LOGIQ S8 XDclear 2.0 Liver Procedures

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1 LOGIQ S8 XDclear 2.0 Liver Procedures See & quantify liver disease in a single exam Clinical Challenge Liver disease affects millions of people worldwide, and the number is growing. Clinicians need a cost-effective, highly reproducible way to help them identify high-risk patients, track disease progression quantifiably, and make informed decisions to optimize treatment efficacy and cost. GE Solution Combining key front-line modalities for diagnosing, staging and follow-up of liver disease, the Liver Package for the LOGIQ S8 XDclear 2.0 ultrasound system gives clinicians access to a comprehensive set of imaging and quantification capabilities. It includes the unique combination of leading-edge FibroScan powered by VCTE, CAP, and Shear Wave technologies designed for the consistency and reproducibility needed to assess patients across liver etiologies and throughout the care continuum. Diagnosis & Staging Treatment Planning & Guidance Liver Care Management

2 MANAGING LIVER CARE WITH ULTRASOUND The LOGIQ S8 XDclear 2.0 system offers a range of capabilities that make it well suited to managing patients with liver disease, particularly obese patients who may be difficult to assess with conventional ultrasound systems. Diagnosis & Staging 2D Shear Wave Elastography FibroScan VCTE and CAP Volume Navigation Treatment Planning & Guidance Ultrasound Specialty Probes Volume Navigation with 2D/3D GPS Needle Tracking Solutions 2D Shear Wave Elastography FibroScan VCTE and CAP FibroScan Specialty Probes FibroScan Non-invasive liver diagnostics The newly integrated FibroScan technology by Echosens is the reference non-imaging tool for the management of patients with chronic liver diseases. Its clinical utility is supported by over 1500 peer-reviewed publications and by internationally recognized guidelines, such as those published by the WHO, the EASL or the AASLD. FibroScan is designed to evaluate a predetermined 3 cm 3 volume of liver tissue with each examination. This standardization helps to reduce the length of the exam, while also helping to optimize test accuracy and consistency over time, irrespective of the operator or device used. FibroScan dual-function capability simultaneously provides two quantitative measurements to support clinicians across liver etiologies including hepatitis B (HBV), hepatitis C (HCV) and fatty liver diseases (NAFLD, NASH): Vibration-Controlled Transient Elastography (VCTE) measures liver stiffness (expressed in kpa) to quantify fibrosis and cirrhosis Controlled Attenuation Parameter (CAP) option measures the ultrasound attenuation (expressed in db/m) to quantify steatosis in the liver, specifically relevant in fatty liver diseases

3 INFORMATION ACROSS THE LIVER CARE CONTINUUM Diagnosis & Staging Treatment Planning & Guidance CEUS Contrast enhanced ultrasound enhances the clinician s ability to detect and characterize lesions. Parametric imaging and TIC are available for further quantification and assessment. 2D Shear Wave Elastography Enables non-invasive, quantitative assessment of tissue stiffness in a growing range of applications helping to expand clinical utility to more patients. FibroScan VCTE and CAP Clinically validated technology to support diagnosis and staging of chronic liver diseases, FibroScan simultaneously provides two quantitative measurements to support clinicians: liver stiffness (expressed in kpa) to stage liver fibrosis/cirrhosis and liver attenuation parameter (expressed in db/m) to stage liver steatosis. Volume Navigation Enables merging of real-time ultrasound with CT, MR, CBCT, or 3D ultrasound images to simplify the detection and counting of masses, lesions and nodules. Ultrasound Specialty Probes E-Series and XDclear probes are specifically designed for interventional, biopsy guidance and intraoperative scanning. CEUS Provides valuable clinical information for planning treatment protocols and confirming results of ablative treatment. Volume Navigation with 2D/3D GPS Helps visually track the probe position during a scan from different views, mark targets, plan treatments and procedures, and guide challenging biopsies with improved confidence and accuracy. Needle Tracking Solutions A re-usable sensor displays the exact position of the needle tip to enhance accuracy and simplify procedures. CEUS Provides information to evaluate suspected recurrence postablation, or identify new pathologies. 2D Shear Wave Elastography Useful in helping clinicians monitor liver fibrosis over time and assess changes in the patient s condition related to treatment efficacy and lifestyle decisions. FibroScan VCTE and CAP Clinically validated technology to support monitoring of chronic liver diseases, FibroScan is designed to evaluate a predetermined 3 cm 3 volume of liver tissue. It is supported by integrated Smart Tools to ensure consistent measurements over time, across patients and irrespective of the operator. This reliable tool is used to monitor liver treatment, track therapeutic response and follow-up disease progression. FibroScan Specialty Probes FibroScan s M+ and XL+ probes have been designed to provide a consistent measurement across patient s morphology. Dual image of Shear Wave using C1-6-D and FibroScan using M+ probe Shear Wave imaging with C1-6-D Liver Volume Navigation with C1-5-D CEUS of liver nodule using 9L-D Liver imaging with C1-6-D CEUS imaging of the liver with C1-6-D

4 SIMPLY AMAZING From Image Quality to Workflow to Economics S-Agile Acoustic Architecture This dedicated general imaging technology from GE Healthcare uses dynamic models of the human body, based on clinical data, to help clinicians acquire images on a broad spectrum of patients. The result is superb images with just a few keystrokes. Choice of high performance probes The system offers both E-Series and XDclear probes, designed to cover the entire liver care continuum and patient population. Advancements in acoustic engineering help increase penetration and deliver high definition resolution. Specialty probes are also available for interventional, biopsy guidance, and intraoperative scanning. Liver-specific workflow The LOGIQ S8 XDclear 2.0 system can be configured with side-by-side ultrasound and FibroScan capabilities to combine imaging, Shear Wave Elastography, and FibroScan elastography tools in a single exam. Ultrasound presets are designed specifically to accommodate a wide range of patient populations. Semi-automatic measurements in Shear Wave Elastography enable users to quickly and easily obtain quantifiable information. Improving liver care economics through non-invasive technology The availability of a cost-effective, non-in vasive test with quantified, reproducible results has the potential to change the economics of liver disease management. FibroScan VCTE and CAP have demon strated clinical and economical utility in more than 1500 peer-reviewed publications. Together, they help clinicians identify high-risk patients, diagnose and stage disease, and monitor disease progression. This can lead to early and informed decisions that optimize treatment efficacy and cost for millions of patients worldwide with chronic liver disease.

5 Imagination at work Product may not be available in all countries and regions. Contact a GE Healthcare Representative for more information. Data subject to change General Electric Company. GE, the GE Monogram, imagination at work, LOGIQ, XDclear and B-Flow are trademarks of General Electric Company. FibroScan technology has been developed by Echosens. FibroScan, VCTE and CAP are trademarks of Echosens ( The LOGIQ S8 is designed for compatibility with most commercially available ultrasound contrast agents. Availability of these agents is subject to government regulation and approval. Contrast imaging should be performed within the approved indications for use of the contrast agent used in the exam. Reproduction in any form is forbidden without prior written permission from GE. Nothing in this material should be used to diagnose or treat any disease or condition. Readers must consult a healthcare professional. March 2017 JB47687US

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