Public Case Detail. Case Number : Reaction : Medicine details : Cases Count: 15. Gender : Weight (kg) : 36Y. Hospitalisation : Age :

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1 Case Number : /8/27 M 36Y Unknown Urticaria Reason : Tablet 4 Milligram 2 times Oral CITALOPRAM HYDROBROMIDE (Other drug) Reason : 4 Milligram Oral PUTRAN2 Page 1 of 18

2 Case Number : M 3/1/27 9/4/1937 Unknown Dscharge summary from psychatric hospital-final diagnoses-chronic delirium secondary to drug and medical causes. No indication of depression. Disorientation Aggression Agitation Confusional state Delirium Oedema Paranoia Psychotic disorder Disoriented, psychotic paranoia, agitated depression. Became delirious. Reported that he had attacked one of the nurses who was tyrying to restrain him. Oedema. Ceased Panadeine forte. Prescribed Zyprexa. Taken off Zyprexa and Edronax. Put on Risperidone. Had a minder in lock up situation for a week. Taken off Imovane and Risperidone. Given Endone. Taken off Mirtazapine. Tablet 12 Milligram Daily Oral IMOVANE (Suspected) Reason : Specific disorders of sleep Tablet 7.5 Milligram Daily Oral PUTRAN2 Page 2 of 18

3 PANADEINE FORTE (Suspected) Reason : Pain 1 Dose Unspec Daily ASPIRIN (Other drug) Reason : DILATREND (Other drug) Reason : NOVORAPID (Other drug) Reason : PANTOPRAZOLE (Other drug) Reason : PROTAPHANE (Other drug) Reason : PUTRAN2 Page 3 of 18

4 Case Number : /1/27 1/6/27 Not yet recovered F 74 52Y Hepatitis Incapacity/disability suspected drug induced hepatitis Hypertension Incapacity/disability Visual impairment Incapacity/disability Tablet 4 Milligram 2 times Oral Batch : Started : 1/3/25 Stopped : Lexapro (Suspected) Tablet 3 Milligram 1 time Oral Batch : Started : 3/6/26 Stopped : PUTRAN2 Page 4 of 18

5 Case Number : F 13/11/ /1/26 26/6/197 Not yet recovered is a seq of Nausea I am currently treated each symptom experiencing severe constipation despite eating fibre rich food etc. I also experience headaches over my left eye and still suffer from numbness around my left eye socket. I occasionally get the same tightness in my chest. I am now so loath to return to a doctor about these issues because of my experience late last year and early this year. Just last night I researched on the internet whether or not the Edronax could account for my range of symptoms and discovered that indeed it could! This is why I am now reporting all of them to this website. It's been over a year since I increased the dosage from 8mg to 12mg and it's been within that timeframe that I've experienced all of these symptoms. Chest pain Constipation Dizziness Headache Hypoaesthesia Hypotension Liver tenderness Lymphadenopathy Palpitations Syncope Vomiting Weight decreased PUTRAN2 Page 5 of 18

6 Tablet 4 Milligram 3 times Oral Batch : D832A Started : 6/1/26 Stopped : Laboratory Investigations : Type Range Date Tested Result Details Other data Ordered blood tests and CT scans of chest, abdomen and pelvis, these all came back negative for a cancer recurrence. Was tested for TB and some types of infectous diseases. These were also negative. Magnetic Resonance Imaging MRI of brain to check that there was no recurrence of breast cancer and still every test all came negative. PUTRAN2 Page 6 of 18

7 Case Number : /1/28 M 67Y Recovered Causality probable Dysuria Urinary retention 1.5 Dose Unspec Daily Oral PUTRAN2 Page 7 of 18

8 Case Number : M 29/2/28 68 Required a visit to the doctor 19/11/27 2/1/198 11/2/28 Recovered Penile discharge Penile discharge started after increasing from 8mg to 1mg Reboxetine. Reduce dose REBOXETINE MESYLATE (Suspected) 1 Milligram Daily Batch : Started : 18/11/27 Stopped : 11/2/28 PUTRAN2 Page 8 of 18

9 Case Number : M 2/4/28 99u Unknown Weight decreased weight loss, fall, increased Sudafed. blood pressure, erectile dysfunction, sinus congestion, appetite loss, pulse increased, mood swings, hot flushes, sweating, nausea, vomiting, fatigue, dizziness, chills, itching. Anorexia Blood pressure increased Chills Dizziness Erectile dysfunction Fatigue Heart rate increased Hot flush Hyperhidrosis Mood swings Nausea Pruritus Sinus congestion Syncope Vomiting PUTRAN2 Page 9 of 18

10 Case Number : M 29/4/28 99u Not yet recovered Dose of Efexor XR was not decreased gradually before commencing Edronax. Suicidal ideation Switched from Efexor XR to Edronax. Experienced suicidal thoughts, Edronax ceased and Xanax commenced until he is able to see his doctor again. aggression toward his wife and dizzy spells. Aggression Dizziness Reason : 8 Milligram Daily Batch : Started : 15/4/28 Stopped : EFEXOR-XR (Suspected) Reason : 15 Milligram Daily 15/4/28 PUTRAN2 Page 1 of 18

11 Case Number : M 6/6/28 31/5/28 15/1/1939 Recovered Dry mouth Anxiety Balance disorder Confusional state Dizziness Hyponatraemia Dry mouth, confusion, increased anxiety, dizziness, increasing problems with balance, hyponatraemia (111mmol/L) Reason : Tablet 8 Milligram 2 times Oral Batch : F65B Started : 15/5/28 Stopped : 31/5/28 CALTRATE (Other drug) Reason : Tablet 6 Milligram Daily Oral COLOXYL WITH SENNA (Other drug) Reason : As necessary NEXIUM (Other drug) Reason : Tablet 2 Milligram Daily Oral PANAMAX (Other drug) Reason : Cessation of Edronax and sodium replacement with IV isotonic saline PUTRAN2 Page 11 of 18

12 Laboratory Investigations : Type Range Date Tested Result Details Sodium 31/5/ sodium 128mmol/L on at 55 follwoing replacement with isotonic saline. Sodium 1/6/ sodium 128mmol/L on at 55 follwoing replacement with isotonic saline. PUTRAN2 Page 12 of 18

13 Case Number : F 2/6/28 Treated in outpatient department only. 23/4/28 16/3/1976 Not yet recovered Urinary retention Urinary retention Prazosin, IDC REBOXETINE MESYLATE (Suspected) 8 Milligram Daily Oral 23/4/28 ALPRAZOLAM (Other drug) Reason : 2 Milligram Daily OXYNORM (Other drug) Reason : 3 Milligram Daily PARACETAMOL (Other drug) Reason : 5 Milligram As necessary SALAZOPYRIN (Other drug) Reason : 2 Gram Daily SEROQUEL (Other drug) Reason : 2 Milligram Daily Zolpidem tartrate (Other drug) Reason : 12.5 Milligram Daily PUTRAN2 Page 13 of 18

14 Case Number : /6/28 Required a visit to the doctor 21/5/28 16/6/28 Recovered F 45 2/2/1958 Was on Edronax 4mg/daily and was fine, problems when dose increased. Angioedema Angioedema Tablet 6 Milligram Daily Oral Batch : Started : 21/5/28 Stopped : 3/5/28 LIPITOR (Other drug) Reason : Tablet 2 Milligram Daily Oral Batch : Started : L TERM Stopped : LOSEC (Other drug) Reason : 2 Milligram Daily Batch : Started : L TERM Stopped : PUTRAN2 Page 14 of 18

15 Case Number : M 28/7/28 99u 22/9/27 Recovered Stevens-Johnson syndrome Stevens-Johnson like Drug withdrawn reaction Erythema multiforme Urticaria papular Tablet 16 Milligram Daily Oral Batch : Started : 6/9/27 Stopped : 23/9/27 Escitalopram (Other drug) Reason : 1 Milligram Oral Batch : Started : 9/8/27 Stopped : PUTRAN2 Page 15 of 18

16 Case Number : F 24/9/28 1/9/1951 Causality probable Recovered Female sexual arousal Persistent genital arousal Edronax was discontinued. disorder syndrome 4 Milligram Daily Oral Batch : Started : 15/9/27 Stopped : 1/8/28 EPILIM (Other drug) Reason : Lexapro (Other drug) Reason : PUTRAN2 Page 16 of 18

17 Case Number : M 25/9/28 31/12/1949 Causality probable Recovered Urinary retention Urinary Retention after increasing dose from 2mg daily to 4 mg daily. Edronax ceased. Tablet 4 Milligram Daily Oral Batch : Started : 31/7/28 Stopped : 6/8/28 AVAPRO (Other drug) Reason : Lexapro (Other drug) Reason : MEGAFOL (Other drug) Reason : PARIET (Other drug) Reason : PUTRAN2 Page 17 of 18

18 Case Number : F 28/1/29 Required a visit to the doctor 3/12/28 4/8/1922 Not yet recovered Lethargy Lethargy, muscle Ceased medication weakness, abdominal pain. Abdominal pain Myalgia Tablet 8 Milligram Daily Oral Batch : Started : 28/11/28 Stopped : 8/12/28 COVERSYL (Other drug) Reason : INSULIN NOS (Other drug) Reason : METFORMIN HYDROCHLORIDE (Other drug) Reason : Selection Parameters : Date Range: 1/8/27 To 31/1/29 Unclear causality excluded GM medicines Only Medicine Names: EDRONAX, REBOXETINE MESYLATE PUTRAN2 Page 18 of 18

Public Case Detail. Preferred Term Severity Report Description Treatment Suicidal ideation Suicidal thoughts. Ceased Cymbalta

Public Case Detail. Preferred Term Severity Report Description Treatment Suicidal ideation Suicidal thoughts. Ceased Cymbalta Case Number : 242267 25/6/28 28/5/28 Unknown M 25Y Suicidal ideation Suicidal thoughts. Ceased Cymbalta Cymbalta (Suspected) Capsule 6 Milligram Daily Oral Batch : Started : 23/5/28 Stopped : 29/5/28 PUTRAN2

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