RAAT Rapid Access Model of Care in HCV
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1 RAAT Rapid Access Model of Care in HCV Marrianne Black CN Cheryl Sendall CNC Dr Caroline Tallis/Dr Rebecca Ryan Elizabeth Peat/Courtney Balk/Mirjana Palezevic AO Special thanks for the support and input of Professor Gerald Holtmann and Dr Katherine Stuart.
2 What is RAAT? Not this:
3 It is: Rapid Access to Assessment and Treatment. An Innovative Model of Care.
4 Epidemiology in Queensland Second highest number of patients with HCV to NSW new cases reported per year. Approximately 45,000 HCV infected patients in Queensland. PAH has highest incidence of newly reported cases in the state.
5 Background The burden of HCV related complications will continue to rise over the next 3 decades. There will be a significant percentage of HCV related cirrhosis, many with decompensated liver disease and HCC. The current level of burden in Australia of untreated HCV in Australia is estimated at: 9474 estimated cases of cirrhosis cases of liver failure cases of hepatocellular carcinoma 873 liver transplants. (
6 Burden Projected Prevalence of Chronic HCV, Cirrhosis, and Complications Projected Number of Patients With Decompensated Cirrhosis and Hepatocellular Carcinoma 160, , ,000 Hepatocellular Carcinoma (HCC) Decompensated Cirrhosis Number of Cases 100,000 80,000 60,000 40,000 20, Year Davis GL, et al. Gastroenterology. 2010;138(2): e516.
7 Why did we consider this new model of care? KEY POINT Demand for liver outpatient services far exceeded capacity ISSUES At the time the number of patients on the waiting list = 1309 Waiting times far exceeded the recommended and acceptable timeframes. Local population much undiagnosed chronic liver disease Immigrant population Also a Primary health care issue Future demand will only increase further with current calculations Growth of cases of chronic liver disease Increased growth of hepatocellular carcinoma cases Early and late stage presentation
8 Waiting times as at January Cat 1 Number 44 Waiting time 11 weeks Cat 2 Number 481 Waiting time 26 months Cat 3 Number 722 (most of which are referred with HCV) Waiting time 6 years, 5 months
9 Potential Risks Adverse Events: progression disease on waiting list Image of our waiting list: nationally and internationally Potential cost saving longer term Impact on Hospital stays: CLD management, HCC management longer term Let alone impact on QALY for the patient.
10 Why did we establish this new model of care? RAAT was conceived as a component of the FibroScan project. Following consideration of all the factors already outlined and the potential adverse effects to our patients, this innovative model of care was established.
11 In the beginning: The initial plan: To review and rationalise the Long Wait Category 3 Hepatology Outpatient List. To review those patients with viral hepatitis who would be suitable for treatment/trials. To screen Category 3 patients for CLD (chronic liver disease).
12 In the Beginning: Clinical Audit: 890 charts reviewed. Referrals placed on waiting list from 10/8/2005 to 30/6/2013.
13
14 Clinical Audit Assessment of referrals: Suitable for treatment -> RAAT clinic Suitable for trials -> RAAT clinic -> refer to trials. Stay on waiting list for now (non- viral, or not suitable for RAAT)
15 Findings from clinical audit 50 Patients with Hepatitis B. These patients were deemed a priority for RAAT assessment. 523 Patients with Hepatitis C 301 Patients to remain on waiting list as not suitable for RAAT clinic. 2 patient deaths whilst waiting were identified.
16 What we needed Increase Staffing all levels Administrative Nursing, include specialist nursing Medical Infra - structure Consulting rooms already available Laboratory resources available Radiology resources available
17 Proposed Structure 6 new cases per clinic session initially HBV and HCV. This was quickly increased to 10 new cases per clinic. Friday PM Gastroenterology OPD, Level 4: This clinic will also have access to the FibroScan
18 Patients with Hepatitis B Assessment in RAAT clinic. FibroScan undertaken, Ultrasound and Blood tests ordered. Follow up at Burke St and management plan implemented. Details also provided to Trials coordinators.
19 HCV patients seen in Friday PM RAAT clinic 209 patients (to 4/4/2014). 132 males FibroScan results: 18 patients with LSM >12kPa 57 patients with LSM >7kPa and <12kPa. Not all patients were treated due to either Being too sick to commence treatment. Significant co-morbidities. Personal preference to delay or not undergo treatment (Warehouse) 3 patients have been identified with HCC. 5 patients have been identified with de-compensated liver disease
20 Total number of patients seen in Friday PM RAAT clinic 29/6/2012 to 4/4/2014. Patients # booked #DNA # Seen # Resched # Cx Prev DNA Second DNA
21 Patients with HCV treated: 62 patients commenced treatment 8 patients accessed clinical trials 54 RAAT HCV treatment 8 cirrhosis
22 Results Thus Far ~ 90% RVR SVR 10 TPV 12 BOC 5
23 Previous Culture regarding HCV treatment. Warehouse. Trials Treatment. There is a shift away from warehousing patients.
24 Authors: Jennifer A Whitty, Caroline Tallis, Kim-Huong Nguyen, Paul A. Scuffham, Paul Crosland, Kaye Hewson, Rehka Pai Mangalore, Marrianne Black, Gerald Holtmann
25 Cost-effectiveness of RAAT.
26 Waiting times Where we started Cat 1 Number 44 Waiting time 11 weeks Cat 2 Number 481 Waiting time 26 months Cat 3 Number 722 Waiting time 6 years, 5 months AS AT 4/4/2014 Cat:1 Number 0 Waiting time 0 weeks Cat: 2 Number 233 Waiting time 7 months Cat:3 Number 257 Waiting time 2 years 3 months
27 Disclaimer To ensure equity all patients to 1/1/2012 have been seen in the RAAT clinic. All Category 3 patients with HCV deemed suitable for RAAT clinic have been seen from the waiting list with referrals received prior to June 2013.
28 Thank-you Special thanks to Cheryl Sendall for establishing the Treatment clinic. Elizabeth Peat, Courtney Balk and Mirjana Palezevic AO for the booking of the appointments. The Gastro OPD admin staff for their help with checking in these patients. And special mention to the team at Burke Street for their work in commencing some of the patients in this co-hort.
29 The next phase To date greater than 2100 patients have undergone a FibroScan procedure since the introduction of this new technology to our department. ARFI (acoustic radiation force impulse) has been trialled in the assessment of liver fibrosis in patients with liver disease. The Future: Supersonic Aixplorer is now undergoing trials within this department in the assessment of fibrosis for our patients.
30 And then. Perhaps we can stop the RAAT clinic and go to the CAT clinic. Completed Anti-viral Therapy.
31
32 Thank you.
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