Orbital decompression in Graves orbitopathy: state of the art and novel perspectives Baldeschi, L.

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1 UvA-DARE (Digital Academic Repository) Orbital decompression in Graves orbitopathy: state of the art and novel perspectives Baldeschi, L. Link to publication Citation for published version (APA): Baldeschi, L. (2011). Orbital decompression in Graves orbitopathy: state of the art and novel perspectives General rights It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. UvA-DARE is a service provided by the library of the University of Amsterdam ( Download date: 09 Sep 2018

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3 Lelio Baldeschi was born in Pisa, Italy, on 24 th March 1964, is married with Antonella and happy father of their little tiger, Giovanni. He qualified in Medicine cum laude at the University of Pisa and graduated in Ophthalmology cum laude at the University of Florence, before he sub-specialized in oculoplastic and orbital surgery first under the guide of Richard Collin and Geoffrey Rose at Moorfields Eye Hospital in London and then with Leo Koornneef at the Orbital Centre, University of Amsterdam. Afterwards he has been a Consultant surgeon to Orbital Centre, University of Amsterdam, where he trained in oculoplastic, lacrimal and orbital surgery residents in ophthalmology and nineteen international fellows, and had the opportunity to publish in the field of adnexal diseases. He has been member of the scientific advisory board, invited speaker and faculty member at a wide variety of international congresses, and courses, visiting professor to several European and North American universities, and had organised national and international congresses. Currently he is member of the Italian Society of Ophthalmology, European Society of Ophthalmic Plastic and Reconstructive Surgery, serve in the steering committee of the European Group on Graves Orbitopathy, and is the President of the Italian Society of Ophthalmic Plastic Surgery. Referee to: Ophthalmology American Journal of Ophthalmology European Journal of Ophthalmology British Journal of Ophthalmology Clinical Ophthalmology Orbit Ophthalmic Plastic and Reconstructive Surgery Expert review of clinical immunology Clinical Anatomy Clinical Medicine Radiation oncology Journal of endocrinological Investigation Thyroid Cochrane Eyes and Vision Group of the Cochrane Library 192

4 Thirty of 145 invited lectures 1. The Jack Crawford Oculoplastics Lecture : Graves Orbitopathy. Mount Sinai Hospital, University of Toronto,. Toronto, Canada, 9 December Treatment of orbital fractures. III International Congress of the Italian Society of Ophthalmology, Florence, Italy, May Surgical treatment of Graves orbitopathy. 36 th Congress of the Societat Catalana d Oftalmologia (Catalan Society of Ophthalmology), Barcelona, Spain, November Decompression surgery in Graves orbitopathy: status of the art and open issues. Full Member Winter Meeting of the European Society of Ophthalmic Plastic and Reconstructive Surgery (ESOPRS), Cortina d Ampezzo, Belluno, Italy, January 2006;. 5. Orbital rhabdomyosarcomas. Advanced in orbital diseases. World Congress of Ophthalmology, S. Paulo, Brazil, February Orbital myositis. Advanced in orbital diseases. World Congress of Ophthalmology, S. Paulo, Brazil, February Benign and malignant paediatric orbital tumours. XVI Congress of the Sociedad Española de Cirugía plástica Ocular y Orbitaria (Spanish Society of Ophthalmic Plastic and Orbital Surgery), Barcelona, Spain, June Fine needle aspiration cytology versus open sky biopsy in orbital oncology. XVI Congress of the Sociedad Española de Cirugía plástica Ocular y Orbitaria (Spanish Society of Ophthalmic Plastic and Orbital Surgery), Barcelona, Spain, June The hot orbit and complication of immunesuppression. Cursus: Immunosup- pressive Therapy in Adnexal and Ocular Surface Disorders. Indications, Protocols, Wanted and Unwanted Effects. Congress of the European Society of Ophthalmology (SOE) Vienna, Austria, 12 June Extraocular muscle changes in Dysthyroid Eye Disease. Symposium of the Academia Ophthalmologica Internationalis (AOI) for the congress of the European Society of Ophthalmology (SOE) Vienna, Austria, 9-12 June Featured guest lecture:functional and rehabilitative surgery for Graves orbitopathy. XV Annual congress of the Italian Society of Maxillo-Facial Surgery (SICMF), Bologna June Graves orbitopathy: treatment of tear film alterations and corneal exposure. XXV Congress of the European Society of Cataract and Refractive Surgeons (ESCR), Stockholm, Sweden 8-12 September The lateral orbital wall and its role in decompression surgery for dysthyroid eye disease. Symposium: Current developments in ophthalmic plastic and reconstructive surgery" 105 th Congress Deutschland Oogheelkundig Gezelschap (DOG) September 2007, Berlin, Germany. 14. New surgical approaches for orbital decompression surgery. Symposium: Update Graves orbitopathy: an interdisciplinary challange" 105 th Congress Deutschland Oogheelkundig Gezelschap (DOG) September 2007, Berlin, Germany 15. Dysthyroid orbitopathy: indications and results of surgical treatment. VII Congress of the Italian Society of MD Endocrinologists (AME) Bologna, Italy 2-4 Novembre

5 16. Mechanical, not endoscopic endonasal dacryocystorhinostomy. IX Word Congress of the International Society of Dacryology and Dry Eye (ISD&DE), Istanbul, Turkey, May Orbital Tumor management. Pre-meeting Institutional pre-meeting course: Eyelid course and orbital on eyelid diseases. and orbital 26 th annual disease meeting of the XXVI of the congress European of Society the European of Ophthalmic Society Plastic of Ophthalmic and Reconstructive Plastic Surgery and Reconstructive (ESOPRS), Lucerne, Surgery Switzerland (ESOPRS), Lucerne, 12 June Switzerland 12 June Ocular surface alterations and their treatment in Graves Graves orbitopathy. XXVI Congress of the European Society of Cataract and Refractive Surgeons (ESCRS), Berlin, Germany September Indications and techniques for orbital decompression in Graves Graves orbitopathy: new developments. Symposium of the European Society of Ophthalmology (SOE) within the American Academy of Ophthalmology (AAO): Update on orbital surgery. Atlanta, GA, Georgia, USA, USA, Novembre Novembre Surgical management of Graves Graves orbitopathy: active phase and rehabilitation. Symposium: Graves orbitopathy - actual management strategies. 17 th Congress of the European Society of Ophthalmology (SOE) Amsterdam, The Netherlands, June Endonasal dacryocystorhinostomy in modern lacrimal surgery. Symposium: Lacrimal surgery: how to deal with the watery patient. 17 th Congress of the European Society of Ophthalmology (SOE) Amsterdam, The Netherlands, June The treatment of eyelid retraction in Graves Graves orbitopathy and other diseases. XXVII Congress of the European Society of Cataract and Refractive Surgeons (ESCR), Barcelona, Spain September The EUGOGO experience. Word congress Pediatric Ophthalmology and Strabismus (WCPOS), Barcelona, Spain September Endonasal mechanical not endoscopic dacryocystorhinostomy. Symposium of the Section DOG- Ophthalmoplastic and Reconstructive Surgery: Recent development in Ophthalmic Plastic and Reconstructive Surgery. 107 th Congress Deutschland Oogheelkundig Gezelschap (DOG), Leipzig, Germany, September Bone orbital decompression. International Symposium on Graves Graves orbitopathy of the European Group on Graves Orbitopathy (EUGOGO), Amsterdam, the Netherlands, October Featured guest symposium: Graves orbitopathy: pathogenesis, clinical assessment, medical and surgical therapy. therapy. Philippines Academy of of Ophthalmology (PAO) annual meeting 2009, Cutting Edge Ophthalmology: The Best from Europe November 2009, Manila, Philippines. 27. Orbital surgery. Symposium on Graves Graves disease. World Congress of Ophthalmology, 5-9 June, Berlin, Germany. 28. Rehabilitative and functional decompressions. decompressions. Symposium of of the European Group on Graves Orbitopathy (EUGOGO), World Congress of Ophthalmology, 5-9 June, Berlin, Germany 29. Graves Graves ophthalmopathy: surgical management. management. Pre-meeting course: Current concepts in ophthalmic plastic surgery. 28 th annual meeting of the European Society of Ophthalmic Plastic and Reconstructive Surgery, 9-11 September 2010, Munich, Germany. 30. Featured speaker lecture: The The EUGOGO EUGOGO experience: experience: take home take messages home messages for the oculofacial for the oculofacial specialist. specialist. 41 st Fall Annual 41 st Fall Scientific Annual Scientific Symposium Symposium of the of American the American Society Society of of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS),13-14 October 2010, Chicago (IL), USA. 194

6 Upcoming invited lectures at: Association for Research in Vision and Ophthalmology of Asia (Asia-ARVO) Conference, January 2011, Singapore; Singapore. Congress of the African Society of Ophthalmic Plastic and Reconstructive Surgery (AFSOPRS), 8-9 April 2011, Cairo, Egypt. EUGOGO Russian course, University May of 2011, Moscow, University of May Moscow, 2011, Moscow, Russia. Congress of the European Society of Ophthalmology (SOE), 4-7 June 2011, Genève, Switzerland. 10 th th World Congress of the International Society of Dacryology and Dry Eye (ISD&DE), Manila, 30 Philippines, November November December , December Manila, 2011 Philippines. World Congress of Ophthalmology, February 2012, Abu Dhabi, United Arab Emirates. Publications 1. Barca L, Rizzo S, Fava PL, Baldeschi L, Torrazza C. Neovascolarizzazione retinica in paziente con sclerosi multipla. [Retinal neovascolarization in a patient with multiple sclerosis]. Annali di Ottalmologia e Clinica Oculistica 1993;2: Rizzo S, Baldeschi L, Frezzotti P, Torrazza C, Nardi M, Rose GE. A case of a late complication after naso-lacrimal duct intubation. Eye 1995;9: Baldeschi L, Rizzo S, Nardi M. Damage of foldable intraocular lenses by incorrect folder forceps. Am J Ophthalmol 1997;124: Romani A, Baldeschi L, Genovesi-Ebert F, Gremigni E, Ragone MC, Rizzo S, Nardi M. Ultrasonographic follow-up of primary choroideal malignant melanoma after proton beam irradiation therapy. Ophthalmologica 1998;212: Romani A, Baldeschi L, Genovesi-Ebert F, Gremigni E, Ragone MC, Rizzo S, Nardi M. Ultrasonographic and angiographic follow-up of primary choroideal malignant melanoma after proton beam irradiation therapy. Ophthalmologica 1998;212: Romani A, Baldeschi L, Genovesi-Ebert F, Gremigni E, Ragone MC, Rizzo S, Nardi M. Sensitivity and specificity of ultrasonography, fluorescein videoangiography, indocianine green videoangiography, magnetic resonance and radioimmunoscintigraphy in the diagnosis of primary choroidal malignant melanoma. Ophthalmologica 1998;212: Hintschich CR, Reithel E, Willekens B, Craig G, Bernatzky G, Baldeschi L, Collin JRO. Glassionomer implants and tissue aluminium levels: an animal study. Orbit 1997;16: Baldeschi L, Lupetti A, Nardi M, Hintschich C, Collin JRO. A comparison of skin storage methods for oculoplastic surgery. Eye 1998;12: Baldeschi L, Nardi M, Hintschich CR, Koornneef L. Anterior suspended flaps: a modified approach for external dacryocystorhinostomy. Br J Opthalmol 1998;82: Hintschich C, Zonneveld FW, Baldeschi L, Koornneef L. L. Langzeitergebnisse sekundärer orbitaimplantate [Long-term (Long-term results of secondary orbital implant). implant]. Ophthalmologe 1999;96: Baldeschi L, Nolst Trenité GJ, Hintschich C, Koornneef L. Intranasal ostium after external dacryocystorhinostomy and internal opening of the lacrimal canaliculi. Orbit 2000;19:

7 12. Hintschich C, Baldeschi L. Rehabilitation of anophthalmic patients. Results of a survey. Ophthalmologe 2001;98: Hintschich C, Zonneveld F, Baldeschi L, Bunce C, Koornneef L. Bony orbital development after early enucleation in humans. Br J Opthalmol 2001;85: Terwee CB, Dekker FW, Mourits MP, Gerding MN, Baldeschi L, Kalmann R, Prummel MF, Wiersinga WM. Interpretation and validity of changes in scores on the Graves ophthalmopathy quality of life questionnaire (GO-QOL) after different treatments. Clin Endocrinol 2001;54: Terwee CB, Dekker FW, Bonsel GJ, Heisterkamp SH, Prummel MF, Baldeschi L, Wiersinga WM. Facial disfigurement: is it in the eye of the beholder? A study in patients with Graves ophthalmopathy. Clin Endocrinol (Oxf) 2003;58: Wakelkamp IMMJ, Bakker O, Baldeschi L, Wiersinga WM, Prummel MF. TSH-R expression and cytokine profile in orbital tissue of active vs. inactive Graves' patients. Clin Endocrinol (Oxf) 2003;58: Prummel MF, Bakker A, Wiersinga WM, Baldeschi L, Mourits MP, Kendall-Taylor P, Perros P, Neoh C, Dickinson AJ, Lazarus JH, Lane CM, Heufelder AE, Kahaly GJ, Pitz S, Orgiazzi J, Hullo A, Pinchera A, Marcocci C, Sartini MS, Rocchi R, Nardi M, Krassas GE, Halkias A. Multi-center study on the characteristics and treatment strategies of patients with Graves' orbitopathy: the first European Group on Graves' Orbitopathy experience. Eur J Endocrinol 2003;148: Prummel MF, Terwee CB, Gerding MN, Baldeschi L, Mourits MP, Blank L, Dekker FW, Wiersinga WM. A randomised controlled trial of orbital radiotherapy versus sham irradiation in patients with mild Graves ophthalmopathy. J Clin Endocrinol Metab 2004;89: Baldeschi L, Macandie K, Hintschich CR. The length of unsutured mucosal margins in external dacryocystorhinostomy. Am J Ophthalmol 2004;138: Wakelkamp IMMJ, Baldeschi L, Saeed P, Mourits MP, Prummel MF, Wiersinga WM. Surgical or medical decompression as a first line treatment of optic neuropathy in Graves' ophthalmopathy? A randomized controlled trial. Clin Endocrinol (Oxf) 2005; 63: Baldeschi L, MacAndie K, Hintschich C, Wakelkamp IM, Prummel MF, Wiersinga WM. The removal of the deep lateral wall in decompression surgery: its contribution to exophthalmos reduction and influence on consecutive diplopia. Am J Ophthalmol 2005;140: Baldeschi L, Wakelkamp IMMJ, Lindeboom R, Prummel MF, Wiersinga WM. Early versus late orbital decompression in Graves orbitopathy: a retrospective study in 125 patients. Ophthalmology 2006;113: European Group of Graves' Orbitopathy, Perros P, Baldeschi L, Boboridis K, Dickinson AJ, Hullo A, Kahaly GJ, Kendall-Taylor P, Krassas GE, Lane CM, Lazarus JH, Marcocci C, Marino M, Mourits MP, Nardi M, Orgiazzi J, Pinchera A, Pitz S, Prummel MF, Wiersinga WM. A questionnaire survey on the management of Graves orbitopathy in Europe. Eur J Endocrinol 2006;155: Baldeschi L, Lindeboom R, MacAndie K, Wakelkamp IMMJ, Wiersinga WM, Hintschich C. The deep lateral wall in decompression surgery: reply of the author. Am J Ophthalmol 2006;142: European Group on Graves' Orbitopathy (EUGOGO), Wiersinga WM, Perros P, Kahaly GJ, Mourits MP, Baldeschi L, Boboridis K, Boschi A, Dickinson AJ, Kendall-Taylor P, Krassas GE, Lane CM, 196

8 Lazarus JH, Marcocci C, Marino M, Nardi M, Neoh C, Orgiazzi J, Pinchera A, Pitz S, Prummel MF, Sartini MS, Stahl M, von Arx G. Clinical assessment of patients with Graves orbitopathy: the European group for Graves orbitopathy (EUGOGO) recommendations to generalists, specialists and clinical researchers. Eur J Endocrinol 2006;155: McKeag D, Lane C, Lazarus JH, Baldeschi L, Boboridis K, Dickinson AJ, Hullo AI, Kahaly G, Krassas G, Marcocci C, Marinò M, Mourits MP, Nardi M, Neoh C, Orgiazzi J, Perros P, Pinchera A, Pitz S, Prummel MF, Sartini MS, Wiersinga WM; European Group on Graves' Orbitopathy (EUGOGO). Clinical Features of Dysthyroid Optic Neuropathy: A European Group on Graves' Orbitopathy (EUGOGO) Survey. Br J Ophthalmol 2007;91: Baldeschi L, Wakelkamp IMMJ, Lindeboom R, Prummel MF, Wiersinga WM. Timing of surgery for Graves orbitopathy: author reply. Ophthalmology 2007;114:393e Baldeschi L, Lupetti A, Vu P, Wakelkamp IMMJ, Prummel MF, Wiersinga WM. Reactivation of Graves orbitopathy after rehabilitative orbital decompression. Ophthalmology 2007;114: Le Moli R, Baldeschi L, Saeed P, Regensburg N, Mourits MP, Wiersinga WM. Determinants of liver function damage after high dosis IV corticosteroids for Graves orbitopathy. Thyroid 2007;17: Baldeschi L, Bisschop PH LT, Wiersinga WM. Supernumerary extraocular muscle in Graves orbitopathy. Thyroid 2007;17: Baldeschi L, Lupetti A, Wiersinga WM. Graves orbitopathy presenting after botulinum toxin injections. Ophth plast Rec Surg 2007;23: Baldeschi L, MacAndie K, Koetsier E, Blank LE, Wiersinga WM. The influence of previous orbital radiotherapy on the outcome of rehabilitative decompression surgery in Graves orbitopathy. Am J Ophthalmol 2008;145: Bartalena L, Baldeschi L, Dickinson A, Eckstein A, Kendall-Taylor P, Marcocci C, Mourits M, Perros P, Boboridis K, Boschi A, Currò N, Daumerie C, Kahaly GJ, Krassas GE, Lane CM, Lazarus JH, Marinò M, Nardi M, Neoh C, Orgiazzi J, Pearce S, Pinchera A, Pitz S, Salvi M, Sivelli P, Stahl M, von Arx G, Wiersinga WM; European Group on Graves' Orbitopathy (EUGOGO). Consensus statement of the European Group on Graves orbitopathy (EUGOGO) on management of Graves orbitopathy. Eur J Endocrinol 2008;158: Bartalena L, Baldeschi L, Dickinson AJ, Eckstein A, Kendall-Taylor P, Marcocci C, Mourits MP, Perros P, Boboridis K, Boschi A, Currò N, Daumerie C, Kahaly GJ, Krassas G, Lane CM, Lazarus JH, Marinò M, Nardi M, Neoh C, Orgiazzi J, Pearce S, Pinchera A, Pitz S, Salvi M, Sivelli P, Stahl M, von Arx G, Wiersinga WM. Consensus statement of the European Group on Graves orbitopathy (EUGOGO) on management of Graves orbitopathy. Thyroid 2008;18: Wiersinga WM, Bleumink M, Saeed P, Baldeschi L, Prummel MF. Is sleeping position related to asymmetry in bilateral Graves ophthalmopathy? Thyroid 2008;18: Regensburg NI, Kok PH, Zonneveld FW, Baldeschi L, Saeed P, Wiersinga WM, Mourits MP. A standardized CT-based method for the calculation of orbital soft tissue volumes. Invest Ophthalmol Vis Sci 2008;49: Baldeschi L. Correction of lid retraction and exophthalmos. Dev Ophthalmol. 2008;41:

9 38. Baldeschi L, Saeed P. Commentary. Surg Neurol. 2008;70 Suppl 1:S1: European Group on Graves' Orbitopathy (EUGOGO), Mourits MP, Bijl H, Altea MA, Baldeschi L, Boboridis K, Currò N, Dickinson AJ, Eckstein A, Freidel M, Guastella C, Kahaly GJ, Kalmann R, Krassas GE, Lane CM, Lareida J, Marcocci C, Marino M, Nardi M, Mohr Ch, Neoh C, Pinchera A, Orgiazzi J, Pitz S, Saeed P, Salvi M, Sellari-Franceschini S, Stahl M, von Arx G, Wiersinga WM. Outcome of orbital decompression for disfiguring proptosis in patients with Graves orbitopathy using various surgical procedures. Br J Ophthalmol 2009;93: Vardizer Y, Lupetti A, Vandelanotte S, Lankester AC, Wiersinga WM, Baldeschi L. Graves orbitopathy in a patient with adrenoleukodystropy after bone marrow transplantation. Eur J Endocrinol 2009;161: Saeed P, Tanck MW, Freling N, Baldeschi L, Mourits MP, Bennink RJ. Somatostatin receptor scintigraphy for optic nerve sheat meningiomas. Ophthalmology 2009:116: Blank LE, Koedooder K, van der Grient HN, Wolffs NA, van de Kar M, Merks JH, Pieters BR, Saeed P, Baldeschi L, Freling NJ, Koning CC. Brachytherapy as part of the multidisciplinary treatment of childhood rhabdomyosarcomas of the orbit. Int J Radiat Oncol Biol Phys 2010;77: Regensburg NI, Wiersinga WM, van Velthoven ME, Berendschot TT, Zonneveld FW, Baldeschi L, Saeed P, Mourits MP. Age and gender-specific reference values of orbital fat- and muscle volumes in Caucasians. Br J Ophthalmol Jun 7 [Epub ahead of print] 44. Baldeschi L, Saeed P, Regensburg NI, Zacharopoulos I, Wiersinga WM. Amputation Traumatic neuroma of the infraorbital nerve subsequent to inferomedial orbital decompression for Graves orbitopathy. Eur J Ophthalmol 2010;20: Lazarus J, Bartalena L, Marcocci C, Kahaly GJ, Krassas G, Wiersinga WM, Baldeschi L, Boboridis K, Boschi A, Currò N, Daumerie C, Dickinson AJ, Eckstein A, Kendall-Taylor P, Lane CM, Ludgate ME, Mann K, Marinò M, Mourits MP, Nardi M, Neoh C, Orgiazzi J, Pearce S, Perros P, Pinchera A, Pitz S, Salvi M, Sivelli P, Stahl M, von Arx G. Glucocorticoid administration for Graves' hyperthyroidism treated by radioiodine. A questionnaire survey among members of the European Thyroid Association. J Endocrinol Invest 2010;33: Baldeschi L. Small versus coronal incision orbital decompression in Graves orbitopathy. Orbit 2010;29: *** *** *** 47. Baldeschi L, Nieuwendaal C. Kanker van de oog en oogkas. [Cancer of the eye and orbit]. In: Veenhof CH, Voûte PA, editors. Behandeling van kanker [Treatment of the cancer]. cancer]. Houten: Bohn Stafleu Van Loghum, 2000: Baldeschi L. Correction of lid retraction and exophthalmos. In Brewitt H, Geerling G, editors. Scientific evidence and guidelines for the clinical management of dry eye associated ocular surface disease. Basel: Karger, 2007: Baldeschi L. Orbital decompressions: status of the art and unresolved issues. In: Guthoff RF, Katowitz JA, editors. Essential in Ophthalmology, Oculoplastics and Orbit. Berlin: Springer, 2007:

10 50. Baldeschi L. Rehabilitative surgery. In: Wiersinga WM, Kahaly GJ, editors. Graves Orbitopathy A Multidisciplinary Approach. Basel: Karger, 2007: Baldeschi L. Orbital decompression. In: Wiersinga WM, Kahaly GJ, editors. Graves Orbitopathy A Multidisciplinary Approach. Basel: Karger, 2007: Salvi M, Baldeschi L. Future developments. In: Wiersinga WM, Kahaly GJ, editors. Graves Orbitopathy A Multidisciplinary Approach. Basel: Karger, 2007: Baldeschi L. Patologie di interesse orbito oftalmoplastico: indicazioni e principi di trattamento [Orbital diseases: indications and principles of treatment]. Rome: I.N.C. Innovation-News- Communication, 2010: Baldeschi L. Orbitopatia tiroide correlata. [Thyroid Related Orbitopathy] In: Baldeschi L, editor. Patologie di interesse orbito oftalmoplastico: indicazioni e principi di trattamento, [Orbital diseases: indications and principles of treatment]. Rome: I.N.C. Innovation-News-Communication, 2010: Baldeschi L. Rehabilitative surgery. In: Wiersinga WM, Kahaly G, editors. Graves Orbitopathy A Multidisciplinary Approach - Questions and Answers, 2 nd edition. Basel: Karger, 2010: Baldeschi L. Orbital decompression. In: Wiersinga WM, Kahaly G, editors. Graves Orbitopathy A Multidisciplinary Approach - Questions and Answers, 2 nd edition. Basel: Karger, 2010: Baldeschi L. Future developments. In: Wiersinga WM, Kahaly G, editors. Graves Orbitopathy A Multidisciplinary Approach - Questions and Answers, 2 nd edition. Basel: Karger, 2010: Baldeschi L. Functional and rehabilitative surgery of Graves orbitopathy. In: Spaeth GL, editor. Ophthalmic Surgery: Principles and Practice, Atlas and Text Book, 4 th edition. Elsevier Science, Philadelpia, USA. (in press) 199

11 It s what you do next that counts, ad maiora!