropalatal region of the airway, while Winx+ creates more space behind the the soft palate increasing airway caliber in the retropalatal region. CSA = cross-sectional area 7
8 Baseline Oral Pressure Therapy for OSA Device Device Winx Winx+ Thank you for your attention! Any Questions? 8
Examining the Mechanism of Action of a New Device Using Oral Pressure Therapy for the Treatment of Obstructive Sleep Apnea
MECHANISM OF ACTION OF A NEW DEVICE USING ORAL PRESSURE THERAPY FOR OSA http://dx.doi.org/10.5665/sleep.3846 Examining the Mechanism of Action of a New Device Using Oral Pressure Therapy for the Treatment
More informationNew Perspectives on the Pathogenesis of OSA - Anatomic Perspective. New Perspectives on the Pathogenesis of OSA: Anatomic Perspective - Disclosures
New Perspectives on the Pathogenesis of OSA - Anatomic Perspective Richard J. Schwab, M.D. Professor of Medicine Interim Chief, Division of Sleep Medicine Medical Director, Penn Sleep Centers University
More informationComparative Effects of Two Oral Appliances on Upper Airway Structure in Obstructive Sleep Apnea
COMPARISON OF EFFECTS OF ORAL APPLIANCES ON THE AIRWAY IN OSA Comparative Effects of Two Oral Appliances on Upper Airway Structure in Obstructive Sleep Apnea Kate Sutherland, PhD 1,2 ; Sheryn A. Deane,
More informationSnoring And Sleep Apnea in the U.S. Definitions Apnea: Cessation of ventilation for > 10 seconds. Defining Severity of OSA
Snoring and Obstructive Sleep Apnea: Oral Appliance Therapy Management Midwest Society of Orthodontists October 16-17, 2009 Anthony J DiAngelis DMD, MPH Chief, Department of Dentistry, HCMC Professor,
More informationSleep Medicine. Paul Fredrickson, MD Director. Mayo Sleep Center Jacksonville, Florida.
Sleep Medicine Paul Fredrickson, MD Director Mayo Sleep Center Jacksonville, Florida Fredrickson.Paul@mayo.edu DISCLOSURES No relevant conflicts to report. Obstructive Sleep Apnea The most common sleep
More informationOBSTRUCTIVE SLEEP APNEA and WORK Treatment Update
OBSTRUCTIVE SLEEP APNEA and WORK Treatment Update David Claman, MD Professor of Medicine Director, UCSF Sleep Disorders Center 415-885-7886 Disclosures: None Chronic Sleep Deprivation (0 v 4 v 6 v 8 hrs)
More informationManagement of OSA. saurabh maji
Management of OSA saurabh maji INTRODUCTION Obstructive sleep apnea is a major public health problem Prevalence of OSAS in INDIA is 2.4% to 4.96% in men and 1% to 2 % in women In the rest of the world
More informationInfluence of upper airways section area on oxygen blood saturation level in patients with obesity and sleep apnea syndrome
Influence of upper airways section area on oxygen blood saturation level in patients with obesity and sleep apnea syndrome Poster No.: P-0028 Congress: ESCR 2015 Type: Scientific Poster Authors: E. Butorova,
More informationComparing Upper Airway Stimulation to Expansion Sphincter Pharyngoplasty: A Single University Experience
771395AORXXX10.1177/0003489418771395Annals of Otology, Rhinology & LaryngologyHuntley et al research-article2018 Original Article Comparing Upper Airway Stimulation to Expansion Sphincter Pharyngoplasty:
More informationAnesthesia Considerations for Dynamic Upper Airway Evaluation
Anesthesia Considerations for Dynamic Upper Airway Evaluation Mohamed Mahmoud MD Associate Professor of Anesthesia & Pediatrics Cincinnati Children s Hospital Medical Center Objectives Diagnosis of Sleep
More informationSnoring, obstructive sleep apnea (OSA), and upper. impact of basic research on tomorrow. Snoring Imaging* Could Bernoulli Explain It All?
impact of basic research on tomorrow Snoring Imaging* Could Bernoulli Explain It All? Igor Fajdiga, MD, PhD Study objectives: To identify upper airway changes in snoring using CT scanning, to clarify the
More informationSnoring and Obstructive Sleep Apnea: Patient s Guide to Minimally Invasive Treatments Chapter 2
Snoring and Obstructive Sleep Apnea: Patient s Guide to Minimally Invasive Treatments Chapter 2 CAUSES OF SNORING AND SLEEP APNEA We inhale air through our nose and mouth. From the nostrils, air flows
More informationIncreased Tongue Space. Option 1: Short Hook Single Point Midline Adjustment. turns the dsm world upside down! DDS TO MD COMMUNICATION
Insider MAGAZINE DENTAL SLEEP MEDICINE MARCH 2016 Issue 10 the new dreamtap Greater Adjustment Range Increased Tongue Space Custom-formed Soft Liners Superior Retention Option 1: Short Hook Single Point
More informationMorphological variations of soft palate and influence of age on it: A digital cephalometric study
Original Research Article Morphological variations of soft palate and influence of age on it: A digital cephalometric study C. Vani 1*, T. Vinila Lakshmi 2, V. Dheeraj Roy 3 1 Professor, 2 Post graduate
More informationCone-beam CT analysis of patients with obstructive sleep apnea compared to normal controls
Imaging Science in Dentistry 2016; 46: 9-16 http://dx.doi.org/10.5624/isd.2016.46.1.9 Cone-beam CT analysis of patients with obstructive sleep apnea compared to normal controls Allison Buchanan 1, *, Ruben
More informationSurgical Options for the Successful Treatment of Obstructive Sleep Apnea
Surgical Options for the Successful Treatment of Obstructive Sleep Apnea Benjamin J. Teitelbaum, MD, FACS Otolaryngology Head and Neck Surgery Saint Agnes Medical Center Fresno, California Terms Apnea
More informationClinical Papers. MRI s courtesy of Upper Airway Effects of Two Oral Appliances Sutherland et al
Clinical Papers MRI s courtesy of Upper Airway Effects of Two Oral Appliances Sutherland et al Development Design MK 2 2005 First molded TSD 2.6mm silicone wall thickness PLEASE NOTE: This version of the
More informationAnalysis of pharynx MRI in stroke patients with obstructive sleep apnea.
Research Article http://www.alliedacademies.org/allied-journal-of-medical-research/ Analysis of pharynx MRI in stroke patients with obstructive sleep apnea. Lixia Zhang 1#, Qi Wu 2#, Qian Zhung 3, Gan
More informationEffect of Three Different Mandibular Advancement Devices and Two Different Bite Techniques on the Resultant Sleep Metrics
Effect of Three Different Mandibular Advancement Devices and Two Different Bite Techniques on the Resultant Sleep Metrics Shamshudin (Sam) Kherani, DDS, FAGD, MICCMO Background It has been documented in
More informationEffect of two types of mandibular advancement splints on snoring and obstructive sleep apnoea
European Journal of Orthodontics 20 (1998) 293 297 1998 European Orthodontic Society Effect of two types of mandibular advancement splints on snoring and obstructive sleep apnoea J. Lamont*, D. R. Baldwin**,
More informationStep (2) Looked for correlations between baseline surrogates and postoperative AHI.
Development of the PSG PLUS PHYIOLOGY model Step (1) Picked possible surrogates of the physiological traits (See Table 1 in the main text). Step (2) Looked for correlations between baseline surrogates
More informationManagement Issues in Hypoglossal Stimulation for OSA. A Sleep Medicine view of surgery
Management Issues in Hypoglossal Stimulation for OSA Kingman P Strohl M.D. Professor of Medicine, Physiology & Biophysicis, and Oncology Center for sleep Disorders Reseach Case Western Reserve University,
More informationORIGINAL ARTICLE. for mild to moderate obstructive
ORIGINAL ARTICLE An Investigation of Upper Airway Changes Associated With Mandibular Advancement Device Using Sleep Videofluoroscopy in Patients With Obstructive Sleep Apnea Chul Hee Lee, MD, PhD; Jeong-Whun
More informationAirway and Airflow Characteristics In OSAS
Airway and Airflow Characteristics In OSAS 16 th Annual Advances in Diagnostics and Treatment of Sleep Apnea and Snoring February 12-13, 2010 San Francisco, CA Nelson B. Powell M.D., D.D.S. Adjunct Clinical
More informationNeuromuscular Stimulation for Sleep Apnea. Overview 1/24/2013. Disclosures. Midline Glossectomy. Palate + Hypopharyngeal Surgery: BMI
Neuromuscular Stimulation for Sleep Apnea Disclosures The following personal financial relationships with commercial interests relevant to this presentation: Eric J. Kezirian, MD, MPH Director, Division
More informationEdoardo Gronda UO cardiologia e Ricerca Dipartimento Cardiovascolare IRCCS MultiMedica
Convegno Pneumologia 2016 Milano 16-18 giugno 2016 Centro Congressi Palazzo delle Stelline Edoardo Gronda UO cardiologia e Ricerca Dipartimento Cardiovascolare IRCCS MultiMedica Central apnea 10 second
More informationObstructive sleep apnoea (OSA) has been. Heritability of upper airway dimensions derived using acoustic pharyngometry
Eur Respir J 2008; 32: 1304 1308 DOI: 10.1183/09031936.00029808 CopyrightßERS Journals Ltd 2008 Heritability of upper airway dimensions derived using acoustic pharyngometry S.R. Patel*,#, J.M. Frame #,
More informationSleep Apnea & Stroke: A Dangerous Liaison. Devin Brown, M.D., M.S. Professor of Neurology Stroke Program University of Michigan
Sleep Apnea & Stroke: A Dangerous Liaison Devin Brown, M.D., M.S. Professor of Neurology Stroke Program University of Michigan Conflict of Interest Disclosures for Speakers x 1. I do not have any relationships
More informationHypoglossal Nerve Stimulator Surgery for treatment of OSA. Disclosures. Hypoglossal Nerve Stimulation 11/9/2016
Hypoglossal Nerve Stimulator Surgery for treatment of OSA olando Molina MD South Florida ENT Associates A Disclosures I do not have any relevant financial disclosures at this time. Hypoglossal Nerve Stimulation
More informationTreatment of Obstructive Sleep Apnea (OSA)
MP9239 Covered Service: Prior Authorization Required: Additional Information: Yes when meets criteria below Yes as shown below None Prevea360 Health Plan Medical Policy: 1.0 A continuous positive airway
More informationK Don Bigelow DDS PC DASBA
K Don Bigelow DDS PC DASBA Graduate Medical College of Virginia School of Dentistry Diplomate American Sleep and Breathing Academy AASM Dental Sleep Masters International Academy of Dental Sleep Utah Sleep
More informationInspire Therapy for Sleep Apnea
Inspire Therapy for Sleep Apnea Patient Guide Giving You the FREEDOM TO SLEEP Like Everyone Else Take Comfort. Inspire therapy can help. Inspire therapy is a breakthrough implantable treatment option for
More informationEffect of upper-airway stimulation for obstructive sleep apnoea on airway dimensions
ORIGINAL ARTICLE SLEEP Effect of upper-airway stimulation for obstructive sleep apnoea on airway dimensions Faiza Safiruddin 1, Olivier M. Vanderveken 2,3, Nico de Vries 1,2,3, Joachim T. Maurer 4, Kent
More informationUpper Airway Stimulation for Obstructive Sleep Apnea
Upper Airway Stimulation for Obstructive Sleep Apnea Background, Mechanism and Clinical Data Overview Seth Hollen RPSGT 21 May 2016 1 Conflicts of Interest Therapy Support Specialist, Inspire Medical Systems
More informationMicrosurgical Anatomy of the Terminal Hypoglossal Nerve Relevant for Neurostimulation in Obstructive Sleep Apnea.
Neuromodulation. 05 Dec;8(8):7-8. doi: 0./ner.347. Epub 05 Sep 6. Microsurgical Anatomy of the Terminal Hypoglossal Nerve Relevant for Neurostimulation in Obstructive Sleep Apnea. Bassiri Gharb B, Tadisina
More informationInspire. therapy for sleep apnea. Giving you the freedom to sleep like everyone else
Inspire therapy for sleep apnea Giving you the freedom to sleep like everyone else Take Comfort. Take Action. Inspire therapy can help. Here are some reasons people like you have chosen Inspire therapy
More informationUPDATES IN SLEEP APNEA:
UPDATES IN SLEEP APNEA: CPAP,CPAP COMPLIANCE, & ALTERNATIVES MICHELLE ZETOONY, DO, FCCP, FACOI BOARD CERTIFIED PULMONARY, CRITICAL CARE, SLEEP & INTERNAL MEDICINE CLEARWATER, FL DISCLOSURE I have no conflicts
More informationSleep Apnea in Women: How Is It Different?
Sleep Apnea in Women: How Is It Different? Grace Pien, MD, MSCE Division of Pulmonary and Critical Care Department of Medicine Johns Hopkins School of Medicine 16 February 2018 Outline Prevalence Clinical
More informationEmerging Nursing Roles in Collaborative Management of Sleep Disordered Breathing and Obstructive Sleep Apnoea
Emerging Nursing Roles in Collaborative Management of Sleep Disordered Breathing and Obstructive Sleep Apnoea Sigma Theta Tau International 28th International Nursing Research Congress 27-31 July 2017
More informationThe Herbst. Used in the Treatment of Snoring and Obstructive Sleep Apnea. Appliance. Herbst with Standard Hardware
The Herbst Appliance Used in the Treatment of Snoring and Obstructive Sleep Apnea Herbst with Standard Hardware Herbst with Telescopic Advancement Hardware The Herbst for Snoring and Obstructive Sleep
More informationA Winning Combination
The Physiologic Sleep Bite and the Micr0 2 Sleep Device A Winning Combination There is no doubt that using the best bite technique available will improve overall treatment success, but how important is
More informationTreating OSA? Don't Forget the Tongue
From: ENT Today, January 2008 Treating OSA? Don't Forget the Tongue by Pippa Wysong Although otolaryngologic surgeons commonly focus on the palate when treating patients with obstructive sleep apnea (OSA),
More informationWHAT ARE ANTI-SNORING APPLIANCES?
WHAT ARE ANTI-SNORING APPLIANCES? These intraoral nighttime appliances can treat snoring by acting directly on the cause by pushing the lower jaw forward. In fact, mandibular repositioning pushes tongue
More informationSleep Disordered Breathing
Sleep Disordered Breathing SDB SDB Is an Umbrella Term for Many Disorders characterized by a lack of drive to breathe Results n repetitive pauses in breathing with no effort Occurs for a minimum of 10
More informationInspire Therapy for Sleep Apnea
Inspire Therapy for Sleep Apnea Take Heart. If you have OSA, you re not alone. More than 18 million Americans are estimated to have Obstructive Sleep Apnea (OSA). OSA occurs when the tongue and other soft
More informationDid you know more than a million Australians suffer from severe sleep apnoea?
Did you know more than a million Australians suffer from severe sleep apnoea? Your comprehensive guide to curing sleep apnoea www.futuredental.com.au 1 Contents What is Obstructive Sleep Apnoea? 2 What
More informationIdentification of Craniofacial Risk Factors for Obstructive Sleep Apnea Using Three-
Identification of Craniofacial Risk Factors for Obstructive Sleep Apnea Using Three Dimensional MRI Luqi Chi, MD; FrancoisLouis Comyn, DMD; Nandita Mitra, PhD; Muredach P. Reilly, MD; Fei Wan, BS; Greg
More informationSKUP 3 : 6 and 24 Months Follow-up of Changes in Respiration and Sleepiness After Modified UPPP
The Laryngoscope VC 2017 The American Laryngological, Rhinological and Otological Society, Inc. SKUP 3 : 6 and 24 Months Follow-up of Changes in Respiration and Sleepiness After Modified UPPP Nanna Browaldh,
More informationYear in Review. Outline of Lecture
Year in Review Allan I. Pack, M.B.Ch.B., Ph.D. John Miclot Professor of Medicine Director, Center for Sleep and Circadian Neurobiology University of Pennsylvania Perelman School of Medicine Philadelphia,
More informationInternational Journal of Scientific & Engineering Research Volume 9, Issue 1, January ISSN
International Journal of Scientific & Engineering Research Volume 9, Issue 1, January-2018 342 The difference of sleep quality between 2-channel ambulatory monitor and diagnostic polysomnography Tengchin
More informationOBSTRUCTIVE SLEEP APNEA and WORK Treatment Update
OBSTRUCTIVE SLEEP APNEA and WORK Treatment Update David Claman, MD Professor of Medicine Director, UCSF Sleep Disorders Center 415-885-7886 Disclosres: None Chronic Sleep Deprivation (0 v 4 v 6 v 8 hrs)
More informationTranssubmental tongue-base suspension in treating patients with severe obstructive sleep apnoea after failed uvulopalatopharyngoplasty:
CORRESPONDENCE: OUR EXPERIENCE Transsubmental tongue-base suspension in treating patients with severe obstructive sleep apnoea after failed uvulopalatopharyngoplasty: Our Experience Huang, T.-W.,* Su,
More informationA First Line Treatment for Sleep Disordered Breathing
A First Line Treatment for Sleep Disordered Breathing Sleep Disordered Breathing Snoring & Obstructive Sleep Apnoea Snoring and Obstructive Sleep Apnoea (OSA) are caused by the airway narrowing or even
More informationMedicare C/D Medical Coverage Policy
Medicare C/D Medical Coverage Policy Surgical Treatment of Obstructive Sleep Apnea Origination: June 26, 2000 Review Date: January 18, 2017 Next Review January, 2019 DESCRIPTION OF PROCEDURE OR SERVICE
More informationJMSCR Vol 05 Issue 01 Page January 2017
www.jmscr.igmpublication.org Impact Factor 5.84 Index Copernicus Value: 83.27 ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: https://dx.doi.org/10.18535/jmscr/v5i1.161 Risk of Failure of Adenotonsillectomy
More informationThe value of stratified economic analysis in cohort-level models: A case study on interventions for obstructive sleep apnea
The value of stratified economic analysis in cohort-level models: A case study on interventions for obstructive sleep apnea BERNICE TSOI AND KAREN LEE CADTH Disclosure No actual or potential conflict of
More informationUpdate on Obstructive Sleep Apnea (OSA) With Oral Appliance Therapy (OAT) for the Health Care Professional
Update on Obstructive Sleep Apnea (OSA) With Oral Appliance Therapy (OAT) for the Health Care Professional By Dr. Steven E. Todd, DMD, MaCSD, ABOI/ID Introduction and Objectives Discuss the impact of OSA
More informationPrimary Snoring Evaluation and Treatment
Primary Snoring Evaluation and Treatment Andrew N. Goldberg, MD, MSCE Professor Department of Otolaryngology-Head and Neck Surgery University of California-San Francisco Disclosures Apnicure Stock holder
More informationSnoring. Forty-five percent of normal adults snore at least occasionally and 25
Snoring Insight into sleeping disorders and sleep apnea Forty-five percent of normal adults snore at least occasionally and 25 percent are habitual snorers. Problem snoring is more frequent in males and
More informationEXPLORE NEW POSSIBILITIES
EXPLORE NEW POSSIBILITIES TREATING SNORING AND SLEEP APNOEA HAS CHANGED FOREVER Introducing the Oventus O 2 Vent, a custom made, comfortable oral appliance with a unique airway design for the treatment
More informationTHN. Sleep Therapy Study. ImThera. Information for Participants. Caution: Investigational device. Limited by United States law to investigational use.
THN Sleep Therapy Study Information for Participants Caution: Investigational device. Limited by United States law to investigational use. ImThera Obstructive sleep apnea (OSA) is a very serious condition.
More informationWAKE UP AND TAKE SNORING SERIOUSLY. TAP SCREENING TM SNORING VS. OBSTRUCTIVE SLEEP APNEA FACTS TO SLEEP ON. tapintosleep.com
TAP SYSTEM TM AN INTRODUCTION TO MODERN SLEEP CARE. TAP METHOD TM CPAP DOES NOT FIT ALL. Just like people, no two sleep experiences are the same. For a From predictor appliance to custom solutions, the
More informationQUESTIONS FOR DELIBERATION
New England Comparative Effectiveness Public Advisory Council Public Meeting Hartford, Connecticut Diagnosis and Treatment of Obstructive Sleep Apnea in Adults December 6, 2012 UPDATED: November 28, 2012
More informationSleep disorder of the upper airway results from any
Original Article Role of Oral Appliances in the Management of Sleep Disorders Lt Col B Jayan *, Brig BNBM Prasad, SM, VSM +, Col RK Dhiman # Abstract Background: A study was undertaken with the aim to
More informationResearch Article Continuous Positive Airway Pressure Device Time to Procurement in a Disadvantaged Population
Sleep Disorders Volume 2015, Article ID 747906, 5 pages http://dx.doi.org/10.1155/2015/747906 Research Article Continuous Positive Airway Pressure Device Time to Procurement in a Disadvantaged Population
More informationUpper Airway Muscle Stimulation for Obstructive Sleep Apnea
Upper Airway Muscle Stimulation for Obstructive Sleep Apnea M. Safwan Badr, MD, MBA Chair, Department of Medicine, Wayne State University School of Medicine. Staff Physician, John D. Dingell VA Medical
More informationThis pamphlet has been designed as
This pamphlet has been designed as an educational resource for patients with Obstructive Sleep Apnea (OSA). The successful use of CPAP requires no further intervention; however, not every patient is able,
More informationEindhoven University of Technology MASTER. Extracting features to discriminate OSA and non-osa. Pei, W. Award date: Link to publication
Eindhoven University of Technology MASTER Extracting features to discriminate OSA and non-osa Pei, W. Award date: 2013 Link to publication Disclaimer This document contains a student thesis (bachelor's
More informationTherapy of Snoring and Obstructive Sleep Apnea Using the Velumount Palatal Device
Original Paper ORL 29;71:148 152 DOI: 1.1159/216842 Received: December 22, 28 Accepted after revision: March 2, 29 Published online: May 7, 29 Sleep Apnea Using the Velumount Palatal Device Kurt Tschopp
More informationWeb-Based Home Sleep Testing
Editorial Web-Based Home Sleep Testing Authors: Matthew Tarler, Ph.D., Sarah Weimer, Craig Frederick, Michael Papsidero M.D., Hani Kayyali Abstract: Study Objective: To assess the feasibility and accuracy
More information3. Lightweight The uniquely-designed mouthguard weighs approximately 35 grams dependent on the customised design.
Patient FAQs Here are answers to common questions about the Oventus O 2Vent TM. What is the difference between the Oventus O2Vent TM and other oral devices? Like all oral appliances that bring the jaw
More informationUpper Airway Fat Tissue Distribution in Subjects With Obstructive Sleep Apnea and Its Effect on Retropalatal Mechanical Loads
Upper Airway Fat Tissue Distribution in Subjects With Obstructive Sleep Apnea and Its Effect on Retropalatal Mechanical Loads Yanru Li MD, Na Lin MD, Jingying Ye MD PhD, Qinglin Chang MD, Demin Han MD
More informationA New, Clinically Proven Sleep Apnea Therapy for people unable to use CPAP.
A New, Clinically Proven Sleep Apnea Therapy for people unable to use CPAP. Take Heart. If You Have OSA, You re Not Alone. Like you, more than 18 million Americans are estimated to have Obstructive Sleep
More informationin China Shanghai Office Beijing Office (+86) (+86)
SLEEP Apnea in China Guide 2018-2019 Shanghai Office (+86) 21 2426 6400 Beijing Office (+86) 010 6464 0611 www.pacificprime.cn Follow us on WeChat t A comprehensive overview of sleep apnea Perhaps you
More informationTired of being tired?
Tired of being tired? Narval CC MRD ResMed.com/Narval Sleepiness and snoring are possible symptoms of sleep apnea. Did you know that one in every four adults has some form of sleep disordered-breathing
More informationIn-Patient Sleep Testing/Management Boaz Markewitz, MD
In-Patient Sleep Testing/Management Boaz Markewitz, MD Objectives: Discuss inpatient sleep programs and if they provide a benefit to patients and sleep centers Identify things needed to be considered when
More informationFor personal use only
ASX Release Oventus presentation for AGM of Thorney Technologies Ltd Brisbane, Australia 24 th November 2017: Oventus Medical Ltd (ASX: OVN) is pleased to release a copy of the presentation that Founder
More informationBruxism: Revisiting an Old Problem with New Questions and Unique Solutions
Jeff Rouse, DDS Txacad@aol.com 555 E. Basse #200 www.coredentistry.com San Antonio, TX 78209 210-828-3334 Bruxism: Revisiting an Old Problem with New Questions and Unique Solutions CORE Concept Wear and
More informationBrian Palmer, D.D.S, Kansas City, Missouri, USA. April, 2001
Brian Palmer, D.D.S, Kansas City, Missouri, USA A1 April, 2001 Disclaimer The information in this presentation is for basic information only and is not to be construed as a diagnosis or treatment for any
More informationObstructive Sleep Apnea
Obstructive Sleep Apnea Introduction Obstructive sleep apnea is an interruption in breathing during sleep. It is caused by throat and tongue muscles collapsing and relaxing. This blocks, or obstructs,
More informationCAN SOFT TISSUES STRUCTURES DIFFERENTIATE BETWEEN DYSPLASIA AND CAM-FAI OF THE HIP?
CAN SOFT TISSUES STRUCTURES DIFFERENTIATE BETWEEN DYSPLASIA AND CAM-FAI OF THE HIP? A Le Bouthillier, KS Rakhra 1, PE Beaulé 2, RCB Foster 1 1 Department of Medical Imaging 2 Division of Orthopaedic Surgery
More informationThe Mandibular Advancement Device and Patient Selection in the Treatment of Obstructive Sleep Apnea
ORIGINAL ARTICLE The Mandibular Advancement Device and Patient Selection in the Treatment of Obstructive Sleep Apnea Chul Hee Lee, MD; Ji-Hun Mo, MD; Ik-Joon Choi, MD; Hyun Jong Lee, MD; Beom Seok Seo,
More informationInvestigation of positional and non-positional OSA: impact. on outcomes in patients treated with mandibular
Investigation of positional and non-positional OSA: impact on outcomes in patients treated with mandibular advancement devices Short title: Oral Appliances in positional and non-positional OSA JIN WOO
More informationChange of Obstruction Site by Modified Jaw Thrust Maneuver in Obstructive Sleep Apnea Patients
ORIGINAL ARTICLE pissn 2093-9175 / eissn 2233-8853 Sleep Med Res 2014;5(2):49-53 Change of Obstruction Site by Modified Jaw Thrust Maneuver in Obstructive Sleep Apnea Patients Soo-Kweon Koo, MD, PhD, Hyoung-Ju
More information11/19/2012 ก! " Varies 5-86% in men 2-57% in women. Thailand 26.4% (Neruntarut et al, Sleep Breath (2011) 15: )
Snoring ก Respiratory sound generated in the upper airway during sleep that typically occurs during inspiration but may occur during expiration ICSD-2, 2005..... ก ก! Prevalence of snoring Varies 5-86%
More informationObstructive Sleep Apnea in Truck Drivers
Rocky Mountain Academy of Occupational and Environmental Medicine Denver, Colorado February 6, 2010 Obstructive Sleep Apnea in Truck Drivers Philip D. Parks, MD, MPH, MOccH Medical Director, Lifespan Health
More informationA Matter of Life and Breath
SSpecial P EReport: C I AA Matter L RofELifePandOBreath RT A Matter of Life and Breath By Paul R. White, D.D.S. 804.715.1998 www.smilerichmond.com 804.715.1998 www.smilerichmond.com 1 Not to be overly
More informationSLEEP APNEA. Multimedia Health Education. Disclaimer
Disclaimer This movie is an educational resource only and should not be used to manage your health. All decisions about the management of Sleep Apnea must be made in conjunction with your Physician or
More informationBTS sleep Course. Module 10 Therapies I: Mechanical Intervention Devices (Prepared by Debby Nicoll and Debbie Smith)
BTS sleep Course Module 10 Therapies I: Mechanical Intervention Devices (Prepared by Debby Nicoll and Debbie Smith) S1: Overview of OSA Definition History Prevalence Pathophysiology Causes Consequences
More informationUpdate on Sleep Apnea Diagnosis and Treatment
Update on Sleep Apnea Diagnosis and Treatment Damien Stevens MD Pulmonary/Critical Care/Sleep Medicine Medical Director KU Medical Center Sleep Laboratory Objectives Discuss physiology of sleep and obstructive
More informationObstructive Sleep Apnea Treatment Services
Medical Coverage Policy Effective Date...06/15/2017 Next Review Date...06/15/2018 Coverage Policy Number... 0158 Obstructive Sleep Apnea Treatment Services Table of Contents Related Coverage Resources
More informationPrefabricated Oral Appliances for Obstructive Sleep Apnea
Medical Policy Manual Allied Health, Policy No. 36 Prefabricated Oral Appliances for Obstructive Sleep Apnea Next Review: May 2019 Last Review: April 2018 Effective: May 1, 2018 IMPORTANT REMINDER Medical
More informationAlexandria Workshop on
Alexandria Workshop on 1 Snoring & OSA Surgery Course Director: Yassin Bahgat MD Claudio Vicini MD Course Board: Filippo Montevecchi MD Pietro Canzi MD Snoring & Obstructive ti Sleep Apnea The basic information
More informationA Deadly Combination: Central Sleep Apnea & Heart Failure
A Deadly Combination: Central Sleep Apnea & Heart Failure Sanjaya Gupta, MD FACC FHRS Ohio State University Symposium May 10 th, 2018 Disclosures Boston Scientific: fellowship support, speaking honoraria
More informationCause and Prevention of OSA. Principles involved in OSA Hypothesis Prevention
Cause and Prevention of OSA Principles involved in OSA Hypothesis Prevention D1 Principles involved in airway collapse Vacuum Gravity Venturi principle Bernoulli principle D2 Vacuum D3 A vacuum can create
More informationVENT MONO INSTRUCTIONS FOR USE THE O 2 INTENDED USE
THE O 2 VENT MONO INSTRUCTIONS FOR USE INTENDED USE The Oventus O 2 Vent Mono is a removable medical device that is fitted in the patient s mouth and is intended to reduce or alleviate snoring and obstructive
More informationpromed Surgical Gowns Sterile Oropharyngeal Airway Guedels Solution
promed Surgical Gowns Sterile Oropharyngeal Airway Guedels Solution What s behind the brand? promed is an established brand that has been in the Australian market for more than 40 years Product categories
More informationPediatric Obstructive Sleep apnea An update What else is there to know?
Pediatric Obstructive Sleep apnea An update What else is there to know? Garani S. Nadaraja, MD, FAAP Medical Director BCH-Oakland Clinical Assistant Professor Division of Pediatric Otolaryngology UCSF
More informationPrecision Sleep Medicine
Precision Sleep Medicine Picking Winners Improves Outcomes and Avoids Side-Effects North American Dental Sleep Medicine Conference February 17-18, 2017 Clearwater Beach, FL John E. Remmers, MD Conflict
More information