No. Title Page 1 PERANAN PROTEIN GOAT ZONA PELLUCIDA-3 (gzp3) SEBAGAI RESEPTOR FERTILISASI DAN POTENSINYA SEBAGAI KANDIDAT BAHAN IMUNOKONTRASEPSI

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2 Table of Contents No. Title Page 1 PERANAN PROTEIN GOAT ZONA PELLUCIDA-3 (gzp3) SEBAGAI RESEPTOR FERTILISASI DAN POTENSINYA SEBAGAI KANDIDAT BAHAN IMUNOKONTRASEPSI - 2 PERANAN PROLAKTIN SEBAGAI IMMUNOREGULATOR - 3 PENGARUH ASAM ASKORBAT TERHADAP KADAR IMUNOGLOBULIN A SEKRETORI PADA SALIVA - 4 Peran Fisiologis Sekresi Leptin sebagai Dasar Pencegahan Obesitas 18-23

3 Vol. 5 - No. 1 / TOC :, and page PERANAN PROLAKTIN SEBAGAI IMMUNOREGULATOR PERANAN PROLAKTIN SEBAGAI IMMUNOREGULATOR Abstract 1. Agustina Rahayu Magdalena --> 2. Paulus Liben --> Prolactin is neuroendocrine that is not only produced in anterior hypophyse but also on other several organ. Prolactin receptor in all of the body, include bone marrow, thymus, spleen, T-lymphosit, B-lymphosit and macrophage, play a role on immunity processes. In chronic inflammation, prolactin can reduce immunosupresif effect that caused by glucocorticoid and autoimun diseases. Prolactin increase T-lymphosit proliferation and seluler immunity. Prolactin in T-lymphosit increase IL-2 activities and IL-2 receptor. IL-2 receptor in T-lymphosit increase cytotoxin activities and IL-2 production and secretion. Prolactin also increase B-lymphosit proliferation and antibody production. Prolactin can increase monocyte differentiation and macrophage activities. Prolactin in NK cell can increase poliferation, cytotoxin activites, and also IFNï production and secretion. Those show that prolactin play an important role as immunoregulator Keyword : prolactin, immunoregulator,, Daftar Pustaka : 1. Ben Jonathan N, (1996). extrapituitary prolactin: distribution, regulation, functions and clinical aspects. Endorev 17(5) M Adary, (1996). Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endorev 19(3) feysot C Bole, (1998). Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endorev 19(3) V Goffin, (1996). Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endorev 19(3) A D Rey, (1996). Immune-neuro-endocrine interactions: facts and hypotheses. Endorev. 17(1) R W Steinmetz, (1996). extrapituitary prolactin: distribution, regulation, functions and clinical aspects. Endorev 17(5) D L Allen, (1996). extrapituitary prolactin: distribution, regulation, functions and clinical aspects. Endorev 17(5) J L Mershon, (1996). extrapituitary prolactin: distribution, regulation, functions and clinical aspects. Endorev 17(5) D O Freier, (1998). Review: prolactin receptor signal transduction in cells of the immune system. Endocrinology N Binart, (1996). Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endorev 19(3) P A Kelly, (1998). Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endorev 19(3) B Bouchard, (1999). Immune system development and function in porlactin receptor-deficient mice. Journal of 13. H O Besedovsky, (1996). Immune-neuro-endocrine interactions: facts and hypotheses. Endorev. 17(1) C J Ormandy, (1999). Immune system development and function in porlactin receptor-deficient mice. Journal of 15. J Di santo, (1999). Immune system development and function in porlactin receptor-deficient mice. Journal of 16. P A Kelly, (1999). Immune system development and function in porlactin receptor-deficient mice. Journal of 17. V Chesnokova, (2002). Minireview: neuro-immuno-endocrine modulation of the hypothalamic-pituitary-adrenal (HPA) axis by gp130 signaling molecules. Endocrinology 143(5) S Melmed, (2002). Minireview: neuro-immuno-endocrine modulation of the hypothalamic-pituitary-adrenal (HPA) axis by gp130 signaling molecules. Endocrinology 143(5) L C Chikanza, (1998). Review hypothalamic-pituitary mediated immunomodulation: arginine vasopressin is a neuroendocrine immune mediator. British journal of rheumatology A S Grossman, (1998). Review hypothalamic-pituitary mediated immunomodulation: arginine vasopressin is a neuroendocrine immune mediator. British journal of rheumatology C V Clevenger, (1998). Review: prolactin receptor signal transduction in cells of the immune system. Endocrinology

4 D O Freier, (1998). Review: prolactin receptor signal transduction in cells of the immune system. Endocrinology J B Kline, (1998). Review: prolactin receptor signal transduction in cells of the immune system. Endocrinology J B Kline, (1998). Review: prolactin receptor signal transduction in cells of the immune system. Endocrinology K Dohi, (2003). Exercise increases prolactin-receptor expression on human lyphocytes. Am J physiol W J Kraemer, (2003). Exercise increases prolactin-receptor expression on human lyphocytes. Am J physiol W J Kraemer, (2003). Exercise increases prolactin-receptor expression on human lyphocytes. Am J physiol A M Mastro, (2003). Exercise increases prolactin-receptor expression on human lyphocytes. Am J physiol K Dorshkind, (2000). The role of prolactin, growth hormone, insuli-like growth factor-1 and thyroid hormones in lymphocyte development dan function: insights from genetic models of hormone and hormone receptor deficiency. Endorev 21(3) N D Horseman, (2000). The role of prolactin, growth hormone, insuli-like growth factor-1 and thyroid hormones in lymphocyte development dan function: insights from genetic models of hormone and hormone receptor deficiency. Endorev 21(3) M E Freeman, (2000). Prolactin: structure, function, and regulation of secretion. Physiol Rev 80(4) B Kanyicska, (2000). Prolactin: structure, function, and regulation of secretion. Physiol Rev 80(4) A Lerant, (2000). Prolactin: structure, function, and regulation of secretion. Physiol Rev 80(4) G Nagy, (2000). Prolactin: structure, function, and regulation of secretion. Physiol Rev 80(4) W F Ganong, (2001). Review of medical physiology. 20th Ed. New York : McGraw-Hill 36. K Horiguchi, (2004). Prolactine gene expression in mouse spleen helper T cells. Endocrinology S Yagi, (2004). Prolactine gene expression in mouse spleen helper T cells. Endocrinology K Ono, (2004). Prolactine gene expression in mouse spleen helper T cells. Endocrinology Y Nishiura, (2004). Prolactine gene expression in mouse spleen helper T cells. Endocrinology M Tanaka, (2004). Prolactine gene expression in mouse spleen helper T cells. Endocrinology M Ishida, (2004). Prolactine gene expression in mouse spleen helper T cells. Endocrinology T Harigaya, (2004). Prolactine gene expression in mouse spleen helper T cells. Endocrinology N D Horseman, (1994). Transcriptional regulation by the helix bundle peptide hormones: growth hormone, prolactin and hematopoietic cytokines. Endorev 15(5) L Yu-lee, (1994). Transcriptional regulation by the helix bundle peptide hormones: growth hormone, prolactin and hematopoietic cytokines. Endorev 15(5) H Lodish, (2001). Cell-to-cell signaling: hormones and receptors in Molecular cell biology. 4th. ed.. New York : WH Freeman dan Co 46. K S Madden, (1995). Experimental basis for neural-immune interactions. Physiol Rev D L Felten, (1995). Experimental basis for neural-immune interactions. Physiol Rev M Maruyama, (2001). Prolactin-releasing peptide as novel stress mediator in the central nervous system. 49. H Matsumoto, (2001). Prolactin-releasing peptide as novel stress mediator in the central nervous system. 50. K Fyjiwara, (2001). Prolactin-releasing peptide as novel stress mediator in the central nervous system. 51. J Noguchi, (2001). Prolactin-releasing peptide as novel stress mediator in the central nervous system. 52. C Katada, (2001). Prolactin-releasing peptide as novel stress mediator in the central nervous system. Endocrinology 142(5) M Fujino, (2001). Prolactin-releasing peptide as novel stress mediator in the central nervous system. Endocrinology 142(5) K Inoue, (2001). Prolactin-releasing peptide as novel stress mediator in the central nervous system. Endocrinology 142(5) D G Remick, (1997). Interleukin-2: molecular and clinical aspects in Cytokines in health and disease. 2nd Ed. New York : Marcel dekker Inc 56. J S Friedland, (1997). Interleukin-2: molecular and clinical aspects in Cytokines in health and disease. 2nd Ed. New York : Marcel dekker Inc 57. I Roitt, (1993). Regulation of immune response in Immunology. 3rd Ed. Philadelphia :. Mosby 58. J Brostoff, (1993). Regulation of immune response in Immunology. 3rd Ed. Philadelphia :. Mosby 59. D Male, (1993). Regulation of immune response in Immunology. 3rd Ed. Philadelphia :. Mosby 60. W Savino, (2000). Neuroendocrine control of thymus physiology. Endorev 21(4) M Dardenne, (2000). Neuroendocrine control of thymus physiology. Endorev 21(4). -

5 Powered by TCPDF ( 62. Suryohudoyo P, (2000). Mekanisme molekuler aktifitas hormon dalam kapita selekta ilmu kedokteran molekuler. Jakarta : CV Infomedika 63. M O Thorner, (1998). The anterior pituitary in William textbokk of endocrinology. 9th Ed. Philadelphia : WB Saunders 64. M L Vance, (1998). The anterior pituitary in William textbokk of endocrinology. 9th Ed. Philadelphia : WB Saunders 65. E R Laws, (1998). The anterior pituitary in William textbokk of endocrinology. 9th Ed. Philadelphia : WB Saunders 66. E Horvath, (1998). The anterior pituitary in William textbokk of endocrinology. 9th Ed. Philadelphia : WB Saunders 67. K Kovacs, (1998). The anterior pituitary in William textbokk of endocrinology. 9th Ed. Philadelphia : WB Saunders 68. Y Ueta, (2003). Involvement of novel feeding-related peptides in neuroendocrine response to stress. Exp Biol Med 69. Y Ozaki, (2003). Involvement of novel feeding-related peptides in neuroendocrine response to stress. Exp Biol Med 70. J Saito, (2003). Involvement of novel feeding-related peptides in neuroendocrine response to stress. Exp Biol Med 71. T Onaka, (2003). Involvement of novel feeding-related peptides in neuroendocrine response to stress. Exp Biol Med 72. L Yu-lee, (2002). Prolactin modulation of immune and inflammatory responses. Endocrinology

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